AutismKB 2.0

Annotation Detail for DUSP8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DUSP8 ( C11orf81,FLJ42476,FLJ42958,HB5,HVH-5,HVH8 )
Gene Full Name: dual specificity phosphatase 8
Band: 11p15.5
Quick LinksEntrez ID:1850; OMIM: 602038; Uniprot ID:CK081_HUMAN; ENSEMBL ID: ENSG00000184545; HGNC ID: 3074
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
No data
Pathway IDPathway Name
200116ATF-2 transcription factor network
200054Regulation of p38-alpha and p38-beta
Pathway IDPathway Name
P00046Oxidative stress response
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in increased expression of DUSP8 mRNAincreases expression 18544908
D000082 Acetaminophen Acetaminophen affects the expression of DUSP8 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of DUSP8 mRNAincreases expression 18544908
C006632 arsenic trioxide arsenic trioxide results in increased expression of DUSP8 mRNAincreases expression 20458559
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of DUSP8 mRNAaffects expression 17331233
D004317 Doxorubicin Doxorubicin results in decreased expression of DUSP8 mRNAdecreases expression 17888722
D004958 Estradiol Estradiol affects the expression of DUSP8 mRNAaffects expression 15598610
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DUSP8 mRNAaffects cotreatment|increases expression 17942748
D006851 Hydrochloric Acid Hydrochloric Acid results in decreased expression of DUSP8 mRNAdecreases expression 15046208
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of DUSP8 mRNAaffects binding|decreases expression|increases activity 19710929
D012643 Selenium Selenium results in increased expression of DUSP8 mRNAincreases expression 19244175
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DUSP8 mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0411752688 15322242 14514962
MESH:D000138 Acidosis Hydrochloric Acid 5.3911574821 20872349 19262391 15920416 12771618 16144966
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.9517183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 6.0320597076
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1617505938
MESH:D055371 Acute Lung Injury Hydrochloric Acid 9.8219060228 16759491 11953099 19760209 11850527 19094174 15970105
MESH:D055371 Acute Lung Injury pirinixic acid 9.8218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.4511798837 19825857
MESH:D000230 Adenocarcinoma Doxorubicin 10.4517418594
MESH:D000230 Adenocarcinoma Estradiol 10.4511473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.4514692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.5616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.5616835633
MESH:D000419 Albuminuria Doxorubicin 4.7021441931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0811748828
MESH:D000799 Angioedema Acetaminophen 4.0610982225
MESH:D000860 Anoxia Hydrochloric Acid 5.5015090967
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.6411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.7415885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 23.2216206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 23.2215920416
MESH:D001778 Blood Coagulation Disorders pirinixic acid 23.2219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 23.2212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.0115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8515746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.9214601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.9417150277
MESH:D001943 Breast Neoplasms Doxorubicin 1.8716096432 18382427 15939500 17369602 15136595 17983394 19526202 15994142 16322301 16115903 16935488 15668708 16264153 18234424 15567936 18628466 18695136 15993339 17426702 16826403 15634643 16595493 11325840 15692762
MESH:D001943 Breast Neoplasms Estradiol 1.8712948864 17261762 14630087 17018787 19861407 18497071 16675129 17289903
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8720435547
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 4.7012378975
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.6815578804
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.4811589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.6616111702
MESH:D002276 Carcinoid Tumor Doxorubicin 5.0316051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9116835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.743084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.7411135700 14691202 15553829 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 6.7418059187 16234567 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.7416924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.0919014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.221485588 16201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.2512490120
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 2.676189445
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4416120746 18670907 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.6217007740 15476868 16242529 17329180 16952015 16731534 17974986 17131338 17382496 18627295 15811867 17519947 17924179 17928571 16455267 16651473 15792986 16269455 16278810 17351982 16612575 17308081 16109756 15505089 16364871
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9817334414 16243910
MESH:D002386 Cataract Acetaminophen 2.6610977129
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.8618566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 8.0915861022 17333356 17110522 16105132 17681005 16919318 11677210
MESH:D002779 Cholestasis pirinixic acid 8.0919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1516354765 15340226 15668235 8697196 12621046
MESH:D003092 Colitis Selenium 3.9517936198
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6320501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.6318802399 18259882
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1817141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.3512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.5110525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5110048152 15322242 20055451
MESH:D003556 Cystitis Hydrochloric Acid 5.6820719367 12599022 12853844 19279288
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 6.0317714534
