AutismKB 2.0

Annotation Detail for ZFC3H1


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Basic Information Top
Gene Symbol:ZFC3H1 ( CCDC131,DKFZp686A0722,KIAA0546,MGC23401,MGC90200,PSRC2 )
Gene Full Name: zinc finger, C3H1-type containing
Band: 12q21.1
Quick LinksEntrez ID:196441; OMIM: NA; Uniprot ID:ZC3H1_HUMAN; ENSEMBL ID: ENSG00000133858; HGNC ID: 28328
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic Arsenic affects the expression of ZFC3H1 mRNAaffects expression 18414638
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of ZFC3H1 mRNAincreases expression 18687144
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D018246 Adrenocortical Adenoma Arsenic 6.2817306315
MESH:D020261 Arsenic Poisoning Arsenic 2.9712569548 16835338 18414634 16251483
MESH:D050197 Atherosclerosis Arsenic 3.5112928151 19371607
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.8315504454 17687452
MESH:D006528 Carcinoma, Hepatocellular Arsenic 2.3217306315 16507464
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7918922899 17687452 15504454
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.5818640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.7715738583 17938729 19152805
MESH:D002340 Carotid Artery Diseases Arsenic 4.7818022660 16973168
MESH:D005534 Foot Diseases Arsenic 6.636392382
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.9617050553
MESH:D006973 Hypertension Arsenic 3.019931084 11953799 16076760
MESH:D006987 Hypesthesia Arsenic 6.6316093927
MESH:D007642 Keratosis Arsenic 5.8812749816 16930632
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.8517339181
MESH:D008107 Liver Diseases Arsenic 2.6311134558
MESH:D008113 Liver Neoplasms Arsenic 2.8216368122
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.7817365036
MESH:D008175 Lung Neoplasms Arsenic 2.2117976673 19168569 17306315
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.3316966607 16166281 18303189
MESH:D017202 Myocardial Ischemia Arsenic 4.3915371236
MESH:D009436 Neural Tube Defects Arsenic 3.7516620997
MESH:D020078 Neurogenic Inflammation Arsenic 4.9817056641
MESH:D010051 Ovarian Neoplasms Arsenic 2.8617306315
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.8516093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.8816905509 15371236 6392382
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.6610923243
MESH:D011471 Prostatic Neoplasms Arsenic 3.5416140617
MESH:D011507 Proteinuria Arsenic 4.6121343184
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1715814490 17322281 17365031 17975199
MESH:D012871 Skin Diseases Arsenic 2.8419834688 15952646 16702368 17548696 16353154 17938729 16759981 17050553 18709164 17453740 6392382
MESH:D012878 Skin Neoplasms Arsenic 3.1917029826 17050553 17976673 16251483 15504454 19538983
MESH:D001749 Urinary Bladder Neoplasms Arsenic 2.9611144890 18640142 17306315 15987713 17976673 19322015 19429237
MESH:D014652 Vascular Diseases Arsenic 5.6217056641
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018