AutismKB 2.0

Annotation Detail for EPAS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EPAS1 ( ECYT4,HIF2A,HLF,MOP2,PASD2,bHLHe73 )
Gene Full Name: endothelial PAS domain protein 1
Band: 2p21
Quick LinksEntrez ID:2034; OMIM: 603349; Uniprot ID:EPAS1_HUMAN; ENSEMBL ID: ENSG00000116016; HGNC ID: 3374
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05211Renal cell carcinoma
hsa05200Pathways in cancer
No data
Pathway IDPathway Name
200030HIF-2-alpha transcription factor network
200161Signaling events mediated by VEGFR1 and VEGFR2
No data
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Circulatory system diseases
Hematologic diseases
H00236Congenital polycythemia
Desease IDDesease Name
1781Rheumatoid arthritis
1934Cancer
2025Polyarthritis
Desease Name
NORMALVARIATION
elite endurance
No data
Desease Name
Erythrocytosis, familial, 4
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of EPAS1 mRNAdecreases expression 19933214
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of EPAS1 mRNAdecreases expression 20406850
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of EPAS1 mRNAincreases expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of EPAS1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of EPAS1 mRNAaffects expression 16483693
D000968 Antimycin A Antimycin A inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of EPAS1 mRNAincreases expression 18687144
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of EPAS1 mRNAdecreases expression 19150397
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of EPAS1 mRNAincreases expression 20382639
D016572 Cyclosporine Cyclosporine results in decreased expression of EPAS1 mRNAdecreases expression 20106945
D003676 Deferoxamine Deferoxamine results in increased expression of EPAS1 proteinincreases expression 18353899
C107676 deguelin deguelin results in decreased expression of EPAS1 proteindecreases expression 19336726
C017185 delphinidin delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein]decreases reaction|increases expression 18603805
D004008 Diclofenac Diclofenac results in decreased expression of EPAS1 proteindecreases expression 12912967
D004041 Dietary Fats Dietary Fats results in decreased expression of EPAS1 mRNAdecreases expression 18042831
D019297 2,4-Dinitrophenol 2,4-Dinitrophenol results in increased expression of EPAS1 mRNAincreases expression 15740689
D019297 2,4-Dinitrophenol 2,4-Dinitrophenol results in increased expression of EPAS1 proteinincreases expression 15740689
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of EPAS1 mRNAincreases expression 17351261
C010953 exochelins exochelins results in increased expression of EPAS1increases expression 12460908
C020748 ferrous sulfate ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
C020748 ferrous sulfate ferrous sulfate inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
D005472 Fluorouracil Fluorouracil results in increased expression of EPAS1 mRNAincreases expression 16557594
C037032 galangin ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
C037032 galangin galangin results in increased expression of EPAS1 proteinincreases expression 17973296
C037032 galangin Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNAaffects cotreatment|increases expression 17183730
D006861 Hydrogen Peroxide delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein]decreases reaction|increases expression 18603805
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of EPAS1 proteinincreases expression 18603805
D007052 Ibuprofen Ibuprofen results in decreased expression of EPAS1 proteindecreases expression 12912967
D007501 Iron Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
D007501 Iron Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
D020910 Ketorolac Ketorolac results in decreased expression of EPAS1 proteindecreases expression 12912967
D009151 Mustard Gas Mustard Gas results in increased expression of EPAS1 mRNAincreases expression 15674843
C030517 myxothiazol myxothiazol inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
D010100 Oxygen Antimycin A inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
D010100 Oxygen COX10 protein affects the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]affects reaction|increases expression 18353899
D010100 Oxygen myxothiazol inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
D010100 Oxygen Oxygen deficiency results in increased expression of EPAS1 proteinincreases expression 18353899
D010100 Oxygen Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
D010100 Oxygen Sodium Cyanide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
D010100 Oxygen UQCRFS1 protein affects the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]affects reaction|increases expression 18353899
C041786 palm oil palm oil results in decreased expression of EPAS1 mRNAdecreases expression 18042831
D010656 Phenylephrine Phenylephrine results in decreased expression of EPAS1 mRNAdecreases expression 18158353
D010795 Phthalic Acids Phthalic Acids results in decreased expression of EPAS1 mRNAdecreases expression 15728792
C006253 pirinixic acid pirinixic acid results in increased expression of EPAS1 mRNAincreases expression 17426115
18301758
