AutismKB 2.0

Annotation Detail for EMP3


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Basic Information Top
Gene Symbol:EMP3 ( YMP )
Gene Full Name: epithelial membrane protein 3
Band: 19q13.33
Quick LinksEntrez ID:2014; OMIM: 602335; Uniprot ID:EMP3_HUMAN; ENSEMBL ID: ENSG00000142227; HGNC ID: 3335
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1860Brain tumor
2258Keratoconus
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of EMP3 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of EMP3 proteinaffects expression 20106945
C430898 AGN 194204 AGN 194204 results in decreased expression of EMP3 mRNAdecreases expression 16339527
D000643 Ammonium Chloride Ammonium Chloride affects the expression of EMP3 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of EMP3 mRNAdecreases expression 20458559
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 17639512
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of EMP3 mRNAincreases expression 19737606
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of EMP3 mRNAincreases expression 15003993
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in decreased expression of EMP3 mRNAdecreases expression 16934159
D016572 Cyclosporine Cyclosporine results in increased expression of EMP3 mRNAincreases expression 20106945
D002945 Cisplatin EMP3 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004041 Dietary Fats Dietary Fats results in increased expression of EMP3 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of EMP3 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of EMP3 mRNAdecreases expression 17557909
C065180 fluvastatin [zoledronic acid co-treated with fluvastatin] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 16996129
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 17183730
D017239 Paclitaxel Paclitaxel results in increased expression of EMP3 mRNAincreases expression 19682730
C041786 palm oil palm oil results in increased expression of EMP3 mRNAincreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of EMP3 mRNAaffects binding|decreases expression|increases activity 19710929
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 17639512
C010327 salinomycin salinomycin results in decreased expression of EMP3 mRNAdecreases expression 19682730
D012643 Selenium Selenium results in increased expression of EMP3 mRNAincreases expression 19244175
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EMP3 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EMP3 mRNAincreases expression 17337447
D014212 Tretinoin Tretinoin results in increased expression of EMP3 mRNAincreases expression 16054129
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 17183730
D014810 Vitamin E Vitamin E results in increased expression of EMP3 mRNAincreases expression 19244175
C088658 zoledronic acid [zoledronic acid co-treated with fluvastatin] results in increased expression of EMP3 mRNAaffects cotreatment|increases expression 16996129
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.6114514962 15322242 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.618875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.7419490988
MESH:D000138 Acidosis Ammonium Chloride 3.3518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7317505938
MESH:D058186 Acute Kidney Injury Cisplatin 8.4815814532 12690470 17670903
MESH:D058186 Acute Kidney Injury zoledronic acid 8.4819715164
MESH:D055371 Acute Lung Injury pirinixic acid 2.9218653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 5.2720200999
MESH:D000230 Adenocarcinoma arsenic trioxide 6.8119825857 11798837
MESH:D000230 Adenocarcinoma Cisplatin 6.8117638652 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.8114692618
MESH:D000236 Adenoma beta-Naphthoflavone 3.2119389873
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.2016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.2016835633
MESH:D000505 Alopecia Tretinoin 3.4515955085
MESH:D000550 Amblyopia Valproic Acid 5.0217688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7611748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0517084956
MESH:D000799 Angioedema Acetaminophen 3.6310982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.4117497229
MESH:D001161 Arteriosclerosis Dietary Fats 9.2215238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.2211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.7815885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.7816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2216292516
MESH:D001249 Asthma Tretinoin 2.2816456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.7715336622
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8517157402 17688650 18558336 18396377 18985861 18940202 18775368 19460635 17507914 19232924 16609825 15238991 18316065 18177632 20603192
MESH:D001327 Autoimmune Diseases Quercetin 4.2019761891
MESH:D001471 Barrett Esophagus Tretinoin 4.2016935849
MESH:D001714 Bipolar Disorder Valproic Acid 2.9720046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 20.3916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 20.3919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 20.3912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 20.3916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.5815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.588888407
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.6714601052
MESH:D001859 Bone Neoplasms Paclitaxel 10.1815867366
MESH:D001859 Bone Neoplasms zoledronic acid 10.1815867366 16121404 17312309 11697798 16778634 19442620
MESH:D001862 Bone Resorption zoledronic acid 4.5118404659 18496637 11869084 16769263 15845617 8053405
MESH:D001943 Breast Neoplasms Ascorbic Acid 5.6216443354
MESH:D001943 Breast Neoplasms Cisplatin 5.6218382427 19526202
MESH:D001943 Breast Neoplasms Dietary Fats 5.6220435547
