Annotation Detail for DNASE1L2
Basic Information Top
| Gene Symbol: | DNASE1L2 ( DNAS1L2 ) |
|---|---|
| Gene Full Name: | deoxyribonuclease I-like 2 |
| Band: | 16p13.3 |
| Quick Links | Entrez ID:1775; OMIM: 602622; Uniprot ID:DNSL2_HUMAN; ENSEMBL ID: ENSG00000167968; HGNC ID: 2958 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of DNASE1L2 mRNA | affects expression | 17562736 |
| D002330 | Carmustine | Carmustine results in decreased expression of DNASE1L2 mRNA | decreases expression | 15980968 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001932 | Brain Neoplasms | Carmustine | 4.89 | 16187019 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 17906064 19164858 12705907 19370779 16781746 14550746 14725611 10663392 17522070 11287661 19416960 11529661 11421492 12392966 18071297 19739265 11461765 17562736 15968718 19923254 12958197 12540782 14986274 19420014 11834606 2444490 16227642 10915739 16109766 12153990 16177239 11739529 10774834 11743745 19085960 15619225 16081117 18713872 16393943 12594235 16485898 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D005909 | Glioblastoma | Carmustine | 4.22 | 16187019 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19460945 11587558 19784758 16611625 19014921 16610002 12969438 12587719 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 17185352 16871587 | |
| MESH:D008545 | Melanoma | Carmustine | 2.91 | 12393984 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D011471 | Prostatic Neoplasms | marker/mechanism | 17013881 | ||
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| No data |