D011794 Quercetin ferrous sulfate inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
D011794 Quercetin Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]decreases reaction|increases expression 17973296
D011794 Quercetin Quercetin results in increased expression of EPAS1 proteinincreases expression 17973296
D012402 Rotenone Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
C017947 sodium arsenite sodium arsenite affects the expression of EPAS1 mRNAaffects expression 19590694
D012966 Sodium Cyanide Sodium Cyanide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]decreases reaction|increases expression 18353899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNAaffects expression 16962184
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of EPAS1 mRNAdecreases expression 19933214
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased expression of EPAS1 mRNAincreases expression 18087596
D014212 Tretinoin Tretinoin results in increased expression of EPAS1 mRNAincreases expression 17138961
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNAaffects cotreatment|increases expression 17183730
C025643 vinclozolin vinclozolin affects the expression of EPAS1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 11.787525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.7814514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 11.788875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.5419490988
MESH:D000138 Acidosis Ammonium Chloride 3.1318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5017505938
MESH:D058186 Acute Kidney Injury Diclofenac 8.187897758
MESH:D058186 Acute Kidney Injury Ibuprofen 8.186375363
MESH:D055371 Acute Lung Injury Oxygen 7.9116759491
MESH:D055371 Acute Lung Injury pirinixic acid 7.9118653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.4714692618
MESH:D000230 Adenocarcinoma Fluorouracil 6.4717638652
MESH:D000230 Adenocarcinoma Ibuprofen 6.4710697514
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.0915814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.503712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.4716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.4716835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2615276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.4616712894 17306315
MESH:D000505 Alopecia Tretinoin 3.2715955085
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.2216640825
MESH:D000544 Alzheimer Disease Ibuprofen 4.4318351690
MESH:D000544 Alzheimer Disease Iron 4.4316640825 16563566
MESH:D000550 Amblyopia Valproic Acid 4.7917688650
MESH:D000707 Anaphylaxis Ibuprofen 4.829532969
MESH:D000740 Anemia Fluorouracil 12.7416511603 17963324 15504547
MESH:D000740 Anemia Iron 12.7416434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 12.7411748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.8517084956
MESH:D018798 Anemia, Iron-Deficiency Iron 4.2717147795 17162259 17375513 16569441 17163184
MESH:D000756 Anemia, Sideroblastic Iron 4.4316910769
MESH:D000860 Anoxia Oxygen 4.6220872349
MESH:D001008 Anxiety Disorders Valproic Acid 7.7217497229
MESH:D001008 Anxiety Disorders vinclozolin 7.7219015723
MESH:D001145 Arrhythmias, Cardiac Iron 8.1116604332
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 8.1117460149
MESH:D001161 Arteriosclerosis Dietary Fats 8.5115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.3015885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.3016412693
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 4.5019898480
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.5016292516
MESH:D001249 Asthma Mustard Gas 4.4810378619
MESH:D001249 Asthma Tretinoin 4.4816456186
MESH:D001260 Ataxia Telangiectasia Iron 11.6715336622
MESH:D001260 Ataxia Telangiectasia Quercetin 11.6715336622
MESH:D050197 Atherosclerosis Iron 6.3816640825 16632123
MESH:D050197 Atherosclerosis Oxygen 6.3816391483
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.0720106747
MESH:D001321 Autistic Disorder Iron 2.3617352947
MESH:D001321 Autistic Disorder Valproic Acid 2.3617507914 17157402 18985861 18775368 18316065 16609825 15238991 18940202 20603192 17688650 18396377 18177632 19232924 18558336 19460635
MESH:D001327 Autoimmune Diseases Quercetin 3.9919761891
MESH:D001424 Bacterial Infections Iron 4.7616640825
MESH:D001471 Barrett Esophagus Tretinoin 3.9916935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.5811289319 1440618
MESH:D001714 Bipolar Disorder Valproic Acid 2.8517594078 20046352
MESH:D001768 Blister Mustard Gas 4.7319167455
MESH:D001778 Blood Coagulation Disorders ferrous sulfate 18.876421970
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.8719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.8712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.8716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.0815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.088888407
MESH:D001919 Bradycardia Phenylephrine 4.1115306635
MESH:D002545 Brain Ischemia Ibuprofen 4.4515837124
MESH:D001943 Breast Neoplasms Deferoxamine 4.3115993339
MESH:D001943 Breast Neoplasms deguelin 4.3118593368 17035597
MESH:D001943 Breast Neoplasms Dietary Fats 4.3120435547
MESH:D001943 Breast Neoplasms Fluorouracil 4.3116557594 19217205 16595493 15136595 18608205 18357371 16110121
