AutismKB 2.0

Annotation Detail for ENG


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ENG ( CD105,END,FLJ41744,HHT1,ORW,ORW1 )
Gene Full Name: endoglin
Band: 9q34.11
Quick LinksEntrez ID:2022; OMIM: 131195; Uniprot ID:EGLN_HUMAN; ENSEMBL ID: ENSG00000106991; HGNC ID: 3349
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200126ALK1 signaling events
200172HIF-1-alpha transcription factor network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1731Growth retardation
1742Moyamoya disease
1746Hypertension, Pulmonary
1801Intracranial aneurysm
1818Systemic scleroderma
1845Psoriasis
1901Endometriosis
1904Diabetes mellitus
1918Atherosclerosis
1932Pancreatitis
1934Cancer
2044Pre-Eclampsia
2100Hepatitis C
2134Amyotrophic lateral sclerosis
2157Scleroderma
2162Capillaries disease
Desease Name
Intracranial Aneurysm
CARDIOVASCULAR
arteriovenous dysplasias brain hemorrhage
pulmonary arterial hypertension sclerosis, systemic
Desease Name
Metabolic syndrome
Desease Name
Hereditary hemorrhagic telangiectasia-1
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of ENG mRNAincreases expression 16788091
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of ENG mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of ENG mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ENG mRNAdecreases expression 20458559
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of ENG mRNAincreases expression 15336504
C081643 candesartan candesartan inhibits the reaction [AGT protein results in increased expression of ENG mRNA]decreases reaction|increases expression 15539634
C081643 candesartan candesartan inhibits the reaction [AGT protein results in increased expression of ENG protein]decreases reaction|increases expression 15539634
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of ENG mRNAdecreases expression 17484886
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ENG mRNAaffects cotreatment|affects expression 17602206
C014347 decitabine decitabine inhibits the reaction [tobacco tar results in decreased expression of ENG mRNA]decreases expression|decreases reaction 19559774
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ENG mRNAaffects cotreatment|affects expression 17602206
D004958 Estradiol Estradiol affects the expression of ENG mRNAaffects expression 15598610
D019808 Losartan Losartan inhibits the reaction [AGT protein results in increased expression of ENG mRNA]decreases reaction|increases expression 15539634
D019808 Losartan Losartan inhibits the reaction [AGT protein results in increased expression of ENG protein]decreases reaction|increases expression 15539634
C093973 PD 98059 PD 98059 inhibits the reaction [AGT protein results in increased expression of ENG protein]decreases reaction|increases expression 15539634
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ENG mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of ENG mRNAdecreases expression 19482888
D020849 Raloxifene Raloxifene results in increased expression of ENG mRNAincreases expression 20135064
D020849 Raloxifene Raloxifene results in increased expression of ENG proteinincreases expression 20135064
C009166 retinol acetate retinol acetate results in increased expression of ENG mRNAincreases expression 16772331
D012643 Selenium Selenium results in increased expression of ENG mRNAincreases expression 19244175
D017632 Asbestos, Serpentine Asbestos, Serpentine results in decreased expression of ENG mRNAdecreases expression 16251409
C004648 testosterone enanthate testosterone enanthate affects the expression of ENG mRNAaffects expression 17440010
C024746 tobacco tar decitabine inhibits the reaction [tobacco tar results in decreased expression of ENG mRNA]decreases expression|decreases reaction 19559774
C024746 tobacco tar tobacco tar results in decreased expression of ENG mRNAdecreases expression 19559774
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of ENG mRNA]decreases reaction|increases expression 15539634
C081489 valsartan valsartan inhibits the reaction [AGT protein results in increased expression of ENG protein]decreases reaction|increases expression 15539634
C025643 vinclozolin vinclozolin affects the expression of ENG mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 8.267525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.266195326
MESH:D000230 Adenocarcinoma arsenic trioxide 4.2819825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 4.2811473722
MESH:D000236 Adenoma Diethylnitrosamine 2.786695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.8419061943 19052882 16434500 17162532 17620307 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.8417620307
MESH:D000419 Albuminuria Losartan 11.5112586211
MESH:D000419 Albuminuria Raloxifene 11.5117308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5115800139
MESH:D000799 Angioedema Acetaminophen 3.7110982225
MESH:D001008 Anxiety Disorders vinclozolin 3.5319015723
MESH:D001195 Asbestosis Asbestos, Serpentine 5.5410751356
MESH:D050197 Atherosclerosis Losartan 4.4210821809
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.5516206674
MESH:D001930 Brain Injuries Raloxifene 4.3416580743
MESH:D001943 Breast Neoplasms decitabine 1.9719208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9717474063
MESH:D001943 Breast Neoplasms Estradiol 1.9712948864 18497071 17289903 17018787 19861407 16675129 17261762 14630087
MESH:D001943 Breast Neoplasms Raloxifene 1.9715572757 17440819 15758505 15775269 16912660 17952589 16837676 17893378 17595753 17049068 17242785 17261762
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2011589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.653786805 18705752 16124888 16097048 16192424 16227642 10355542 15673190 16011737 15721981 16050911 15700767
