AutismKB 2.0

Annotation Detail for AEBP1


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Basic Information Top
Gene Symbol:AEBP1 ( ACLP,FLJ33612 )
Gene Full Name: AE binding protein 1
Band: 7p13
Quick LinksEntrez ID:165; OMIM: 602981; Uniprot ID:AEBP1_HUMAN; ENSEMBL ID: ENSG00000106624; HGNC ID: 303
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of AEBP1 mRNAincreases expression 17484886
C014347 decitabine decitabine affects the expression of AEBP1 mRNAaffects expression 17145863
C014347 decitabine [decitabine affects the methylation of AEBP1 protein] which affects the expression of AEBP1 mRNAaffects expression|affects methylation 18381416
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
D004041 Dietary Fats Dietary Fats results in increased expression of AEBP1 mRNAincreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of AEBP1 mRNAincreases expression 17005392
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of AEBP1 mRNAdecreases expression 17557909
15576828
D019469 Indinavir [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
C041786 palm oil palm oil results in increased expression of AEBP1 mRNAincreases expression 18042831
D020849 Raloxifene Raloxifene results in increased expression of AEBP1 mRNAincreases expression 15576828
C010327 salinomycin salinomycin results in decreased expression of AEBP1 mRNAdecreases expression 19682730
D019258 Saquinavir [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
C025643 vinclozolin vinclozolin affects the expression of AEBP1 mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of AEBP1 mRNAincreases expression 19244175
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNAaffects cotreatment|increases expression 16931933
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.909612607
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8214692618
MESH:D000419 Albuminuria Raloxifene 4.6617308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5515800139
MESH:D000686 Amyloidosis Diethylstilbestrol 4.5415469931
MESH:D001008 Anxiety Disorders vinclozolin 3.6819015723
MESH:D001161 Arteriosclerosis Dietary Fats 10.1515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 10.1511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6915885639
MESH:D001930 Brain Injuries Raloxifene 4.5516580743
MESH:D001943 Breast Neoplasms decitabine 2.3919208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 2.3920435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.3915324884 17129689
MESH:D001943 Breast Neoplasms Raloxifene 2.3917049068 16837676 17440819 16912660 17242785 17595753 15775269 17952589 15758505 15572757 17893378 17261762
MESH:D001943 Breast Neoplasms salinomycin 2.3919682730
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 10.1816227642 10355542 15673190 16192424 15700767 16050911 15721981 3786805 18705752 16011737 16097048 16124888
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 10.1816050911
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.1918788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 3.1916924424 15948411
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6119215824
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 4.1217572228
MESH:D002318 Cardiovascular Diseases Raloxifene 3.4815775269
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9111677210 17110522 16919318 17333356 17681005 15861022 16105132
MESH:D003072 Cognition Disorders Raloxifene 4.6915800139
MESH:D003110 Colonic Neoplasms decitabine 2.3417616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9119769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 11.5916002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 11.5914966744
MESH:D003865 Depressive Disorder, Major Raloxifene 4.2117474826
MESH:D003928 Diabetic Nephropathies Raloxifene 3.9815920148 17308373 17451421
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.0511566570 16227642 7179309 15998439 2869522 3786805 15027814 3732212 19336974 6623471 6884620 16177239 10092053 7120509 4309450 19085960 7440962 10915739 9327722 21278145 15968718 17522070
MESH:D004362 Drug Toxicity Lamivudine 8.9215040536
MESH:D004362 Drug Toxicity Zidovudine 8.9215040536
MESH:D050171 Dyslipidemias Dietary Fats 3.4918367378
MESH:C538011 Eales disease Vitamin E 4.809068938
MESH:D004487 Edema Raloxifene 3.3915860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.3312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 9.3315845917
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.2119294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.7716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.5016804899 15700306
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.3016045604 17595544 12631006 16239168 61145 12795759 19224547 15959796
MESH:D005234 Fatty Liver Dietary Fats 25.3019004024 19551842 17967931 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.3015345470
MESH:D005234 Fatty Liver Raloxifene 25.3017473493
MESH:D005234 Fatty Liver Zidovudine 25.3018299183
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.6915751030 16534752 16611131 16002989 16513791
MESH:D005355 Fibrosis Carbon Tetrachloride 9.0518705752
MESH:D005355 Fibrosis Dietary Fats 9.0518296743
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.0216973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.4016417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.0316452187
MESH:D006258 Head and Neck Neoplasms decitabine 3.5219215824
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0116080930
MESH:D006331 Heart Diseases Raloxifene 3.5711110106
MESH:D006402 Hematologic Diseases Zidovudine 4.7712579204
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6619110552 19900420
MESH:D006509 Hepatitis B Lamivudine 5.1517703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 5.1516476009 15631357 15274664 15309715 12044531
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7216863852 16490937
MESH:D015658 HIV Infections Indinavir 15.7515388451 11363243 11141242
MESH:D015658 HIV Infections Lamivudine 15.759296927 11141242 20032539 17530837
MESH:D015658 HIV Infections Saquinavir 15.7515388451 11141242
MESH:D015658 HIV Infections Zidovudine 15.7517358032 11698656 11141242 20032539 11363243
MESH:D019584 Hot Flashes Vitamin E 4.0714716179
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.6116899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6521332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.6721332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.5112960047 14722030
MESH:D006973 Hypertension Raloxifene 2.8817577099 15787275
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1615338365
