AutismKB 2.0

Annotation Detail for DUSP5


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Basic Information Top
Gene Symbol:DUSP5 ( DUSP,HVH3 )
Gene Full Name: dual specificity phosphatase 5
Band: 10q25.2
Quick LinksEntrez ID:1847; OMIM: 603069; Uniprot ID:DUS5_HUMAN; ENSEMBL ID: ENSG00000138166; HGNC ID: 3071
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
No data
Pathway IDPathway Name
200116ATF-2 transcription factor network
200101Direct p53 effectors
Pathway IDPathway Name
P00046Oxidative stress response
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of DUSP5 mRNAdecreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of DUSP5 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen results in increased expression of DUSP5 mRNAincreases expression 17202762
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of DUSP5 proteinaffects expression 20106945
C011512 alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]affects cotreatment|decreases expression|decreases reaction 19578757
C011512 alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein]affects cotreatment|decreases expression|decreases reaction 19578757
D000643 Ammonium Chloride Ammonium Chloride affects the expression of DUSP5 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of DUSP5 mRNAdecreases expression 20016248
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of DUSP5 mRNAincreases expression 18687144
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DUSP5 mRNAdecreases expression 20382639
C095105 bexarotene bexarotene results in decreased expression of DUSP5 mRNAdecreases expression 17178900
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of DUSP5 mRNAincreases expression 15912405
C006780 bisphenol A bisphenol A affects the expression of DUSP5 mRNAaffects expression 20170705
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of DUSP5 mRNAincreases expression 17553608
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of DUSP5 mRNAincreases expression 15336504
D003474 Curcumin Curcumin results in increased expression of DUSP5 mRNAincreases expression 17198877
D016572 Cyclosporine Cyclosporine results in increased expression of DUSP5 mRNAincreases expression 20106945
D002117 Calcitriol Calcitriol results in increased expression of DUSP5 mRNAincreases expression 16002434
D004391 Dust Dust results in increased expression of DUSP5 mRNAincreases expression 17805423
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of DUSP5 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of DUSP5 mRNAincreases expression 19619570
20106945
19153601
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of DUSP5 mRNAaffects expression 20170705
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of DUSP5 mRNAaffects expression 20170705
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in increased expression of DUSP5 mRNA]affects reaction|increases expression 15016801
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of DUSP5increases expression 18687144
C475919 hydroxytamoxifen GPR30 protein affects the reaction [hydroxytamoxifen results in increased expression of DUSP5 mRNA]affects reaction|increases expression 19153601
C475919 hydroxytamoxifen hydroxytamoxifen results in increased expression of DUSP5 mRNAincreases expression 19153601
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of DUSP5 mRNAincreases expression 17412507
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased expression of DUSP5 mRNAincreases expression 16809437
C029938 nickel sulfate nickel sulfate results in increased expression of DUSP5 mRNAincreases expression 16780908
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of DUSP5 mRNAincreases expression 17616710
D010100 Oxygen alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]affects cotreatment|decreases expression|decreases reaction 19578757
D010100 Oxygen alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein]affects cotreatment|decreases expression|decreases reaction 19578757
D010100 Oxygen [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNAaffects cotreatment|decreases expression 19578757
D010100 Oxygen [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 proteinaffects cotreatment|decreases expression 19578757
D010126 Ozone Ozone results in increased expression of DUSP5 mRNAincreases expression 16716893
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of DUSP5 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of DUSP5 mRNAaffects binding|increases activity|increases expression 19710929
D011374 Progesterone Progesterone results in increased expression of DUSP5 mRNAincreases expression 18037150
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in increased expression of DUSP5 mRNAaffects cotreatment|increases expression 19059307
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in increased expression of DUSP5 mRNAaffects cotreatment|increases expression 19059307
C021751 tanshinone tanshinone results in increased expression of DUSP5 mRNAincreases expression 15849732
D013749 Tetrachlorodibenzodioxin alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNA]affects cotreatment|decreases expression|decreases reaction 19578757