MESH:D001943 Breast Neoplasms Oxygen 4.3117263869
MESH:D001943 Breast Neoplasms Quercetin 4.3118628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.3120435547
MESH:D001943 Breast Neoplasms Tretinoin 4.3116443354 16166294 16873071
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.7315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.5417687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1616813970
MESH:D002100 Cachexia Ibuprofen 5.0415141370
MESH:D002105 Cadmium Poisoning Quercetin 5.1116962696
MESH:D002276 Carcinoid Tumor Fluorouracil 4.2316051944
MESH:D002277 Carcinoma Fluorouracil 7.0617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.0616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7216168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 12.7916705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 12.797296757 3581430
MESH:D006528 Carcinoma, Hepatocellular deguelin 12.7918575727
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 12.7918930000 17971768 17088986 16332177 16799960 17045692
MESH:D006528 Carcinoma, Hepatocellular Quercetin 12.7912508355 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 12.7917306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 12.791917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.2711212258
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5317234771
MESH:D002292 Carcinoma, Renal Cell marker/mechanism 21131975
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.787296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.7818695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 9.6616280240 17066447 18986760 16757204
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 9.6618572023
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 9.6611212258
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 9.6616096774 16051514
MESH:D006332 Cardiomegaly Phenylephrine 10.0315728586 11754973 17124262 11179087 17287366 16170337
MESH:D006332 Cardiomegaly Quercetin 10.0319794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 10.0318670907 18850075 16120746
MESH:D009202 Cardiomyopathies Iron 3.7616640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.3016604332
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.2216936243
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 6.7414694615
MESH:D002386 Cataract Tretinoin 6.7417460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 17.906135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 17.907505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 17.9020889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 17.9012371664
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.9020056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1616129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5420734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8016835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 16.589022650 19486331
MESH:D002779 Cholestasis Cyclosporine 16.5819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 16.5816919318 17110522 16105132 11677210 15861022 17333356 17681005
MESH:D002779 Cholestasis pirinixic acid 16.5819176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7216461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.1215668235 15340226 16354765 8697196 12621046
MESH:D002972 Cleft Palate Tretinoin 5.129407595
MESH:D003092 Colitis Tretinoin 3.2917035595
MESH:D003110 Colonic Neoplasms Fluorouracil 5.4117172411 17725105 17016597 16510598 17287894 15001691 18772588 16340194 17018589 17169374
MESH:D003110 Colonic Neoplasms Iron 5.4116640825
MESH:D003110 Colonic Neoplasms Quercetin 5.4119440933 15741050 17148506 17191121 11134977 16640504 19056647
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.5516524972 18448328 17454858 17016601 16303861 18288408 18509181 15289873 17695437 17255274 20501625 14970324 17401013 16391804 16331619 17594712 16282729 15148649 18383874 18949393 18802399 17094418
MESH:D015179 Colorectal Neoplasms Quercetin 2.5518095365 18852136
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 7.9815095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.9817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.4420055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.449142499 9664655 9211117 14991402 9224671 9125849 8800419 10589399 17551590 16925845
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.4417688650 8888407 16575769
MESH:D003456 Cryptorchidism vinclozolin 3.9314966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.6018551238
MESH:D007644 Darier Disease Fluorouracil 4.3616733453
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4118759878 11906362 8156756 2524372 12868966 14531868 11298694 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2218249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.103621924 2952479
MESH:D003920 Diabetes Mellitus Iron 4.0916604332 16640825
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.3819496084
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.2216506275
MESH:D003924 Diabetes Mellitus, Type 2 Iron 4.1416506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1417107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 10.4621346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 10.4618692083 11289319 18289764 6679447 7440962 9328219 18648102 6482804 1440618 9022650 9653073 16192314 8291058
