AutismKB 2.0

Annotation Detail for PLD5


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Basic Information Top
Gene Symbol:PLD5 ( FLJ40773,MGC120565,MGC120566,MGC120567,PLDC )
Gene Full Name: phospholipase D family, member 5
Band: 1q43
Quick LinksEntrez ID:200150; OMIM: NA; Uniprot ID:PLD5_HUMAN; ENSEMBL ID: ENSG00000180287; HGNC ID: 26879
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D004958 Estradiol Estradiol results in increased expression of PLD5 mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Estradiol 2.1911473722
MESH:D001321 Autistic Disorder marker/mechanism 20663923
MESH:D001943 Breast Neoplasms Estradiol 2.0917261762 17018787 16675129 17289903 19861407 14630087 12948864 18497071
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.5516111702
MESH:D006528 Carcinoma, Hepatocellular Estradiol 1.8016924424
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.1318566989
MESH:D003928 Diabetic Nephropathies Estradiol 3.9419279558
MESH:D016889 Endometrial Neoplasms Estradiol 3.3118566989 19148513 11473722
MESH:D006558 Herpes Genitalis Estradiol 6.4515709030
MESH:D019584 Hot Flashes Estradiol 5.1717088409
MESH:D007333 Insulin Resistance Estradiol 3.2916393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.8515618244
MESH:D007680 Kidney Neoplasms Estradiol 3.4615610895
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6914659978 14716833
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.8716891317 11408345 17203775 11807958
MESH:D020149 Manganese Poisoning Estradiol 5.9019453300
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.7116810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.8217289903
MESH:D009421 Nervous System Malformations Estradiol 4.4416427766 11399458
MESH:D010051 Ovarian Neoplasms Estradiol 2.3419401270
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.5120887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.0016740699
MESH:D013978 Tibial Fractures Estradiol 6.1019048282
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018