AutismKB 2.0

Annotation Detail for DNMT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DNMT1 ( AIM,CXXC9,DNMT,FLJ16293,MCMT,MGC104992 )
Gene Full Name: DNA (cytosine-5-)-methyltransferase 1
Band: 19p13.2
Quick LinksEntrez ID:1786; OMIM: 126375; Uniprot ID:DNMT1_HUMAN; ENSEMBL ID: ENSG00000130816; HGNC ID: 2976
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa01100Metabolic pathways
hsa00270Cysteine and methionine metabolism
No data
Pathway IDPathway Name
200191Regulation of retinoblastoma protein
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of DNMT1 mRNAaffects expression 21346803
C067134 8-oxo-7-hydrodeoxyguanosine DNMT1 gene SNP affects the abundance of 8-oxo-7-hydrodeoxyguanosineaffects abundance 19896490
D000082 Acetaminophen Acetaminophen affects the expression of DNMT1 mRNAaffects expression 17562736
D019342 Acetic Acid Acetic Acid results in decreased expression of DNMT1 proteindecreases expression 17065238
D012435 S-Adenosylhomocysteine S-Adenosylhomocysteine results in decreased activity of DNMT1 proteindecreases activity 16037419
D006710 Homocysteine decitabine inhibits the reaction [Homocysteine results in decreased expression of DNMT1 protein]decreases expression|decreases reaction 18310117
D006710 Homocysteine decitabine inhibits the reaction [Homocysteine results in increased expression of DNMT1 mRNA]decreases reaction|increases expression 18310117
D006710 Homocysteine DNMT1 protein affects the reaction [Homocysteine results in decreased expression of CCNA1 mRNA]affects reaction|decreases expression 17698632
D006710 Homocysteine Folic Acid inhibits the reaction [Homocysteine results in decreased expression of DNMT1 protein]decreases expression|decreases reaction 18310117
D006710 Homocysteine Folic Acid inhibits the reaction [Homocysteine results in increased expression of DNMT1 mRNA]decreases reaction|increases expression 18310117
D006710 Homocysteine Homocysteine results in decreased activity of DNMT1 proteindecreases activity 17698632
D006710 Homocysteine trichostatin A inhibits the reaction [Homocysteine results in decreased expression of DNMT1 protein]decreases expression|decreases reaction 18310117
D006710 Homocysteine trichostatin A inhibits the reaction [Homocysteine results in increased expression of DNMT1 mRNA]decreases reaction|increases expression 18310117
D000639 Amitriptyline Amitriptyline results in decreased activity of DNMT1 proteindecreases activity 19924110
C006632 arsenic trioxide arsenic trioxide results in decreased expression of DNMT1 mRNAdecreases expression 17490527
C006632 arsenic trioxide arsenic trioxide results in decreased expression of DNMT1 proteindecreases expression 19679824
D001374 Azacitidine Azacitidine analog results in decreased expression of DNMT1 proteindecreases expression 17616700
D001374 Azacitidine Azacitidine results in decreased expression of DNMT1 mRNAdecreases expression 15547111
D001374 Azacitidine pifithrin inhibits the reaction [Azacitidine results in decreased expression of DNMT1 mRNA]decreases expression|decreases reaction 15547111
D001374 Azacitidine [SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 proteindecreases expression|increases uptake 19139132
D001374 Azacitidine TP53 protein promotes the reaction [Azacitidine results in decreased expression of DNMT1 mRNA]decreases expression|increases reaction 15547111
D001374 Azacitidine [Azacitidine co-treated with N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide] results in decreased expression of DNMT1 proteinaffects cotreatment|decreases expression 21224363
D001374 Azacitidine Azacitidine results in decreased expression of DNMT1 proteindecreases expression 21224363
D001564 Benzo(a)pyrene Benzo(a)pyrene inhibits the reaction [[DNMT1 protein binds to HDAC1 protein] which binds to CYP1A1 promoter]affects binding|decreases reaction 17682057
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinoline analog results in increased degradation of DNMT1 protein]decreases reaction|increases degradation 19417133
D001761 Bleomycin DNMT1 protein affects the susceptibility to Bleomycinaffects response to substance 17991895
D002392 Catechin Catechin results in decreased activity of DNMT1 proteindecreases activity 16037419
C023386 chlorinated dibenzofurans [Polychlorinated Biphenyls co-treated with polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in decreased expression of DNMT1 mRNAaffects cotreatment|decreases expression 15858227
D002794 Choline Choline affects the activity of DNMT1 proteinaffects activity 16855792
D002857 Chromium Chromium promotes the reaction [[DNMT1 protein binds to HDAC1 protein] which binds to CYP1A1 promoter]affects binding|increases reaction 17682057
C014347 decitabine [decitabine results in decreased activity of DNMT1 protein] which results in increased susceptibility to Cisplatindecreases activity|increases response to substance 18314485
C014347 decitabine decitabine inhibits the reaction [Homocysteine results in decreased expression of DNMT1 protein]decreases expression|decreases reaction 18310117
C014347 decitabine decitabine inhibits the reaction [Homocysteine results in increased expression of DNMT1 mRNA]decreases reaction|increases expression 18310117
C014347 decitabine decitabine results in decreased expression of DNMT1 mRNAdecreases expression 17621267
18676679
C014347 decitabine decitabine results in decreased expression of DNMT1 proteindecreases expression 19117987
19221000
18676679
17571247
17616700
17653094
17991895
19470736
C014347 decitabine decitabine results in increased degradation of DNMT1 proteinincreases degradation 19417133
C014347 decitabine decitabine results in increased expression of DNMT1 mRNAincreases expression 19117987
C014347 decitabine DNMT1 protein affects the reaction [decitabine results in increased expression of H2AFX protein]affects reaction|increases expression 17991895
C014347 decitabine DNMT1 protein affects the susceptibility to decitabineaffects response to substance 17991895
C014347 decitabine IL6 protein inhibits the reaction [decitabine results in decreased expression of DNMT1 mRNA]decreases expression|decreases reaction 17621267
C014347 decitabine decitabine results in decreased expression of DNMT1 proteindecreases expression 19222872
19679824
C014347 decitabine decitabine results in decreased activity of DNMT1 proteindecreases activity 19577553
D003997 Dicarbethoxydihydrocollidine Dicarbethoxydihydrocollidine results in increased expression of DNMT1 mRNAincreases expression 18098314
D002945 Cisplatin [decitabine results in decreased activity of DNMT1 protein] which results in increased susceptibility to Cisplatindecreases activity|increases response to substance 18314485
D002945 Cisplatin DNMT1 protein results in decreased susceptibility to Cisplatindecreases response to substance 18314485
D002945 Cisplatin DNMT1 protein results in decreased susceptibility to Cisplatindecreases response to substance 18314485
D004052 Diethylnitrosamine AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DNMT1 mRNA]decreases expression|decreases reaction 19996281
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of DNMT1 mRNAdecreases expression 19996281
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of DNMT1 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNMT1 mRNA]decreases reaction|increases expression 17854601
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of DNMT1 mRNAincreases expression 16714842
C007482 dimethyl sulfate dimethyl sulfate results in decreased expression of DNMT1 proteindecreases expression 11912126