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.113084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.1115553829 14691202 11135700 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.1118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.1119519916 16878318 3581430 16288022 18785209 17173139 20084675 16502159 19394651 19208518 3084413 10672840 19052882 16328049 18393292 20514400 19335982 17055752 16807293 17138121 18210153 19171122 19701751 18506893 10737359 17978847 20935162 19539802 20432363 17761372 20512989 18788625 21159647 19919837 18978308 16698587 16935385 11831363 19418558 19107877 17428255 20214788 18971187 20524982 16569478 16830150 20101231 18056438 16779866 18494052 16540662 16681979 19383236 19822196 20727157 18691550 20007298 18665156 17162532
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.1116924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.1117173139 6705139 20007298 20935162 1701930
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7519014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0012490120
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.5619215824
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.9617572228
MESH:D006332 Cardiomegaly Losartan 7.6912586211 15969258
MESH:D006332 Cardiomegaly valsartan 7.6919597038
MESH:D009202 Cardiomyopathies valsartan 4.3516247790
MESH:D002318 Cardiovascular Diseases Raloxifene 7.5715775269
MESH:D002318 Cardiovascular Diseases valsartan 7.5711230374
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.1714694615
MESH:D002386 Cataract Acetaminophen 7.1710977129
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.8217174075 7505956 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.8218566989
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 10.8219559774
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.124080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.5719052882
MESH:D003072 Cognition Disorders Raloxifene 4.4915800139
MESH:D003092 Colitis Selenium 3.6517936198
MESH:D003110 Colonic Neoplasms decitabine 2.3117616700
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5520501625
MESH:D015179 Colorectal Neoplasms decitabine 2.5518981723
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.0515095906
MESH:D003324 Coronary Artery Disease valsartan 3.8517719468
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0612609071
MESH:D003384 Coxsackievirus Infections valsartan 5.7120392896
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8810525206
MESH:D003456 Cryptorchidism vinclozolin 4.2114966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9715213294
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0517474826
MESH:D003921 Diabetes Mellitus, Experimental valsartan 4.4911508273
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.1620387270
MESH:D003928 Diabetic Nephropathies Estradiol 14.5519279558
MESH:D003928 Diabetic Nephropathies Raloxifene 14.5517308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies valsartan 14.5518630688 11427623
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 11.6121346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.6116109766 19416960 16081117 14550746 17562736 15968718 19370779 10915739 19923254 11421492 16485898 19085960 2444490 14725611 16393943 12153990 19420014 12540782 18713872 16227642 11739529 11287661 11743745 12958197 10663392 18071297 10774834 14986274 12594235 12705907 19164858 17522070 11529661 17906064 15619225 11461765 12392966 16177239 11834606 16781746 19739265
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 11.613732212 21278145 11566570 9327722 6623471 7440962 19336974 19085960 10092053 15998439 15027814 7120509 6884620 10915739 7179309 15968718 2869522 16227642 3786805 16177239 17522070 4309450
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.6119107877
MESH:D056486 Drug-Induced Liver Injury Selenium 11.6115131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9719426721
MESH:D004421 Dystonia Phenobarbital 3.881851702
MESH:D004487 Edema Raloxifene 3.2215860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 3.8715845917
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9919294695
MESH:D016889 Endometrial Neoplasms Estradiol 2.9019148513 18566989 11473722
MESH:D004751 Enteritis candesartan 6.2217763956
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.983659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.743922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8220417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.436401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.127750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.893659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.2812903497
MESH:D005234 Fatty Liver arsenic trioxide 17.8215073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 17.8216045604 19224547 12795759 61145 15959796 16239168 17595544 12631006
MESH:D005234 Fatty Liver Diethylnitrosamine 17.8221071580 20387270
MESH:D005234 Fatty Liver Raloxifene 17.8217473493
MESH:D005355 Fibrosis Carbon Tetrachloride 8.8318705752
MESH:D005355 Fibrosis valsartan 8.8316893502
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1316904648
MESH:D005756 Gastritis Acetaminophen 3.5516983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.1716417039
MESH:D015432 Glomerulonephritis, Membranoproliferative valsartan 5.4116928621
MESH:D005923 Glomerulosclerosis, Focal Segmental candesartan 5.7816687628
MESH:D006258 Head and Neck Neoplasms decitabine 3.4019215824
MESH:D006331 Heart Diseases Raloxifene 3.4411110106
MESH:D006333 Heart Failure Losartan 11.7510979640
MESH:D006333 Heart Failure Selenium 11.7517162251