MESH:D001943 Breast Neoplasms Paclitaxel 5.6218323546 11325840 18234424 16115903 16273361 15136595 16244791 18223236
MESH:D001943 Breast Neoplasms Quercetin 5.6218628248
MESH:D001943 Breast Neoplasms salinomycin 5.6219682730
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.6220435547
MESH:D001943 Breast Neoplasms Tretinoin 5.6216873071 16443354 16166294
MESH:D001943 Breast Neoplasms zoledronic acid 5.6218695136 16096432
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.3816813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1311589617
MESH:D002105 Cadmium Poisoning Quercetin 5.3316962696
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.7216050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6316835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9516168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.553084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 13.5512907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 13.5514691202 15073043 16217749 15553829 11135700
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 13.5517982673
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 13.5516313753
MESH:D006528 Carcinoma, Hepatocellular Quercetin 13.5512508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 13.551917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 5.7412023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 5.7419233551
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7517234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6619014326
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 3.7518507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9312490120
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 4.646189445 17066447 18337622
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.6416096774 16051514
MESH:D006332 Cardiomegaly Quercetin 6.4219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.4218670907 16120746 18850075
MESH:D002386 Cataract Acetaminophen 6.8210977129
MESH:D002386 Cataract Tretinoin 6.8217460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.3912371664
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3816129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6320734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D002779 Cholestasis Cyclosporine 12.4519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.4517333356 16919318 17110522 17681005 15861022 11677210 16105132
MESH:D002779 Cholestasis pirinixic acid 12.4519176532
MESH:D002822 Choriocarcinoma Tretinoin 4.9516461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.4712621046 15340226 16354765 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 5.479407595
MESH:D003092 Colitis Selenium 8.8117936198
MESH:D003092 Colitis Tretinoin 8.8117035595
MESH:D003110 Colonic Neoplasms Quercetin 2.3916640504 11134977 19056647 17191121 15741050 17148506 19440933
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.6820501625
MESH:D015179 Colorectal Neoplasms Cisplatin 4.6815273666
MESH:D015179 Colorectal Neoplasms Paclitaxel 4.6818802399
MESH:D015179 Colorectal Neoplasms Quercetin 4.6818852136 18095365
MESH:D003139 Common Cold Ascorbic Acid 5.2617323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8814669216 17141729
MESH:D003327 Coronary Disease fluvastatin 4.6816142594
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 7.0610525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.0610048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 7.0616925845 9224671 9664655 9142499 14991402 9211117 10589399 8800419 17551590 9125849
MESH:D019465 Craniofacial Abnormalities Valproic Acid 7.0616575769 8888407 17688650
MESH:D019465 Craniofacial Abnormalities Vitamin E 7.0619769572
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9015213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3318249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.5619496084
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 4.3816506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.3817107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.3412392966 11529661 18713872 14725611 12153990 10663392 2444490 11421492 19923254 16109766 15619225 11461765 10774834 17906064 14550746 17522070 19420014 19739265 12540782 16781746 11743745 18071297 11739529 10915739 16081117 19416960 12594235 12958197 17562736 11834606 19164858 14986274 16177239 16227642 16393943 12705907 19085960 11287661 19370779 16485898 15968718
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 11.3417851650
MESH:D056486 Drug-Induced Liver Injury Selenium 11.3415131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.3420420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 11.341733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8919426721
MESH:D004362 Drug Toxicity Cisplatin 7.6719839026 12649298 12231392 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.6711462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3018367378
MESH:D004421 Dystonia Valproic Acid 3.851851702
MESH:C538011 Eales disease Ascorbic Acid 12.369068938
MESH:C538011 Eales disease Vitamin E 12.369068938
MESH:D004487 Edema pirinixic acid 5.9212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.9212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.2316714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 11.2318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.9912538720
MESH:D016889 Endometrial Neoplasms Tretinoin 2.9716569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8410568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.9517275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.7116628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8320417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.416426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.097750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.853659116