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide results in decreased expression of DNMT1 proteindecreases expression 17065238
D004317 Doxorubicin DNMT1 protein affects the susceptibility to Doxorubicinaffects response to substance 17991895
D004317 Doxorubicin Doxorubicin inhibits the reaction [DNMT1 binds to RELN promoter]affects binding|decreases reaction 17065238
D004317 Doxorubicin [Doxorubicin inhibits the reaction [DNMT1 binds to RELN promoter]] which results in increased expression of RELN mRNAaffects binding|decreases reaction|increases expression 17065238
D004317 Doxorubicin Doxorubicin promotes the reaction [DNMT1 protein binds to BIRC5 promoter]affects binding|increases reaction 17124180
D004317 Doxorubicin Doxorubicin promotes the reaction [DNMT1 protein binds to CHEK1 protein]affects binding|increases reaction 17991895
D004317 Doxorubicin Doxorubicin results in decreased expression of and results in decreased activity of DNMT1 proteindecreases activity|decreases expression 17065238
C045651 epigallocatechin gallate epigallocatechin gallate binds to and results in decreased activity of DNMT1 proteinaffects binding|decreases activity 14633667
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased activity of DNMT1 proteindecreases activity 16037419
C045651 epigallocatechin gallate Magnesium promotes the reaction [epigallocatechin gallate results in decreased activity of DNMT1 protein]decreases activity|increases reaction 16037419
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of DNMT1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNMT1 mRNAaffects cotreatment|increases expression 17942748
D005047 Etoposide DNMT1 protein results in decreased susceptibility to Etoposidedecreases response to substance 18314485
D005047 Etoposide DNMT1 protein results in decreased susceptibility to Etoposidedecreases response to substance 18314485
C017875 fisetin [fisetin co-treated with COMT protein] results in decreased activity of DNMT1 proteinaffects cotreatment|decreases activity 16037419
D005492 Folic Acid Folic Acid affects the expression of DNMT1 mRNAaffects expression 17311948
D005492 Folic Acid Folic Acid inhibits the reaction [Homocysteine results in decreased expression of DNMT1 protein]decreases expression|decreases reaction 18310117
D005492 Folic Acid Folic Acid inhibits the reaction [Homocysteine results in increased expression of DNMT1 mRNA]decreases reaction|increases expression 18310117
D005492 Folic Acid Folic Acid affects the activity of DNMT1 proteinaffects activity 16855792
D019833 Genistein Genistein results in decreased expression of DNMT1 mRNAdecreases expression 16705744
D019833 Genistein Genistein results in decreased expression of DNMT1 proteindecreases expression 19221000
D006861 Hydrogen Peroxide DNMT1 protein results in decreased susceptibility to Hydrogen Peroxidedecreases response to substance 18314485
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of DNMT1 proteinincreases expression 18314485
D006861 Hydrogen Peroxide DNMT1 protein results in decreased susceptibility to Hydrogen Peroxidedecreases response to substance 18314485
D006918 Hydroxyurea DNMT1 protein affects the susceptibility to Hydroxyureaaffects response to substance 17991895
D008274 Magnesium Magnesium promotes the reaction [epigallocatechin gallate results in decreased activity of DNMT1 protein]decreases activity|increases reaction 16037419
D008274 Magnesium Magnesium results in decreased activity of DNMT1 proteindecreases activity 16037419
D008713 Methimazole Methimazole results in decreased expression of DNMT1 mRNAdecreases expression 17399805
D008741 Methyl Methanesulfonate Methyl Methanesulfonate results in decreased expression of DNMT1 proteindecreases expression 11912126
D008741 Methyl Methanesulfonate Methyl Methanesulfonate results in increased degradation of DNMT1 proteinincreases degradation 11912126
C020300 monomethylarsonic acid monomethylarsonic acid results in decreased expression of DNMT1 mRNAdecreases expression 17481689
C040015 myricetin [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 proteinaffects cotreatment|decreases activity 16037419
C040015 myricetin myricetin results in decreased activity of DNMT1 proteindecreases activity 16037419
C118739 N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide [Azacitidine co-treated with N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide] results in decreased expression of DNMT1 proteinaffects cotreatment|decreases expression 21224363
C508801 NSC 303530 NSC 303530 binds to DNMT1 proteinaffects binding 16420053
C508801 NSC 303530 NSC 303530 results in decreased activity of DNMT1 proteindecreases activity 16420053
C508802 NSC 401077 NSC 401077 binds to DNMT1 proteinaffects binding 16420053
C508802 NSC 401077 NSC 401077 results in decreased activity of DNMT1 proteindecreases activity 16420053
D010100 Oxygen Oxygen deficiency results in increased expression of DNMT1 proteinincreases expression 18314485
C494474 perchlorate perchlorate results in increased expression of DNMT1 mRNAincreases expression 17399805
D010634 Phenobarbital Phenobarbital affects the expression of DNMT1 mRNAaffects expression 19482888
C121565 pifithrin pifithrin inhibits the reaction [Azacitidine results in decreased expression of DNMT1 mRNA]decreases expression|decreases reaction 15547111
C006253 pirinixic acid pirinixic acid results in decreased expression of DNMT1 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in decreased expression of DNMT1 proteindecreases expression 18639561
D011078 Polychlorinated Biphenyls [Polychlorinated Biphenyls co-treated with polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in decreased expression of DNMT1 mRNAaffects cotreatment|decreases expression 15858227
C008954 polychlorodibenzo-4-dioxin [Polychlorinated Biphenyls co-treated with polychlorodibenzo-4-dioxin co-treated with chlorinated dibenzofurans] results in decreased expression of DNMT1 mRNAaffects cotreatment|decreases expression 15858227
D011441 Propylthiouracil Propylthiouracil results in increased expression of DNMT1 mRNAincreases expression 17399805
D011794 Quercetin [Quercetin co-treated with COMT protein] results in decreased activity of DNMT1 proteinaffects cotreatment|decreases activity 16037419
C037219 quinoline benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinoline analog results in increased degradation of DNMT1 protein]decreases reaction|increases degradation 19417133
C037219 quinoline quinoline analog results in increased degradation of DNMT1 proteinincreases degradation 19417133
C037219 quinoline quinoline analog results in decreased activity of DNMT1 proteindecreases activity 19417133
D012643 Selenium Selenium affects the activity of DNMT1 proteinaffects activity 16632891
C009277 sodium arsenate sodium arsenate results in decreased expression of DNMT1 mRNAdecreases expression 16882884
C017947 sodium arsenite sodium arsenite results in decreased expression of DNMT1 mRNAdecreases expression 17107663
C017947 sodium arsenite sodium arsenite affects the expression of DNMT1 mRNAaffects expression 17558810
C017947 sodium arsenite sodium arsenite results in increased expression of DNMT1 mRNAincreases expression 19822182
D018038 Sodium Selenite Sodium Selenite results in decreased expression of DNMT1 mRNAdecreases expression 18676679
D018038 Sodium Selenite Sodium Selenite results in decreased expression of DNMT1 proteindecreases expression 18676679
D013974 Thyroxine Thyroxine results in decreased expression of DNMT1 mRNAdecreases expression 17403546
D013974 Thyroxine Thyroxine results in increased expression of DNMT1 mRNAincreases expression 17403546