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 10.4621346803
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.4620420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 10.461733752 19641884
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4411462148
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 5.1818446180 18450898 16133044
MESH:D050171 Dyslipidemias Dietary Fats 3.1418367378
MESH:D004417 Dyspnea Oxygen 4.4020016425
MESH:D004421 Dystonia Valproic Acid 3.651851702
MESH:D004487 Edema Diclofenac 13.3716273134
MESH:D004487 Edema Mustard Gas 13.3711428647 11402378 9260866 11428631
MESH:D004487 Edema pirinixic acid 13.3712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.3711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.4818230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.4818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.7812538720
MESH:D016889 Endometrial Neoplasms Tretinoin 2.8216569247
MESH:D004715 Endometriosis Ibuprofen 8.0015652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.0010568697 9294722
MESH:D019446 Endotoxemia Ibuprofen 4.5411545620
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.7317275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.483922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.7120417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.236426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.887750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.633659116
MESH:D004890 Erythema Mustard Gas 4.739357497
OMIM:611783 ERYTHROCYTOSIS, FAMILIAL, 4 marker/mechanism
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.493581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.4920426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.4916785472 16337965 16481741 17638652 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.7611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.769664655 16938888
MESH:D005128 Eye Diseases Ketorolac 6.6411084241
MESH:D005234 Fatty Liver Cyclosporine 25.7319224547
MESH:D005234 Fatty Liver Dietary Fats 25.7317967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.7315345470
MESH:D005234 Fatty Liver Iron 25.7316640825
MESH:D005234 Fatty Liver pirinixic acid 25.7320131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 25.7319224547 14986274
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0411858732
MESH:D005315 Fetal Diseases Valproic Acid 4.4516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.728888407 18558336
MESH:D005334 Fever Ibuprofen 4.2116997862
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.586705139
MESH:D005355 Fibrosis Cyclosporine 23.2712639820 12168785
MESH:D005355 Fibrosis Dietary Fats 23.2718296743
MESH:D005355 Fibrosis Quercetin 23.2719474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.2720067830
MESH:D005355 Fibrosis Tretinoin 23.2717994277
MESH:D005621 Friedreich Ataxia Iron 5.0116640825 16604332
MESH:D005739 Gas Poisoning Oxygen 4.7820016425
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5016973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.8616417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.2516452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.798708960
MESH:D005909 Glioblastoma Quercetin 6.3119804834
MESH:D005909 Glioblastoma Tretinoin 6.3117312396
MESH:D005910 Glioma Fluorouracil 5.5716145905
MESH:D005910 Glioma Quercetin 5.5717643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.647505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1510696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 6.8115162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.8116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7216084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.7411294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 5.7414991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.2720558911
MESH:D006432 Hemochromatosis Iron 4.1816640825 17053826 16574947 16604332 17255318 17236123
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9511000095
MESH:D006486 Hemosiderosis Iron 4.7816604332
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.116705139
MESH:D006521 Hepatitis, Chronic Diclofenac 5.2414986274
MESH:D006525 Hepatitis, Viral, Human Iron 5.0316640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.5217182432
MESH:D006529 Hepatomegaly Iron 12.0616890145
MESH:D006529 Hepatomegaly pirinixic acid 12.0618467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.0615340226 12621046 16120746
MESH:D015658 HIV Infections Iron 3.4416597321
MESH:D006689 Hodgkin Disease sodium arsenite 2.8012676792
MESH:D006849 Hydrocephalus Valproic Acid 4.4317688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.618697196 16354765 15340226 18606429 16959395
MESH:D006930 Hyperalgesia Tretinoin 2.8816870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2121332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1516778211
MESH:D006943 Hyperglycemia pirinixic acid 8.0020558911
MESH:D006943 Hyperglycemia Quercetin 8.0011834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.2221332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5215034207