D013749 Tetrachlorodibenzodioxin alpha-naphthoflavone inhibits the reaction [[Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 protein]affects cotreatment|decreases expression|decreases reaction 19578757
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of DUSP5 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 mRNAaffects cotreatment|decreases expression 19578757
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased expression of DUSP5 proteinaffects cotreatment|decreases expression 19578757
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of DUSP5 mRNAdecreases expression 12377990
19619570
20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of DUSP5 mRNAdecreases expression 19933214
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of DUSP5 mRNA]decreases reaction|increases expression 19225232
C034028 vanadyl sulfate vanadyl sulfate results in increased expression of DUSP5 mRNAincreases expression 16330358
D015032 Zinc Zinc results in decreased expression of DUSP5 mRNAdecreases expression 17074742
D019287 Zinc Sulfate Zinc Sulfate results in decreased expression of DUSP5 mRNAdecreases expression 17074742
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1314745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.4515322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 9.2718287403
MESH:D000138 Acidosis Zinc Sulfate 9.277265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5317505938
MESH:D000169 Acrodermatitis Zinc 5.0017202136 17190629 16889938
MESH:D055371 Acute Lung Injury nickel sulfate 13.2312718980 16100012 19131640 11954676
MESH:D055371 Acute Lung Injury Oxygen 13.2316759491
MESH:D055371 Acute Lung Injury pirinixic acid 13.2318653653
MESH:D000230 Adenocarcinoma arsenic trioxide 12.2911798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 12.2911473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.2914692618
MESH:D000230 Adenocarcinoma Fluorouracil 12.2917638652
MESH:D000230 Adenocarcinoma Methylnitrosourea 12.2915688392 15113128
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.5516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.5516835633
MESH:D000419 Albuminuria Raloxifene 4.2117308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 4.6717887948
MESH:D000544 Alzheimer Disease Curcumin 8.6015590663
MESH:D000544 Alzheimer Disease Ozone 8.6015513908
MESH:D000544 Alzheimer Disease Raloxifene 8.6015800139
MESH:D000544 Alzheimer Disease Zinc 8.6016325427 16580781 17119284 16410023
MESH:D000740 Anemia Fluorouracil 7.5116511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.5111748828
MESH:D000755 Anemia, Sickle Cell Zinc 4.5116916123
MESH:D000799 Angioedema Acetaminophen 3.4310982225
MESH:D000860 Anoxia Oxygen 10.1620872349
MESH:D000860 Anoxia Zinc Sulfate 10.167265320
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.0711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.4115885639
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.4716807698
MESH:D001172 Arthritis, Rheumatoid Ozone 4.4715570426
MESH:D001249 Asthma Ozone 4.7216373670 17854713
MESH:D001249 Asthma Zinc 4.7217085522
MESH:D050197 Atherosclerosis Curcumin 6.2918704882
MESH:D050197 Atherosclerosis Oxygen 6.2916391483
MESH:D001321 Autistic Disorder Acetaminophen 1.4618445737
MESH:D001327 Autoimmune Diseases Curcumin 4.1019761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.1816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.1819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.1812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5015746008
MESH:D001862 Bone Resorption bisphenol A 3.5011985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9217868700
MESH:D001930 Brain Injuries Progesterone 16.1615665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 16.1616580743
MESH:D001930 Brain Injuries Zinc 16.1617109824
MESH:D002545 Brain Ischemia Curcumin 3.9316770732
MESH:D001932 Brain Neoplasms Curcumin 3.5917596214
MESH:D001943 Breast Neoplasms bexarotene 10.4516344269 16818667
MESH:D001943 Breast Neoplasms bisphenol A 10.4517123778
MESH:D001943 Breast Neoplasms Calcitriol 10.4511237771
MESH:D001943 Breast Neoplasms Curcumin 10.4518462866 18593918 16243823 19250217
MESH:D001943 Breast Neoplasms Estradiol 10.4517289903 17261762 12948864 17018787 14630087 19861407 18497071 16675129
MESH:D001943 Breast Neoplasms Fluorouracil 10.4515136595 16110121 19217205 16557594 18608205 18357371 16595493
MESH:D001943 Breast Neoplasms Methylnitrosourea 10.4516253758 11306469 14633655
MESH:D001943 Breast Neoplasms Oxygen 10.4517263869
MESH:D001943 Breast Neoplasms Progesterone 10.4516175315 15562024 17614352
MESH:D001943 Breast Neoplasms Raloxifene 10.4517049068 15572757 17242785 17261762 16837676 15758505 15775269 17893378 17595753 17952589 17440819 16912660
MESH:D001943 Breast Neoplasms Tamoxifen 10.4511161223 16273361 18855134 19487384 19115204 19200415 18815881 21138602 19221464 18821012 19011961 19103187 17893378 17049068 20135344 20065188 18629630 19410462 15565566 16818667 19142967 20390343 15668708 17440819 16202921 18984771 20544844 20005174 19289846 19189212 18351453 19084267 19155303 19244106 18425577 21152245 19066611 20859285 19189210 19059307 18997820 16873071 17261762 17242785 19288272