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNMT1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of DNMT1 mRNAdecreases expression 16611356
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DNMT1 mRNAincreases expression 15667827
D014212 Tretinoin Tretinoin results in decreased expression of DNMT1 mRNAdecreases expression 18230668
D014212 Tretinoin Tretinoin results in decreased expression of DNMT1 mRNAdecreases expression 17273765
C012589 trichostatin A trichostatin A inhibits the reaction [Homocysteine results in decreased expression of DNMT1 protein]decreases expression|decreases reaction 18310117
C012589 trichostatin A trichostatin A inhibits the reaction [Homocysteine results in increased expression of DNMT1 mRNA]decreases reaction|increases expression 18310117
C052920 trimethylarsine oxide trimethylarsine oxide results in decreased expression of DNMT1 mRNAdecreases expression 17481689
C025643 vinclozolin vinclozolin results in decreased expression of DNMT1 mRNAdecreases expression 18042343
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.276195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.2711752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3117505938
MESH:D058186 Acute Kidney Injury Cisplatin 11.5215814532 17670903 12690470
MESH:D058186 Acute Kidney Injury Folic Acid 11.5216316344 16595132 17003819
MESH:D058186 Acute Kidney Injury pifithrin 11.5217670903
MESH:D055371 Acute Lung Injury Bleomycin 12.1817118201
MESH:D055371 Acute Lung Injury Oxygen 12.1816759491
MESH:D055371 Acute Lung Injury pirinixic acid 12.1818653653
MESH:D000230 Adenocarcinoma marker/mechanism 17571247
MESH:D000230 Adenocarcinoma arsenic trioxide 14.4511798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 14.4520127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 14.4517638652 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 14.4517418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 14.4514692618
MESH:D000230 Adenocarcinoma Genistein 14.4511473722
MESH:D000236 Adenoma Benzo(a)pyrene 12.896695378
MESH:D000236 Adenoma Diethylnitrosamine 12.896695378 10737359
MESH:D000236 Adenoma Folic Acid 12.8916963246
MESH:D000236 Adenoma Magnesium 12.8917823441
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 19.8219061943 16434500 17620307 19052882 17162532 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 19.8217620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 19.8216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 19.8216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.2716712894 17306315
MESH:D000419 Albuminuria Doxorubicin 3.9621441931
MESH:D000505 Alopecia Tretinoin 3.1215955085
MESH:D000544 Alzheimer Disease Folic Acid 2.8917116317
MESH:D000686 Amyloidosis Diethylstilbestrol 3.8915469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.4111748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.6817084956
MESH:D000799 Angioedema Acetaminophen 3.2110982225
MESH:D000860 Anoxia Bleomycin 9.6115782499
MESH:D000860 Anoxia Oxygen 9.6120872349
MESH:D001008 Anxiety Disorders vinclozolin 3.1419015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.4719183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.8711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.8415885639
MESH:D001169 Arthritis, Experimental Tretinoin 5.8416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.0916292516
MESH:D001249 Asthma epigallocatechin gallate 4.4516516891
MESH:D001249 Asthma Tretinoin 4.4516456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.3615336622
MESH:D050197 Atherosclerosis Oxygen 3.4216391483
MESH:D001321 Autistic Disorder Acetaminophen 4.0418445737
MESH:D001321 Autistic Disorder Choline 4.0416818868
MESH:D001321 Autistic Disorder Folic Acid 4.0421388746
MESH:D001321 Autistic Disorder Homocysteine 4.0420468076 16297937
MESH:D001321 Autistic Disorder Magnesium 4.0416846101
MESH:D001321 Autistic Disorder S-Adenosylhomocysteine 4.0420468076 16917939
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 9.0819761891
MESH:D001327 Autoimmune Diseases Quercetin 9.0819761891
MESH:D001471 Barrett Esophagus Tretinoin 3.8116935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 22.9516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 22.9519483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 22.9519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 22.9512125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 22.9516206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3415746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 16.7414601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 16.7414601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 16.7414601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.2817150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 11.1820146248 17474063
MESH:D001943 Breast Neoplasms Chromium 11.1815986119
MESH:D001943 Breast Neoplasms Cisplatin 11.1818382427 19526202
MESH:D001943 Breast Neoplasms decitabine 11.1818320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 11.1817474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 11.1817129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 11.1818628466 17426702 15136595 15692762 16096432 16935488 19526202 15939500 16115903 15993339 11325840 18382427 15668708 16322301 16595493 17369602 15634643 15567936 18234424 15994142 16264153 18695136 16826403 17983394
MESH:D001943 Breast Neoplasms Etoposide 11.1816322251
MESH:D001943 Breast Neoplasms Folic Acid 11.1816777985
MESH:D001943 Breast Neoplasms Genistein 11.1817200150 16541309 16873071
MESH:D001943 Breast Neoplasms Oxygen 11.1817263869
MESH:D001943 Breast Neoplasms Quercetin 11.1818628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 11.1820435547
MESH:D001943 Breast Neoplasms Tretinoin 11.1816166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.9716813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7611589617
MESH:D002105 Cadmium Poisoning Quercetin 4.9216962696
MESH:D002276 Carcinoid Tumor Doxorubicin 4.1816051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.3116835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.5316168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 28.7716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 28.773084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 28.7715553829 16217749 14691202 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 28.7717982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 28.7719822196 18978308 18393292 16328049 18665156 16698587 19107877 16830150 20935162 20727157 16779866 16502159 19418558 20514400 17761372 16540662 3581430 18788625 20007298 19701751 19394651 20214788 11831363 16878318 18785209 18210153 10737359 16935385 17428255 16569478 20432363 18506893 19335982 17055752 20101231 17138121 18971187 19171122 19519916 10672840 18056438 3084413 19383236 17978847 20084675 19539802 17162532 19052882 20512989 17173139 18494052 16288022 16681979 19919837 20524982 19208518 18691550 21159647 16807293
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 28.7716924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 28.7716234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Genistein 28.7716924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 28.7717173139 6705139 20935162 1701930 20007298
MESH:D006528 Carcinoma, Hepatocellular Quercetin 28.7719519916 12508355
MESH:D006528 Carcinoma, Hepatocellular quinoline 28.77598648
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 28.7717306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 28.771917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.7912023789 16685392