MESH:D006973 Hypertension Cyclosporine 10.9010903974
MESH:D006973 Hypertension Phenylephrine 10.9012717712 8949925
MESH:D006973 Hypertension Quercetin 10.9018356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.9018850075 18670907
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.2016612254
MESH:D006984 Hypertrophy Ibuprofen 9.6416672835
MESH:D006984 Hypertrophy Phenylephrine 9.6412791704 18502941
MESH:D007006 Hypogonadism Iron 4.1016640825
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3916945680 16569931
MESH:D007037 Hypothyroidism Iron 4.6616640825
MESH:D007235 Infant, Premature, Diseases Ibuprofen 5.4016133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.5117937319
MESH:D007248 Infertility, Male sodium arsenite 9.5112646999 15346721
MESH:D007248 Infertility, Male vinclozolin 9.5116467254
MESH:D007249 Inflammation Diclofenac 16.9216273134
MESH:D007249 Inflammation Dietary Fats 16.9220412841
MESH:D007249 Inflammation Ibuprofen 16.923291741
MESH:D007249 Inflammation Mustard Gas 16.928975870 16001271 9260866 11428631 17524151 11428620 11428647 11402378 9357497
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.9212200463 12878042
MESH:D007249 Inflammation Tobacco Smoke Pollution 16.9218590791
MESH:D007251 Influenza, Human Quercetin 4.0716624496
MESH:D007333 Insulin Resistance Dietary Fats 6.2918457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 6.2916306350
MESH:D007410 Intestinal Diseases Tretinoin 3.3517994277
MESH:D019189 Iron Metabolism Disorders Iron 4.6417163184
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.589022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.6516580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.6517551590 15992940
MESH:D007627 Keloid Quercetin 4.5317086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0015604871
MESH:D007674 Kidney Diseases Cyclosporine 8.638314463 18776723 10903974
MESH:D007674 Kidney Diseases Quercetin 8.6316962696
MESH:D007674 Kidney Diseases sodium arsenite 8.6320008137
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.8916518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 14.8916705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 14.896582329
MESH:D007680 Kidney Neoplasms Cyclosporine 14.8912371664
MESH:D007680 Kidney Neoplasms Fluorouracil 14.8916985049
MESH:D007938 Leukemia Quercetin 5.7117468513
MESH:D007938 Leukemia Tretinoin 5.7117143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3216482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 5.7420368581
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.7419850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 5.7417596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.8716331271 16788101 16935935 17649720 16766008 17107899 16140955 17339181 15748426 19075265 17217047 9834237 17301526 19642359 12679006 16891316 19225113 19035177 19029980 17712046 17361223 17368321 17294898 16823087 17506722
MESH:D020961 Lewy Body Disease Iron 5.0116563566
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3016417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.009224671
MESH:D008103 Liver Cirrhosis Dietary Fats 6.1418296743
MESH:D008103 Liver Cirrhosis Iron 6.1416640825
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.929327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.4315474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.4312741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.4312878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.4318397230 16248980
MESH:D008107 Liver Diseases Diclofenac 3.5214566034 16867024
MESH:D008108 Liver Diseases, Alcoholic Iron 4.5816737972 17207112
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 19.147678174
MESH:D008113 Liver Neoplasms Fluorouracil 19.1415113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms Iron 19.1416640825 20302851
MESH:D008113 Liver Neoplasms pirinixic acid 19.1420007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 19.1418980244
MESH:D008113 Liver Neoplasms sodium arsenite 19.1415276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 19.1416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 11.852876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 11.85598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Quercetin 11.8519519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 11.8512151625
MESH:D008171 Lung Diseases Mustard Gas 6.5718702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 6.5719095001
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.8217228818
MESH:D055370 Lung Injury Asbestos, Crocidolite 8.1017365036
MESH:D055370 Lung Injury Oxygen 8.1018339021
MESH:D008175 Lung Neoplasms deguelin 11.8419336726 16288123
MESH:D008175 Lung Neoplasms Fluorouracil 11.8415246190
MESH:D008175 Lung Neoplasms Iron 11.8416640825
MESH:D008175 Lung Neoplasms Mustard Gas 11.843148597 8781369
MESH:D008175 Lung Neoplasms Quercetin 11.8416280456
MESH:D008175 Lung Neoplasms sodium arsenite 11.8417077188 16712894 19931552 17306315 15276417
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 11.8411884234 19555203
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 11.8411091918 3440675 16288123 12111688
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3615086387
