AutismKB 2.0

Annotation Detail for EMP1


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Basic Information Top
Gene Symbol:EMP1 ( CL-20,EMP-1,TMP )
Gene Full Name: epithelial membrane protein 1
Band: 12p13.1
Quick LinksEntrez ID:2012; OMIM: 602333; Uniprot ID:EMP1_HUMAN; ENSEMBL ID: ENSG00000134531; HGNC ID: 3333
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of EMP1 mRNAincreases expression 20713471
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of EMP1 mRNAdecreases expression 16788091
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in increased expression of EMP1 mRNAincreases expression 15982314
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of EMP1 proteinaffects expression 20106945
C430898 AGN 194204 AGN 194204 results in decreased expression of EMP1 mRNAdecreases expression 16339527
C103303 alitretinoin alitretinoin results in increased expression of EMP1 mRNAincreases expression 15982314
D000643 Ammonium Chloride Ammonium Chloride affects the expression of EMP1 mRNAaffects expression 16483693
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of EMP1 mRNAincreases expression 18687144
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP1 mRNAaffects cotreatment|increases expression 17639512
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EMP1 mRNAaffects cotreatment|increases expression 18164116
D016572 Cyclosporine Cyclosporine results in increased expression of EMP1 mRNAincreases expression 20106945
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNAaffects cotreatment|decreases expression 16054899
D003907 Dexamethasone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D004041 Dietary Fats Dietary Fats results in increased expression of EMP1 mRNAincreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EMP1 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of EMP1 mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of EMP1 mRNAincreases expression 17010207
D004958 Estradiol ESR1 protein affects the reaction [Estradiol results in decreased expression of EMP1 mRNA]affects reaction|decreases expression 14699072
D004958 Estradiol Estradiol results in increased expression of EMP1 mRNAincreases expression 17010207
C010176 halofuginone halofuginone results in increased expression of EMP1 mRNAincreases expression 17180598
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of EMP1 mRNAincreases expression 15046208
D007501 Iron Iron deficiency results in increased expression of EMP1 mRNAincreases expression 20368581
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNAaffects cotreatment|decreases expression 16054899
D015056 1-Methyl-3-isobutylxanthine [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of EMP1 mRNAincreases expression 20713471
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of EMP1 mRNAincreases expression 12634122
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of EMP1 mRNAdecreases expression 17616710
C474055 octylphenol octylphenol results in increased expression of EMP1 mRNAincreases expression 17010207
C041786 palm oil palm oil results in increased expression of EMP1 mRNAincreases expression 18042831
C006253 pirinixic acid pirinixic acid results in increased expression of EMP1 mRNAincreases expression 17426115
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP1 mRNAaffects cotreatment|increases expression 17639512
D020849 Raloxifene ESR1 protein affects the reaction [Raloxifene results in decreased expression of EMP1 mRNA]affects reaction|decreases expression 14699072
D015474 Isotretinoin Isotretinoin results in increased expression of EMP1 mRNAincreases expression 15982314
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNAaffects cotreatment|decreases expression 16054899
C089730 rosiglitazone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
C009277 sodium arsenate sodium arsenate results in decreased expression of EMP1 mRNAdecreases expression 12727804
C017947 sodium arsenite sodium arsenite results in decreased expression of EMP1 mRNAdecreases expression 12727804
D014284 Triiodothyronine Triiodothyronine results in increased expression of EMP1 mRNAincreases expression 19228888
D013629 Tamoxifen Tamoxifen affects the expression of EMP1 mRNAaffects expression 14699072
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EMP1 mRNAincreases expression 16704738
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] results in increased expression of EMP1 mRNAaffects cotreatment|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EMP1 mRNA]affects cotreatment|decreases expression|decreases reaction 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EMP1 mRNAincreases expression 16054899
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in increased expression of EMP1 mRNAincreases expression 17951470
D014212 Tretinoin Tretinoin metabolite results in increased expression of EMP1 mRNAincreases expression 15982314
D014212 Tretinoin Tretinoin results in increased expression of EMP1 mRNAincreases expression 15982314