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3517234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2419014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 2.8416201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5712490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 18.4920419170
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 18.496189445
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 18.4917066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell decitabine 18.4919215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 18.496189445
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 18.4918572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 18.4916096774 16051514
MESH:D006332 Cardiomegaly Quercetin 9.3719794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 9.3718670907 18850075 16120746
MESH:D006332 Cardiomegaly Thyroxine 9.3718093424
MESH:D009202 Cardiomyopathies Doxorubicin 3.1016731534 17308081 15811867 17329180 15792986 17131338 17928571 16269455 17382496 16651473 16952015 16364871 16612575 18627295 17974986 17519947 16278810 17351982 17007740 16242529 17924179 16455267 15505089 16109756 15476868
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7016243910 17334414
MESH:D002318 Cardiovascular Diseases Folic Acid 9.7416755160
MESH:D002318 Cardiovascular Diseases Genistein 9.7416332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 9.7416936243
MESH:D002386 Cataract Acetaminophen 5.9110977129
MESH:D002386 Cataract Tretinoin 5.9117460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 8.646135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 8.642727394 17174075 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 8.6420056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.654080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9716129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.5819052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.5816835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.1815861022 17681005 17110522 17333356 11677210 16105132 16919318
MESH:D002779 Cholestasis pirinixic acid 6.1819176532
MESH:D002822 Choriocarcinoma Tretinoin 4.5316461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.1515894690
MESH:D002971 Cleft Lip Folic Acid 3.6221254359
MESH:D002972 Cleft Palate Folic Acid 8.1421254359 8946559
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.148697196 15340226 16354765 15668235 12621046
MESH:D002972 Cleft Palate Tretinoin 8.149407595
MESH:D003092 Colitis Selenium 7.5017936198
MESH:D003092 Colitis Tretinoin 7.5017035595
MESH:D003110 Colonic Neoplasms decitabine 4.9817616700
MESH:D003110 Colonic Neoplasms Genistein 4.9817182828
MESH:D003110 Colonic Neoplasms Quercetin 4.9819056647 17148506 16640504 11134977 15741050 19440933 17191121
MESH:D003111 Colonic Polyps Magnesium 5.4717823441
MESH:D015179 Colorectal Neoplasms arsenic trioxide 13.3320501625
MESH:D015179 Colorectal Neoplasms Azacitidine 13.3319934284
MESH:D015179 Colorectal Neoplasms Cisplatin 13.3315273666
MESH:D015179 Colorectal Neoplasms decitabine 13.3318981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 13.3318802399 18259882
MESH:D015179 Colorectal Neoplasms Folic Acid 13.3317245555 16963246 17087956 16985020 17116713
MESH:D015179 Colorectal Neoplasms Magnesium 13.3317823441
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 13.3315531428
MESH:D015179 Colorectal Neoplasms Quercetin 13.3318852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5417141729 14669216
MESH:D003324 Coronary Artery Disease Homocysteine 3.5016379339
MESH:D023903 Coronary Restenosis arsenic trioxide 3.6012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.6510525206
MESH:D019465 Craniofacial Abnormalities sodium arsenate 4.6510525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.6515322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.6517551590 9211117 10589399 9664655 16925845 14991402 8800419 9224671 9125849 9142499
MESH:D003456 Cryptorchidism Diethylstilbestrol 9.4212952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 9.4214966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.4218551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.5215213294
MESH:D003704 Dementia marker/mechanism 21532572
MESH:D003704 Dementia Polychlorinated Biphenyls 4.1516140633
MESH:D003866 Depressive Disorder Amitriptyline 4.3918083778 15014590
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1118249437
MESH:D002658 Developmental Disabilities Choline 7.6216818868
MESH:D002658 Developmental Disabilities Magnesium 7.6216846101
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.2516285004
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.2319496084
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 11.5120387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 11.5116988119
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 11.5116886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 11.5116647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 11.5117107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 18.1218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 18.1217906064 14986274 11739529 11287661 14550746 14725611 10915739 16393943 11743745 11834606 12540782 16485898 11529661 19085960 2444490 17562736 19923254 11461765 12153990 12392966 15619225 16109766 12594235 11421492 18713872 19739265 19164858 15968718 10663392 12958197 10774834 16227642 19420014 19370779 17522070 19416960 16081117 18071297 12705907 16781746 16177239
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 18.1219107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 18.1217416283
MESH:D056486 Drug-Induced Liver Injury Selenium 18.1215131321
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 18.1218186108
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 18.1215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 18.1220420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4719426721
MESH:D004362 Drug Toxicity Cisplatin 11.0415033597 12649298 19839026 12231392
MESH:D004362 Drug Toxicity Doxorubicin 11.0418602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 11.0411462148
MESH:D004417 Dyspnea Oxygen 4.2120016425
MESH:D004421 Dystonia Phenobarbital 3.431851702
MESH:D004487 Edema Amitriptyline 12.0712798668
MESH:D004487 Edema Bleomycin 12.0717118201
MESH:D004487 Edema pirinixic acid 12.0712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 12.0712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.8515322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.8518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.6112538720
MESH:D004701 Endocrine Gland Neoplasms decitabine 11.9419294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 11.9419294695
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 5.9320641076
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.8416402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.8416402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 18.8515700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 18.8517359293
MESH:D016889 Endometrial Neoplasms Folic Acid 18.8517301261
MESH:D016889 Endometrial Neoplasms Genistein 18.8511473722
MESH:D016889 Endometrial Neoplasms Tretinoin 18.8516569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.499294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.5318037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.513659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.2511558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.5420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.026401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.657750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.403659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4916302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.1012903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.1016530937
