AutismKB 2.0

Annotation Detail for ECM2


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Basic Information Top
Gene Symbol:ECM2 ( MGC126355,MGC126356 )
Gene Full Name: extracellular matrix protein 2, female organ and adipocyte specific
Band: 9q22.31
Quick LinksEntrez ID:1842; OMIM: 603479; Uniprot ID:ECM2_HUMAN; ENSEMBL ID: ENSG00000106823; HGNC ID: 3154
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ECM2 proteinaffects expression 20106945
D002330 Carmustine Carmustine results in increased expression of ECM2 mRNAincreases expression 15980968
D016572 Cyclosporine Cyclosporine results in decreased expression of ECM2 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of ECM2 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ECM2 mRNAdecreases expression 17557909
C008493 methylselenic acid methylselenic acid results in increased expression of ECM2 mRNAincreases expression 18548127
C041786 palm oil palm oil results in increased expression of ECM2 mRNAincreases expression 18042831
D012643 Selenium Selenium results in decreased expression of ECM2 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3217505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D001161 Arteriosclerosis Dietary Fats 10.9515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 10.9511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8015885639
MESH:D001932 Brain Neoplasms Carmustine 4.6116187019
MESH:D001943 Breast Neoplasms Dietary Fats 2.2620435547
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 1.9821507988 12907637 12619106
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.6812371664
MESH:D002779 Cholestasis Cyclosporine 8.3719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.3717681005 17333356 16919318 17110522 16105132 11677210 15861022
MESH:D003092 Colitis Selenium 4.0917936198
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2315131321
MESH:D050171 Dyslipidemias Dietary Fats 3.6218367378
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4712538720
MESH:D005234 Fatty Liver Cyclosporine 14.5219224547
MESH:D005234 Fatty Liver Dietary Fats 14.5218296743 19004024 17967931 19551842
MESH:D005234 Fatty Liver Ethinyl Estradiol 14.5215345470
MESH:D005355 Fibrosis Cyclosporine 9.7312168785 12639820
MESH:D005355 Fibrosis Dietary Fats 9.7318296743
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.568708960
MESH:D005909 Glioblastoma Carmustine 4.0716187019
MESH:D006333 Heart Failure Selenium 3.2117162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.7615720958
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8321332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.8721332399
MESH:D006973 Hypertension Cyclosporine 2.1710903974
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1216945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6417937319
MESH:D007249 Inflammation Dietary Fats 2.5420412841
MESH:D007251 Influenza, Human Selenium 4.5716624496
MESH:D007333 Insulin Resistance Dietary Fats 3.2511836018 18457598
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8215604871
MESH:D007674 Kidney Diseases Cyclosporine 2.468314463 10903974 18776723
MESH:D007676 Kidney Failure, Chronic Selenium 4.1316518626
MESH:D007680 Kidney Neoplasms Cyclosporine 2.9312371664
MESH:D008103 Liver Cirrhosis Dietary Fats 2.9918296743
MESH:D008113 Liver Neoplasms Aflatoxin B1 2.422125692 15890375 9163691 18177683
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.888603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 1.8714755239
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9015318939
MESH:D008545 Melanoma Carmustine 2.8912393984
MESH:D008654 Mesothelioma Selenium 2.8715107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.1616801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5018481113 19348381
MESH:D009765 Obesity Dietary Fats 2.3321332399 18674790 17217161 20132043 18457598 19632207 16723640 20518802 11836018
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9511578682
MESH:D010954 Plasmacytoma Selenium 5.2715087411
MESH:D011230 Precancerous Conditions Cyclosporine 3.4412371664
MESH:D011471 Prostatic Neoplasms methylselenic acid 3.8516205645
MESH:D011537 Pruritus Ethinyl Estradiol 3.6516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D013088 Spermatocele Ethinyl Estradiol 4.3216709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3715669648
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5814692618
MESH:D014605 Uveitis Cyclosporine 4.361336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7814671159 15869587
MESH:D015430 Weight Gain Dietary Fats 3.9516723640
MESH:D014985 Xerophthalmia Cyclosporine 4.8217120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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