AutismKB 2.0

Annotation Detail for EMP2


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Basic Information Top
Gene Symbol:EMP2 ( MGC9056,XMP )
Gene Full Name: epithelial membrane protein 2
Band: 16p13.13
Quick LinksEntrez ID:2013; OMIM: 602334; Uniprot ID:EMP2_HUMAN; ENSEMBL ID: ENSG00000213853; HGNC ID: 3334
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1726Charcot-Marie-Tooth disease
1942Emphysema
2052Infection
No data
Desease Name
Attention deficit hyperactivity disorder
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of EMP2 mRNAdecreases expression 19933214
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of EMP2 mRNAincreases expression 16631469
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of EMP2 mRNAdecreases expression 20382639
19150397
C006780 bisphenol A bisphenol A results in increased expression of EMP2 mRNAincreases expression 16474171
D016572 Cyclosporine Cyclosporine results in decreased expression of EMP2 mRNAdecreases expression 20106945
D004317 Doxorubicin EMP2 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004958 Estradiol Estradiol results in increased expression of EMP2 mRNAincreases expression 16474171
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of EMP2 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of EMP2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EMP2 mRNAaffects cotreatment|increases expression 17942748
D005047 Etoposide EMP2 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D019833 Genistein Genistein results in increased expression of EMP2 mRNAincreases expression 16474171
D016685 Mitomycin EMP2 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of EMP2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of EMP2 mRNAincreases expression 19482888
C006253 pirinixic acid pirinixic acid results in increased expression of EMP2 mRNAincreases expression 18301758
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of EMP2 mRNAincreases expression 16474171
D012643 Selenium Selenium results in increased expression of EMP2 mRNAincreases expression 19244175
D013629 Tamoxifen Tamoxifen affects the expression of EMP2 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EMP2 mRNAincreases expression 20106945
11489354
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EMP2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of EMP2 mRNAdecreases expression 19933214
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EMP2 mRNAincreases expression 17942748
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of EMP2 mRNAdecreases expression 17951470
D014212 Tretinoin Tretinoin results in increased expression of EMP2 mRNAincreases expression 18230668
D014747 Vinblastine EMP2 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
C025643 vinclozolin vinclozolin affects the expression of EMP2 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4414745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.936195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.9315322242 14514962 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8417505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0118653653
MESH:D000230 Adenocarcinoma Doxorubicin 9.9617418594
MESH:D000230 Adenocarcinoma Estradiol 9.9611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.9614692618
MESH:D000230 Adenocarcinoma Genistein 9.9611473722
MESH:D018248 Adenoma, Liver Cell Phenobarbital 16.6617620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.6616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.6616835633
MESH:D000419 Albuminuria Doxorubicin 4.4421441931
MESH:D000505 Alopecia Tretinoin 3.5315955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8511748828
MESH:D001008 Anxiety Disorders vinclozolin 3.5519015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.9815885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.9816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2416292516
MESH:D001249 Asthma Tretinoin 2.3116456186
MESH:D001471 Barrett Esophagus Tretinoin 4.2916935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.6819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.6812125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.6816206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6915746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 11.8114601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 11.8114601052
MESH:D001862 Bone Resorption bisphenol A 3.7611985600
MESH:D001932 Brain Neoplasms Doxorubicin 3.7117150277
MESH:D001943 Breast Neoplasms bisphenol A 4.6517123778
MESH:D001943 Breast Neoplasms Doxorubicin 4.6515668708 15939500 15993339 16935488 15567936 15634643 16322301 15136595 15692762 16595493 15994142 18695136 16096432 19526202 18234424 18628466 11325840 16264153 16826403 18382427 17426702 17983394 16115903 17369602
MESH:D001943 Breast Neoplasms Estradiol 4.6517289903 17261762 12948864 14630087 18497071 17018787 19861407 16675129
MESH:D001943 Breast Neoplasms Etoposide 4.6516322251
MESH:D001943 Breast Neoplasms Genistein 4.6516541309 16873071 17200150
MESH:D001943 Breast Neoplasms Tamoxifen 4.6518855134 19221464 18984771 19155303 19142967 15668708 18425577 20544844 16202921 20135344 20005174 19189210 19289846 11161223 17242785 18815881 19410462 18351453 20065188 20859285 20390343 18629630 18821012 17893378 18997820 19189212 17440819 19288272 19487384 15565566 19103187 19115204 19244106 19011961 16818667 19084267 17049068 19200415 19066611 19059307 16873071 21152245 17261762 16273361 21138602
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.6520435547
MESH:D001943 Breast Neoplasms Tretinoin 4.6516873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4816813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3516111702
MESH:D002276 Carcinoid Tumor Doxorubicin 4.7016051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4019066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0516168501
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.1717876044 18059187 16023760 16234567
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.1716924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 11.1716924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.1717173139 20007298 1701930 6705139 20935162