MESH:D004938 Esophageal Neoplasms Cisplatin 6.1016481741 15464296 17638652 15173087 16785472
MESH:D017889 Exfoliation Syndrome Folic Acid 11.3416504073
MESH:D017889 Exfoliation Syndrome Homocysteine 11.3416504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.2611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.2616938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 14.2315073043
MESH:D005234 Fatty Liver Diethylnitrosamine 14.2320387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 14.2315345470
MESH:D005234 Fatty Liver pirinixic acid 14.2319236843 20131406
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.2515751030 16513791 16002989 16611131 16534752
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8611858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 3.9719069698
MESH:D005355 Fibrosis Quercetin 11.3619474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 11.3620067830
MESH:D005355 Fibrosis Tretinoin 11.3617994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6716904648
MESH:D005739 Gas Poisoning Oxygen 4.5920016425
MESH:D005756 Gastritis Acetaminophen 9.1916983495
MESH:D005756 Gastritis Folic Acid 9.1917171786
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.3216973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.6716417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.7616452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.7616452187
MESH:D005901 Glaucoma Folic Acid 9.9516504073
MESH:D005901 Glaucoma Homocysteine 9.9516504073
MESH:D005909 Glioblastoma Doxorubicin 22.2617150277
MESH:D005909 Glioblastoma Genistein 22.2616598420
MESH:D005909 Glioblastoma myricetin 22.2619804834
MESH:D005909 Glioblastoma Quercetin 22.2619804834
MESH:D005909 Glioblastoma Tretinoin 22.2617312396
MESH:D005909 Glioblastoma trichostatin A 22.2618801729
MESH:D005910 Glioma Quercetin 2.7817643826
MESH:D018149 Glucose Intolerance sodium arsenate 4.5119446573
MESH:D006042 Goiter perchlorate 4.7318801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9610696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 14.8815102660 15464296
MESH:D006258 Head and Neck Neoplasms decitabine 14.8819215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 14.8815692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 14.8816096774
MESH:D034381 Hearing Loss marker/mechanism 21532572
MESH:D034381 Hearing Loss Cisplatin 8.6419898482
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 8.6420641076
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.5316084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.9015464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 21.6420471113
MESH:D006330 Heart Defects, Congenital Folic Acid 21.6416524890 17286298
MESH:D006330 Heart Defects, Congenital Homocysteine 21.6419638421
MESH:D006330 Heart Defects, Congenital polychlorodibenzo-4-dioxin 21.6411294989
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 21.6410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 21.649664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 6.7416879835 18674790 17888722 16707910 16495754 12587719 18006777 16330681 14766674 16144979 17875725 16244372 16244371
MESH:D006331 Heart Diseases pifithrin 6.7414766674
MESH:D006333 Heart Failure Doxorubicin 9.4417481944
MESH:D006333 Heart Failure pirinixic acid 9.4420558911
MESH:D006333 Heart Failure Selenium 9.4417162251
MESH:D006390 Hemangioendothelioma quinoline 5.27598648
MESH:D006394 Hemangiosarcoma Doxorubicin 7.7915692506
MESH:D006394 Hemangiosarcoma quinoline 7.79598648
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7811000095
MESH:D006529 Hepatomegaly Phenobarbital 10.9216109766
MESH:D006529 Hepatomegaly pirinixic acid 10.9219176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.9212621046 16120746 15340226
MESH:D009477 Hereditary Sensory and Autonomic Neuropathies marker/mechanism 21532572
MESH:D006561 Herpes Simplex Etoposide 3.9510809021
MESH:D006679 HIV Seropositivity Folic Acid 4.8717209195
MESH:D006689 Hodgkin Disease Bleomycin 17.4518501091 15147373 17606976
MESH:D006689 Hodgkin Disease Cisplatin 17.4516170182 16200630
MESH:D006689 Hodgkin Disease Doxorubicin 17.4515147373 18501091 17606976
MESH:D006689 Hodgkin Disease Etoposide 17.4517606976 18180244 15147373 16135485 16200630
MESH:D006689 Hodgkin Disease sodium arsenite 17.4512676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4215340226 8697196 18606429 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 5.9816870215
MESH:D006930 Hyperalgesia Tretinoin 5.9816870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9616778211
MESH:D006943 Hyperglycemia pirinixic acid 7.4520558911
MESH:D006943 Hyperglycemia Quercetin 7.4511834736 18262572
MESH:D020138 Hyperhomocysteinemia Catechin 12.7517292331
MESH:D020138 Hyperhomocysteinemia Folic Acid 12.7516865747 16395265 16433478 16755160 16397167
MESH:D020138 Hyperhomocysteinemia Homocysteine 12.7517369066 18234410 17292331
MESH:D006965 Hyperplasia Diethylstilbestrol 3.8312960047 14722030
MESH:D006973 Hypertension Quercetin 4.3018356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.3018850075 18670907
MESH:D006980 Hyperthyroidism Methimazole 5.0314678291
MESH:D007021 Hypospadias Diethylstilbestrol 9.2416002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.2416569931 16945680
MESH:D007037 Hypothyroidism Methimazole 9.9518031379
MESH:D007037 Hypothyroidism Propylthiouracil 9.9518031379 8137927
MESH:D020244 Infarction, Middle Cerebral Artery pifithrin 5.0719475672
MESH:D007246 Infertility Diethylstilbestrol 3.7715036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8912013081
MESH:D007248 Infertility, Male decitabine 12.4917581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 12.4917937319
MESH:D007248 Infertility, Male sodium arsenite 12.4912646999 15346721
MESH:D007248 Infertility, Male vinclozolin 12.4916467254
MESH:D007249 Inflammation Amitriptyline 9.1612798668
MESH:D007249 Inflammation Bleomycin 9.1617118201
MESH:D007249 Inflammation Diethylnitrosamine 9.1618785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 9.1612878042 12200463
MESH:D007251 Influenza, Human Quercetin 8.9816624496
MESH:D007251 Influenza, Human Selenium 8.9816624496
MESH:D007333 Insulin Resistance pirinixic acid 5.8916306350
MESH:D007333 Insulin Resistance Sodium Selenite 5.8914714311
MESH:D007410 Intestinal Diseases Tretinoin 3.1717994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.0916580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.0917551590 15992940
MESH:D007627 Keloid Quercetin 4.3517086741
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.5115464296
MESH:D007674 Kidney Diseases Acetaminophen 18.8612587719 15629191
MESH:D007674 Kidney Diseases Chromium 18.8617934191
MESH:D007674 Kidney Diseases Cisplatin 18.8619839026 12649298 12231392 18289764 15190930
MESH:D007674 Kidney Diseases Doxorubicin 18.8615699352 16775033 15369732
MESH:D007674 Kidney Diseases Quercetin 18.8616962696
MESH:D007674 Kidney Diseases sodium arsenite 18.8620008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 13.5416707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 13.5416518626
MESH:D007676 Kidney Failure, Chronic Selenium 13.5416518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 5.8716705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 5.8716762066 15003126 14681315
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.1711231351
MESH:D007859 Learning Disorders Diethylstilbestrol 3.4617184923
MESH:D007938 Leukemia arsenic trioxide 20.1515070760
MESH:D007938 Leukemia Azacitidine 20.1519148494
MESH:D007938 Leukemia decitabine 20.1519235587 18980019
MESH:D007938 Leukemia Genistein 20.1517468513 18980019
MESH:D007938 Leukemia Quercetin 20.1517468513
MESH:D007938 Leukemia Tretinoin 20.1517143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.5316085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.2417077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.9614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 24.0419077051
MESH:D007951 Leukemia, Myeloid Azacitidine 24.0419077051
MESH:D007951 Leukemia, Myeloid decitabine 24.0419117987 17236224 18454857
MESH:D007951 Leukemia, Myeloid Hydroxyurea 24.0416532439
MESH:D007951 Leukemia, Myeloid Tretinoin 24.0416932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 10.0216968895 16467208 19850784 20471514 17050201
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 10.0217596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute decitabine 10.0218460780 19387464 17679729 18206229 19010910 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 10.0219850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 10.0218206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.8318055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.6219299654
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.2117869043 16891316 12018890 19225113 15622746 11161223 15748426 15213294 17217047 16966277 19035177 12679006 9834237 16823087 12712474 16330433 17107899 17649720 15336539 19075265 11468182 17712046 16112521 16331271 19642359
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.2112679006 17649720 19225113 17361223 17506722 19642359 19029980 16891316 19075265 17294898 17368321 17217047 16140955 17712046 16935935 16788101 17301526 19035177 16331271 17107899 15748426 9834237 16766008 16823087 17339181
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.7616882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.1116417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.859224671
MESH:D008064 Lipidoses Amitriptyline 4.4415342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.4018407596 18522880 20032147 18665156 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 5.4021047994
MESH:D008106 Liver Cirrhosis, Experimental Dicarbethoxydihydrocollidine 13.4716015684
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 13.4711682029
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 13.4716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 13.4717481882
MESH:D008106 Liver Cirrhosis, Experimental Genistein 13.4717823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 13.4715474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 13.4712741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 13.4712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 13.4718397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 7.6912969438 12587719 19460945 16611625 19014921 11587558 19784758 16610002
MESH:D008107 Liver Diseases Diethylnitrosamine 7.6917034775
MESH:D008107 Liver Diseases Folic Acid 7.6916877991
MESH:D008107 Liver Diseases Phenobarbital 7.6919363144
MESH:D017114 Liver Failure, Acute Acetaminophen 2.7017185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 28.227678174
MESH:D008113 Liver Neoplasms arsenic trioxide 28.2214682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 28.2221137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 28.2210737359 2862719 19427195 19255062 20452335 20583210 19812893 19996281 19256749 19294768 19642983 19254457 19833225 18754104 19850985 19499222 20501860 19638242 21071580 15175105 2422723 19426721 21167192 21278145 19551842 18648771 21047994 18644402 19090486 19690152 20492335 12112319 20434301 20101389 16942905 12771043 15885732 20137499 18978307 18977376 9163691 19073162 20118626 20405173
MESH:D008113 Liver Neoplasms Diethylstilbestrol 28.2216712894 15890375
MESH:D008113 Liver Neoplasms Phenobarbital 28.2219482888 19812893 19073162 8742319 21047994 15975961
MESH:D008113 Liver Neoplasms pirinixic acid 28.2220007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 28.2218980244
MESH:D008113 Liver Neoplasms sodium arsenite 28.2215276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 28.2216984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 26.052876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 26.0520377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 26.0516267830 19519916 19539802 16842330 19009564 9362446 18775883 18282651 17174075 18164116 18093689 18308698 2563599 19126423 17854601 17942915 18544905 18253720 18079962 3124819 19004024 21159647
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 26.0517085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 26.051399818 6150874 17172636 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 26.051423854
MESH:D008114 Liver Neoplasms, Experimental Quercetin 26.0519519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 26.0512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8715213294
MESH:D008171 Lung Diseases sodium arsenite 2.7419095001
MESH:D055370 Lung Injury Oxygen 3.9218339021
MESH:D008175 Lung Neoplasms marker/mechanism 21163286
MESH:D008175 Lung Neoplasms arsenic trioxide 17.8611798837 19825857
MESH:D008175 Lung Neoplasms Azacitidine 17.8621224363
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 17.8618569708 20064080 20464547 17053015 18816296 6695378 20135361 18520028 20869020
MESH:D008175 Lung Neoplasms Bleomycin 17.866189445
MESH:D008175 Lung Neoplasms Cisplatin 17.866189445 11798837 17225452
MESH:D008175 Lung Neoplasms Diethylnitrosamine 17.866695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Doxorubicin 17.8617418594 6189445
MESH:D008175 Lung Neoplasms N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide 17.8621224363
MESH:D008175 Lung Neoplasms Quercetin 17.8616280456
MESH:D008175 Lung Neoplasms sodium arsenite 17.8617077188 15276417 16712894 17306315 19931552
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 17.8619555203 11884234
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.1317718048
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.5315166399
MESH:D008223 Lymphoma decitabine 14.1819470736
MESH:D008223 Lymphoma Diethylstilbestrol 14.1815700306
MESH:D008223 Lymphoma Doxorubicin 14.1816098063
MESH:D008223 Lymphoma Etoposide 14.1812854902 12556972
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.4914737004
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.2817654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 3.9615621674
MESH:D008275 Magnesium Deficiency Magnesium 5.8317823441
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.8916002989
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 7.6315458769
MESH:D008325 Mammary Neoplasms, Experimental Genistein 7.6314578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Selenium 7.6315318939
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.0816832597
MESH:D008527 Medulloblastoma marker/mechanism 19155313
MESH:D008527 Medulloblastoma Tretinoin 2.5017453147
MESH:D008545 Melanoma Bleomycin 15.7415577320
MESH:D008545 Melanoma Cisplatin 15.7411135225 18332650 16248763 18176117 17023156 12393984 17761969 12883367 15577323 12374674 16809738 18505091 16432458
MESH:D008545 Melanoma decitabine 15.7416505122 17785578
MESH:D008545 Melanoma Doxorubicin 15.7416827129
MESH:D008545 Melanoma epigallocatechin gallate 15.7411746506 17992120
MESH:D008545 Melanoma sodium arsenite 15.7416487513 19082730
MESH:D008545 Melanoma Tretinoin 15.7416752155