16249480
C025643 vinclozolin vinclozolin affects the expression of EMP1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1514745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 7.4018769834
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.4011752688 14514962 15322242
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.6318769834
MESH:D000138 Acidosis Ammonium Chloride 9.4118287403
MESH:D000138 Acidosis Hydrochloric Acid 9.4115920416 19262391 16144966 20872349 11574821 12771618
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.3917183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.4120597076
MESH:D017486 Acneiform Eruptions Isotretinoin 5.8816232082
MESH:D000152 Acne Vulgaris Isotretinoin 5.0818769834 16185265
MESH:D055371 Acute Lung Injury Hydrochloric Acid 8.1111953099 16759491 19060228 15970105 19760209 11850527 19094174
MESH:D055371 Acute Lung Injury pirinixic acid 8.1118653653
MESH:D000230 Adenocarcinoma Estradiol 2.0011473722
MESH:D000236 Adenoma beta-Naphthoflavone 9.9619389873
MESH:D000236 Adenoma Diethylnitrosamine 9.966695378 10737359
MESH:D000236 Adenoma Methylcholanthrene 9.966695378 10545420
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.9916434500 19061943 19052882 17620307 17162532 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 14.9916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.9916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3015276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5016712894 17306315
MESH:D000419 Albuminuria Raloxifene 4.2217451421 17308373
MESH:D000505 Alopecia Tretinoin 3.3015955085
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.2616640825
MESH:D000544 Alzheimer Disease Iron 6.2216640825 16563566
MESH:D000544 Alzheimer Disease Raloxifene 6.2215800139
MESH:D000544 Alzheimer Disease rosiglitazone 6.2219621015
MESH:D000686 Amyloidosis Diethylstilbestrol 4.1115469931
MESH:D000740 Anemia Iron 7.7916434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.7911748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.8917084956
MESH:D018798 Anemia, Iron-Deficiency Iron 4.3117375513 16569441 17163184 17162259 17147795
MESH:D000756 Anemia, Sideroblastic Iron 4.4616910769
MESH:D000860 Anoxia Hydrochloric Acid 4.9115090967
MESH:D001008 Anxiety Disorders vinclozolin 3.3319015723
MESH:D001145 Arrhythmias, Cardiac Iron 4.0316604332
MESH:D001161 Arteriosclerosis Dietary Fats 3.5115238619
MESH:D001169 Arthritis, Experimental Dexamethasone 6.7017659584
MESH:D001169 Arthritis, Experimental Tretinoin 6.7016412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1716292516
MESH:D001249 Asthma Tretinoin 2.2216456186
MESH:D001260 Ataxia Telangiectasia Iron 11.7915336622
MESH:D001260 Ataxia Telangiectasia Quercetin 11.7915336622
MESH:D050197 Atherosclerosis Iron 6.3316632123 16640825
MESH:D050197 Atherosclerosis Methylcholanthrene 6.3311922910
MESH:D001321 Autistic Disorder Iron 2.8317352947
MESH:D001327 Autoimmune Diseases Quercetin 4.0219761891
MESH:D001424 Bacterial Infections Iron 4.8016640825
MESH:D001471 Barrett Esophagus Tretinoin 4.0316935849
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 19.1115920416
MESH:D001778 Blood Coagulation Disorders pirinixic acid 19.1119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.1112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 19.1116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5115746008
MESH:D001930 Brain Injuries Raloxifene 4.0916580743
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 10.4811921183
MESH:D001943 Breast Neoplasms alitretinoin 10.4816344269
MESH:D001943 Breast Neoplasms Ascorbic Acid 10.4816443354
MESH:D001943 Breast Neoplasms Dietary Fats 10.4820435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 10.4817474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 10.4817129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 10.4812948864 17018787 17289903 16675129 19861407 14630087 17261762 18497071
MESH:D001943 Breast Neoplasms Methylcholanthrene 10.4817474063
MESH:D001943 Breast Neoplasms Quercetin 10.4818628248
MESH:D001943 Breast Neoplasms Raloxifene 10.4817242785 15572757 16912660 17893378 16837676 15758505 17049068 17595753 17440819 17952589 17261762 15775269
MESH:D001943 Breast Neoplasms Tamoxifen 10.4819059307 18629630 21138602 17893378 19289846 20544844 19288272 19189210 19410462 19155303 17440819 15668708 20859285 19189212 18425577 19487384 19244106 19115204 16273361 19142967 16873071 19084267 20390343 16202921 19103187 18815881 21152245 17049068 17261762 15565566 19200415 18855134 20065188 18351453 20135344 19221464 11161223 19011961 20005174 18997820 19066611 16818667 18984771 18821012 17242785
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.4820435547
MESH:D001943 Breast Neoplasms Tretinoin 10.4816166294 16443354 16873071
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 4.2812378975
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.0715578804
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2016813970