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.1716924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.171917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.8817123778
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.7916201981 1485588
MESH:D002292 Carcinoma, Renal Cell Vinblastine 6.791485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.686189445
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.6816051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3118670907 16120746 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.4617308081 16269455 17519947 16731534 16242529 16278810 15476868 18627295 16455267 15792986 17974986 16364871 17928571 17131338 17924179 16952015 17382496 15505089 16612575 16651473 17007740 16109756 15811867 17329180 17351982
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9116243910 17334414
MESH:D002318 Cardiovascular Diseases Genistein 3.2316332659
MESH:D002386 Cataract Tretinoin 3.0317460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.7020889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.7012371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.7018566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.144080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0716835633
MESH:D002779 Cholestasis Cyclosporine 12.8719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.8716105132 11677210 16919318 17333356 17681005 15861022 17110522
MESH:D002779 Cholestasis pirinixic acid 12.8719176532
MESH:D002822 Choriocarcinoma Tretinoin 5.0516461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.6115340226 8697196 12621046 15668235 16354765
MESH:D002972 Cleft Palate Tretinoin 5.619407595
MESH:D003092 Colitis Selenium 9.1317936198
MESH:D003092 Colitis Tretinoin 9.1317035595
MESH:D003110 Colonic Neoplasms Genistein 2.2717182828
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.6418259882 18802399
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 3.6415531428
MESH:D015179 Colorectal Neoplasms Vinblastine 3.6418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9614669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4115322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.4117551590 9125849 10589399 9664655 16925845 8800419 9142499 14991402 9224671 9211117
MESH:D003456 Cryptorchidism vinclozolin 4.2314966744
MESH:D003704 Dementia Polychlorinated Biphenyls 4.6016140633
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2519031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.2416647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2417107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.5219279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.5219279558
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 6.0717416283
MESH:D056486 Drug-Induced Liver Injury Selenium 6.0715131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0720420201
MESH:D004362 Drug Toxicity Doxorubicin 7.8418602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.8411462148
MESH:D004421 Dystonia Phenobarbital 3.901851702
MESH:D004487 Edema pirinixic acid 6.2012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.5916714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 11.5918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.5912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.5919031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.4816402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 22.5817359293
MESH:D016889 Endometrial Neoplasms Estradiol 22.5818566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 22.5811473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 22.5817893378 16202921 19155303 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 22.5816569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9210568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.0518037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.003659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.7711558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.8320417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.456401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.147750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.913659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.0520426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.5611564622
MESH:D005124 Eye Abnormalities Tretinoin 8.5616938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 17.8919224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 17.8915345470
MESH:D005234 Fatty Liver pirinixic acid 17.8920131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 17.8919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3511858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4214745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 11.0819069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 11.0819069698
MESH:D005355 Fibrosis Cyclosporine 14.0912639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.0920067830
MESH:D005355 Fibrosis Tretinoin 14.0917994277
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.1916417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.118708960
MESH:D005909 Glioblastoma Doxorubicin 11.5217150277
MESH:D005909 Glioblastoma Genistein 11.5216598420
MESH:D005909 Glioblastoma Tretinoin 11.5217312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4910696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.6015692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.6016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0516084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.3411294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.349664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 3.4114766674 16144979 16879835 18674790 16244372 16244371 18006777 16330681 16495754 16707910 17875725 12587719 17888722
MESH:D006333 Heart Failure Doxorubicin 11.4117481944
MESH:D006333 Heart Failure pirinixic acid 11.4120558911
MESH:D006333 Heart Failure Selenium 11.4117162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.8015692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2311000095
