Annotation Detail for GIMAP7
Basic Information Top
| Gene Symbol: | GIMAP7 ( IAN7,MGC27027,hIAN7 ) |
|---|---|
| Gene Full Name: | GTPase, IMAP family member 7 |
| Band: | 7q36.1 |
| Quick Links | Entrez ID:168537; OMIM: NA; Uniprot ID:GIMA7_HUMAN; ENSEMBL ID: ENSG00000179144; HGNC ID: 22404 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C014949 | acetylhydrazine | acetylhydrazine results in decreased expression of GIMAP7 mRNA | decreases expression | 15282401 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in increased expression of GIMAP7 mRNA | increases expression | 17942915 |
| D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GIMAP7 mRNA] | decreases reaction|increases expression | 17942915 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of GIMAP7 mRNA | decreases expression | 17426115 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.64 | 18653653 | |
| MESH:D000236 | Adenoma | Diethylnitrosamine | 3.08 | 10737359 6695378 | |
| MESH:D018248 | Adenoma, Liver Cell | Diethylnitrosamine | 12.71 | 19061943 19052882 17162532 17620307 18056438 16434500 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 12.71 | 16434500 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.63 | 19483382 | |
| MESH:D001943 | Breast Neoplasms | Diethylnitrosamine | 2.19 | 17474063 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylnitrosamine | 1.88 | 16288022 20007298 17173139 3581430 3084413 19519916 18788625 17761372 18210153 10737359 19701751 16681979 19919837 16779866 18506893 19394651 16328049 18494052 16502159 19418558 19539802 16807293 19052882 20084675 17978847 20524982 20514400 20432363 19171122 17428255 17138121 18056438 20727157 18978308 16878318 19822196 16569478 20101231 16830150 16698587 16540662 18785209 10672840 11831363 20214788 18665156 17055752 19107877 19208518 20935162 16935385 19383236 17162532 18971187 20512989 19335982 18691550 21159647 18393292 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Diethylnitrosamine | 3.15 | 7505956 17174075 21159647 2727394 | |
| MESH:D018281 | Cholangiocarcinoma | Diethylnitrosamine | 4.10 | 19052882 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.15 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.59 | 18249437 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Diethylnitrosamine | 2.27 | 20387270 | |
| MESH:D056486 | Drug-Induced Liver Injury | Diethylnitrosamine | 2.15 | 19107877 | |
| MESH:D004487 | Edema | pirinixic acid | 2.96 | 12083418 | |
| MESH:D004931 | Esophageal Achalasia | Diethylnitrosamine | 5.98 | 16302075 | |
| MESH:D005234 | Fatty Liver | Diethylnitrosamine | 9.33 | 21071580 20387270 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 9.33 | 20131406 19236843 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.78 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.64 | 19176532 19772884 16221962 18467677 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.63 | 20558911 | |
| MESH:D007249 | Inflammation | Diethylnitrosamine | 2.57 | 18785209 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.90 | 16306350 | |
| MESH:D008103 | Liver Cirrhosis | Diethylnitrosamine | 3.03 | 18407596 19638242 20032147 18522880 18665156 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Diethylnitrosamine | 2.18 | 17034775 | |
| MESH:D008113 | Liver Neoplasms | Diethylnitrosamine | 4.88 | 19638242 19850985 19499222 2862719 21278145 20405173 18644402 20492335 19426721 10737359 20452335 19090486 12112319 9163691 18754104 20118626 19690152 19551842 19294768 20434301 20137499 20501860 12771043 19427195 19996281 18978307 20101389 19812893 19255062 16942905 20583210 19256749 15175105 21071580 19254457 19073162 18648771 19833225 18977376 21047994 15885732 21167192 19642983 2422723 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 4.88 | 20007298 16377806 15890375 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Diethylnitrosamine | 2.88 | 19539802 9362446 16267830 18093689 19009564 18308698 18775883 19004024 19519916 16842330 17174075 18253720 19126423 21159647 3124819 18282651 18544905 2563599 17942915 18164116 18079962 17854601 | |
| MESH:D008175 | Lung Neoplasms | Diethylnitrosamine | 1.77 | 21163286 20970405 20512841 6695378 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.16 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.29 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.29 | 16411023 | |
| MESH:D009362 | Neoplasm Metastasis | Diethylnitrosamine | 2.70 | 9029167 3581430 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.12 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Diethylnitrosamine | 3.73 | 20387270 | |
| MESH:D009461 | Neurologic Manifestations | Diethylnitrosamine | 5.98 | 20387270 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.89 | 20558911 | |
| MESH:D010190 | Pancreatic Neoplasms | Diethylnitrosamine | 2.54 | 16540662 | |
| MESH:D011230 | Precancerous Conditions | Diethylnitrosamine | 3.97 | 2563599 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.56 | 19058328 | |
| MESH:D013274 | Stomach Neoplasms | Diethylnitrosamine | 1.76 | 18456281 | |
| MESH:D013964 | Thyroid Neoplasms | Diethylnitrosamine | 3.32 | 7505956 |
| No data |