MESH:D008268 Macular Degeneration Iron 3.7416640825
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 3.4410697514
MESH:D008527 Medulloblastoma Tretinoin 2.6017453147
MESH:D008545 Melanoma sodium arsenite 3.0616487513 19082730
MESH:D008545 Melanoma Tretinoin 3.0616752155
MESH:D008591 Meningomyelocele Tretinoin 4.0016940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.0018303189 16966607 16166281
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3516801185
MESH:D008881 Migraine Disorders Valproic Acid 2.8818765137 18803445
MESH:D009062 Mouth Neoplasms Fluorouracil 7.8618986760 16757204
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 7.8615006635
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.2317086897
MESH:D009135 Muscular Diseases pirinixic acid 3.0916239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.648888407
MESH:D009181 Mycoses Iron 5.0316640825
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.5417596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 6.5417596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.0819151258
MESH:D009203 Myocardial Infarction Quercetin 5.0819595682
MESH:D017202 Myocardial Ischemia Iron 8.0416604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.0412213967
MESH:D015428 Myocardial Reperfusion Injury Iron 12.4116604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.4116411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.4119207477
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.4318551238 7678174
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.293581430
MESH:D009369 Neoplasms deguelin 16.8717764071
MESH:D009369 Neoplasms Fluorouracil 16.8716928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 16.8717405874
MESH:D009369 Neoplasms Quercetin 16.8715185748
MESH:D009369 Neoplasms sodium arsenite 16.8711559025
MESH:D009369 Neoplasms Tretinoin 16.8716594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.2520056578
MESH:D009395 Nephritis, Interstitial Ibuprofen 4.556375363
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.2819348381 18481113
MESH:D009404 Nephrotic Syndrome Iron 8.2817178036
MESH:D009410 Nerve Degeneration Ibuprofen 7.7910961664
MESH:D009410 Nerve Degeneration Rotenone 7.7915790535 18619942 17356569
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.1514600291
MESH:D009421 Nervous System Malformations Tretinoin 8.159125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 14.976679447
MESH:D009436 Neural Tube Defects sodium arsenite 14.9712854658
MESH:D009436 Neural Tube Defects Tretinoin 14.979142499
MESH:D009436 Neural Tube Defects Valproic Acid 14.9716359493 8888407
MESH:D019636 Neurodegenerative Diseases Iron 3.8917296847 16604332
MESH:D020078 Neurogenic Inflammation Quercetin 3.9617929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1416436463
MESH:D009503 Neutropenia Mustard Gas 3.587688884 16761898
MESH:D009765 Obesity Dietary Fats 4.0217217161 11836018 21332399 16723640 19632207 18457598 20518802 20132043 18674790
MESH:D009765 Obesity pirinixic acid 4.0220558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 13.0016049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 13.004026338 6482804
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 13.0014694615
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.583988306
MESH:D010003 Osteoarthritis Diclofenac 11.3618287210
MESH:D010003 Osteoarthritis Ibuprofen 11.367009135
MESH:D010003 Osteoarthritis Iron 11.3616640825
MESH:D010024 Osteoporosis Iron 3.5916640825 16648989
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.8219495926
MESH:D010051 Ovarian Neoplasms Quercetin 7.0519005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.0515276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 7.0516936753
MESH:D010146 Pain Diclofenac 9.6013679232
MESH:D010146 Pain Ibuprofen 9.603291741
MESH:D010146 Pain Tretinoin 9.6016870215
MESH:D010149 Pain, Postoperative Ibuprofen 4.7116678543
MESH:D010190 Pancreatic Neoplasms Fluorouracil 10.9916929163 16500647 19003803 15113037
MESH:D010190 Pancreatic Neoplasms Ibuprofen 10.9912384795
MESH:D010190 Pancreatic Neoplasms Quercetin 10.9916965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 10.9915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 13.227296757
MESH:D010212 Papilloma Hydrogen Peroxide 13.2212065085
MESH:D010212 Papilloma Iron 13.2212065085
MESH:D020447 Parasomnias Iron 5.5817352947
MESH:D010300 Parkinson Disease Iron 5.1816640825 16563566
MESH:D010300 Parkinson Disease Rotenone 5.1818191903 11535288 18619942 11445065 16412576 19114014 19232380 15451049 16140633
MESH:D020734 Parkinsonian Disorders Rotenone 3.7015927086 15795934 18197244 15574749
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8112520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.036228378
MESH:D010900 Pituitary Diseases Iron 5.2316604332
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.4710923243
MESH:D011041 Poisoning Iron 7.6916604332
MESH:D011041 Poisoning Mustard Gas 7.6915727166
MESH:D017119 Porphyria Cutanea Tarda Iron 9.6616640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.6618163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.9012371664
MESH:D011230 Precancerous Conditions Quercetin 7.9019056647
MESH:D011225 Pre-Eclampsia Iron 4.0916640825