MESH:D001943 Breast Neoplasms tanshinone 10.4519885617 15849732
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.4520435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3615516495 17626835 18315731 16777450 18417511 14754758 19059883
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9511589617
MESH:D002100 Cachexia Ozone 4.3316183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0616111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.2516051944
MESH:D002277 Carcinoma Curcumin 12.1218593918
MESH:D002277 Carcinoma Fluorouracil 12.1217121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 12.1216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1119066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 12.8816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 12.883084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 12.8821507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 12.8815553829 16217749 11135700 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Estradiol 12.8816924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 12.8817088986 17045692 17971768 16332177 18930000 16799960
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 12.8816924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.5817123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 5.3416247446
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.3418414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4619014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.8218695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7612490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 9.7611237771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 9.7618462866
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 9.7618986760 16757204 17066447 16280240
MESH:D002294 Carcinoma, Squamous Cell Zinc 9.7616543248
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.3317572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.3317572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.3516120746 18670907 18850075
MESH:D006332 Cardiomegaly valsartan 6.3519597038
MESH:D009202 Cardiomyopathies valsartan 4.1716247790
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 15.0916936243
MESH:D002318 Cardiovascular Diseases Raloxifene 15.0915775269
MESH:D002318 Cardiovascular Diseases valsartan 15.0911230374
MESH:D002318 Cardiovascular Diseases Zinc 15.0916936243
MESH:D002386 Cataract Acetaminophen 6.7410977129
MESH:D002386 Cataract Methylnitrosourea 6.7412484553
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 13.7320889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 13.7312371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 13.7318566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 13.732727394 7505956
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D002779 Cholestasis Cyclosporine 11.6019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.6017333356 15861022 17110522 11677210 16105132 16919318 17681005
MESH:D002779 Cholestasis pirinixic acid 11.6019176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9316354765 15340226 8697196 12621046 15668235
MESH:D003072 Cognition Disorders Raloxifene 4.2215800139
MESH:D003092 Colitis Curcumin 3.7816782535 18200517 16804969
MESH:D003103 Coloboma Curcumin 4.1918809619
MESH:D003110 Colonic Neoplasms Curcumin 3.6419359593 16340194
MESH:D003110 Colonic Neoplasms Fluorouracil 3.6417016597 15001691 18772588 16510598 17169374 17725105 17172411 16340194 17018589 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.4420501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.4418509181 18949393 16331619 17094418 16524972 18288408 15148649 17594712 18448328 17016601 17695437 17255274 16303861 15289873 16282729 14970324 20501625 18383874 16391804 17454858 17401013 18802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7217141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.5018497527
MESH:D003324 Coronary Artery Disease valsartan 3.7417719468
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8012609071
MESH:D003384 Coxsackievirus Infections valsartan 5.4320392896
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.5510525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.5510048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Zinc 3.5519302082
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.6218551238
MESH:D007644 Darier Disease Fluorouracil 4.3816733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7215213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9619031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.8217474826
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.3011298694 16780908 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2318249437
MESH:D003920 Diabetes Mellitus Zinc 3.8616479319
MESH:D003921 Diabetes Mellitus, Experimental valsartan 8.0011508273
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 8.0016684804
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.0318403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0317107852
MESH:D003928 Diabetic Nephropathies Curcumin 24.4718204486
MESH:D003928 Diabetic Nephropathies Estradiol 24.4719279558
