Annotation Detail for DMWD
Basic Information
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| Desease Name |
|---|
| reduced level of RNfrom the DMWD allele adjacent to the expanded repeat |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of DMWD mRNA | affects expression | 17562736
|
| C068073 |
Am 580 |
Am 580 results in decreased expression of DMWD mRNA | decreases expression | 16982809
|
| C051890 |
irinotecan |
irinotecan metabolite results in increased expression of DMWD mRNA | increases expression | 15956246
|
| C051890 |
irinotecan |
irinotecan results in increased expression of DMWD mRNA | increases expression | 15956246
|
| C089730 |
rosiglitazone |
rosiglitazone results in decreased expression of DMWD mRNA | decreases expression | 16982809
|
| D012643 |
Selenium |
Selenium results in increased expression of DMWD mRNA | increases expression | 19244175
|
| D018038 |
Sodium Selenite |
Sodium Selenite results in increased expression of DMWD mRNA | increases expression | 18175754
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000544 |
Alzheimer Disease |
|
rosiglitazone |
2.90 | 19621015 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.36 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
8.24 | 10977129 |
| MESH:D002386 |
Cataract |
|
Am 580 |
8.24 | 17460283 |
| MESH:D019457 |
Chromosome Breakage |
|
Sodium Selenite |
5.17 | 15894690 |
| MESH:D003092 |
Colitis |
|
Am 580 |
11.39 | 17035595 |
| MESH:D003092 |
Colitis |
|
Selenium |
11.39 | 17936198 |
| MESH:D003110 |
Colonic Neoplasms |
|
irinotecan |
2.63 | 17725105 17287894 |
| MESH:D015179 |
Colorectal Neoplasms |
|
irinotecan |
2.36 | 15273666 17454858 18259882 16303861 17159606 18509181 16391804 |
| MESH:D003920 |
Diabetes Mellitus |
|
rosiglitazone |
10.39 | 17446233 |
| MESH:D003920 |
Diabetes Mellitus |
|
Sodium Selenite |
10.39 | 16285004 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
rosiglitazone |
2.99 | 12642470 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.70 | 17562736 15619225 19420014 15968718 18713872 16109766 11739529 16081117 11743745 12392966 19370779 10774834 16393943 19085960 12594235 11287661 16485898 11461765 19164858 12540782 2444490 16227642 19923254 16781746 10663392 17906064 11529661 10915739 11421492 17522070 12153990 16177239 19739265 12958197 12705907 14550746 14725611 18071297 11834606 14986274 19416960 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
6.70 | 15131321 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Sodium Selenite |
6.70 | 15131321 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.62 | 19426721 |
| MESH:D004487 |
Edema |
|
rosiglitazone |
3.97 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
rosiglitazone |
4.26 | 19196556 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.19 | 16983495 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.25 | 17162251 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
8.74 | 16870215 |
| MESH:D006930 |
Hyperalgesia |
|
rosiglitazone |
8.74 | 12083418 |
| MESH:D007249 |
Inflammation |
|
rosiglitazone |
3.26 | 12083418 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
4.72 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
rosiglitazone |
8.39 | 16306350 |
| MESH:D007333 |
Insulin Resistance |
|
Sodium Selenite |
8.39 | 14714311 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.36 | 12587719 15629191 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.21 | 16518626 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
rosiglitazone |
2.52 | 17347453 15980055 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 19460945 16610002 12969438 16611625 19014921 11587558 19784758 12587719 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.54 | 17185352 16871587 |
| MESH:D016393 |
Lymphoma, B-Cell |
|
Sodium Selenite |
4.41 | 14737004 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
rosiglitazone |
6.96 | 16827153 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
6.96 | 15318939 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.98 | 19513568 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.89 | 15107826 |
| MESH:D024821 |
Metabolic Syndrome X |
|
rosiglitazone |
4.64 | 17261469 |
| MESH:D052016 |
Mucositis |
|
irinotecan |
5.47 | 17159606 |
| MESH:D009362 |
Neoplasm Metastasis |
|
irinotecan |
3.27 | 18259882 |
| MESH:D009447 |
Neuroblastoma |
|
irinotecan |
3.62 | 8761367 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.14 | 18514411 |
| MESH:D017599 |
Neuroectodermal Tumors |
|
irinotecan |
5.19 | 8761367 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.65 | 16870215 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.41 | 15087411 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Sodium Selenite |
3.34 | 18760546 |
| MESH:D013274 |
Stomach Neoplasms |
|
irinotecan |
2.36 | 15723263 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.33 | 10982225 |
Related Pathway Information