Annotation Detail for LCTL
Basic Information Top
| Gene Symbol: | LCTL ( FLJ33279,KLG,KLPH ) |
|---|---|
| Gene Full Name: | lactase-like |
| Band: | 15q22.31 |
| Quick Links | Entrez ID:197021; OMIM: NA; Uniprot ID:LCTL_HUMAN; ENSEMBL ID: ENSG00000188501; HGNC ID: 15583 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000638 | Amiodarone | Amiodarone results in increased expression of LCTL mRNA | increases expression | 19774075 |
| D001104 | Arbutin | Arbutin results in decreased expression of LCTL mRNA | decreases expression | 17103032 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 4.31 | 18218290 18057881 20041841 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 4.27 | 19698954 18651412 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 4.45 | 19483382 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 3.02 | 15710769 19225199 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 5.97 | 18974383 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 2.49 | 18218290 15265979 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 4.07 | 14986274 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 4.51 | 15265979 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 4.42 | 8137927 9751232 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 5.28 | 18020914 17991464 | |
| MESH:D008064 | Lipidoses | Amiodarone | 3.85 | 17567588 15342952 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 3.96 | 11989578 15350150 17391786 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 3.68 | 12587719 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 5.55 | 18516814 | |
| MESH:D009181 | Mycoses | Amiodarone | 5.97 | 12754197 17974566 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.99 | 12490602 12832656 11597910 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 5.97 | 18724381 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 3.86 | 18087811 | |
| MESH:D013610 | Tachycardia | Amiodarone | 4.96 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 4.86 | 19225199 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 5.83 | 19731979 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 5.62 | 18020914 19584973 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 5.08 | 11989578 17467628 |
| No data |
| Drugbank ID | Action | Drug Name | Description |
|---|---|---|---|
| DB02185 | - | 2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One | |
| DB02379 | - | Beta-D-Glucose | Sweetening Agents |
| DB02471 | - | Nojirimycine Tetrazole | |
| DB03430 | - | (2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile | |
| DB08430 | - | PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE |
| No data |
| No data |
| No data |