MESH:D002105 Cadmium Poisoning Quercetin 5.1416962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0716111702
MESH:D002277 Carcinoma Methylcholanthrene 7.3010545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.3016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1219066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7616168501
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 15.6012907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 15.6020512989 20727157 16807293 19919837 18971187 16569478 19418558 18210153 20432363 19701751 19107877 20514400 11831363 16935385 16698587 20214788 10672840 18788625 10737359 3084413 19394651 19208518 17162532 16878318 19335982 18393292 18665156 16502159 20084675 19539802 18691550 16328049 17055752 19052882 19822196 20524982 16540662 18506893 16779866 17138121 18978308 16288022 20935162 17978847 19383236 19171122 20101231 20007298 3581430 17761372 16681979 17173139 17428255 19519916 18494052 18785209 16830150 21159647 18056438
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 15.6016924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 15.6016924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 15.6019519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 15.6015276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.6016924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 15.601917145
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5717234771
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 6.9411237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 6.9418572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 6.9416096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.3717572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.3717572228
MESH:D006332 Cardiomegaly Quercetin 6.0519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.0518670907 18850075 16120746
MESH:D009202 Cardiomyopathies Iron 3.7816640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.3216604332
MESH:D002318 Cardiovascular Diseases Raloxifene 3.1715775269
MESH:D002386 Cataract Tretinoin 2.8617460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 22.8212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 22.8217174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 22.8218566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 22.8216192471
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 22.822727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 22.8219524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2016129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.2319052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.2316835633
MESH:D002779 Cholestasis Cyclosporine 6.7919486331
MESH:D002779 Cholestasis pirinixic acid 6.7919176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.1812621046 8697196 16354765 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 5.189407595
MESH:D003072 Cognition Disorders Raloxifene 4.2315800139
MESH:D003092 Colitis Tretinoin 3.3217035595
MESH:D003110 Colonic Neoplasms Dexamethasone 5.5015824018
MESH:D003110 Colonic Neoplasms Iron 5.5016640825
MESH:D003110 Colonic Neoplasms Quercetin 5.5011134977 19440933 19056647 17148506 16640504 17191121 15741050
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818852136 18095365
MESH:D003139 Common Cold Ascorbic Acid 5.0717323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7317141729 14669216
MESH:D019465 Craniofacial Abnormalities Dexamethasone 6.8117728286
MESH:D019465 Craniofacial Abnormalities Isotretinoin 6.819879862 18769834
MESH:D019465 Craniofacial Abnormalities sodium arsenate 6.8110525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.8115322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.8114991402 17551590 9224671 10589399 9142499 16925845 9664655 9211117 9125849 8800419
MESH:D003456 Cryptorchidism Diethylstilbestrol 10.1216002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 10.1214966744
MESH:D003556 Cystitis Hydrochloric Acid 5.0719279288 12599022 20719367 12853844
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.4117714534
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9819031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.8317474826
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.0412438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2418249437
MESH:D003920 Diabetes Mellitus Iron 8.5716640825 16604332
MESH:D003920 Diabetes Mellitus rosiglitazone 8.5717446233
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.4219496084
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.2316506275
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 12.4716506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 12.4720387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 12.4716506275
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 12.4712642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 12.4717107852
MESH:D003928 Diabetic Nephropathies Estradiol 13.1119279558
MESH:D003928 Diabetic Nephropathies Raloxifene 13.1117308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 13.1119279558
MESH:D003967 Diarrhea Dexamethasone 3.337237001
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.5719107877
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 5.5718186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.5720420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4711462148
MESH:D050171 Dyslipidemias Dietary Fats 3.1718367378
MESH:C538011 Eales disease Ascorbic Acid 5.079068938
MESH:D004485 Eczema Dexamethasone 4.0912438553
MESH:D004487 Edema Dexamethasone 17.9619703484
MESH:D004487 Edema pirinixic acid 17.9612083418
MESH:D004487 Edema Raloxifene 17.9615860553
MESH:D004487 Edema rosiglitazone 17.9612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 17.9612711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.6115322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.6118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 8.0015845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.0019031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.3016402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 15.6416804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 15.6419148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tamoxifen 15.6419155303 16202921 20544844 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 15.6416569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.689294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7116302075
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.4019566590
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 2.6715150132 16805852 15547721 15878914 16704527 15264214 15623463 16510608 15547733
MESH:D004941 Esophagitis Hydrochloric Acid 5.6012928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.6120516732 14621274 11346197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.8611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.8616938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 37.1719224547
MESH:D005234 Fatty Liver Dietary Fats 37.1717967931 18296743 19551842 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 37.1720387270 21071580
MESH:D005234 Fatty Liver Iron 37.1716640825
MESH:D005234 Fatty Liver pirinixic acid 37.1720131406 19236843
MESH:D005234 Fatty Liver Raloxifene 37.1717473493
MESH:D005234 Fatty Liver rosiglitazone 37.1719196556
MESH:D005234 Fatty Liver Tamoxifen 37.1714986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.4015751030 16513791 16534752 16611131 16002989
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.4016709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0711858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1314745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.7919069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.5514633661 10962813
MESH:D005355 Fibrosis Cyclosporine 29.5112639820 12168785
MESH:D005355 Fibrosis Dietary Fats 29.5118296743
MESH:D005355 Fibrosis Hydrochloric Acid 29.5118497604
MESH:D005355 Fibrosis Quercetin 29.5119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 29.5120067830
MESH:D005355 Fibrosis Tretinoin 29.5117994277
MESH:D005621 Friedreich Ataxia Iron 5.0416640825 16604332
MESH:D005739 Gas Poisoning Hydrochloric Acid 5.0712378975
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.9519957777 12212954 20545468 19951613 20516732 20616304
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5416973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.9016417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 11.5016452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 11.5016452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.828708960
MESH:D005909 Glioblastoma Quercetin 6.4019804834
MESH:D005909 Glioblastoma Tretinoin 6.4017312396
MESH:D005910 Glioma Quercetin 2.8917643826
MESH:D018149 Glucose Intolerance sodium arsenate 4.7219446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.9216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7616084493
MESH:D006356 Heartburn Hydrochloric Acid 5.4019566590
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 9.9916080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.9910048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.9914991402 9664655
MESH:D006331 Heart Diseases Raloxifene 3.2611110106
MESH:D006333 Heart Failure pirinixic acid 2.2920558911
MESH:D006432 Hemochromatosis Iron 4.2016604332 16640825 17053826 17236123 16574947 17255318
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9811000095
MESH:D006486 Hemosiderosis Iron 4.8116604332
MESH:D006525 Hepatitis, Viral, Human Iron 5.0716640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.5517182432
MESH:D006529 Hepatomegaly Iron 12.2716890145
MESH:D006529 Hepatomegaly pirinixic acid 12.2718467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.2715340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 5.7616490937 16863852
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.767520565
