Annotation Detail for PGAM5
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of PGAM5 mRNA | affects expression | 21346803
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PGAM5 mRNA | decreases expression | 20382639
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of PGAM5 mRNA | affects expression | 17555576
|
| C031280 |
pyrazole |
pyrazole results in increased expression of PGAM5 mRNA | increases expression | 17945193
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.66 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.88 | 14692618 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
4.02 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.89 | 15885639 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
1.79 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.98 | 20889678 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.17 | 15861022 16919318 11677210 16105132 17110522 17681005 17333356 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.58 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.55 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
pyrazole |
4.55 | 12499123 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.69 | 12538720 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.15 | 20426865 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
3.24 | 15345470 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.37 | 16569931 16945680 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.92 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.73 | 17937319 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.32 | 16705839 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.49 | 18551238 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
3.82 | 12819281 16049721 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.15 | 11578682 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
3.94 | 16919318 15861022 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
2.79 | 18551238 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
4.66 | 16709447 |
| MESH:D013733 |
Testicular Diseases |
|
pyrazole |
5.45 | 6499806 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.08 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.52 | 15669648 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.41 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.95 | 10091137 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.80 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
3.97 | 14671159 15869587 |
Related Pathway Information