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.1012903497
MESH:D004938 Esophageal Neoplasms Cisplatin 7.1015464296 16481741 15173087 17638652 16785472
MESH:D004938 Esophageal Neoplasms Paclitaxel 7.1016481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.3211564622
MESH:D005124 Eye Abnormalities Tretinoin 8.329664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 28.2515073043
MESH:D005234 Fatty Liver Cyclosporine 28.2519224547
MESH:D005234 Fatty Liver Dietary Fats 28.2517967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver Ethinyl Estradiol 28.2515345470
MESH:D005234 Fatty Liver pirinixic acid 28.2520131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 28.2514986274 19224547
MESH:D005264 Femoral Fractures zoledronic acid 5.6216234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2511858732
MESH:D005315 Fetal Diseases Valproic Acid 4.6716575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.9318558336 8888407
MESH:D005355 Fibrosis Cyclosporine 25.5212639820 12168785
MESH:D005355 Fibrosis Dietary Fats 25.5218296743
MESH:D005355 Fibrosis Quercetin 25.5219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 25.5220067830
MESH:D005355 Fibrosis Tretinoin 25.5217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0616904648
MESH:D005756 Gastritis Acetaminophen 3.4616983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.018708960
MESH:D005909 Glioblastoma Quercetin 6.8119804834
MESH:D005909 Glioblastoma Tretinoin 6.8117312396
MESH:D005910 Glioma Quercetin 2.9717643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3810696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 7.4515102660 15464296
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.4516096774
MESH:D034381 Hearing Loss Cisplatin 4.1219898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9516084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.2515464296
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 15.1216080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 15.1210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 15.1214991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 15.1216080930
MESH:D006333 Heart Failure pirinixic acid 6.5320558911
MESH:D006333 Heart Failure Selenium 6.5317162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1511000095
MESH:D006529 Hepatomegaly pirinixic acid 7.5719772884 19176532 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.5715340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 5.8816490937 16863852
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.8816490937 16863852
MESH:D006689 Hodgkin Disease Cisplatin 3.4216200630 16170182
MESH:D019584 Hot Flashes Vitamin E 3.7614716179
MESH:D006849 Hydrocephalus Valproic Acid 4.6617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8315340226 16354765 18606429 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 12.1916870215
MESH:D006930 Hyperalgesia Tretinoin 12.1916870215
MESH:D006930 Hyperalgesia zoledronic acid 12.1916769263
MESH:D006934 Hypercalcemia zoledronic acid 4.8619622757 18089816
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4021332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.3616778211
MESH:D006943 Hyperglycemia pirinixic acid 8.6320558911
MESH:D006943 Hyperglycemia Quercetin 8.6311834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.4221332399
MESH:D006973 Hypertension Cyclosporine 8.1110903974
MESH:D006973 Hypertension Quercetin 8.1118356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.1118850075 18670907
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.4216612254
MESH:D006996 Hypocalcemia zoledronic acid 5.9812669777
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6016569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3517937319
MESH:D007249 Inflammation Dietary Fats 4.5620412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.5612200463 12878042
MESH:D007251 Influenza, Human Quercetin 17.3916624496
MESH:D007251 Influenza, Human Selenium 17.3916624496
MESH:D007251 Influenza, Human Vitamin E 17.3916624496
MESH:D007333 Insulin Resistance Dietary Fats 6.8018457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 6.8016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.5617994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.3016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.3015992940 17551590
MESH:D007627 Keloid Quercetin 4.7517086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2315604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.9315464296
MESH:D007674 Kidney Diseases Acetaminophen 17.7915629191 12587719
MESH:D007674 Kidney Diseases Cisplatin 17.7912649298 19839026 18289764 12231392 15190930
MESH:D007674 Kidney Diseases Cyclosporine 17.798314463 10903974 18776723
MESH:D007674 Kidney Diseases Quercetin 17.7916962696
MESH:D007674 Kidney Diseases Vitamin E 17.7912488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.7016518626
MESH:D007680 Kidney Neoplasms Cyclosporine 2.5712371664
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.5811231351
MESH:D007938 Leukemia arsenic trioxide 9.9115070760
MESH:D007938 Leukemia Quercetin 9.9117468513
MESH:D007938 Leukemia Tretinoin 9.9117143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 9.3417077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 9.3418089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.8419077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.8416482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.8816467208 19850784 20471514 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.8817596541 19850784 16294345