MESH:D006558 Herpes Genitalis Estradiol 4.6315709030
MESH:D015658 HIV Infections Iron 3.4616597321
MESH:D006689 Hodgkin Disease sodium arsenite 2.8312676792
MESH:D019584 Hot Flashes Estradiol 3.3517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6415340226 16959395 8697196 16354765 18606429
MESH:D006930 Hyperalgesia rosiglitazone 7.0512083418
MESH:D006930 Hyperalgesia Tretinoin 7.0516870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2421332399
MESH:D006940 Hyperemia Hydrochloric Acid 5.2612646421
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1816778211
MESH:D006943 Hyperglycemia pirinixic acid 8.1120558911
MESH:D006943 Hyperglycemia Quercetin 8.1111834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.2621332399
MESH:D006965 Hyperplasia Diethylstilbestrol 10.0312960047 14722030
MESH:D006965 Hyperplasia halofuginone 10.0311874485
MESH:D006973 Hypertension Cyclosporine 14.6710903974
MESH:D006973 Hypertension Dexamethasone 14.6717042910
MESH:D006973 Hypertension Quercetin 14.6718356687
MESH:D006973 Hypertension Raloxifene 14.6715787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 14.6718850075 18670907
MESH:D006975 Hypertension, Portal Hydrochloric Acid 4.9616984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.1719262391
MESH:D007006 Hypogonadism Iron 4.1216640825
MESH:D007021 Hypospadias Diethylstilbestrol 4.1916002989
MESH:D007022 Hypotension Hydrochloric Acid 4.4011574821
MESH:D007037 Hypothyroidism Iron 4.7016640825
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.0418306037
MESH:D007246 Infertility Diethylstilbestrol 3.9815036965
MESH:D007248 Infertility, Male sodium arsenite 5.9715346721 12646999
MESH:D007248 Infertility, Male vinclozolin 5.9716467254
MESH:D007249 Inflammation Dexamethasone 20.9711099482 8960868
MESH:D007249 Inflammation Dietary Fats 20.9720412841
MESH:D007249 Inflammation Diethylnitrosamine 20.9718785209
MESH:D007249 Inflammation Hydrochloric Acid 20.9711574821
MESH:D007249 Inflammation rosiglitazone 20.9712083418
MESH:D007249 Inflammation Tamoxifen 20.9719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.9712200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.1116624496
MESH:D007333 Insulin Resistance Dietary Fats 15.5318457598 11836018
MESH:D007333 Insulin Resistance Estradiol 15.5316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 15.5316306350
MESH:D007333 Insulin Resistance rosiglitazone 15.5316306350
MESH:D007410 Intestinal Diseases Hydrochloric Acid 8.8411574821
MESH:D007410 Intestinal Diseases Tretinoin 8.8417994277
MESH:D019189 Iron Metabolism Disorders Iron 4.6717163184
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.7616580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.7615992940 17551590
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.0418306037
MESH:D007627 Keloid Quercetin 4.5717086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0415604871
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.2416144296
MESH:D007674 Kidney Diseases Cyclosporine 12.5410903974 18776723 8314463
MESH:D007674 Kidney Diseases Estradiol 12.5415618244
MESH:D007674 Kidney Diseases Quercetin 12.5416962696
MESH:D007674 Kidney Diseases sodium arsenite 12.5420008137
MESH:D007680 Kidney Neoplasms Cyclosporine 15.1512371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 15.1515003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 15.1515610895
MESH:D007680 Kidney Neoplasms Tamoxifen 15.1518625569
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 5.9616498863
MESH:D007826 Laryngismus Hydrochloric Acid 5.9611510729
MESH:D007859 Learning Disorders Diethylstilbestrol 3.6817184923
MESH:D007889 Leiomyoma Raloxifene 4.1316973256
MESH:D007938 Leukemia Quercetin 5.7817468513
MESH:D007938 Leukemia Tretinoin 5.7817143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3519285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0116294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.8917339181 9834237 19035177 17712046 19029980 17368321 16891316 17217047 16788101 16140955 19075265 17506722 17649720 12679006 17107899 16766008 19642359 16331271 16935935 15748426 19225113 17301526 17361223 16823087 17294898
MESH:D020961 Lewy Body Disease Iron 5.0416563566
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3416417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.039224671
MESH:D008064 Lipidoses Tamoxifen 2.8715342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 18.4118296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 18.4118407596 20032147 19638242 18522880 18665156
MESH:D008103 Liver Cirrhosis halofuginone 18.4117180598
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 18.4116984587
MESH:D008103 Liver Cirrhosis Iron 18.4116640825
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 14.5416718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.5414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 14.5411172339 12175628 18458672 16489207 14739098
