AutismKB 2.0

Annotation Detail for EGR3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EGR3 ( MGC138484,PILOT )
Gene Full Name: early growth response 3
Band: 8p21.3
Quick LinksEntrez ID:1960; OMIM: 602419; Uniprot ID:EGR3_HUMAN; ENSEMBL ID: ENSG00000179388; HGNC ID: 3240
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200039Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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Related Diseases/Disorders Top
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Desease IDDesease Name
2069Schizophrenia
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of EGR3 mRNAdecreases expression 19933214
C026114 2-xylene 2-xylene results in increased expression of EGR3 mRNAincreases expression 20359517
D000643 Ammonium Chloride Ammonium Chloride affects the expression of EGR3 mRNAaffects expression 16483693
D001554 Benzene Benzene results in increased expression of EGR3 mRNAincreases expression 20359517
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of EGR3 mRNAaffects expression 20382639
C095105 bexarotene bexarotene results in decreased expression of EGR3 mRNAdecreases expression 17178900
C006780 bisphenol A bisphenol A results in increased expression of EGR3 mRNAincreases expression 15223131
15159206
D003024 Clozapine EGR3 protein affects the susceptibility to Clozapineaffects response to substance 17637609
D003042 Cocaine Cocaine results in increased expression of EGR3 mRNAincreases expression 16459018
D016572 Cyclosporine Cyclosporine inhibits the reaction [Zymosan results in increased expression of EGR3 mRNA]decreases reaction|increases expression 17312158
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of EGR3 mRNAincreases expression 15159206
D002117 Calcitriol Calcitriol results in increased expression of EGR3 mRNAincreases expression 16002434
D004610 Ellagic Acid Ellagic Acid results in decreased expression of EGR3 mRNAdecreases expression 12002526
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGR3 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of EGR3 mRNAincreases expression 15913882
19619570
15159206
15223131
D004964 Estriol Estriol results in increased expression of EGR3 mRNAincreases expression 15159206
D004970 Estrone Estrone results in increased expression of EGR3 mRNAincreases expression 15159206
C004912 ethylbenzene ethylbenzene results in increased expression of EGR3 mRNAincreases expression 20359517
D019833 Genistein Genistein results in increased expression of EGR3 mRNAincreases expression 15159206
D008731 Methoxychlor Methoxychlor results in increased expression of EGR3 mRNAincreases expression 15159206
C005219 methyl cellosolve methyl cellosolve results in increased expression of EGR3 mRNAincreases expression 19643169
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of EGR3 mRNAincreases expression 20713471
D008752 Methylene Chloride Methylene Chloride results in increased expression of EGR3 mRNAincreases expression 20359517
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased expression of EGR3 mRNAincreases expression 16809437
C025256 nonylphenol nonylphenol results in increased expression of EGR3 mRNAincreases expression 15159206
C006253 pirinixic acid NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of EGR3 mRNA]decreases expression|increases reaction 17950772
C006253 pirinixic acid pirinixic acid results in decreased expression of EGR3 mRNAdecreases expression 17950772
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGR3 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of EGR3 mRNAdecreases expression 17517823
19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of EGR3 mRNAdecreases expression 19933214
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EGR3 mRNAincreases expression 16962184
D014050 Toluene Toluene results in increased expression of EGR3 mRNAincreases expression 20359517
D014241 Trichloroethylene Trichloroethylene results in increased expression of EGR3 mRNAincreases expression 20359517
C066075 vanadium pentoxide vanadium pentoxide affects the expression of EGR3 mRNAaffects expression 17459161
C121611 VIVIT peptide VIVIT peptide inhibits the reaction [Zymosan results in increased expression of EGR3 mRNA]decreases reaction|increases expression 17312158
D015054 Zymosan CLEC7A protein affects the reaction [Zymosan results in increased expression of EGR3 mRNA]affects reaction|increases expression 17312158
D015054 Zymosan Cyclosporine inhibits the reaction [Zymosan results in increased expression of EGR3 mRNA]decreases reaction|increases expression 17312158
D015054 Zymosan VIVIT peptide inhibits the reaction [Zymosan results in increased expression of EGR3 mRNA]decreases reaction|increases expression 17312158
D015054 Zymosan Zymosan results in increased expression of EGR3 mRNAincreases expression 17312158
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 7.746499812 3652986 6474471
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.7415322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.2618287403
MESH:D055371 Acute Lung Injury pirinixic acid 2.8518653653
MESH:D000230 Adenocarcinoma Estradiol 4.2011473722
MESH:D000230 Adenocarcinoma Genistein 4.2011473722
MESH:D000236 Adenoma Methylcholanthrene 3.3310545420 6695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.9216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.9216835633
MESH:D000380 Agranulocytosis Clozapine 4.7714617031 16160616 12649775