MESH:D006529 Hepatomegaly Phenobarbital 13.7516109766
MESH:D006529 Hepatomegaly pirinixic acid 13.7518467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.7512621046 16120746 15340226
MESH:D006558 Herpes Genitalis Estradiol 4.9315709030
MESH:D006561 Herpes Simplex Etoposide 4.4510809021
MESH:D006689 Hodgkin Disease Doxorubicin 11.9517606976 15147373 18501091
MESH:D006689 Hodgkin Disease Etoposide 11.9518180244 15147373 16135485 17606976 16200630
MESH:D006689 Hodgkin Disease Vinblastine 11.9518501091 18180244
MESH:D019584 Hot Flashes Estradiol 3.6517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.948697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Tretinoin 3.1216870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4616778211
MESH:D006943 Hyperglycemia pirinixic acid 3.0820558911
MESH:D006973 Hypertension Cyclosporine 4.8110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8118670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7016945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.4217937319
MESH:D007248 Infertility, Male vinclozolin 6.4216467254
MESH:D007249 Inflammation Tamoxifen 4.7019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.7012200463 12878042
MESH:D007251 Influenza, Human Selenium 4.0916624496
MESH:D007333 Insulin Resistance bisphenol A 11.9016393666
MESH:D007333 Insulin Resistance Estradiol 11.9016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 11.9016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.6617994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.5916580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.5917551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3415604871
MESH:D007674 Kidney Diseases Cyclosporine 9.7218776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 9.7216775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 9.7215618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.6416707910
MESH:D007676 Kidney Failure, Chronic Selenium 9.6416518626
MESH:D007680 Kidney Neoplasms Cyclosporine 11.8512371664
MESH:D007680 Kidney Neoplasms Estradiol 11.8515610895
MESH:D007680 Kidney Neoplasms Tamoxifen 11.8518625569
MESH:D007938 Leukemia Genistein 6.2317468513 18980019
MESH:D007938 Leukemia Tretinoin 6.2317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.0516085563
MESH:D007951 Leukemia, Myeloid Tretinoin 3.6016932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0616294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0819225113 12679006 19029980 16823087 17301526 17361223 16766008 19642359 15748426 17712046 16331271 16788101 17368321 16891316 16935935 17649720 17217047 19075265 17339181 17506722 17107899 17294898 16140955 19035177 9834237
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6216417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.239224671
MESH:D008064 Lipidoses Tamoxifen 3.0815342952 17567588
MESH:D008103 Liver Cirrhosis Phenobarbital 2.8321047994
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 10.7316595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.7314659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 10.7317823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.7315474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.7318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.7312878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.7318397230 16248980
MESH:D008107 Liver Diseases Phenobarbital 2.1519363144
MESH:D008113 Liver Neoplasms Mitomycin 13.8115113037
MESH:D008113 Liver Neoplasms Phenobarbital 13.8119812893 19073162 21047994 15975961 19482888 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 13.8120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tamoxifen 13.8116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.8116984957
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 13.6116842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 13.611399818 18308698 17172636 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 13.611423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.6112151625
MESH:D008175 Lung Neoplasms Doxorubicin 3.356189445 17418594
MESH:D008175 Lung Neoplasms Tamoxifen 3.3518625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3511884234 19555203
MESH:D008223 Lymphoma Doxorubicin 7.6516098063
MESH:D008223 Lymphoma Etoposide 7.6512854902 12556972
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7017654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.4615621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6519428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 18.0815458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 18.0811807958 17203775 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 18.0812929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Selenium 18.0815318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 18.0816827153 14580682 19196723 11731420 19196722
MESH:D020149 Manganese Poisoning Estradiol 12.2919453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.2919453300
MESH:D008527 Medulloblastoma Tretinoin 2.7417453147
MESH:D008545 Melanoma Doxorubicin 7.1916827129
MESH:D008545 Melanoma Tamoxifen 7.1912393984 19393235
MESH:D008545 Melanoma Tretinoin 7.1916752155
MESH:D008545 Melanoma Vinblastine 7.1915577320 15577323 18176117 17761969 12374674 16809738 16248763 18505091 18332650 16432458
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0715990972
MESH:D008591 Meningomyelocele Tretinoin 4.3216940565
MESH:D008654 Mesothelioma Doxorubicin 6.1517638057
MESH:D008654 Mesothelioma Selenium 6.1515107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6816801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.4015792986
MESH:D052016 Mucositis Doxorubicin 4.6817415656
MESH:D009135 Muscular Diseases pirinixic acid 3.4016239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0217596541
MESH:D009203 Myocardial Infarction Doxorubicin 9.2219429709 15857846
MESH:D009203 Myocardial Infarction Genistein 9.2217141266
MESH:D009203 Myocardial Infarction pirinixic acid 9.2219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 13.6816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 13.6817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.6816411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3717484760