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 14.5415474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 14.5412741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 14.5415980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 14.5418564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.5412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 14.5416248980 18397230
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0017034775
MESH:D008108 Liver Diseases, Alcoholic Iron 4.6217207112 16737972
MESH:D008113 Liver Neoplasms Aflatoxin B1 30.9115890375 2125692 9163691 18177683
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 30.9119389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 30.9118648771 20501860 19690152 19090486 18977376 15885732 19294768 2862719 18644402 20583210 15175105 20405173 19426721 19073162 19254457 9163691 18754104 21167192 20101389 21071580 16942905 19256749 19812893 10737359 20137499 20118626 21278145 20492335 20452335 19850985 19427195 19255062 12112319 2422723 19638242 19996281 19499222 20434301 12771043 19833225 19642983 18978307 21047994 19551842
MESH:D008113 Liver Neoplasms Diethylstilbestrol 30.9116712894 15890375
MESH:D008113 Liver Neoplasms Iron 30.9116640825 20302851
MESH:D008113 Liver Neoplasms pirinixic acid 30.9120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 30.9118980244
MESH:D008113 Liver Neoplasms sodium arsenite 30.9115276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 30.9116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 30.9116984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 24.448603461
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 24.4418544905
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 24.4418164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 24.4421159647 19009564 9362446 16267830 3124819 19539802 18282651 18775883 2563599 18164116 17174075 18253720 17854601 18544905 19004024 18079962 17942915 19126423 18093689 19519916 18308698 16842330
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 24.441399818 598648
MESH:D008114 Liver Neoplasms, Experimental Quercetin 24.4419519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 24.4412151625
MESH:D008171 Lung Diseases Ascorbic Acid 11.0516863852
MESH:D008171 Lung Diseases Hydrochloric Acid 11.0516784557
MESH:D008171 Lung Diseases sodium arsenite 11.0519095001
MESH:D055370 Lung Injury Asbestos, Crocidolite 8.3117365036
MESH:D055370 Lung Injury Hydrochloric Acid 8.3120597076 18573544 21114838 19644408 17627322 18339021 16129981 15090967 19262391 21311175 15044056 11395602 18497604 15607125
MESH:D008175 Lung Neoplasms Aflatoxin B1 21.7914755239
MESH:D008175 Lung Neoplasms alitretinoin 21.7916413115
MESH:D008175 Lung Neoplasms Ascorbic Acid 21.7916401635
MESH:D008175 Lung Neoplasms Dexamethasone 21.7915824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 21.7920512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Iron 21.7916640825
MESH:D008175 Lung Neoplasms Isotretinoin 21.7915899809
MESH:D008175 Lung Neoplasms Methylcholanthrene 21.7916271038 16337739 11893704 20970405 21163286 10545420 20512841 1399818 17909032 9230183 6695378 15390079 7750092
MESH:D008175 Lung Neoplasms Quercetin 21.7916280456
MESH:D008175 Lung Neoplasms sodium arsenite 21.7917077188 19931552 17306315 15276417 16712894
MESH:D008175 Lung Neoplasms Tamoxifen 21.7918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 21.7911884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.7515166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.1915700306
MESH:D008268 Macular Degeneration Iron 3.7616640825
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1116002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3719428831
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 12.2311921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.2311807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 12.2316827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 12.2311731420 19196722 14580682 19196723 16827153
MESH:D020149 Manganese Poisoning Estradiol 11.3119453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.3119453300
MESH:D008527 Medulloblastoma Tretinoin 2.6217453147
MESH:D008545 Melanoma Isotretinoin 6.6617237267
MESH:D008545 Melanoma sodium arsenite 6.6619082730 16487513
MESH:D008545 Melanoma Tamoxifen 6.6619393235 12393984
MESH:D008545 Melanoma Tretinoin 6.6616752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.7915990972
MESH:D008591 Meningomyelocele Tretinoin 4.0416940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0216166281 18303189 16966607
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.0617261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3916801185
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.4917671175
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.1515863610
MESH:D009101 Multiple Myeloma Dexamethasone 6.6215867202 15744524 16118317
MESH:D009101 Multiple Myeloma Raloxifene 6.6216497877
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.2717086897