MESH:D003928 Diabetic Nephropathies Raloxifene 24.4717451421 15920148 17308373
MESH:D003928 Diabetic Nephropathies Tamoxifen 24.4719279558
MESH:D003928 Diabetic Nephropathies valsartan 24.4711427623 18630688
MESH:D003929 Diabetic Neuropathies Progesterone 4.0917187935
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 5.3321346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 5.3315619225 12958197 19739265 12705907 14550746 11421492 11529661 14725611 12594235 17522070 19923254 16781746 11739529 19416960 12153990 17906064 11287661 18071297 12540782 11461765 11743745 15968718 19164858 16393943 17562736 19085960 16485898 16177239 12392966 16081117 2444490 11834606 19370779 10774834 10915739 14986274 19420014 16109766 10663392 16227642 18713872
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.3320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6819426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4611462148
MESH:D004381 Duodenal Ulcer Curcumin 3.6717351913
MESH:D004417 Dyspnea Oxygen 4.4220016425
MESH:D004487 Edema pirinixic acid 9.3512083418
MESH:D004487 Edema Raloxifene 9.3515860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.3512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4915322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 24.6315138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 24.6312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 24.6317692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 24.6315845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 24.6319031437
MESH:D016889 Endometrial Neoplasms Estradiol 6.4918566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.4917893378 20544844 16202921 19155303
MESH:D004715 Endometriosis Progesterone 7.7616134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.769294722 10568697
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.5620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.5612903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 12.5617638652 15173087 16481741 16785472 16337965
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 12.5615264214 15878914 15547733 16704527 16510608 15150132 15547721 16805852 15623463
MESH:D004938 Esophageal Neoplasms Zinc 12.5616543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7111564622
MESH:D005234 Fatty Liver arsenic trioxide 31.4015073043
MESH:D005234 Fatty Liver Curcumin 31.4019297423
MESH:D005234 Fatty Liver Cyclosporine 31.4019224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.4015345470
MESH:D005234 Fatty Liver pirinixic acid 31.4020131406 19236843
MESH:D005234 Fatty Liver Raloxifene 31.4017473493
MESH:D005234 Fatty Liver Tamoxifen 31.4019224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9816709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0611858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.7819069698
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.8211555667
MESH:D005355 Fibrosis Curcumin 17.9618705752
MESH:D005355 Fibrosis Cyclosporine 17.9612168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.9620067830
MESH:D005355 Fibrosis valsartan 17.9616893502
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8816904648
MESH:D005739 Gas Poisoning Oxygen 4.8020016425
MESH:D005756 Gastritis Acetaminophen 9.7916983495
MESH:D005756 Gastritis Zinc 9.7917241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.3018462866
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.818708960
MESH:D005909 Glioblastoma Curcumin 3.2117596214
MESH:D005910 Glioma Fluorouracil 9.1716145905
MESH:D005910 Glioma Methylnitrosourea 9.179825942
MESH:D005910 Glioma tanshinone 9.1716955220
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 5.1616928621
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1810696789
MESH:D006130 Growth Disorders Zinc 3.7017217573
MESH:D006258 Head and Neck Neoplasms Curcumin 7.0418829502 18462866
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.0415102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.1110048152 11294989
MESH:D006331 Heart Diseases Raloxifene 3.2511110106
MESH:D006333 Heart Failure pirinixic acid 10.5220558911
MESH:D006333 Heart Failure valsartan 10.5219027736
MESH:D006333 Heart Failure Zinc 10.5217162251
MESH:D006335 Heart Injuries Zinc 5.3517074742
MESH:D016481 Helicobacter Infections Zinc 4.1617241300
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9711000095
MESH:D006527 Hepatolenticular Degeneration Zinc 10.0017276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 10.0017063115
MESH:D006529 Hepatomegaly pirinixic acid 6.9518467677 19772884 16221962 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.9515340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6417701891
MESH:D006558 Herpes Genitalis Estradiol 4.6215709030
MESH:D019584 Hot Flashes Estradiol 3.3417088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.638697196 16354765 16959395 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.3816870215
MESH:D006937 Hypercholesterolemia Curcumin 3.6918704882
MESH:D006943 Hyperglycemia pirinixic acid 2.8320558911
MESH:D006973 Hypertension Cyclosporine 11.0410903974
MESH:D006973 Hypertension Raloxifene 11.0417577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 11.0418850075 18670907
