AutismKB 2.0

Annotation Detail for ELAVL4


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Basic Information Top
Gene Symbol:ELAVL4 ( HUD,PNEM )
Gene Full Name: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
Band: 1p33-p32.3
Quick LinksEntrez ID:1996; OMIM: 168360; Uniprot ID:ELAV4_HUMAN; ENSEMBL ID: ENSG00000162374; HGNC ID: 3315
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1709Parkinson disease
2151Neuroblastoma
2257Hemolytic-Uremic syndrome
No data
No data
Desease Name
Neuropathy, paraneoplastic sensory
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ELAVL4 mRNAaffects expression 16483693
C020771 methylmercury hydroxide methylmercury hydroxide results in increased expression of ELAVL4 mRNAincreases expression 20493249
D008942 Mitoxantrone ELAVL4 mRNA affects the susceptibility to Mitoxantroneaffects response to substance 16044152
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in increased expression of ELAVL4 proteinincreases expression 19474218
C017947 sodium arsenite sodium arsenite affects the expression of ELAVL4 mRNAaffects expression 19590694
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.3115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.5117306315 16712894
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 2.0017306315 15276417 16507464
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4618572023
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.2220056578 19524636
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.2216452187
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 4.4717162496
MESH:D006331 Heart Diseases Mitoxantrone 4.3916019553
MESH:D006689 Hodgkin Disease sodium arsenite 3.4712676792
MESH:D007248 Infertility, Male sodium arsenite 3.2115346721 12646999
MESH:D007674 Kidney Diseases sodium arsenite 2.9820008137
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.9118172266
MESH:D008113 Liver Neoplasms sodium arsenite 2.4715276417 16712894
MESH:D008171 Lung Diseases sodium arsenite 3.4019095001
MESH:D008175 Lung Neoplasms sodium arsenite 1.9016712894 19931552 17306315 17077188 15276417
MESH:D008545 Melanoma sodium arsenite 2.0716487513 19082730
MESH:D009369 Neoplasms Mitoxantrone 5.9916640825
MESH:D009369 Neoplasms sodium arsenite 5.9911559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.1520056578
MESH:D009436 Neural Tube Defects sodium arsenite 3.3612854658
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.5217306315 15276417
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2416039940
MESH:D012878 Skin Neoplasms sodium arsenite 2.8419524636 18572023
MESH:D016135 Spinal Dysraphism sodium arsenite 4.0712854658
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 2.6216452187 16712894 17306315 11723127
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.1111813266
MESH:D014652 Vascular Diseases sodium arsenite 4.9617056641
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018