AutismKB 2.0

Annotation Detail for SSBP4


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Basic Information Top
Gene Symbol:SSBP4 ( MGC3181 )
Gene Full Name: single stranded DNA binding protein 4
Band: 19p13.1
Quick LinksEntrez ID:170463; OMIM: 607391; Uniprot ID:SSBP4_HUMAN; ENSEMBL ID: ENSG00000130511; HGNC ID: 15676
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SSBP4 mRNAaffects expression 17562736
C015001 arsenite arsenite results in decreased expression of SSBP4 mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of SSBP4 mRNA]affects reaction|decreases expression 18929588
D017313 Fenretinide Fenretinide results in decreased expression of SSBP4 mRNAdecreases expression 16671099
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of SSBP4 mRNAaffects cotreatment|increases expression 17183730
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of SSBP4 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.028875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3019490988
MESH:D000230 Adenocarcinoma Fenretinide 3.1710697514
MESH:D000550 Amblyopia Valproic Acid 5.8517688650
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.8617497229
MESH:D001321 Autistic Disorder Acetaminophen 1.8618445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8620603192 18396377 16609825 18940202 18177632 17507914 18558336 17157402 18985861 17688650 15238991 19232924 18775368 19460635 18316065
MESH:D001714 Bipolar Disorder Valproic Acid 3.2317594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.618888407
MESH:D001932 Brain Neoplasms Fenretinide 4.7016187019
MESH:D001943 Breast Neoplasms Fenretinide 3.1216601279
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.323084413
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 3.3217159502 16270382
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 3.2516274795
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 6.0216154183
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8120734317
MESH:D003110 Colonic Neoplasms arsenite 2.6315037631
MESH:D015179 Colorectal Neoplasms Fenretinide 2.6917273769
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9016575769 8888407 17688650
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0716109766 11287661 12594235 10663392 12392966 12153990 2444490 16227642 15619225 10915739 12958197 11834606 16081117 18713872 10774834 14725611 12540782 17906064 19923254 19739265 11743745 18071297 14550746 16781746 19085960 11461765 11529661 12705907 17522070 19416960 16177239 19420014 16393943 15968718 19370779 16485898 11421492 19164858 14986274 11739529 17562736
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.071733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004421 Dystonia Valproic Acid 4.451851702
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.6417275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.533922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.0918234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.917562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.787750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.603659116
MESH:D005234 Fatty Liver arsenite 9.3618296743
MESH:D005234 Fatty Liver Valproic Acid 9.3619224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.5016575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.578888407 18558336
MESH:D005355 Fibrosis arsenite 4.5518296743
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005909 Glioblastoma Fenretinide 4.1016187019
MESH:D006849 Hydrocephalus Valproic Acid 5.4117688650
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 5.1116612254
MESH:D007674 Kidney Diseases Acetaminophen 2.3815629191 12587719
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1917596541 16294345
MESH:D007972 Leukoplakia, Oral Fenretinide 6.6616707609
MESH:D008103 Liver Cirrhosis arsenite 3.5918296743
MESH:D008107 Liver Diseases Acetaminophen 1.6912969438 11587558 19014921 16611625 16610002 12587719 19784758 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.8717228818
MESH:D008175 Lung Neoplasms arsenite 2.3616809336
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 3.7810697514
MESH:D008545 Melanoma Fenretinide 2.8616270382
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008881 Migraine Disorders Valproic Acid 3.4418803445 18765137
MESH:D009062 Mouth Neoplasms Fenretinide 4.5916274795
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.408888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3317596541
MESH:D009369 Neoplasms Fenretinide 3.4415958647 17353921
MESH:D009389 Neovascularization, Pathologic arsenite 4.9515738583
MESH:D009436 Neural Tube Defects Valproic Acid 3.3416359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 6.2216303764
MESH:D010051 Ovarian Neoplasms Fenretinide 3.3116133793
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Fenretinide 3.4515580305
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.3720603192
MESH:D011471 Prostatic Neoplasms Fenretinide 4.0417024972
MESH:D019310 Pseudolymphoma Valproic Acid 5.1512752131 11422049
MESH:D012162 Retinal Degeneration Fenretinide 4.6616303925
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.5819155313
MESH:D012559 Schizophrenia Valproic Acid 2.1019110320 15737665
MESH:D012640 Seizures Valproic Acid 2.9611738929 14763951 1511512 16876388 11044598 15475178 3137016 17978042
MESH:D012878 Skin Neoplasms Fenretinide 3.6316467112
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0619490988
MESH:D013226 Status Epilepticus Valproic Acid 5.1512833885
MESH:D014178 Translocation, Genetic Valproic Acid 5.8517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.063119515
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 3.4116720286
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.138888407
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 4.9116154183
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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