Annotation Detail for COMMD6
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004041 |
Dietary Fats |
Dietary Fats results in decreased expression of COMMD6 mRNA | decreases expression | 18042831
|
| D006830 |
Hydralazine |
[Hydralazine co-treated with Valproic Acid] results in increased expression of COMMD6 mRNA | affects cotreatment|increases expression | 17183730
|
| C051890 |
irinotecan |
irinotecan metabolite results in increased expression of COMMD6 mRNA | increases expression | 15956246
|
| C051890 |
irinotecan |
irinotecan results in increased expression of COMMD6 mRNA | increases expression | 15956246
|
| C041786 |
palm oil |
palm oil results in decreased expression of COMMD6 mRNA | decreases expression | 18042831
|
| D014635 |
Valproic Acid |
[Hydralazine co-treated with Valproic Acid] results in increased expression of COMMD6 mRNA | affects cotreatment|increases expression | 17183730
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
4.02 | 8875741 |
| MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
4.30 | 19490988 |
| MESH:D000550 |
Amblyopia |
|
Valproic Acid |
5.85 | 17688650 |
| MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
3.86 | 17497229 |
| MESH:D001161 |
Arteriosclerosis |
|
Dietary Fats |
4.37 | 15238619 |
| MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
1.98 | 18396377 17507914 19232924 17157402 18940202 18558336 19460635 17688650 15238991 18985861 20603192 18316065 16609825 18775368 18177632 |
| MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
3.23 | 20046352 17594078 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
3.61 | 8888407 |
| MESH:D001943 |
Breast Neoplasms |
|
Dietary Fats |
2.25 | 20435547 |
| MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.81 | 20734317 |
| MESH:D003110 |
Colonic Neoplasms |
|
irinotecan |
2.64 | 17725105 17287894 |
| MESH:D015179 |
Colorectal Neoplasms |
|
irinotecan |
2.36 | 17454858 16391804 18259882 17159606 18509181 15273666 16303861 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
1.90 | 17688650 8888407 16575769 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
2.25 | 19641884 1733752 |
| MESH:D050171 |
Dyslipidemias |
|
Dietary Fats |
3.70 | 18367378 |
| MESH:D004421 |
Dystonia |
|
Valproic Acid |
4.45 | 1851702 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
4.64 | 3659116 17275665 |
| MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
4.53 | 16628512 3922381 |
| MESH:D004827 |
Epilepsy |
|
Valproic Acid |
3.09 | 18234410 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
3.91 | 6426943 6254150 7562514 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.78 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
4.60 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Dietary Fats |
9.16 | 19004024 19551842 17967931 18296743 |
| MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
9.16 | 19224547 14986274 |
| MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
5.50 | 16575769 |
| MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
4.57 | 18558336 8888407 |
| MESH:D005355 |
Fibrosis |
|
Dietary Fats |
4.01 | 18296743 |
| MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
5.41 | 17688650 |
| MESH:D006937 |
Hypercholesterolemia |
|
Dietary Fats |
3.97 | 21332399 |
| MESH:D006949 |
Hyperlipidemias |
|
Dietary Fats |
4.02 | 21332399 |
| MESH:D046110 |
Hypertension, Pregnancy-Induced |
|
Hydralazine |
5.11 | 16612254 |
| MESH:D007249 |
Inflammation |
|
Dietary Fats |
2.59 | 20412841 |
| MESH:D007333 |
Insulin Resistance |
|
Dietary Fats |
3.32 | 11836018 18457598 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
2.19 | 16294345 17596541 |
| MESH:D008103 |
Liver Cirrhosis |
|
Dietary Fats |
3.05 | 18296743 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
4.87 | 17228818 |
| MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
3.44 | 18803445 18765137 |
| MESH:D052016 |
Mucositis |
|
irinotecan |
5.55 | 17159606 |
| MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
4.40 | 8888407 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
3.33 | 17596541 |
| MESH:D009362 |
Neoplasm Metastasis |
|
irinotecan |
3.28 | 18259882 |
| MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
3.34 | 8888407 16359493 |
| MESH:D009447 |
Neuroblastoma |
|
irinotecan |
3.64 | 8761367 |
| MESH:D017599 |
Neuroectodermal Tumors |
|
irinotecan |
5.27 | 8761367 |
| MESH:D009765 |
Obesity |
|
Dietary Fats |
2.35 | 17217161 19632207 20518802 18674790 18457598 16723640 21332399 11836018 20132043 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
4.37 | 20603192 |
| MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
5.15 | 12752131 11422049 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
4.58 | 19155313 |
| MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.10 | 19110320 15737665 |
| MESH:D012640 |
Seizures |
|
Valproic Acid |
2.96 | 3137016 14763951 11044598 17978042 1511512 16876388 11738929 15475178 |
| MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
4.06 | 19490988 |
| MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
5.15 | 12833885 |
| MESH:D013274 |
Stomach Neoplasms |
|
irinotecan |
2.36 | 15723263 |
| MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
5.85 | 17262798 |
| MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
5.06 | 3119515 |
| MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
5.13 | 8888407 |
| MESH:D015430 |
Weight Gain |
|
Dietary Fats |
4.06 | 16723640 |
Related Pathway Information