MESH:D006973 Hypertension valsartan 11.0418344623 16475468 12692753 18390891 20102058 11427623 10903974 12850387
MESH:D006974 Hypertension, Malignant valsartan 6.0011560862
MESH:D017379 Hypertrophy, Left Ventricular tanshinone 4.8919662366
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4116945680 16569931
MESH:D007022 Hypotension Zinc Sulfate 4.107265320
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.0015869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.0317937319
MESH:D007248 Infertility, Male Methylnitrosourea 6.037193160
MESH:D007249 Inflammation Curcumin 10.1617151092 18403477 16956363
MESH:D007249 Inflammation Progesterone 10.1615869954
MESH:D007249 Inflammation Tamoxifen 10.1619457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.1612878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0418596194 18200517
MESH:D007333 Insulin Resistance bisphenol A 10.7516393666
MESH:D007333 Insulin Resistance Estradiol 10.7516393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.7516306350
MESH:D007414 Intestinal Neoplasms Curcumin 3.8710783313
MESH:D007511 Ischemia Zinc 4.2316584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9716580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0315604871
MESH:D007674 Kidney Diseases Acetaminophen 16.5112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 16.518314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 16.5115618244
MESH:D007674 Kidney Diseases valsartan 16.5110903974 16893502 12164870
MESH:D007674 Kidney Diseases Zinc 16.5116960431
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.0216518626
MESH:D007676 Kidney Failure, Chronic Zinc 9.0216518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 19.8416705839
MESH:D007680 Kidney Neoplasms Cyclosporine 19.8412371664
MESH:D007680 Kidney Neoplasms Estradiol 19.8415610895
MESH:D007680 Kidney Neoplasms Fluorouracil 19.8416985049
MESH:D007680 Kidney Neoplasms Tamoxifen 19.8418625569
MESH:D007889 Leiomyoma Curcumin 9.9118555241
MESH:D007889 Leiomyoma Raloxifene 9.9116973256
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 3.9415237267
MESH:D007938 Leukemia arsenic trioxide 5.8115070760
MESH:D007938 Leukemia Curcumin 5.8118462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.5617077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.5616106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.4019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0716467208 20471514 19850784 17050201 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9517712046 16891316 17107899 11161223 12712474 12018890 19075265 17217047 11468182 12679006 16112521 16966277 19642359 17649720 9834237 17869043 15748426 19225113 16331271 16823087 19035177 15213294 16330433 15336539 15622746
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.4316882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.4316106398
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 3.9115526292
MESH:D008064 Lipidoses Tamoxifen 2.8715342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 7.9517355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 7.9514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 7.9515474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 7.9518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 7.9512878042
MESH:D008106 Liver Cirrhosis, Experimental valsartan 7.9515504291 15619341 16872305
MESH:D008107 Liver Diseases Acetaminophen 3.7012969438 12587719 19460945 16610002 19784758 16611625 19014921 11587558
MESH:D008107 Liver Diseases Curcumin 3.7016956363
MESH:D017114 Liver Failure, Acute Acetaminophen 2.8816871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 15.7918177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 15.7914682389
MESH:D008113 Liver Neoplasms Fluorouracil 15.7915113037 18383874 17045692 16603448
MESH:D008113 Liver Neoplasms pirinixic acid 15.7916377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 15.7916684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 15.7916984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 8.338603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 8.3320377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 8.3312151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0415213294
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.0716080182
MESH:D008171 Lung Diseases Ozone 3.108266340 19066396
MESH:D055370 Lung Injury Asbestos, Crocidolite 13.0217365036
MESH:D055370 Lung Injury Oxygen 13.0218339021
MESH:D055370 Lung Injury Ozone 13.0220417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 14.2114755239
MESH:D008175 Lung Neoplasms arsenic trioxide 14.2119825857 11798837
MESH:D008175 Lung Neoplasms bexarotene 14.2117849452
MESH:D008175 Lung Neoplasms Curcumin 14.2119359593 16243823 18462866
MESH:D008175 Lung Neoplasms Fluorouracil 14.2115246190
MESH:D008175 Lung Neoplasms Methylnitrosourea 14.2118062963
MESH:D008175 Lung Neoplasms Ozone 14.218597069 7614698
MESH:D008175 Lung Neoplasms Tamoxifen 14.2118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 14.2111884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3815086387
MESH:D008223 Lymphoma Curcumin 7.0218462866