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.2415213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4818249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6917107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.5419279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.2916485898 16227642 16177239 14725611 19164858 19416960 12594235 10915739 19085960 11287661 17562736 16781746 15968718 16109766 16393943 17522070 19370779 16081117 10774834 19739265 12153990 12705907 15619225 11421492 14550746 14986274 2444490 12958197 19923254 11529661 19420014 18071297 18713872 11834606 12392966 17906064 11739529 11461765 11743745 10663392 12540782
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 9.2917416283
MESH:D056486 Drug-Induced Liver Injury Selenium 9.2915131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.2920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.3219426721
MESH:D004362 Drug Toxicity Doxorubicin 8.4618602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.4611462148
MESH:D004487 Edema pirinixic acid 7.0012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.0011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.1216714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.3512538720
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.8317359293
MESH:D016889 Endometrial Neoplasms Estradiol 7.8318566989 11473722 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.159294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.3718037988
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.9919566590
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3412903497
MESH:D004941 Esophagitis Hydrochloric Acid 6.1912928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 6.2320516732 14621274 11346197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1211564622
MESH:D005234 Fatty Liver arsenic trioxide 13.8915073043
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.8915345470
MESH:D005234 Fatty Liver pirinixic acid 13.8920131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.6311858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.7819069698
MESH:D005355 Fibrosis Hydrochloric Acid 9.6518497604
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.6520067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.4216904648
MESH:D005739 Gas Poisoning Hydrochloric Acid 5.6812378975
MESH:D005756 Gastritis Acetaminophen 3.8916983495
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 5.4919951613 19957777 12212954 20616304 20516732 20545468
MESH:D005909 Glioblastoma Doxorubicin 3.4317150277
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.8110696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.6215692506
MESH:D006356 Heartburn Hydrochloric Acid 5.9919566590
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4011294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 3.5817888722 17875725 12587719 16879835 16330681 14766674 16244371 16495754 16144979 18006777 16707910 16244372 18674790
MESH:D006333 Heart Failure Doxorubicin 12.2917481944
MESH:D006333 Heart Failure pirinixic acid 12.2920558911
MESH:D006333 Heart Failure Selenium 12.2917162251
MESH:D006394 Hemangiosarcoma Doxorubicin 4.0415692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4811000095
MESH:D006529 Hepatomegaly pirinixic acid 8.8519772884 19176532 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.8516120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 5.2515709030
MESH:D006689 Hodgkin Disease Doxorubicin 3.5318501091 15147373 17606976
MESH:D019584 Hot Flashes Estradiol 3.9717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.2616354765 15340226 8697196 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.8116870215
MESH:D006940 Hyperemia Hydrochloric Acid 5.8412646421
MESH:D006943 Hyperglycemia pirinixic acid 3.3120558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9518670907 18850075
MESH:D006975 Hypertension, Portal Hydrochloric Acid 5.5216984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.5519262391
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9816569931 16945680
MESH:D007022 Hypotension Hydrochloric Acid 4.9111574821
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5717937319
MESH:D007249 Inflammation Hydrochloric Acid 5.5811574821
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.5812200463 12878042
MESH:D007251 Influenza, Human Selenium 4.4116624496
MESH:D007333 Insulin Resistance Estradiol 7.4916393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 7.4916306350
MESH:D007410 Intestinal Diseases Hydrochloric Acid 5.1411574821
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.4816580747
MESH:D007674 Kidney Diseases Acetaminophen 10.5212587719 15629191
MESH:D007674 Kidney Diseases Doxorubicin 10.5215699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 10.5215618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 10.4616707910
MESH:D007676 Kidney Failure, Chronic Selenium 10.4616518626
MESH:D007680 Kidney Neoplasms Estradiol 3.0915610895
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 6.5816498863
MESH:D007826 Laryngismus Hydrochloric Acid 6.5811510729
MESH:D007938 Leukemia arsenic trioxide 2.8915070760
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.3716085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.9317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.5016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.5314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.9019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1620471514 19850784 16467208 16968895 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.309834237 12679006 11468182 19225113 19075265 16966277 16112521 12018890 17107899 17869043 11161223 15622746 19035177 16330433 17649720 12712474 15213294 17217047 19642359 15748426 16823087 15336539 16891316 16331271 17712046
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.5116882451
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 4.1416984587
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 5.0616595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.0614659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 5.0615474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.0612878042
MESH:D008107 Liver Diseases Acetaminophen 1.6619784758 16611625 12969438 11587558 19014921 12587719 19460945 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3717185352 16871587
MESH:D008113 Liver Neoplasms arsenic trioxide 7.6314682389