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.7318259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.7319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4819410462
MESH:D009369 Neoplasms pirinixic acid 4.7317405874
MESH:D009369 Neoplasms Tretinoin 4.7316594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8919196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6217289903
MESH:D009401 Nephrosis Doxorubicin 4.6616899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.9818481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.9816889571 15640375
MESH:D009421 Nervous System Malformations bisphenol A 29.6016427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 29.6016427766 11399458
MESH:D009421 Nervous System Malformations Genistein 29.6016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 29.6014600291
MESH:D009421 Nervous System Malformations Tretinoin 29.609125849
MESH:D009436 Neural Tube Defects Tretinoin 2.989142499
MESH:D009447 Neuroblastoma Doxorubicin 3.2115555623
MESH:D009503 Neutropenia Vinblastine 4.4717378895
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D010018 Osteomalacia Phenobarbital 4.2617016548
MESH:D010024 Osteoporosis Genistein 3.1819401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.9816169203
MESH:D012516 Osteosarcoma Doxorubicin 4.0215930896
MESH:D010049 Ovarian Diseases bisphenol A 4.8811985600
MESH:D010051 Ovarian Neoplasms Estradiol 7.7019401270
MESH:D010051 Ovarian Neoplasms Genistein 7.7019005980
MESH:D010051 Ovarian Neoplasms Tretinoin 7.7016936753
MESH:D010146 Pain Tretinoin 2.8116870215
MESH:D010190 Pancreatic Neoplasms Etoposide 12.1019003803
MESH:D010190 Pancreatic Neoplasms Mitomycin 12.1015113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 12.1016965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 12.1015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5811578682
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.3516702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1412520081
MESH:D003557 Phyllodes Tumor Doxorubicin 5.0517983394
MESH:D010954 Plasmacytoma Selenium 4.7815087411
MESH:D010997 Pleural Neoplasms Doxorubicin 5.0517638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4518163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.6512371664
MESH:D011230 Precancerous Conditions Phenobarbital 8.652563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 15.6310548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.6311222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 15.6319015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.8318220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.2120887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.2120887781
MESH:D011471 Prostatic Neoplasms bisphenol A 2.0916740699
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0916888761 15749863 16868541 16729912 15897917 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 2.0916740699
MESH:D011471 Prostatic Neoplasms Etoposide 2.0917172428
MESH:D011471 Prostatic Neoplasms Genistein 2.0915256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.0915721890
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0915067354
MESH:D011472 Prostatitis vinclozolin 4.8318629315
MESH:D011507 Proteinuria Tretinoin 3.5016636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.2015861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.3912752131
MESH:D011565 Psoriasis Cyclosporine 2.1916882103
MESH:D011625 Pterygium Tretinoin 4.6816723453
MESH:D011629 Puberty, Precocious bisphenol A 4.6810548101
MESH:D051437 Renal Insufficiency Doxorubicin 4.1117922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.3319058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7318990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9916116481 16283617
MESH:D012509 Sarcoma Doxorubicin 3.8917710206 16767912 15625365 18313854 17203757 15675481
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.1914601052 16326096
MESH:D012512 Sarcoma, Ewing's Etoposide 10.1914601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6817846226
MESH:D012640 Seizures Phenobarbital 2.623137016 16876388 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.716407741
MESH:D012878 Skin Neoplasms Doxorubicin 9.1715692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.1716192470
MESH:D012878 Skin Neoplasms Tretinoin 9.1716467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.4617203757 15625365 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 11.2116709447
MESH:D013088 Spermatocele Tamoxifen 11.2116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9319457130
MESH:D013274 Stomach Neoplasms Tretinoin 1.7917261132
MESH:D019966 Substance-Related Disorders bisphenol A 3.8816684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0615669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8012697716
MESH:D013964 Thyroid Neoplasms Doxorubicin 11.5317909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.531399818
MESH:D013964 Thyroid Neoplasms Tretinoin 11.5317045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.5819048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.6916051514
MESH:D014376 Tuberculosis Tretinoin 3.1616040207
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 5.0717653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.0716712894 8653321 17572228
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.5816129372
MESH:D014591 Uterine Diseases bisphenol A 4.9014652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.5016752155
MESH:D014605 Uveitis Cyclosporine 3.881336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.9415577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4414671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.1117334414 17638931 16364871 17678736
MESH:D014820 Vitiligo Tretinoin 3.9516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1415886252
MESH:D009396 Wilms Tumor Tretinoin 3.8716287080
MESH:D014985 Xerophthalmia Cyclosporine 4.3417120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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