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2015469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.1511748828
MESH:D000740 Anemia Zymosan 8.1518664788
MESH:D000741 Anemia, Aplastic Benzene 4.1511369114 14761424 17661222
MESH:D000748 Anemia, Macrocytic methyl cellosolve 6.053699323
MESH:D001169 Arthritis, Experimental Zymosan 3.9415142272 15944321 16872482 15188379 17659584
MESH:D053627 Asthenozoospermia methyl cellosolve 5.233987992
MESH:D050197 Atherosclerosis Methylcholanthrene 3.2811922910
MESH:D001284 Atrophy methyl cellosolve 4.916705890 3699323 2626667
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.8919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.8912125929
MESH:D001836 Body Weight Changes 2-xylene 11.107457028
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 11.1015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5815746008
MESH:D001855 Bone Marrow Diseases Benzene 4.9316183116
MESH:D001862 Bone Resorption bisphenol A 3.6011985600
MESH:D001943 Breast Neoplasms Benzene 7.9311921183 17162533
MESH:D001943 Breast Neoplasms bexarotene 7.9316818667 16344269
MESH:D001943 Breast Neoplasms bisphenol A 7.9317123778
MESH:D001943 Breast Neoplasms Calcitriol 7.9311237771
MESH:D001943 Breast Neoplasms Diethylstilbestrol 7.9315324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 7.9319861407 17289903 17018787 12948864 16675129 14630087 18497071 17261762
MESH:D001943 Breast Neoplasms Genistein 7.9316541309 16873071 17200150
MESH:D001943 Breast Neoplasms Methylcholanthrene 7.9317474063
MESH:D001943 Breast Neoplasms Methylene Chloride 7.9315986119
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 7.9320435547
MESH:D001943 Breast Neoplasms Trichloroethylene 7.9315986119
MESH:D001991 Bronchitis vanadium pentoxide 5.9417459161
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1716111702
MESH:D002277 Carcinoma Methylcholanthrene 7.5710545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.5716835633
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 4.3915948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 4.3916924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 4.3916924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.6917123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1216247446
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 2.5411237771
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2116120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Genistein 3.1016332659
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 14.3820889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 14.3812371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.3818566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 14.3816192471
MESH:D002547 Cerebral Palsy Toluene 5.559294310
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9216835633
MESH:D002764 Cholecystitis methyl cellosolve 5.506499794
MESH:D002779 Cholestasis Cyclosporine 7.0419486331
MESH:D002779 Cholestasis pirinixic acid 7.0419176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9815668235 15340226 12621046 8697196 16354765
MESH:D019970 Cocaine-Related Disorders Cocaine 5.4219606084
MESH:D003072 Cognition Disorders Clozapine 4.6817123785
MESH:D003110 Colonic Neoplasms Genistein 2.2417182828
MESH:D000013 Congenital Abnormalities methyl cellosolve 8.6112530607 6499821
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.6117141729 14669216
MESH:D019465 Craniofacial Abnormalities Benzene 3.7815643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7810048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Toluene 3.789294310
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2816002989 12952375
MESH:D003643 Death Toluene 5.376431079
MESH:D003872 Dermatitis Benzene 4.4815902427
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2918249437
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 6.7516402076
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.7516647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.7517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.1719279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.2515331141
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.8720420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 3.877120509
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5511462148
MESH:D050171 Dyslipidemias Clozapine 3.9716402076
MESH:D004487 Edema pirinixic acid 10.0012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.0011000095 12711302
MESH:D004487 Edema Zymosan 10.007907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6015322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 3.6615138306
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 18.6316402032
MESH:D004714 Endometrial Hyperplasia Estriol 18.6316402032
MESH:D004714 Endometrial Hyperplasia Genistein 18.6316402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 11.4116804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 11.4119148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Genistein 11.4111473722
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7710568697 9294722
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.0020426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8011564622
MESH:D005234 Fatty Liver Cyclosporine 6.6919224547
MESH:D005234 Fatty Liver pirinixic acid 6.6919236843 20131406
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.4816513791 16611131 16002989 15751030 16534752
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1711858732
