Annotation Detail for ARX
Basic Information
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| Gene Symbol: | ARX ( CT121,ISSX,MRX29,MRX32,MRX33,MRX36,MRX38,MRX43,MRX54,MRX76,MRX87,MRXS1,PRTS ) |
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| Gene Full Name: | aristaless related homeobox |
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| Band: | Xp21.3 |
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| Quick Links | Entrez ID:170302; OMIM: 300382; Uniprot ID:ARX_HUMAN; ENSEMBL ID: ENSG00000004848; HGNC ID: 18060 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Desease Name |
|---|
| Proud syndrome |
| Epilepsy, myoclonic, with mental retardation and spasticity |
| Hydranencephaly with abnormal genitalia |
| Mental retardation, X-linked 29 |
| Epileptic encephalopathy, early infantile, 1 |
| Lissencephaly, X-linked 2 |
| Mental retardation, X-linked 36/43/54 |
| Partington syndrome |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of ARX mRNA | affects expression | 17562736
|
| D001104 |
Arbutin |
Arbutin results in decreased expression of ARX mRNA | decreases expression | 17103032
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.91 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.41 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.83 | 10977129 |
| OMIM:300004 |
CORPUS CALLOSUM, AGENESIS OF, WITH ABNORMAL GENITALIA |
marker/mechanism |
|
| |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.68 | 19739265 19164858 11461765 15619225 10915739 19923254 11287661 2444490 17906064 14550746 18713872 11739529 19416960 11743745 18071297 19420014 12153990 11529661 10663392 12540782 16781746 12594235 16109766 16485898 14986274 19370779 12705907 16227642 12392966 11834606 17522070 10774834 16393943 15968718 19085960 12958197 11421492 16081117 14725611 16177239 17562736 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
5.17 | 19426721 |
| OMIM:308350 |
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1 |
marker/mechanism |
|
| |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.74 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.11 | 16870215 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.44 | 15629191 12587719 |
| OMIM:300215 |
LISSENCEPHALY, X-LINKED, 2 |
marker/mechanism |
|
| |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 12969438 11587558 19460945 16611625 19784758 12587719 16610002 19014921 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.74 | 16871587 17185352 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.33 | 19513568 |
| MESH:D038901 |
Mental Retardation, X-Linked |
marker/mechanism |
|
| |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.31 | 18514411 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.82 | 16870215 |
| MESH:C536300 |
Partington X-linked mental retardation syndrome |
marker/mechanism |
|
| |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.58 | 10982225 |
PharmGKB Accession:PA25024
| Releated disease ID |
Related disease Name |
| PA152530805 | Early Infantile Epileptic Encephalopathy With Suppression-Burst Pattern |
Related Pathway Information