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 5.8816294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.1817869043 19035177 15622746 11161223 12018890 11468182 12679006 17649720 19225113 15213294 16966277 17107899 16330433 9834237 17712046 16112521 15748426 16823087 15336539 16891316 17217047 19075265 16331271 12712474 19642359
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.1819035177 17712046 16331271 9834237 19642359 19075265 16766008 16891316 15748426 17339181 17217047 17294898 12679006 17107899 17368321 17361223 16140955 16788101 17506722 16823087 19225113 17649720 17301526 19029980 16935935
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1516882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.169224671
MESH:D008080 Liposarcoma Paclitaxel 4.6317353645
MESH:D008103 Liver Cirrhosis Dietary Fats 2.7618296743
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.4415474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.4412741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.4412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.4418397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.4416169303
MESH:D008107 Liver Diseases Acetaminophen 1.5816610002 19784758 12587719 12969438 11587558 19460945 16611625 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0516871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 16.9415890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 16.9414682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 16.9419389873 21295105
MESH:D008113 Liver Neoplasms pirinixic acid 16.9420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 16.9418980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.9416984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 21.708603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 21.7020377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 21.7018544905
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 21.7018164116
MESH:D008114 Liver Neoplasms, Experimental Quercetin 21.7019519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.7012151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1915213294
MESH:D008171 Lung Diseases Ascorbic Acid 7.2616863852
MESH:D008171 Lung Diseases Vitamin E 7.2616863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.0517228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 10.2914755239
MESH:D008175 Lung Neoplasms arsenic trioxide 10.2919825857 11798837
MESH:D008175 Lung Neoplasms Ascorbic Acid 10.2916401635
MESH:D008175 Lung Neoplasms Cisplatin 10.2911798837 6189445 17225452
MESH:D008175 Lung Neoplasms Quercetin 10.2916280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.2911884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 10.2911062179
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.9214749477
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 9.5019682730
MESH:D008325 Mammary Neoplasms, Experimental Selenium 9.5015318939
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 9.5017312309
MESH:D008527 Medulloblastoma Tretinoin 2.7017453147
MESH:D008545 Melanoma Cisplatin 5.0211135225 16809738 12883367 17761969 12393984 16248763 18176117 18505091 18332650 15577323 12374674 16432458 17023156
MESH:D008545 Melanoma Paclitaxel 5.0212040289 16342250 12025231
MESH:D008545 Melanoma Tretinoin 5.0216752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.5615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3619513568
MESH:D008591 Meningomyelocele Tretinoin 4.2216940565
MESH:D008654 Mesothelioma Cisplatin 9.8717638057
MESH:D008654 Mesothelioma Selenium 9.8715107826
MESH:D008654 Mesothelioma zoledronic acid 9.8716675582
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5816801185
MESH:D008881 Migraine Disorders Valproic Acid 3.0418803445 18765137
MESH:D009101 Multiple Myeloma arsenic trioxide 16.1811468182 14977855 19549372 19417148 15949261
MESH:D009101 Multiple Myeloma fluvastatin 16.1816996129
MESH:D009101 Multiple Myeloma Paclitaxel 16.1814749477
MESH:D009101 Multiple Myeloma zoledronic acid 16.1818089719 19621390 16996129
MESH:D009135 Muscular Diseases pirinixic acid 3.3016239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.848888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 11.6216882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 11.6217596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 11.6217596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.4419151258
MESH:D009203 Myocardial Infarction Quercetin 5.4419595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8512213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.9116411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.9119207477
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7616624393
MESH:D009362 Neoplasm Metastasis Paclitaxel 6.1115867366
MESH:D009362 Neoplasm Metastasis zoledronic acid 6.1117312309 15867366 19139120
MESH:D009369 Neoplasms Cisplatin 11.0416773208
MESH:D009369 Neoplasms pirinixic acid 11.0417405874
MESH:D009369 Neoplasms Quercetin 11.0415185748
MESH:D009369 Neoplasms Tretinoin 11.0416594593 16946489
MESH:D009395 Nephritis, Interstitial Cisplatin 4.2815464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1118481113 19348381
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.8414600291
MESH:D009421 Nervous System Malformations Tretinoin 8.849125849
MESH:D009436 Neural Tube Defects arsenic trioxide 11.3710525206
MESH:D009436 Neural Tube Defects Tretinoin 11.379142499
MESH:D009436 Neural Tube Defects Valproic Acid 11.378888407 16359493
MESH:D009447 Neuroblastoma Cisplatin 3.348761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7018514411
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.498761367
MESH:D020078 Neurogenic Inflammation Quercetin 4.1717929310
MESH:D009765 Obesity Ascorbic Acid 7.1717217161
MESH:D009765 Obesity Dietary Fats 7.1718674790 20132043 19632207 20518802 21332399 16723640 17217161 11836018 18457598
