AutismKB 2.0

Annotation Detail for APOBEC3F


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Basic Information Top
Gene Symbol:APOBEC3F ( ARP8,BK150C2.4.MRNA,KA6,MGC74891 )
Gene Full Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
Band: 22q13.1
Quick LinksEntrez ID:200316; OMIM: 608993; Uniprot ID:ABC3F_HUMAN; ENSEMBL ID: ENSG00000128394; HGNC ID: 17356
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1712Yersinia infection
1809HIV infection
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001374 Azacitidine Azacitidine results in increased expression of APOBEC3F mRNAincreases expression 19194470
C014347 decitabine decitabine results in increased expression of APOBEC3F mRNAincreases expression 19194470
D004958 Estradiol Estradiol results in increased expression of APOBEC3F mRNAincreases expression 19139166
D018038 Sodium Selenite Sodium Selenite results in decreased expression of APOBEC3F mRNAdecreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Estradiol 2.1711473722
MESH:D001943 Breast Neoplasms decitabine 2.2219208741 18320071
MESH:D001943 Breast Neoplasms Estradiol 2.2216675129 19861407 12948864 17261762 18497071 17289903 17018787 14630087
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 5.0916111702
MESH:D006528 Carcinoma, Hepatocellular Estradiol 1.7916924424
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6819215824
MESH:D002471 Cell Transformation, Neoplastic Estradiol 3.0318566989
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D003110 Colonic Neoplasms decitabine 2.3817616700
MESH:D015179 Colorectal Neoplasms Azacitidine 2.9719934284
MESH:D015179 Colorectal Neoplasms decitabine 2.9718981723
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D003928 Diabetic Nephropathies Estradiol 3.7819279558
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3615131321
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.8419294695
MESH:D016889 Endometrial Neoplasms Estradiol 3.2218566989 11473722 19148513
MESH:D006258 Head and Neck Neoplasms decitabine 3.7419215824
MESH:D006558 Herpes Genitalis Estradiol 5.7615709030
MESH:D019584 Hot Flashes Estradiol 4.4717088409
MESH:D007248 Infertility, Male decitabine 3.4517581917
MESH:D007333 Insulin Resistance Estradiol 8.2516393666 16627594
MESH:D007333 Insulin Resistance Sodium Selenite 8.2514714311
MESH:D007674 Kidney Diseases Estradiol 2.7815618244
MESH:D007680 Kidney Neoplasms Estradiol 3.3215610895
MESH:D007938 Leukemia Azacitidine 7.3319148494
MESH:D007938 Leukemia decitabine 7.3318980019 19235587
MESH:D007951 Leukemia, Myeloid Azacitidine 11.3519077051
MESH:D007951 Leukemia, Myeloid decitabine 11.3518454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 4.4917596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.4917679729 18460780 18206229 19387464 19010910 18704418
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.1918055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.6519299654
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 1.6814716833 14659978
MESH:D008175 Lung Neoplasms Azacitidine 2.7321224363
MESH:D008223 Lymphoma decitabine 3.6919470736
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.7911408345 17203775 16891317 11807958
MESH:D020149 Manganese Poisoning Estradiol 5.2119453300
MESH:D008545 Melanoma decitabine 2.2816505122 17785578
MESH:D009006 Monosomy Azacitidine 6.8119299654
MESH:D009101 Multiple Myeloma Azacitidine 8.6319549372 18443271
MESH:D009101 Multiple Myeloma decitabine 8.6318172295
MESH:D009190 Myelodysplastic Syndromes Azacitidine 8.4917596541 19805378 18720364 17611569
MESH:D009190 Myelodysplastic Syndromes decitabine 8.4919010910 18608210 16882708 19157545
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.5916810080
MESH:D009369 Neoplasms decitabine 2.8717925555 19116145 19470736
MESH:D009389 Neovascularization, Pathologic Estradiol 4.3617289903
MESH:D009421 Nervous System Malformations Estradiol 4.1616427766 11399458
MESH:D010051 Ovarian Neoplasms decitabine 5.2519331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 5.2519401270
MESH:D010190 Pancreatic Neoplasms decitabine 2.8719294695
MESH:D055728 Primary Myelofibrosis decitabine 5.2917616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.3120887781
MESH:D011471 Prostatic Neoplasms Azacitidine 2.6318324645
MESH:D011471 Prostatic Neoplasms Estradiol 2.6316740699
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.6318760546
MESH:D012208 Rhabdomyosarcoma decitabine 4.8719155313
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013964 Thyroid Neoplasms decitabine 3.6317967635
MESH:D013978 Tibial Fractures Estradiol 5.4119048282
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.8419087683 17616700
MESH:D014604 Uveal Neoplasms decitabine 5.6417785578
Pathway ID Pathway Name
REACT:6185 HIV Infection
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24896
    • Releated gene ID Related gene Name
    PA24896APOBEC3F
    No data
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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