MESH:D006333 Heart Failure valsartan 11.7519027736
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4719900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 3.3616109766
MESH:D006558 Herpes Genitalis Estradiol 4.9015709030
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.6217440010
MESH:D019584 Hot Flashes Estradiol 3.6217088409
MESH:D006930 Hyperalgesia Acetaminophen 2.6016870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4016899240
MESH:D006973 Hypertension Losartan 8.8115969258 14597852 12586211 12512695 10090350
MESH:D006973 Hypertension Raloxifene 8.8117577099 15787275
MESH:D006973 Hypertension valsartan 8.8111427623 12692753 10903974 16475468 12850387 18390891 18344623 20102058
MESH:D006974 Hypertension, Malignant valsartan 6.2811560862
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9615338365
MESH:D007248 Infertility, Male decitabine 6.6317581917
MESH:D007248 Infertility, Male vinclozolin 6.6316467254
MESH:D007249 Inflammation Diethylnitrosamine 5.4818785209
MESH:D007249 Inflammation Losartan 5.4812586211
MESH:D007251 Influenza, Human Selenium 4.0716624496
MESH:D007333 Insulin Resistance Estradiol 2.8816393666 16627594
MESH:D007674 Kidney Diseases Acetaminophen 9.7612587719 15629191
MESH:D007674 Kidney Diseases Estradiol 9.7615618244
MESH:D007674 Kidney Diseases valsartan 9.7616893502 12164870 10903974
MESH:D007676 Kidney Failure, Chronic Selenium 3.7616518626
MESH:D007680 Kidney Neoplasms Estradiol 2.8715610895
MESH:D007889 Leiomyoma Raloxifene 4.3716973256
MESH:D007938 Leukemia arsenic trioxide 6.2415070760
MESH:D007938 Leukemia decitabine 6.2419235587 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6717077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 11.2816972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 11.2816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.1819077051
MESH:D007951 Leukemia, Myeloid decitabine 9.1817236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9120471514 16467208 16968895 19850784 17050201
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.9118704418 18206229 17679729 19010910 19387464 18460780
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.3318055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1319225113 17869043 19642359 15622746 19075265 11161223 16891316 16330433 16823087 12679006 17107899 17217047 16966277 12018890 11468182 15748426 17649720 9834237 15213294 17712046 19035177 15336539 16112521 16331271 12712474
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2216882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6016417039
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.6111408273 16239168 16943688 21278145 16221502 11903743 17157831 17174718 17334410
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.6118665156 18407596 20032147 19638242 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 10.6121047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.9818166357 12632512 17944888 20821823 16015684 15650968 12666154 18376398 18317297 16033810 14724832 18279442 18705752 17640975 15057751 18339082 18481824 12445421 16116963 10355542 17565644 18205269 17823541 18395095 14716496 17976157 18395914 17525996 14512876 17766677 18472094 12609069 18006644 17721639 15730626 17714472 14620537 15876570 15370692 18251166 12546737 18187930 12649538 15996030 17481882 12958196 15673190 17631135 15925388 16097048 17557913 13678700 17869086 14716833 18472332 12667390 17761835 15893842 12632514 15052691 12898905 11481614 14748882 12586293 17922224 12741479 16136751 15362042 17698563 16027843 16638106 18263696 17805973 16192424 15338365 18420326 18412020 18156304 18054572 18418968 15818738 18429990 12389079 15123356 15931870 17900296 17708605 15959796 16248980 16011737 18210741 18277467 12445418
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.9814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Losartan 4.9812445418 15573910 17900296
MESH:D008106 Liver Cirrhosis, Experimental valsartan 4.9815619341 15504291 16872305
MESH:D008107 Liver Diseases Acetaminophen 9.0916611625 16610002 12969438 11587558 19784758 12587719 19014921 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.0916964402 15830285 17285989 15720792 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 9.0917034775
MESH:D008107 Liver Diseases Phenobarbital 9.0919363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0315123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.0216871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.0216899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 13.7314682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 13.7319294768
MESH:D008113 Liver Neoplasms Clofibric Acid 13.7317602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.7315175105 20118626 19690152 21071580 19254457 19996281 19812893 19073162 12112319 19256749 20452335 19427195 21278145 20434301 20101389 19255062 19499222 19642983 18648771 20583210 19638242 16942905 12771043 20501860 20137499 19850985 20405173 19294768 10737359 2862719 20492335 2422723 19426721 9163691 18644402 21167192 21047994 19551842 18754104 18977376 15885732 18978307 19090486 19833225
MESH:D008113 Liver Neoplasms Phenobarbital 13.7319812893 15975961 19482888 19073162 21047994 8742319
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.4720377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.4712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.4718164116 19539802 21159647 18775883 19004024 18544905 16842330 18079962 18282651 19009564 9362446 16267830 2563599 18093689 19126423 17942915 18253720 3124819 17854601 18308698 17174075 19519916
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 13.476150874 1399818 18308698 17172636 2563599