MESH:D008223 Lymphoma Methylnitrosourea 7.0216257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.4014633661
MESH:D016399 Lymphoma, T-Cell Curcumin 4.3016173963
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.7511161223
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3619428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 20.1419196723 15591091 19196722
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 20.1416891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 20.1414633655 10767621 17020996 15688392 19196723 16619500 16827153 15313902 10838139 15113128 17131329 11751437 16051031 11807958 12931682 14999141 16944150
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 20.1417203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 20.1414580682 11731420 19196722 16827153 19196723
MESH:D008325 Mammary Neoplasms, Experimental Zinc 20.1412773700
MESH:D020149 Manganese Poisoning Estradiol 11.2719453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.2719453300
MESH:D008545 Melanoma Curcumin 3.2017885582 18462866
MESH:D008545 Melanoma Tamoxifen 3.2012393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.7815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1719513568
MESH:D008569 Memory Disorders Curcumin 3.7717263510
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0116166281 16966607 18303189
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3716801185
MESH:D008679 Metaplasia Ozone 4.6910496685
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.1415863610
MESH:D009062 Mouth Neoplasms Fluorouracil 3.3216757204 18986760
MESH:D009101 Multiple Myeloma arsenic trioxide 10.5114977855 19417148 15949261 19549372 11468182
MESH:D009101 Multiple Myeloma Curcumin 10.5119372569
MESH:D009101 Multiple Myeloma Raloxifene 10.5116497877
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.5117962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1116239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.9016105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 1.9719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.2216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.2216411023
MESH:D009232 Myxoma Raloxifene 5.1416343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.4518551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 9.0416624393
MESH:D009361 Neoplasm Invasiveness Curcumin 9.0418495463
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.3819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3719410462
MESH:D009369 Neoplasms Fluorouracil 7.1518239605 16928823 18600527
MESH:D009369 Neoplasms Methylnitrosourea 7.1515533788
MESH:D009369 Neoplasms pirinixic acid 7.1517405874
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 4.0812696579
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 15.9219196722
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 15.9212497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 15.9219200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3317289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9419348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 14.1211399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 14.1216427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.1214600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.2218462866
MESH:D009436 Neural Tube Defects arsenic trioxide 2.8510525206
MESH:D009442 Neurilemmoma Methylnitrosourea 5.0811555667
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.5418514411
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1616436463
MESH:D009765 Obesity Curcumin 4.2219297423
MESH:D009765 Obesity pirinixic acid 4.2220558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.0812819281 16049721
MESH:D010024 Osteoporosis Curcumin 6.5618719352
MESH:D010024 Osteoporosis Raloxifene 6.5617882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.8517893378 15579764 17823083 15758505
MESH:D010049 Ovarian Diseases bisphenol A 4.5811985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.1416624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Curcumin 10.1419020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 10.1419401270
MESH:D010051 Ovarian Neoplasms Progesterone 10.1417393432 16525653
MESH:D010146 Pain Acetaminophen 2.0816870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.0915580305
MESH:D010190 Pancreatic Neoplasms Curcumin 11.0919196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms Fluorouracil 11.0916500647 16929163 19003803 15113037
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 11.0916965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3111578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.6912065085
MESH:D010235 Paraganglioma arsenic trioxide 3.7919927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8312520081
MESH:D010538 Peritonitis Ozone 3.7416369182
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5010923243
MESH:D011014 Pneumonia Ozone 3.9918007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1718163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.8812371664
MESH:D011225 Pre-Eclampsia Zinc 3.8617114810
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.1610548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.1611222880 11896295 11118676 11399792