MESH:D005327 Fetal Resorption methyl cellosolve 5.246499821 6474471 3987992 6499812
MESH:D020567 Fetal Weight methyl cellosolve 5.506474471 6499812 6499821
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.6414633661 10962813
MESH:D005355 Fibrosis Cyclosporine 7.5212639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.5220067830
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 5.203652986
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.6516452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.928708960
MESH:D005909 Glioblastoma Genistein 3.0716598420
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2910696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.1811294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.3620558911
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.486499821
MESH:D006402 Hematologic Diseases Benzene 4.3816183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1315720958
MESH:D006461 Hemolysis methyl cellosolve 5.1517874071
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0711000095
MESH:D006505 Hepatitis Zymosan 4.4219110552
MESH:D006529 Hepatomegaly 2-xylene 12.927457028 7457013
MESH:D006529 Hepatomegaly pirinixic acid 12.9216221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.9215340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.7315709030
MESH:D019584 Hot Flashes Estradiol 3.4517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.758697196 16959395 15340226 18606429 16354765
MESH:D006943 Hyperglycemia pirinixic acid 2.9320558911
MESH:D006948 Hyperkinesis Clozapine 4.6116046005
MESH:D006965 Hyperplasia Diethylstilbestrol 4.1512960047 14722030
MESH:D006973 Hypertension Benzene 7.9317940673
MESH:D006973 Hypertension Cyclosporine 7.9310903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.9318670907 18850075
MESH:D007021 Hypospadias Diethylstilbestrol 4.2916002989
MESH:D007246 Infertility Diethylstilbestrol 4.0715036965
MESH:D007248 Infertility, Male Methoxychlor 7.0411955947 16467254
MESH:D007248 Infertility, Male methyl cellosolve 7.043987992
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.7912878042 12200463
MESH:D007249 Inflammation Zymosan 4.7911289658 8014878
MESH:D007333 Insulin Resistance bisphenol A 11.2116393666
MESH:D007333 Insulin Resistance Estradiol 11.2116393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 11.2116306350
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.5417553498
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0716580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1415604871
MESH:D007674 Kidney Diseases Cyclosporine 5.378314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 5.3715618244
MESH:D007680 Kidney Neoplasms Cyclosporine 15.9012371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 15.9015003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 15.9015610895
MESH:D007680 Kidney Neoplasms Estrone 15.9015610895
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7717184923
MESH:D007938 Leukemia Benzene 6.1515935818 14694614 17119257 18335105
MESH:D007938 Leukemia Genistein 6.1517468513 18980019
MESH:D007951 Leukemia, Myeloid Benzene 4.0617506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.6519478238
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 4.296499821
MESH:D008064 Lipidoses Clozapine 3.7517567588
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.6114659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.6117823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.6115474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.6112878042
MESH:D008113 Liver Neoplasms Diethylstilbestrol 6.7215890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 6.7216377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 6.7216984957
MESH:D008114 Liver Neoplasms, Experimental Benzene 12.7212562636
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 12.721399818 598648
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.7212151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 12.727955063
MESH:D017563 Lung Diseases, Interstitial Benzene 4.5114698565
MESH:D008175 Lung Neoplasms Benzene 8.0612562636
MESH:D008175 Lung Neoplasms bexarotene 8.0617849452
MESH:D008175 Lung Neoplasms Methylcholanthrene 8.0616271038 7750092 11893704 20512841 17909032 16337739 6695378 10545420 21163286 9230183 1399818 15390079 20970405
MESH:D008175 Lung Neoplasms Methylene Chloride 8.0615172992
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.0619555203 11884234
MESH:D008175 Lung Neoplasms vanadium pentoxide 8.0612376484
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8515166399
MESH:D008223 Lymphoma Benzene 7.1517584886 17119257
MESH:D008223 Lymphoma Diethylstilbestrol 7.1515700306
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.8611161223
MESH:D008231 Lymphopenia methyl cellosolve 5.483699323
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2216002989
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.1512562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 12.7911921183
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 12.7919196722 15591091 19196723
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.7911408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 12.7914578162 12929590
MESH:D020149 Manganese Poisoning Estradiol 4.1819453300
MESH:D001523 Mental Disorders Clozapine 3.6616856516
MESH:D008607 Mental Retardation Toluene 3.559294310
MESH:D024821 Metabolic Syndrome X Clozapine 4.1719142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4916801185