MESH:D007021 Hypospadias Diethylstilbestrol 11.4916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.4916945680 16569931
MESH:D007246 Infertility Diethylstilbestrol 4.4215036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male decitabine 11.4517581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.4517937319
MESH:D007248 Infertility, Male vinclozolin 11.4516467254
MESH:D007249 Inflammation Dietary Fats 2.4620412841
MESH:D007251 Influenza, Human Vitamin E 4.3116624496
MESH:D007333 Insulin Resistance Dietary Fats 3.1418457598 11836018
MESH:D007674 Kidney Diseases Vitamin E 2.8312488133
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.9915003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Zidovudine 7.9912579204
MESH:D007859 Learning Disorders Diethylstilbestrol 4.1317184923
MESH:D007889 Leiomyoma Raloxifene 4.5516973256
MESH:D007938 Leukemia decitabine 3.1019235587 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.4720370541
MESH:D007951 Leukemia, Myeloid decitabine 4.0618454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.3918704418 19010910 17679729 19387464 18460780 18206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.5618055864
MESH:D007984 Leydig Cell Tumor vinclozolin 4.8116417039
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.7216943688 17334410 17157831 17174718 11903743 16221502 21278145 11408273 16239168
MESH:D008103 Liver Cirrhosis Dietary Fats 6.7218296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.5417708605 15925388 18279442 18317297 18210741 17869086 17721639 12389079 17805973 12445418 17761835 12649538 15362042 17922224 18376398 20821823 12586293 15931870 10355542 18481824 15123356 17823541 18205269 18166357 18395914 14748882 15818738 18277467 18251166 17944888 12741479 17698563 16248980 18705752 15996030 16116963 17714472 16136751 15338365 18054572 18412020 15673190 18339082 14620537 12667390 16015684 18187930 12546737 16011737 15730626 12445421 14724832 17976157 18472332 17640975 14512876 15876570 17481882 18395095 14716496 12609069 12666154 18420326 12632514 16027843 11481614 15959796 15893842 18263696 18472094 14716833 15370692 18429990 17557913 18156304 15650968 12958196 15057751 17631135 17565644 13678700 18006644 12632512 12898905 16192424 16638106 15052691 17900296 17766677 18418968 16097048 17525996 16033810
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.5416169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.0916246199 16964402 15720792 15830285 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2415123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7416899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.8019294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 4.8016712894 15890375
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.6412014681 15583823
MESH:D008171 Lung Diseases Vitamin E 3.2116863852
MESH:D008175 Lung Neoplasms Vitamin E 2.7811062179
MESH:D008175 Lung Neoplasms Zidovudine 2.7818800350
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.2315166399
MESH:D008223 Lymphoma decitabine 7.8619470736
MESH:D008223 Lymphoma Diethylstilbestrol 7.8615700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.6116002989
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 3.8019682730
MESH:D008545 Melanoma decitabine 2.2516505122 17785578
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.9317358032
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.6515863610
MESH:D009101 Multiple Myeloma decitabine 7.6318172295
MESH:D009101 Multiple Myeloma Raloxifene 7.6316497877
MESH:D009164 Mycobacterium Infections Indinavir 5.5121442799
MESH:D009190 Myelodysplastic Syndromes decitabine 3.4116882708 19157545 19010910 18608210
MESH:D009232 Myxoma Raloxifene 5.6516343187
MESH:D009369 Neoplasms decitabine 5.4019470736 17925555 19116145
MESH:D009369 Neoplasms Diethylstilbestrol 5.4015313581
MESH:D009421 Nervous System Malformations Diethylstilbestrol 4.2011399458
MESH:D009765 Obesity Dietary Fats 2.3019632207 20132043 18674790 20518802 21332399 17217161 11836018 16723640 18457598
MESH:D010024 Osteoporosis Raloxifene 3.4215775268 19059307 17882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.2917893378 17823083 15758505 15579764
MESH:D010051 Ovarian Neoplasms decitabine 2.6619259094 19331143
MESH:D010190 Pancreatic Neoplasms decitabine 2.7819294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.2714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.7415687265 16977796
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 10.1117184923
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 10.1119015723 18042343 18220299
MESH:D055728 Primary Myelofibrosis decitabine 4.8017616702
MESH:D011469 Prostatic Diseases vinclozolin 5.0218220299
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.6715846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Raloxifene 2.6716536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6715084515
MESH:D011472 Prostatitis vinclozolin 5.0218629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.3916919318 15861022
MESH:D011693 Purpura Raloxifene 5.6515770314
MESH:D012206 Rhabdomyolysis Lamivudine 5.629296927
MESH:D012208 Rhabdomyosarcoma decitabine 4.4619155313
MESH:D012871 Skin Diseases Vitamin E 2.4518709164
MESH:D013088 Spermatocele Diethylstilbestrol 12.0416002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 12.0416709447
MESH:D013274 Stomach Neoplasms decitabine 2.8119037991
MESH:D013274 Stomach Neoplasms Zidovudine 2.8117696246
MESH:D020521 Stroke Raloxifene 8.8616837676
MESH:D020521 Stroke Vitamin E 8.8616517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013964 Thyroid Neoplasms decitabine 3.3717967635
MESH:D013978 Tibial Fractures Raloxifene 5.3119048282
MESH:D001749 Urinary Bladder Neoplasms decitabine 8.5919087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.5916712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 8.5917572228
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.0816175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.2714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.6915809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.6914692618
MESH:D014604 Uveal Neoplasms decitabine 5.0117785578
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 11.3816002989 16513791
MESH:D014625 Vaginal Neoplasms Zidovudine 11.3812579204
MESH:D054556 Venous Thromboembolism Raloxifene 5.3116837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5914671159 15869587
MESH:D014846 Vulvar Neoplasms Raloxifene 5.6516343187
MESH:D015430 Weight Gain Dietary Fats 3.7916723640
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24604
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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