MESH:D009765 Obesity pirinixic acid 7.1720558911
MESH:D010014 Osteolysis Paclitaxel 11.5815867366
MESH:D010014 Osteolysis zoledronic acid 11.5815867366
MESH:D010024 Osteoporosis zoledronic acid 3.9117882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0219495926
MESH:D010051 Ovarian Neoplasms arsenic trioxide 14.2916624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Cisplatin 14.2919769630 6897625 17225452 15464296
MESH:D010051 Ovarian Neoplasms Paclitaxel 14.2911161223
MESH:D010051 Ovarian Neoplasms Quercetin 14.2919005980
MESH:D010051 Ovarian Neoplasms Tretinoin 14.2916936753
MESH:D010146 Pain Acetaminophen 10.3616870215
MESH:D010146 Pain Tretinoin 10.3616870215
MESH:D010146 Pain zoledronic acid 10.3616475674
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.7515580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 11.7519003803
MESH:D010190 Pancreatic Neoplasms Quercetin 11.7516965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.7515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4911578682
MESH:D010235 Paraganglioma arsenic trioxide 3.9719927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0412520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.1115464296
MESH:D010954 Plasmacytoma Selenium 4.6815087411
MESH:D010997 Pleural Neoplasms Cisplatin 5.1317638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3618163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.5112371664
MESH:D011230 Precancerous Conditions Quercetin 8.5119056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.7611896295 11222880 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 8.7620603192
MESH:D011471 Prostatic Neoplasms marker/mechanism 15583422
MESH:D011471 Prostatic Neoplasms AGN 194204 1.9016000583
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.9019131511
MESH:D011471 Prostatic Neoplasms Paclitaxel 1.9016356831 17136230 17172428 16729912
MESH:D011471 Prostatic Neoplasms Quercetin 1.9017292933 14715546
MESH:D011471 Prostatic Neoplasms Vitamin E 1.9015084515
MESH:D011471 Prostatic Neoplasms zoledronic acid 1.9019103299 12438248
MESH:D011507 Proteinuria Tretinoin 3.4116636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1015861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.3312752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D011625 Pterygium Tretinoin 4.5816723453
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.1214606601
MESH:D051437 Renal Insufficiency Cisplatin 4.2015464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6418990726
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2516849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.2116283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 10.2119155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 16.2116646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 16.2114601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 16.2116121404
MESH:D012554 Schistosomiasis japonica Quercetin 5.3316862918
MESH:D012559 Schizophrenia Valproic Acid 2.0419110320 15737665
MESH:D012640 Seizures Valproic Acid 2.601511512 17978042 16876388 11044598 14763951 3137016 15475178 11738929
MESH:D012871 Skin Diseases Ascorbic Acid 5.0218709164
MESH:D012871 Skin Diseases Vitamin E 5.0218709164
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 8.868532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.8616192470
MESH:D012878 Skin Neoplasms Tretinoin 8.8616467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.1315464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7316709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6219490988
MESH:D013226 Status Epilepticus Valproic Acid 4.3312833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.6017007042
MESH:D013274 Stomach Neoplasms Cisplatin 4.6018396642 17522103 15958060
MESH:D013274 Stomach Neoplasms Paclitaxel 4.6018506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 4.6017261132
MESH:D013276 Stomach Ulcer Ascorbic Acid 3.7118726076
MESH:D020521 Stroke Ascorbic Acid 8.3416403987 16517955
MESH:D020521 Stroke Vitamin E 8.3416517955
MESH:D024801 Tauopathies Paclitaxel 4.6016930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.4315464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6912697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.6819014326
MESH:D013964 Thyroid Neoplasms Tretinoin 6.6817045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.6016051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7515213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.0217262798
MESH:D014376 Tuberculosis Tretinoin 3.1016040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.313119515
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 7.9811780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 7.9815464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Quercetin 7.9816720314
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.448888407
MESH:D014581 Urticaria Acetaminophen 2.7810982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.9616803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.9616129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1014692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4016752155
MESH:D014605 Uveitis Cyclosporine 3.771336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.4015577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3514671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.8516761959
MESH:D014839 Vomiting Cisplatin 4.5111897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0415886252
MESH:D015430 Weight Gain Dietary Fats 3.5616723640
MESH:D009396 Wilms Tumor Tretinoin 3.7916287080
MESH:D014985 Xerophthalmia Cyclosporine 4.2317120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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