MESH:D009135 Muscular Diseases pirinixic acid 3.1216239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.5018186108
MESH:D009181 Mycoses Iron 5.0716640825
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.779809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.7717596541
MESH:D009203 Myocardial Infarction Hydrochloric Acid 8.6018534312
MESH:D009203 Myocardial Infarction pirinixic acid 8.6019151258
MESH:D009203 Myocardial Infarction Quercetin 8.6019595682
MESH:D017202 Myocardial Ischemia Iron 8.1416604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.1412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 17.8516810080
MESH:D015428 Myocardial Reperfusion Injury Iron 17.8516604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 17.8516411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 17.8519207477
MESH:D009232 Myxoma Raloxifene 5.1516343187
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.173581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.1719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3819410462
MESH:D009369 Neoplasms alitretinoin 17.1516946489
MESH:D009369 Neoplasms Diethylstilbestrol 17.1515313581
MESH:D009369 Neoplasms pirinixic acid 17.1517405874
MESH:D009369 Neoplasms Quercetin 17.1515185748
MESH:D009369 Neoplasms sodium arsenite 17.1511559025
MESH:D009369 Neoplasms Tretinoin 17.1516946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.2920056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6019196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3417289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.3919348381 18481113
MESH:D009404 Nephrotic Syndrome Iron 8.3917178036
MESH:D009421 Nervous System Malformations Diethylstilbestrol 20.3711399458
MESH:D009421 Nervous System Malformations Estradiol 20.3711399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 20.3714600291
MESH:D009421 Nervous System Malformations Tretinoin 20.379125849
MESH:D009436 Neural Tube Defects sodium arsenate 10.7611749123 19446573 18186108 10525206
MESH:D009436 Neural Tube Defects sodium arsenite 10.7612854658
MESH:D009436 Neural Tube Defects Tretinoin 10.769142499
MESH:D009447 Neuroblastoma Isotretinoin 3.8417368321
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.6320387270
MESH:D019636 Neurodegenerative Diseases Iron 7.6316604332 17296847
MESH:D020078 Neurogenic Inflammation Quercetin 4.0017929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7120387270
MESH:D009765 Obesity Ascorbic Acid 6.8317217161
MESH:D009765 Obesity Dietary Fats 6.8317217161 21332399 11836018 18674790 16723640 19632207 20132043 20518802 18457598
MESH:D009765 Obesity pirinixic acid 6.8320558911
MESH:D009784 Occupational Diseases Hydrochloric Acid 4.4212378975
MESH:D010003 Osteoarthritis Iron 3.7316640825
MESH:D010024 Osteoporosis Iron 6.7316640825 16648989
MESH:D010024 Osteoporosis Raloxifene 6.7317882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.9919495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.9915579764 17823083 15758505 17893378
MESH:D010051 Ovarian Neoplasms Estradiol 10.1719401270
MESH:D010051 Ovarian Neoplasms Quercetin 10.1719005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 10.1715276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 10.1716936753
MESH:D010146 Pain Tretinoin 2.6016870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.7616540662
MESH:D010190 Pancreatic Neoplasms Quercetin 7.7616965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 7.7615976015
MESH:D010212 Papilloma Iron 4.1012065085
MESH:D020447 Parasomnias Iron 5.6217352947
MESH:D010300 Parkinson Disease Iron 3.1716563566 16640825
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8512520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 12.7214722030
MESH:D010900 Pituitary Diseases Iron 12.7216604332
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.2916977796 15687265
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5110923243
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 4.9815607125 18573544 18497604 15970105
MESH:D011041 Poisoning Iron 3.9316604332
MESH:D017499 Porokeratosis alitretinoin 5.6016144296
MESH:D017119 Porphyria Cutanea Tarda Iron 9.7816640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.7818163543
MESH:D011230 Precancerous Conditions Cyclosporine 13.4112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 13.412563599
MESH:D011230 Precancerous Conditions Quercetin 13.4119056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3221297632
MESH:D011225 Pre-Eclampsia Iron 4.1216640825
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 20.0617184923
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 20.0618769834
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.0611118676 11222880 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 20.0618042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.5418220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5320887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 17199135
