AutismKB 2.0

Annotation Detail for EDA


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EDA ( ED1,ED1-A1,ED1-A2,EDA1,EDA2,HED,STHAGX1,XHED,XLHED )
Gene Full Name: ectodysplasin A
Band: Xq13.1
Quick LinksEntrez ID:1896; OMIM: 300451; Uniprot ID:EDA_HUMAN; ENSEMBL ID: ENSG00000158813,ENSG00000251315; HGNC ID: 3157
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04060Cytokine-cytokine receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
primary tooth development
DEVELOPMENTAL
Desease Name
Primary tooth development (number of teeth)
Primary tooth development (time to first tooth eruption)
Desease Name
Ectodermal dysplasia, anhidrotic, X-linked
Tooth agenesis, selective, X-linked 1
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D014810 Vitamin E Vitamin E results in decreased expression of EDA mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.8416050911
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9319769572
OMIM:304110 CRANIOFRONTONASAL SYNDROME marker/mechanism 17941886
MESH:C538011 Eales disease Vitamin E 6.129068938
MESH:D053358 Ectodermal Dysplasia 1, Anhidrotic marker/mechanism
MESH:D006330 Heart Defects, Congenital Vitamin E 3.2216080930
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8416490937 16863852
MESH:D019584 Hot Flashes Vitamin E 5.3914716179
MESH:D007251 Influenza, Human Vitamin E 5.6316624496
MESH:D007674 Kidney Diseases Vitamin E 3.0712488133
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9116169303
MESH:D008171 Lung Diseases Vitamin E 3.5216863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2315084515
MESH:D012871 Skin Diseases Vitamin E 2.5418709164
MESH:D020521 Stroke Vitamin E 3.9716517955
OMIM:313500 TOOTH AGENESIS, SELECTIVE, X-LINKED, 1 marker/mechanism
Pathway ID Pathway Name
KEGG:04060 Cytokine-cytokine receptor interaction
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved