AutismKB 2.0

Annotation Detail for DRD1


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Basic Information Top
Gene Symbol:DRD1 ( DADR,DRD1A )
Gene Full Name: dopamine receptor D1
Band: 5q35.2
Quick LinksEntrez ID:1812; OMIM: 126449; Uniprot ID:DRD1_HUMAN; ENSEMBL ID: ENSG00000184845; HGNC ID: 3020
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
hsa04020Calcium signaling pathway
hsa04540Gap junction
Pathway IDPathway Name
Signaling by GPCR
No data
Pathway IDPathway Name
P00026Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00027Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
bipolar disorder
blood pressure, arterial
CARDIOVASCULAR
CHEMDEPENDENCY
ADHD
methamphetamine abuse psychoses
memory
bipolar disorder schizophrenia
PSYCH
alcoholism
attention-deficit hyperactivity disorder
Essential Hypertension
alcohol abuse
attention deficit hyperactivity disorder
schizophrenia
psychosis
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in increased expression of DRD1 mRNAincreases expression 19901195
C077358 7-benzylidenenaltrexone 7-benzylidenenaltrexone binds to and results in decreased activity of DRD1 proteinaffects binding|decreases activity 19482038
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY1 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY2 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY3 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY4 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY5 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY6 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY7 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY8 protein]affects binding|decreases reaction|increases activity 19922557
D002220 Carbamazepine Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY9 protein]affects binding|decreases reaction|increases activity 19922557
D003024 Clozapine Clozapine binds to DRD1 proteinaffects binding 11997696
D003024 Clozapine DRD1 gene polymorphism affects the susceptibility to Clozapineaffects response to substance 17092969
D003024 Clozapine DRD1 protein affects the susceptibility to Clozapineaffects response to substance 17092969
D003024 Clozapine Clozapine analog binds to DRD1 proteinaffects binding 11997696
D018818 Fenoldopam Fenoldopam binds to and results in increased activity of DRD1 proteinaffects binding|increases activity 19406658
D006220 Haloperidol Haloperidol binds to DRD1 proteinaffects binding 16983399
D008094 Lithium DRD1 gene polymorphism affects the susceptibility to Lithiumaffects response to substance 19153942
D008094 Lithium DRD1 protein results in increased susceptibility to Lithiumincreases response to substance 19153942
C534628 SCH 23390 SCH 23390 binds to and results in decreased activity of DRD1 proteinaffects binding|decreases activity 19482038
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY1 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY2 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY3 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY4 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY5 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY6 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY7 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY8 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 Carbamazepine inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY9 protein]affects binding|decreases reaction|increases activity 19922557
C071262 SK&F 82958 SK&F 82958 binds to and results in increased activity of DRD1 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY1 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY2 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY3 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY4 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY5 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY6 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY7 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY8 proteinaffects binding|increases activity 19922557
C071262 SK&F 82958 [SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased activity of ADCY9 proteinaffects binding|increases activity 19922557
C094142 TAN 67 TAN 67 binds to and results in increased activity of DRD1 proteinaffects binding|increases activity 19482038
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DRD1 mRNAincreases expression 19901195
D015647 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 proteinaffects binding|increases activity 15725338
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Carbamazepine 9.228986270
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 9.2215322242 11752688 14514962
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5316835633
MESH:D000380 Agranulocytosis Clozapine 5.1914617031 12649775 16160616
MESH:D000544 Alzheimer Disease Lithium 3.4819621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0511748828
MESH:D000855 Anorexia 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine 6.0112183048
MESH:D001321 Autistic Disorder marker/mechanism 18205172
MESH:D001321 Autistic Disorder Haloperidol 2.7319368416 18080171
MESH:D001714 Bipolar Disorder marker/mechanism 19153942
MESH:D001714 Bipolar Disorder Carbamazepine 8.1820046352 17594078
MESH:D001714 Bipolar Disorder Lithium 8.1817594078 20046352 20338123 19153942
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.1512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8315746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.7020435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4216120746 18670907 18850075
MESH:D002375 Catalepsy Haloperidol 5.0615215559 1977408
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2616835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1412621046 15668235 16354765 8697196 15340226
MESH:D003072 Cognition Disorders Clozapine 5.1017123785
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1617141729 14669216
MESH:D019465 Craniofacial Abnormalities Carbamazepine 2.899014606
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.8920055451 15322242 10048152
MESH:D007644 Darier Disease Lithium 6.0620338123
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.9620210726
MESH:D003704 Dementia Haloperidol 4.6911575062
MESH:D018500 Diabetes Insipidus, Nephrogenic Lithium 5.8819244398
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 4.5916402076
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.5917107852
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.7315331141
OMIM:607208 DRAVET SYNDROME Carbamazepine 5.5811748493
MESH:D004342 Drug Hypersensitivity Carbamazepine 4.4716538176 20216337 15057820 16538175
MESH:D056486 Drug-Induced Liver Injury Carbamazepine 4.2617465707
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.2620420201
MESH:D004362 Drug Toxicity Carbamazepine 8.6720216337
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.6711462148
MESH:D050171 Dyslipidemias Clozapine 4.2616402076
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.0818230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Carbamazepine 4.8617654737
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 4.1919148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.129294722 10568697
MESH:D004816 Epidermal Necrolysis, Toxic Carbamazepine 5.3819915237 18855540 16538176 20485159 16415921
MESH:D004831 Epilepsies, Myoclonic Carbamazepine 5.3517275665
MESH:D004828 Epilepsies, Partial Carbamazepine 5.1515008574 16628512 17116037
MESH:D004827 Epilepsy Carbamazepine 4.047988514 9014606 18234410 19620853 20417680 17465707 17178248 19700373 19439326 821787
MESH:D017029 Epilepsy, Complex Partial Carbamazepine 5.497750514
MESH:D004830 Epilepsy, Tonic-Clonic Carbamazepine 5.2715276670 3659116
MESH:D004916 Erythromelalgia Carbamazepine 5.8819549232
MESH:D005076 Exanthema Carbamazepine 5.6220485159
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0911564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5911858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.0920067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7710696789
MESH:D006330 Heart Defects, Congenital Lithium 7.2019638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.2011294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4411000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0315340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.2215340226 18606429 16354765 16959395 8697196
MESH:D020138 Hyperhomocysteinemia Carbamazepine 4.8210459572
MESH:D006948 Hyperkinesis Clozapine 5.0616046005
MESH:D006965 Hyperplasia Carbamazepine 5.3518773962
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9418670907 18850075
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9112878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.4416580747
MESH:D008064 Lipidoses Clozapine 4.0417567588
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.7516984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.1712151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D008180 Lupus Erythematosus, Systemic Carbamazepine 3.5916628512
MESH:D001523 Mental Disorders Clozapine 8.8816856516
MESH:D001523 Mental Disorders Haloperidol 8.8816856516
MESH:D008607 Mental Retardation Carbamazepine 3.769014606
MESH:D024821 Metabolic Syndrome X Clozapine 4.5019142101
MESH:D009203 Myocardial Infarction Lithium 3.9616288908
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1112213967
MESH:D009224 Myotonia Congenita Carbamazepine 5.6220399394
MESH:D009421 Nervous System Malformations Carbamazepine 10.3616990009
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.3614600291
MESH:D009765 Obesity Clozapine 3.0419142110 18515891
MESH:D010018 Osteomalacia Carbamazepine 5.6217016548
MESH:D010146 Pain Carbamazepine 4.1215215642
MESH:D010267 Parapsoriasis Carbamazepine 5.8416538176
OMIM:167400 PAROXYSMAL EXTREME PAIN DISORDER Carbamazepine 6.0817145499 17679678
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6918163543
MESH:D011248 Pregnancy Complications Carbamazepine 5.299014606
MESH:D011297 Prenatal Exposure Delayed Effects Carbamazepine 10.379014606
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 10.3711896295 11118676 11399792 11222880
MESH:D019310 Pseudolymphoma Carbamazepine 5.7712752131 9591791
MESH:D011595 Psychomotor Agitation Haloperidol 5.0911575062
MESH:D011618 Psychotic Disorders Clozapine 9.4215331141
MESH:D011618 Psychotic Disorders Haloperidol 9.4211575062
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9618990726
MESH:D012559 Schizophrenia marker/mechanism 18583979
MESH:D012559 Schizophrenia Clozapine 4.1518806925 20521326 20521320 20107430 11151749 20452607 20168265 18855531 20580759 17726453 16141801 11763009 17123785 17667964 19369910
MESH:D012559 Schizophrenia Haloperidol 4.1520107430 19369910 1830565 18513383
MESH:D012640 Seizures Carbamazepine 7.1115946322 9046859 16180713 16938433 19414003 9844417 16876388
MESH:D012640 Seizures Lithium 7.1119660546
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0916192470
MESH:D012893 Sleep Disorders Carbamazepine 5.2719414003
MESH:D013226 Status Epilepticus Lithium 5.9619951488 19570321 19430551
MESH:D013262 Stevens-Johnson Syndrome Carbamazepine 5.3519694795 15057820 16415921 16538176 18855540 20485159 19915237
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.8320210726
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0812697716
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7712125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4215886252
MESH:D015430 Weight Gain Clozapine 4.5716402076 20564506 20521320 16141801 20107430 17502770
MESH:D015431 Weight Loss Clozapine 5.2317933447
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:04540 Gap junction
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA147
    • Releated gene ID Related gene Name
    PA43AGTR1
    Releated disease ID Related disease Name
    PA446876Substance-Related Disorders
    PA128406954Weight gain
    PA447208Mental Disorders
    PA447216Schizophrenia
    Releated drug ID Related drug Name
    PA452233antipsychotics
    PA450688olanzapine
    PA164743471adenosine triphosphate
    PA449396dopamine
    PA449072cocaine
    PA449061clozapine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00246 antagonist Ziprasidone Antipsychotics;Dopamine Antagonists;Serotonin Antagonists;Antipsychotic Agents
    DB00248 agonist Cabergoline Antineoplastic Agents;Antiparkinson Agents;Dopamine Agonists
    DB00268 agonist Ropinirole Central Nervous System Agents;Antiparkinson Agents;Antidyskinetics;Dopamine Agonists
    DB00334 antagonist Olanzapine Antiemetics;Antipsychotics;Antipsychotic Agents;Serotonin Uptake Inhibitors