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2515213294
MESH:D008171 Lung Diseases Asbestos, Serpentine 4.2617200189
MESH:D008175 Lung Neoplasms arsenic trioxide 3.5519825857 11798837
MESH:D008175 Lung Neoplasms Asbestos, Serpentine 3.5511198217
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.5521163286 6695378 20970405 20512841
MESH:D008223 Lymphoma decitabine 3.3319470736
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.7411807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.7415318939
MESH:D020149 Manganese Poisoning Estradiol 4.3519453300
MESH:D008382 Marfan Syndrome Losartan 5.9419430350
MESH:D008545 Melanoma decitabine 2.2317785578 16505122
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4419513568
MESH:D008654 Mesothelioma Selenium 2.7415107826
MESH:D008881 Migraine Disorders candesartan 5.1818759728
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4315863610
MESH:D009101 Multiple Myeloma arsenic trioxide 11.6314977855 19417148 15949261 19549372 11468182
MESH:D009101 Multiple Myeloma decitabine 11.6318172295
MESH:D009101 Multiple Myeloma Raloxifene 11.6316497877
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.2516105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 7.2519157545 16882708 18608210 19010910
MESH:D009203 Myocardial Infarction Losartan 4.1912692751
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.1816810080
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3417484760
MESH:D009232 Myxoma Raloxifene 5.4316343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8316624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.523581430 9029167
MESH:D009369 Neoplasms decitabine 2.6517925555 19116145 19470736
MESH:D009374 Neoplasms, Experimental Asbestos, Serpentine 4.7211704859
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6017289903
MESH:D009421 Nervous System Malformations Estradiol 3.5211399458 16427766
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0310525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.8218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.8220387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 3.9814694615
MESH:D010018 Osteomalacia Phenobarbital 4.2317016548
MESH:D010024 Osteoporosis Raloxifene 3.3117882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.1017823083 15758505 15579764 17893378
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.6716624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms decitabine 7.6719331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 7.6719401270
MESH:D010146 Pain Acetaminophen 2.2916870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.9615580305
MESH:D010190 Pancreatic Neoplasms decitabine 11.9619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.9616540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 11.9616965848
MESH:D010235 Paraganglioma arsenic trioxide 4.0419927285
MESH:D010954 Plasmacytoma Selenium 4.7615087411
MESH:D010995 Pleural Diseases Asbestos, Serpentine 5.5610923243
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.722563599
MESH:D011230 Precancerous Conditions Phenobarbital 8.722563599
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 3.7719015723 18042343 18220299
MESH:D055728 Primary Myelofibrosis decitabine 4.6017616702
MESH:D011469 Prostatic Diseases vinclozolin 4.8018220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6419131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.6416740699
MESH:D011471 Prostatic Neoplasms Raloxifene 2.6416536755 16220300 15731164
MESH:D011472 Prostatitis vinclozolin 4.8018629315
MESH:D011507 Proteinuria candesartan 9.9716687628
MESH:D011507 Proteinuria valsartan 9.9717664856 12164870 18344623
MESH:D019310 Pseudolymphoma Phenobarbital 4.3712752131
MESH:D011658 Pulmonary Fibrosis Asbestos, Serpentine 6.3718569384 15511213
MESH:D011658 Pulmonary Fibrosis valsartan 6.3717241526
MESH:D011693 Purpura Raloxifene 5.4315770314
MESH:D051437 Renal Insufficiency Losartan 5.3915728788
MESH:D012208 Rhabdomyosarcoma decitabine 4.2819155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8316646077
MESH:D012640 Seizures Phenobarbital 2.614039156 3137016 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.696407741
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.638532709
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.3417007042
MESH:D013274 Stomach Neoplasms decitabine 3.3419037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3418456281
MESH:D020521 Stroke Raloxifene 3.7216837676
MESH:D013683 Telangiectasia, Hereditary Hemorrhagic marker/mechanism 20135064
MESH:D013964 Thyroid Neoplasms arsenic trioxide 16.2919014326
MESH:D013964 Thyroid Neoplasms decitabine 16.2917967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 16.297505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 16.291399818
MESH:D013978 Tibial Fractures Estradiol 13.2819048282
MESH:D013978 Tibial Fractures Raloxifene 13.2819048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8315213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.1411780464 20435036 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms decitabine 8.1419087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 8.1417572228
MESH:D014581 Urticaria Acetaminophen 2.8510982225
MESH:D014604 Uveal Neoplasms decitabine 4.7817785578
MESH:D054556 Venous Thromboembolism Raloxifene 5.0816837676
MESH:D020257 Ventricular Remodeling valsartan 5.5719027736
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4316343187
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27785
    • Releated gene ID Related gene Name
    PA27785ENG
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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