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3715572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.3420887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.3420887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.3419131511
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3416740699
MESH:D011471 Prostatic Neoplasms Calcitriol 3.3416644109 18247401 12479363 15754350 16289102
MESH:D011471 Prostatic Neoplasms Curcumin 3.3418226269 11398177 15129424 10851300 18769126 18156803 12497104
MESH:D011471 Prostatic Neoplasms Estradiol 3.3416740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3418626508 19082440
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 3.3412376480 15682402
MESH:D011471 Prostatic Neoplasms Raloxifene 3.3416536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.3415067354
MESH:D011471 Prostatic Neoplasms Zinc 3.3416517595 16700911 12429649 16606632
MESH:D011507 Proteinuria valsartan 4.4817664856 12164870 18344623
MESH:D011537 Pruritus Ethinyl Estradiol 2.9115861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.0816882103
MESH:D011629 Puberty, Precocious bisphenol A 4.3810548101
MESH:D011656 Pulmonary Emphysema Curcumin 4.1719168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 5.6817365031 15814490 17975199 17322281
MESH:D011658 Pulmonary Fibrosis valsartan 5.6817241526
MESH:D011693 Purpura Raloxifene 5.1415770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6718286688 15538739 18722050 16160472
MESH:D015427 Reperfusion Injury pirinixic acid 2.1819058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 8.2518379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 8.2517627322 18339021
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4518990726
MESH:D012162 Retinal Degeneration Methylnitrosourea 8.3818172121 18155124
MESH:D012162 Retinal Degeneration Zinc 8.3816584753
MESH:D012175 Retinoblastoma Methylnitrosourea 5.0811555667
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7018045962
MESH:D012509 Sarcoma Curcumin 3.7718462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.5716646077
MESH:D012640 Seizures 2,4-dinitrotoluene 2.2718551238
MESH:D018805 Sepsis Curcumin 3.7418389075
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 8.3212065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 8.328532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.3216192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.1816709447
MESH:D013088 Spermatocele Tamoxifen 10.1816709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.5216503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.5219457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.4017007042
MESH:D013274 Stomach Neoplasms Fluorouracil 4.4015786421 19015929 18567086 16424979 16951190 17522103 17498489 18396642 17172411 19084572
MESH:D013274 Stomach Neoplasms Methylnitrosourea 4.4016257854 15930296 18593901
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 4.4012958204 17575124
MESH:D013276 Stomach Ulcer Curcumin 3.1516631530 19188055
MESH:D020521 Stroke Raloxifene 3.5016837676
MESH:D019966 Substance-Related Disorders bisphenol A 3.5816045194 16684133
MESH:D013398 Sudden Infant Death Oxygen 5.1412563064
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8115669648
MESH:D013953 Thymus Neoplasms Methylnitrosourea 4.8211418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4912697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.5219014326
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 6.527505956 3078959
MESH:D013978 Tibial Fractures Estradiol 12.3319048282
MESH:D013978 Tibial Fractures Raloxifene 12.3319048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.8816280240
MESH:D014062 Tongue Neoplasms Zinc 8.8816543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5615213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 13.9816049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 13.9811780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Curcumin 13.9818593936
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 13.9817572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 13.988653321 16712894 17572228
MESH:D014565 Urogenital Neoplasms Curcumin 4.8618462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.9110091137
MESH:D014581 Urticaria Acetaminophen 2.6110982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.5316803524
MESH:D014591 Uterine Diseases bisphenol A 4.5914652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9214692618
MESH:D014605 Uveitis Cyclosporine 3.571336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1812125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.7916837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1814671159 15869587
MESH:D020257 Ventricular Remodeling valsartan 5.2919027736
MESH:D014846 Vulvar Neoplasms Raloxifene 5.1416343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8315886252
MESH:D014985 Xerophthalmia Cyclosporine 4.0317120751
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
Pharmacogenomics Knowledge Base Top
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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