    DB00353 antagonist Methylergonovine Oxytocics
    DB00363 antagonist Clozapine Antipsychotics;Serotonin Antagonists;Antipsychotic Agents;GABA Antagonists
    DB00372 antagonist Thiethylperazine Antiemetics;Dopamine Antagonists;Anti-emetics
    DB00397 partial agonist Tussaminic DH Pediatric Syrup Sympathomimetics;Appetite Depressants;Adrenergic alpha-Agonists;Nasal Decongestants
    DB00408 antagonist Loxapine Antipsychotics;Dopamine Antagonists;Antipsychotic Agents
    DB00413 unknown Pramipexole Antioxidants;Free Radical Scavengers;Antiparkinson Agents;Antidyskinetics;Dopamine Agonists
    DB00420 antagonist Promazine Antiemetics;Antipsychotics;Dopamine Antagonists;Neuroleptics;Phenothiazines;Antipsychotic Agents
    DB00477 antagonist Chlorpromazine Antiemetics;Antipsychotics;Dopamine Antagonists;Phenothiazines;Antipsychotic Agents
    DB00502 antagonist Haloperidol Antiemetics;Antidyskinetics;Antipsychotics;Dopamine Antagonists;Antipsychotic Agents;Butyrophenones;Anti-Dyskinesia Agents
    DB00508 antagonist Triflupromazine Antiemetics;Antipsychotics;Dopamine Antagonists;Antipsychotic Agents
    DB00543 antagonist Amoxapine Adrenergic Uptake Inhibitors;Dopamine Antagonists;Serotonin Uptake Inhibitors;Antidepressive Agents, Second-Generation;Neurotransmitter Uptake Inhibitors
    DB00589 antagonist Lisuride Antiparkinson Agents;Antidyskinetics;Dopamine Agonists;Serotonin Agonists
    DB00623 antagonist Fluphenazine Antipsychotics;Dopamine Antagonists;Phenothiazines;Antipsychotic Agents
    DB00679 antagonist Thioridazine Antipsychotics;Dopamine Antagonists;Phenothiazines;Antipsychotic Agents
    DB00714 agonist Homeopathic Remedy Thc No. 48 Dps Antiparkinson Agents;Antidyskinetics;Dopamine Agonists
    DB00726 other/unknown Trimipramine Antidepressants;Adrenergic Uptake Inhibitors;Antidepressive Agents, Tricyclic;Norepinephrine-Reuptake Inhibitors
    DB00734 antagonist Risperidone Antipsychotics;Dopamine Antagonists;Serotonin Antagonists;Antipsychotic Agents
    DB00777 antagonist Propiomazine Sedatives and Hypnotics
    DB00800 agonist Fenoldopam Antihypertensive Agents;Vasodilator Agents;Dopamine Agonists
    DB00805 agonist Minaprine Central Nervous System Agents;Antiparkinson Agents;Antidepressive Agents
    DB00850 antagonist Triavil Tab Antipsychotics;Dopamine Antagonists;Phenothiazines;Antipsychotic Agents
    DB00875 antagonist Flupenthixol Antipsychotics;Dopamine Antagonists;Antipsychotic Agents;Thioxanthenes
    DB00988 agonist Dopamine Dopamine Agents;Sympathomimetics;Cardiotonic Agents;Sympathomimetic
    DB01038 antagonist Carphenazine Antipsychotics
    DB01063 antagonist Acetophenazine Antipsychotics
    DB01186 agonist Pergolide Central Nervous System Agents;Antiparkinson Agents;Antidyskinetics;Dopamine Agonists;Neuroprotective Agents
    DB01200 agonist Bromocriptine Antiparkinson Agents;Antidyskinetics;Dopamine Agonists;Hormone Antagonists
    DB01224 antagonist Quetiapine Antipsychotics;Antipsychotic Agents
    DB01235 agonist Sinemet CR Dopamine Agents;Antiparkinson Agents;Antidyskinetics
    DB01238 partial agonist Aripiprazole Antipsychotics;Antipsychotic Agents
    DB01239 antagonist Chlorprothixene Antipsychotics;Dopamine Antagonists;Antipsychotic Agents
    DB01267 antagonist Paliperidone Antipsychotic Agents
    DB01287 agonist Dihydroergotoxine
    DB01403 antagonist Methotrimeprazine Dopamine Antagonists;Analgesics, Non-Narcotic;Antipsychotic Agents
    DB01608 other/unknown Propericiazine Phenothiazines;Antipsychotic Agents
    DB01614 antagonist Acepromazine Dopamine Antagonists;Antipsychotic Agents;Sedatives and Hypnotics
    DB01621 antagonist Pipotiazine Phenothiazines;Antipsychotic Agents
    DB01622 antagonist Thioproperazine Phenothiazines;Antipsychotic Agents
    DB01623 antagonist Thiothixene Dopamine Antagonists;Antipsychotic Agents;Thioxanthenes
    DB01624 antagonist Zuclopenthixol Dopamine Antagonists;Antipsychotic Agents
    DB05271 agonist Rotigotine Transdermal Patch Antiparkinson Agents;Antidyskinetics;Dopamine Agonists
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    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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