MESH:D019957 Motor Skills Disorders Toluene 4.969294310
MESH:D009101 Multiple Myeloma Benzene 3.4617119195
MESH:D009102 Multiple Organ Failure Zymosan 4.9315834315 18160304 17724436 12130978 15213630 10479408 12879239 15259001 15241586 10890648
MESH:D009135 Muscular Diseases pirinixic acid 3.2216239165
MESH:D009203 Myocardial Infarction Cocaine 8.8918072171
MESH:D009203 Myocardial Infarction Genistein 8.8917141266
MESH:D009203 Myocardial Infarction pirinixic acid 8.8919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7912213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.8816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.8817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.8816411023
MESH:D009369 Neoplasms Diethylstilbestrol 7.5715313581
MESH:D009369 Neoplasms pirinixic acid 7.5717405874
MESH:D009369 Neoplasms Trichloroethylene 7.5711911487
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.4819196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4417289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0419348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 27.7516427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 27.7511399458
MESH:D009421 Nervous System Malformations Estradiol 27.7516427766 11399458
MESH:D009421 Nervous System Malformations Genistein 27.7516427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 27.7514600291
MESH:D009436 Neural Tube Defects Benzene 3.4815643154
MESH:D009765 Obesity Clozapine 4.4418515891 19142110
MESH:D009765 Obesity pirinixic acid 4.4420558911
MESH:D009784 Occupational Diseases Benzene 3.9315612468 15576619 17119257 16737584 15935809 15913788 17479406 17178637 15727169
MESH:D009845 Oligospermia methyl cellosolve 4.883987992
MESH:D010024 Osteoporosis Genistein 3.0719401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8116169203
MESH:D010049 Ovarian Diseases bisphenol A 4.6911985600
MESH:D010051 Ovarian Neoplasms Benzene 7.4112562636
MESH:D010051 Ovarian Neoplasms Estradiol 7.4119401270
MESH:D010051 Ovarian Neoplasms Genistein 7.4119005980
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9512520081
MESH:D010538 Peritonitis Zymosan 4.5918977430 18557954 14761945 15259001 19641140 17826846 15979727 19088179 18760300 17371808 11985352
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.8714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3815687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2818163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.9812371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 20.8710548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 20.8717184923
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 20.876499817 12530607 7974496
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.8711118676 11896295 11222880 11399792
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4815572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.6720887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.6720887781
MESH:D011471 Prostatic Neoplasms bisphenol A 1.9016740699
MESH:D011471 Prostatic Neoplasms Calcitriol 1.9012479363 16289102 16644109 18247401 15754350
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.9017136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 1.9016740699
MESH:D011471 Prostatic Neoplasms Genistein 1.9015378649 16925846 15256057
MESH:D011565 Psoriasis Cyclosporine 2.1216882103
MESH:D011618 Psychotic Disorders Clozapine 8.6715331141
MESH:D011618 Psychotic Disorders Cocaine 8.6716134406
MESH:D011629 Puberty, Precocious bisphenol A 4.4910548101
MESH:D015427 Reperfusion Injury pirinixic acid 2.2419058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5618990726
MESH:D012559 Schizophrenia Clozapine 2.7017667964 20168265 11763009 20107430 20521326 18855531 11151749 20452607 18806925 20580759 17123785 17726453 16141801 20521320 19369910
MESH:D012640 Seizures Cocaine 6.2010454489
MESH:D012640 Seizures Toluene 6.206431079 9294310
MESH:D018805 Sepsis Zymosan 4.4111441115
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9116192470
MESH:D013088 Spermatocele Diethylstilbestrol 4.4116709447 16002989
MESH:D013274 Stomach Neoplasms Benzene 2.4112562636
MESH:D019966 Substance-Related Disorders bisphenol A 3.6916045194 16684133
MESH:D013733 Testicular Diseases methyl cellosolve 9.976499806
MESH:D013733 Testicular Diseases Toluene 9.9710048760 10514026
MESH:D013953 Thymus Neoplasms Benzene 4.6610850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6012697716
MESH:D013978 Tibial Fractures Estradiol 4.3919048282
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 2.6616452187 16712894 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.7816175088
MESH:D014591 Uterine Diseases bisphenol A 12.8114652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.8114652134
MESH:D014594 Uterine Neoplasms Benzene 8.9212562636
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.9215809267 16690809
MESH:D014605 Uveitis Cyclosporine 10.981336536
MESH:D014605 Uveitis Zymosan 10.9811006244
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1516513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2912125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9515886252
MESH:D015430 Weight Gain Clozapine 4.2220521320 16141801 20564506 17502770 16402076 20107430
MESH:D015431 Weight Loss Clozapine 4.7817933447
MESH:D014985 Xerophthalmia Cyclosporine 4.1417120751
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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