AutismKB 2.0

Annotation Detail for EIF2C3


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Basic Information Top
Gene Symbol:EIF2C3 ( AGO3,FLJ12765,MGC86946 )
Gene Full Name: eukaryotic translation initiation factor 2C, 3
Band: 1p34.3
Quick LinksEntrez ID:192669; OMIM: 607355; Uniprot ID:AGO3_HUMAN; ENSEMBL ID: ENSG00000126070; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Regulatory RNA pathways
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of EIF2C3 mRNAdecreases expression 20018196
C004648 testosterone enanthate testosterone enanthate affects the expression of EIF2C3 mRNAaffects expression 17440010
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.8217440010
Pathway ID Pathway Name
REACT:12472 Regulatory RNA pathways
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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