AutismKB 2.0

Annotation Detail for CRTC2


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Basic Information Top
Gene Symbol:CRTC2 ( TORC2 )
Gene Full Name: CREB regulated transcription coactivator 2
Band: 1q21.3
Quick LinksEntrez ID:200186; OMIM: 608972; Uniprot ID:CRTC2_HUMAN; ENSEMBL ID: ENSG00000160741; HGNC ID: 27301
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200061LKB1 signaling events
No data
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Related Diseases/Disorders Top
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Desease IDDesease Name
1904Diabetes mellitus
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CRTC2 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6916109766 19739265 18071297 19420014 11461765 15619225 16227642 12540782 11834606 12153990 19416960 19164858 14986274 11529661 12958197 10663392 16177239 11287661 12705907 19923254 19085960 11743745 16081117 18713872 16781746 10915739 14725611 14550746 11421492 11739529 17562736 2444490 19370779 17906064 15968718 12594235 16393943 12392966 17522070 10774834 16485898
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4712587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7212969438 16610002 19014921 12587719 19460945 11587558 16611625 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8117185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
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Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018