MESH:D008545 Melanoma trichostatin A 15.7416505122
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.1615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9719513568
MESH:D008591 Meningomyelocele Homocysteine 10.4216602021
MESH:D008591 Meningomyelocele Tretinoin 10.4216940565
MESH:D001523 Mental Disorders Amitriptyline 4.2816856516
MESH:D008654 Mesothelioma Cisplatin 8.5817638057
MESH:D008654 Mesothelioma Doxorubicin 8.5817638057
MESH:D008654 Mesothelioma Selenium 8.5815107826
MESH:D008881 Migraine Disorders Amitriptyline 7.1918803445
MESH:D008881 Migraine Disorders Magnesium 7.1918803445
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9415792986
MESH:D009006 Monosomy Azacitidine 5.4519299654
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.7116381670
MESH:D052016 Mucositis Doxorubicin 4.1717415656
MESH:D009101 Multiple Myeloma arsenic trioxide 13.5919549372 19417148 15949261 14977855 11468182
MESH:D009101 Multiple Myeloma Azacitidine 13.5919549372 18443271
MESH:D009101 Multiple Myeloma decitabine 13.5918172295
MESH:D009101 Multiple Myeloma trichostatin A 13.5918172295
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 4.8717962980
MESH:D009135 Muscular Diseases pirinixic acid 2.9116239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.3018186108
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 14.4516105982 16882451
MESH:D009190 Myelodysplastic Syndromes Azacitidine 14.4519805378 17611569 18720364 17596541
MESH:D009190 Myelodysplastic Syndromes decitabine 14.4519010910 18608210 19157545 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 14.4517596541
MESH:D009203 Myocardial Infarction Doxorubicin 14.7115857846 19429709
MESH:D009203 Myocardial Infarction Genistein 14.7117141266
MESH:D009203 Myocardial Infarction Homocysteine 14.7117412321
MESH:D009203 Myocardial Infarction pirinixic acid 14.7119151258
MESH:D009203 Myocardial Infarction Quercetin 14.7119595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.5212213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 11.4317141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 11.4316411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 11.4319207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8617484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.2518551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.3716624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.033581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.0318259882
MESH:D009362 Neoplasm Metastasis quinoline 8.03598648
MESH:D009369 Neoplasms Benzo(a)pyrene 22.3511141357
MESH:D009369 Neoplasms Cisplatin 22.3516773208
MESH:D009369 Neoplasms decitabine 22.3519116145 19470736 17925555
MESH:D009369 Neoplasms Diethylstilbestrol 22.3515313581
MESH:D009369 Neoplasms pirinixic acid 22.3517405874
MESH:D009369 Neoplasms Quercetin 22.3515185748
MESH:D009369 Neoplasms sodium arsenite 22.3511559025
MESH:D009369 Neoplasms Tretinoin 22.3516946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.0720056578
MESH:D009395 Nephritis, Interstitial Cisplatin 3.8715464296
MESH:D009401 Nephrosis Doxorubicin 4.1716636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.4816889571 15640375
MESH:D009421 Nervous System Malformations Diethylstilbestrol 18.6611399458
MESH:D009421 Nervous System Malformations Genistein 18.6616427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.6614600291
MESH:D009421 Nervous System Malformations Tretinoin 18.669125849
MESH:D009436 Neural Tube Defects arsenic trioxide 18.2710525206
MESH:D009436 Neural Tube Defects Folic Acid 18.2717438019
MESH:D009436 Neural Tube Defects sodium arsenate 18.2711749123 18186108 19446573 10525206
MESH:D009436 Neural Tube Defects sodium arsenite 18.2712854658
MESH:D009436 Neural Tube Defects Tretinoin 18.279142499
MESH:D009447 Neuroblastoma Cisplatin 5.968761367
MESH:D009447 Neuroblastoma Doxorubicin 5.9615555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.4918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.4920387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.088761367
MESH:D020078 Neurogenic Inflammation Quercetin 3.7917929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4920387270
MESH:D009503 Neutropenia Folic Acid 3.9416322990
MESH:D009765 Obesity pirinixic acid 1.6420558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.9016049721
MESH:D010018 Osteomalacia Phenobarbital 3.7517016548
MESH:D010024 Osteoporosis Genistein 2.8519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.2416169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.2419495926
MESH:D012516 Osteosarcoma Doxorubicin 3.6115930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 22.8819769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 22.8815464296 19769630 6897625 17225452
MESH:D010051 Ovarian Neoplasms decitabine 22.8819259094 19331143
MESH:D010051 Ovarian Neoplasms Genistein 22.8819005980
MESH:D010051 Ovarian Neoplasms Quercetin 22.8819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 22.8815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 22.8816936753
MESH:D010051 Ovarian Neoplasms trichostatin A 22.8819331143
MESH:D010146 Pain Acetaminophen 8.5116870215
MESH:D010146 Pain Amitriptyline 8.5112798668
MESH:D010146 Pain Tretinoin 8.5116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 28.6915580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 28.6919003803
MESH:D010190 Pancreatic Neoplasms decitabine 28.6919294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 28.6916540662
MESH:D010190 Pancreatic Neoplasms Etoposide 28.6919003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 28.6916965848
MESH:D010190 Pancreatic Neoplasms Quercetin 28.6916965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 28.6915976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 28.6919294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1111578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.4912065085
MESH:D010235 Paraganglioma arsenic trioxide 3.5919927285
MESH:D010300 Parkinson Disease Homocysteine 5.1016275827
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 5.1016702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6212520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.7315464296
MESH:D003557 Phyllodes Tumor Doxorubicin 4.5317983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.5414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.0715687265 16977796
MESH:D010954 Plasmacytoma Selenium 4.2615087411
MESH:D010997 Pleural Neoplasms Cisplatin 11.8417638057
MESH:D010997 Pleural Neoplasms Doxorubicin 11.8417638057
MESH:D011014 Pneumonia Bleomycin 4.7916317386 18024389 17071938
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9718163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.342563599
MESH:D011230 Precancerous Conditions Phenobarbital 12.342563599
MESH:D011230 Precancerous Conditions Quercetin 12.3419056647
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 12.7217184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.7211222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 12.7219015723 18042343 18220299
MESH:D055728 Primary Myelofibrosis decitabine 10.4217616702
MESH:D055728 Primary Myelofibrosis trichostatin A 10.4217616702
MESH:D011350 Proctocolitis Acetic Acid 6.8011561086
MESH:D011469 Prostatic Diseases vinclozolin 4.3218220299
MESH:D011471 Prostatic Neoplasms arsenic trioxide 6.0919131511
MESH:D011471 Prostatic Neoplasms Azacitidine 6.0918324645
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 6.0917292933
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 6.0917136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Doxorubicin 6.0916868541 16729912 15749863 15897917 16888761 18437689