MESH:D011471 Prostatic Neoplasms AGN 194204 2.0316000583
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.0317136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 2.0316740699
MESH:D011471 Prostatic Neoplasms Quercetin 2.0317292933 14715546
MESH:D011471 Prostatic Neoplasms Raloxifene 2.0316536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.0316039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0315067354
MESH:D011472 Prostatitis vinclozolin 4.5418629315
MESH:D011507 Proteinuria Tretinoin 3.2416636307
MESH:D011528 Protozoan Infections Iron 5.6216640825
MESH:D011565 Psoriasis Cyclosporine 2.0816882103
MESH:D011596 Psychomotor Disorders Isotretinoin 5.5218769834
MESH:D011625 Pterygium Tretinoin 4.4016723453
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.6120597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.8115090967
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.9314606601
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.8717975199 17365031 17322281 15814490
MESH:D011693 Purpura Raloxifene 5.1515770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.1919058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 8.3718379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 8.3716784557 16129981 17627322 18339021 18549715
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 5.9611510729
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4618990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.7720516732
MESH:D012148 Restless Legs Syndrome Iron 4.2516930377
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.1916849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7416283617 16116481
MESH:D012554 Schistosomiasis japonica Quercetin 5.1416862918
MESH:D012871 Skin Diseases Ascorbic Acid 5.2218709164
MESH:D012871 Skin Diseases halofuginone 5.2211874485
MESH:D012878 Skin Neoplasms Iron 11.9912065085
MESH:D012878 Skin Neoplasms sodium arsenite 11.9919524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.9916192470
MESH:D012878 Skin Neoplasms Tretinoin 11.9916467112
MESH:D013088 Spermatocele Diethylstilbestrol 10.5116002989 16709447
MESH:D013088 Spermatocele Tamoxifen 10.5116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6419457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4912854658
MESH:D013272 Stomach Diseases Dexamethasone 3.9315472012
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.1918456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 3.1917575124 12958204
MESH:D013274 Stomach Neoplasms Tretinoin 3.1917261132
MESH:D013276 Stomach Ulcer Ascorbic Acid 10.3218726076
MESH:D013276 Stomach Ulcer Dexamethasone 10.3215138204
MESH:D013276 Stomach Ulcer Hydrochloric Acid 10.3217189318 16755016 15309881
MESH:D020521 Stroke Ascorbic Acid 7.9616517955 16403987
MESH:D020521 Stroke Raloxifene 7.9616837676
MESH:D013398 Sudden Infant Death Iron 5.0516640825
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.187505956
MESH:D013964 Thyroid Neoplasms Tretinoin 6.1817045167 16026305
MESH:D013978 Tibial Fractures Estradiol 12.3719048282
MESH:D013978 Tibial Fractures Raloxifene 12.3719048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.4516051514
MESH:D014376 Tuberculosis Iron 7.3516597321
MESH:D014376 Tuberculosis Tretinoin 7.3516040207
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 14.0516712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Quercetin 14.0516720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 14.0517572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 14.0516712894 11723127 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.0516712894 17572228 8653321
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 13.9116175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 13.9111813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 13.9116129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.7714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.7015809267 16690809
MESH:D014604 Uveal Neoplasms Tretinoin 4.2116752155
MESH:D014605 Uveitis Cyclosporine 10.431336536
MESH:D014605 Uveitis Dexamethasone 10.431336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.0516002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 4.0317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1912125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.8116837676
MESH:D014820 Vitiligo Tretinoin 3.6816761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.1516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8515886252
MESH:D015430 Weight Gain Dietary Fats 3.4116723640
MESH:D009396 Wilms Tumor Tretinoin 3.6416287080
MESH:D014985 Xerophthalmia Cyclosporine 4.0417120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27770
    • No data
    Releated disease ID Related disease Name
    PA444818Lung Neoplasms
    Releated drug ID Related drug Name
    PA131301952gefitinib
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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