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 13.7411118676 11896295 11399792 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 13.7420603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 13.7418220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.5018220299
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.2519082440 18626508
MESH:D011471 Prostatic Neoplasms Ibuprofen 2.2517409433
MESH:D011471 Prostatic Neoplasms Quercetin 2.2514715546 17292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.2516039940
MESH:D011472 Prostatitis vinclozolin 4.5018629315
MESH:D011507 Proteinuria Ibuprofen 8.196375363
MESH:D011507 Proteinuria Tretinoin 8.1916636307
MESH:D011528 Protozoan Infections Iron 5.5816640825
MESH:D011537 Pruritus Ethinyl Estradiol 8.1015861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.1018058305
MESH:D019310 Pseudolymphoma Valproic Acid 4.1011422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.0716882103
MESH:D011625 Pterygium Tretinoin 4.3616723453
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 5.3117975199 15814490 17365031 17322281
MESH:D011658 Pulmonary Fibrosis Mustard Gas 5.3117894541 17266442 17720292 10334151 17620002
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6515538739 18286688 16160472 18722050
MESH:D015427 Reperfusion Injury pirinixic acid 2.1719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 4.1217627322 18339021
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.2118410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4318990726
MESH:D012148 Restless Legs Syndrome Iron 4.2216930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.053692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 9.5416283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 9.5419155313
MESH:D012554 Schistosomiasis japonica Quercetin 5.1116862918
MESH:D012559 Schizophrenia Valproic Acid 2.0119110320 15737665
MESH:D012640 Seizures 2,6-dinitrotoluene 4.9718551238
MESH:D012640 Seizures Valproic Acid 4.9715475178 17978042 14763951 16876388 3137016 11738929 11044598 1511512
MESH:D012852 Sinusitis Phenylephrine 4.277327846
MESH:D012871 Skin Diseases Mustard Gas 2.5912880345 16961503 15451306
MESH:D012878 Skin Neoplasms deguelin 23.9016041863
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 23.9012065085
MESH:D012878 Skin Neoplasms Iron 23.9012065085
MESH:D012878 Skin Neoplasms sodium arsenite 23.9018572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 23.9016192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 23.9018590791
MESH:D012878 Skin Neoplasms Tretinoin 23.9016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.5016709447
MESH:D016135 Spinal Dysraphism sodium arsenite 8.4412854658
MESH:D016135 Spinal Dysraphism Valproic Acid 8.4419490988
MESH:D013226 Status Epilepticus Valproic Acid 4.1012833885
MESH:D013274 Stomach Neoplasms Fluorouracil 2.3917522103 19015929 18396642 18567086 19084572 16424979 17172411 15786421 16951190 17498489
MESH:D013274 Stomach Neoplasms Tretinoin 2.3917261132
MESH:D013398 Sudden Infant Death Iron 11.8816640825
MESH:D013398 Sudden Infant Death Oxygen 11.8812563064
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.053712494 6582329 7505956 1399818 6587162
MESH:D013964 Thyroid Neoplasms Tretinoin 6.0517045167 16026305
MESH:D014062 Tongue Neoplasms Fluorouracil 8.5916280240
MESH:D014062 Tongue Neoplasms Tretinoin 8.5916051514
MESH:D014178 Translocation, Genetic Valproic Acid 4.7917262798
MESH:D014376 Tuberculosis Iron 7.2616597321
MESH:D014376 Tuberculosis Tretinoin 7.2616040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.093119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 13.8516049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 13.858074119
MESH:D001749 Urinary Bladder Neoplasms Quercetin 13.8516720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 13.8516452187 17306315 11723127 16712894
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 13.8512846360
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.228888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.8910091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 13.7016803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 13.7011813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 13.7016129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.1716752155
MESH:D014605 Uveitis Cyclosporine 3.541336536
MESH:D014652 Vascular Diseases sodium arsenite 3.9917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1512125929
MESH:D020301 Vasospasm, Intracranial Ibuprofen 4.7619057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1514671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.6516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8115886252
MESH:D015430 Weight Gain Dietary Fats 3.3816723640
MESH:D009396 Wilms Tumor Tretinoin 3.6016287080
MESH:D014985 Xerophthalmia Cyclosporine 4.0017120751
Pathway ID Pathway Name
KEGG:05200 Pathways in cancer
KEGG:05211 Renal cell carcinoma
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27809
    • No data
    No data
    Releated drug ID Related drug Name
    PA448478l-arginine
    PA450635nitric oxide
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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