MESH:D011471 Prostatic Neoplasms Etoposide 6.0917172428
MESH:D011471 Prostatic Neoplasms fisetin 6.0918922931
MESH:D011471 Prostatic Neoplasms Genistein 6.0915256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide 6.0918798265
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 6.0915721890
MESH:D011471 Prostatic Neoplasms Quercetin 6.0914715546 17292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 6.0916039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 6.0918760546
MESH:D011471 Prostatic Neoplasms trichostatin A 6.0918798265 19789329
MESH:D011472 Prostatitis vinclozolin 4.3218629315
MESH:D011507 Proteinuria Tretinoin 3.0416636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.7015861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 3.8712752131
MESH:D011625 Pterygium Tretinoin 4.1716723453
MESH:D011654 Pulmonary Edema Bleomycin 4.6915808516
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.6015322207 11554783 18008008 16115399 17241526 16314464 17434272 12574379 14609568 18162602 17177178 15541506 21435439 12624602
MESH:D051437 Renal Insufficiency Cisplatin 13.7915464296
MESH:D051437 Renal Insufficiency Doxorubicin 13.7917922066
MESH:D051437 Renal Insufficiency Folic Acid 13.7915728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.0519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 3.9417627322 18339021
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2518990726
MESH:D012208 Rhabdomyosarcoma decitabine 9.0519155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.0516283617 16116481
MESH:D012509 Sarcoma Doxorubicin 3.4516767912 17710206 15625365 17203757 18313854 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 19.8316646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 19.8314601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 19.8316326096 14601052
MESH:D012512 Sarcoma, Ewing's Etoposide 19.8314601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.1717846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.9216862918
MESH:D012559 Schizophrenia Folic Acid 3.8516641680
MESH:D012559 Schizophrenia Homocysteine 3.8516641680
MESH:D012640 Seizures 2,6-dinitrotoluene 4.4918551238
MESH:D012640 Seizures Phenobarbital 4.493137016 11442880 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.206407741
MESH:D012871 Skin Diseases Folic Acid 5.1218709164
MESH:D012871 Skin Diseases monomethylarsonic acid 5.1221378128
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 18.1810029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 18.1815692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 18.1812065085
MESH:D012878 Skin Neoplasms sodium arsenite 18.1818572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 18.1816192470
MESH:D012878 Skin Neoplasms Tretinoin 18.1816467112
MESH:D007319 Sleep Initiation and Maintenance Disorders Amitriptyline 4.8315341891
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.7115464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.9617203757 15625365 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 9.6216709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 9.6216709447
MESH:D013118 Spinal Cord Diseases Folic Acid 4.8716361298
MESH:D016135 Spinal Dysraphism sodium arsenite 3.3112854658
MESH:D013274 Stomach Neoplasms marker/mechanism 17571247
MESH:D013274 Stomach Neoplasms arsenic trioxide 8.9717007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 8.9720155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 8.9715958060 17522103 18396642
MESH:D013274 Stomach Neoplasms decitabine 8.9719037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 8.9718456281
MESH:D013274 Stomach Neoplasms Folic Acid 8.9717171786
MESH:D013274 Stomach Neoplasms Tretinoin 8.9717261132
MESH:D013276 Stomach Ulcer Acetic Acid 4.7719188055
MESH:D020521 Stroke Folic Acid 3.8316517955
MESH:D013345 Subarachnoid Hemorrhage pifithrin 5.4318364113
MESH:D013398 Sudden Infant Death Oxygen 4.9312563064
MESH:D013736 Testicular Neoplasms Cisplatin 4.0617225452 15464296
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 10.2812697716
MESH:D013959 Thyroid Diseases Thyroxine 10.2819910387
MESH:D013964 Thyroid Neoplasms arsenic trioxide 26.4419014326
MESH:D013964 Thyroid Neoplasms decitabine 26.4417967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 26.447505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 26.4417909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 26.441399818
MESH:D013964 Thyroid Neoplasms Propylthiouracil 26.4415710170
MESH:D013964 Thyroid Neoplasms Tretinoin 26.4416026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.2516051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3515213294
MESH:D014376 Tuberculosis Tretinoin 2.8216040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 27.3516049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 27.3512973940 11780464 12845720 20435036
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 27.3517053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 27.3512973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms decitabine 27.3517616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 27.3516712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 27.3517653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 27.3516720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 27.3511723127 16452187 16712894 17306315
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.7010091137
MESH:D014581 Urticaria Acetaminophen 2.4110982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 18.2216803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 18.2216175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 18.2211813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 18.2216129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.5414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 7.5315809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.5314692618
MESH:D014604 Uveal Neoplasms decitabine 10.7417785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.7416752155
MESH:D014625 Vaginal Neoplasms Cisplatin 9.0815577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 9.0816002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 3.8117056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9612125929
MESH:D020301 Vasospasm, Intracranial pifithrin 5.0018364113
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9815869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.6216364871 17334414 17638931 17678736
MESH:D014820 Vitiligo Tretinoin 3.4716761959
MESH:D014839 Vomiting Cisplatin 4.0911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6215886252
MESH:D015431 Weight Loss Bleomycin 5.0312624602
MESH:D009396 Wilms Tumor Tretinoin 3.4416287080
Pathway ID Pathway Name
KEGG:00270 Cysteine and methionine metabolism
KEGG:01100 Metabolic pathways
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27443
    • No data
    Releated disease ID Related disease Name
    PA445062Neoplasms
    Releated drug ID Related drug Name
    PA451108procainamide
    PA451996azacitidine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00928 inhibitor Azacitidine Enzyme Inhibitors;Antimetabolites, Antineoplastic
    DB01035 other Procainamide Antiarrhythmic Agents;Anti-Arrhythmia Agents
    DB01099 other Flucytosine Antimetabolites;Antifungals;Antifungal Agents
    DB01262 antagonist Decitabine Antineoplastic Agents;Enzyme Inhibitors;Teratogens;Antimetabolites, Antineoplastic
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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