AutismKB 2.0

Annotation Detail for RILPL2


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Basic Information Top
Gene Symbol:RILPL2 ( FLJ30380,FLJ32372,MGC7036 )
Gene Full Name: Rab interacting lysosomal protein-like 2
Band: 12q24.31
Quick LinksEntrez ID:196383; OMIM: NA; Uniprot ID:RIPL2_HUMAN; ENSEMBL ID: ENSG00000150977; HGNC ID: 28787
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of RILPL2 mRNAdecreases expression 18648102
D016572 Cyclosporine Cyclosporine results in decreased expression of RILPL2 mRNAdecreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.003712494
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.091440618 11289319
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.783581430 7296757
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.867296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.667505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.6612371664
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 9.1019486331 9022650
MESH:D002779 Cholestasis Cyclosporine 9.1019486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.5511906362 18759878 2524372 12868966 14531868 8156756 11298694 8970840
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.102952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0611289319 1440618 18692083 16192314 8291058 7440962 18289764 9022650 18648102 6679447 6482804 9328219 9653073
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005234 Fatty Liver Cyclosporine 3.4019224547
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.096705139
MESH:D005355 Fibrosis Cyclosporine 3.9012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 5.118708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.647505956
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.3115720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.196705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.7015034207
MESH:D006973 Hypertension Cyclosporine 2.2410903974
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.098074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.5115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.588314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.746582329
MESH:D007680 Kidney Neoplasms Cyclosporine 8.7412371664
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4715034207 9327722
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.80598648 6587162 1399818 3712494
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.8616801185
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.623581430
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.5117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7519348381 18481113
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.216679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.926482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.093988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.247296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.546228378
MESH:D011230 Precancerous Conditions Cyclosporine 3.6912371664
MESH:D011565 Psoriasis Cyclosporine 2.3516882103
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.743692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.266587162 3712494 1399818 6582329 7505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.428074119
MESH:D014605 Uveitis Cyclosporine 5.051336536
MESH:D014985 Xerophthalmia Cyclosporine 5.5117120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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