MESH:D008113 Liver Neoplasms pirinixic acid 7.6316377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.6316984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 10.3620377131
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 10.3616842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.3612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.4615213294
MESH:D008171 Lung Diseases Hydrochloric Acid 4.3716784557
MESH:D055370 Lung Injury Asbestos, Crocidolite 10.1717365036
MESH:D055370 Lung Injury Hydrochloric Acid 10.1721114838 16129981 18497604 15044056 11395602 18339021 15607125 19644408 18573544 15090967 21311175 17627322 19262391 20597076
MESH:D008175 Lung Neoplasms arsenic trioxide 3.5111798837 19825857
MESH:D008175 Lung Neoplasms Doxorubicin 3.516189445 17418594
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.5111884234 19555203
MESH:D008223 Lymphoma Doxorubicin 3.5616098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.9117654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.7415621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 10.5315458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.5311807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 10.5315318939
MESH:D020149 Manganese Poisoning Estradiol 4.7019453300
MESH:D008545 Melanoma Doxorubicin 2.3016827129
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7419513568
MESH:D008654 Mesothelioma Asbestos, Crocidolite 10.5516966607 18303189 16166281
MESH:D008654 Mesothelioma Doxorubicin 10.5517638057
MESH:D008654 Mesothelioma Selenium 10.5515107826
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.6415792986
MESH:D052016 Mucositis Doxorubicin 4.9817415656
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2011468182 14977855 19549372 19417148 15949261
MESH:D009135 Muscular Diseases pirinixic acid 3.6816239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.8918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2216105982 16882451
MESH:D009203 Myocardial Infarction Doxorubicin 9.9215857846 19429709
MESH:D009203 Myocardial Infarction Hydrochloric Acid 9.9218534312
MESH:D009203 Myocardial Infarction pirinixic acid 9.9219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.6116810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.6116411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.1216624393
MESH:D009362 Neoplasm Metastasis Doxorubicin 3.0018259882
MESH:D009369 Neoplasms pirinixic acid 2.0117405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.9317289903
MESH:D009401 Nephrosis Doxorubicin 4.9416636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 4.1216889571 15640375
MESH:D009421 Nervous System Malformations Estradiol 10.0111399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.0114600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.2010525206
MESH:D009447 Neuroblastoma Doxorubicin 3.3315555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9918514411
MESH:D009765 Obesity pirinixic acid 1.8420558911
MESH:D009784 Occupational Diseases Hydrochloric Acid 4.8912378975
MESH:D012516 Osteosarcoma Doxorubicin 4.2315930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.9616624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 4.9619401270
MESH:D010146 Pain Acetaminophen 2.5016870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5715580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8411578682
MESH:D010235 Paraganglioma arsenic trioxide 4.3119927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4712520081
MESH:D003557 Phyllodes Tumor Doxorubicin 5.3717983394
MESH:D010954 Plasmacytoma Selenium 5.1115087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.0710923243
MESH:D010997 Pleural Neoplasms Doxorubicin 5.3717638057
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 5.5618497604 15607125 18573544 15970105
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.7218163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.3811896295 11118676 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.0220887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5719131511
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.5716729912 16868541 15897917 15749863 16888761 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 2.5716740699
MESH:D011537 Pruritus Ethinyl Estradiol 3.5115861022 16919318
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 6.2320597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 5.4315090967
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.0717365031 17322281 15814490 17975199
MESH:D051437 Renal Insufficiency Doxorubicin 4.4017922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.4519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 4.9118339021 18549715 16784557 16129981 17627322
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 6.5811510729
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0018990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 5.3820516732
MESH:D012509 Sarcoma Doxorubicin 4.1216767912 17203757 15625365 18313854 17710206 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 10.8216646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.8214601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.9817846226
MESH:D012878 Skin Neoplasms Doxorubicin 5.8915692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.8916192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.7415625365 17203757 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 4.1616709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013276 Stomach Ulcer Hydrochloric Acid 4.3615309881 17189318 16755016
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.1212697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.6919014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.6916010429 17909728
MESH:D013978 Tibial Fractures Estradiol 4.9019048282
MESH:D016171 Torsades de Pointes arsenic trioxide 4.1515213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.4212973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 5.4217653716
MESH:D014581 Urticaria Acetaminophen 3.1210982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.4614692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.8112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6815869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.4016364871 17334414 17638931 17678736
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4715886252
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved