AutismKB 2.0

Annotation Detail for EPHX1


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Basic Information Top
Gene Symbol:EPHX1 ( EPHX,EPOX,MEH )
Gene Full Name: epoxide hydrolase 1, microsomal (xenobiotic)
Band: 1q42.12
Quick LinksEntrez ID:2052; OMIM: 132810; Uniprot ID:HYEP_HUMAN; ENSEMBL ID: ENSG00000143819; HGNC ID: 3401
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00980Metabolism of xenobiotics by cytochrome P450
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1709Parkinson disease
1712Yersinia infection
1804Chronic obstructive airway disease
1848Embryoma
1859Ovarian cancer
1903Larynx cancer
1918Atherosclerosis
1942Emphysema
1944Breast cancer
1976Squamous cell cancer
2008Liver disease
2022Liver cancer
2044Pre-Eclampsia
2053Colon cancer
2066Lung cancer
2079Optic atrophy
2154Adenoma
Desease Name
PAH-DNA adducts
DNA Damage
emphysema
preeclampsia.
polycystic ovary syndrome
colorectal cancer
CARDIOVASCULAR
COPD severity
Birth Weight
prostate cancer
CANCER
infant birthweight
COPD
esophageal cancer
IMMUNE
asbestosis or pleural plaques
METABOLIC
chronic obstructive pulmonary disease/COPD
lung cancer
preeclampsia
polycystic ovary syndrome.
REPRODUCTION
colorectal polyps (adenoma or hyperplastic)
head and neck cancer
No data
Desease Name
Preeclampsia, susceptibility to
Hypercholanemia, familial
Fetal hydantoin syndrome
Diphenylhydantoin toxicity
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C004822 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamideaffects chemical synthesis|affects metabolic processing 15692831
C004822 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide [EPHX1 protein results in increased metabolism of carbamazepine epoxide] which results in increased chemical synthesis of 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamideincreases chemical synthesis|increases metabolic processing 15692831
C026486 1,2,5,6-dibenzanthracene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1,2,5,6-dibenzanthracene]increases metabolic processing|increases reaction 8961944
C026486 1,2,5,6-dibenzanthracene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene]increases metabolic processing|increases reaction 8961944
C026486 1,2,5,6-dibenzanthracene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1,2,5,6-dibenzanthracene]increases metabolic processing|increases reaction 8961944
C026486 1,2,5,6-dibenzanthracene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene]increases metabolic processing|increases reaction 8961944
C012277 1,2-diamino-4-nitrobenzene 1,2-diamino-4-nitrobenzene results in increased expression of EPHX1 mRNAincreases expression 17070881
C031763 1,3-butadiene EPHX1 5' UTR polymorphism results in increased susceptibility to 1,3-butadieneincreases response to substance 15716486
C031763 1,3-butadiene EPHX1 gene polymorphism results in increased susceptibility to 1,3-butadieneincreases response to substance 12605384
11238181
C031763 1,3-butadiene GSTM1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1,3-butadiene]increases reaction|increases response to substance 11238181
C031763 1,3-butadiene GSTT1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1,3-butadiene]increases reaction|increases response to substance 11238181
C031763 1,3-butadiene EPHX1 gene mutant form results in increased susceptibility to 1,3-butadieneincreases response to substance 16730686
12929123
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea results in increased expression of EPHX1 mRNAincreases expression 10190572
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea results in increased expression of EPHX1 proteinincreases expression 10190572
C035314 1-nitropropane 1-nitropropane results in decreased expression of EPHX1 mRNAdecreases expression 17070881
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of EPHX1 mRNAdecreases expression 17547211
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of EPHX1 mRNAincreases expression 17070881
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of EPHX1 mRNAaffects expression 21346803
C025235 2,6-diaminotoluene 2,6-diaminotoluene results in decreased expression of EPHX1 mRNAdecreases expression 17070881
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of EPHX1 mRNAaffects expression 21346803
C014706 2-nitro-4-phenylenediamine 2-nitro-4-phenylenediamine results in increased expression of EPHX1 mRNAincreases expression 17070881
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of EPHX1 mRNAincreases expression 14600272
15890375
C016617 2-nitropropane 2-nitropropane results in increased expression of EPHX1 mRNAincreases expression 17070881
C028676 4-acetylaminofluorene 4-acetylaminofluorene results in increased expression of EPHX1 mRNAincreases expression 17070881
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of EPHX1 mRNAaffects expression 21346803
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EPHX1 mRNAincreases expression 14600272
15890375
D000082 Acetaminophen Acetaminophen affects the expression of EPHX1 mRNAaffects expression 17562736
15606129
D000082 Acetaminophen [Acetaminophen results in increased activity of and results in increased localization of NFE2L2 protein] which results in increased expression of EPHX1 mRNAincreases activity|increases expression|increases localization 15122755
D016604 Aflatoxin B1 EPHX1 gene SNP affects the susceptibility to Aflatoxin B1affects response to substance 12907637
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of EPHX1 mRNAincreases expression 15890375
14600272
D000348 Aflatoxins EPHX1 gene polymorphism results in increased susceptibility to Aflatoxinsincreases response to substance 15734960
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in increased expression of EPHX1 mRNAincreases expression 16940010
D000643 Ammonium Chloride Ammonium Chloride affects the expression of EPHX1 mRNAaffects expression 16483693
C526219 apple polyphenol extract apple polyphenol extract results in decreased expression of EPHX1 mRNAdecreases expression 16369997
C006632 arsenic trioxide arsenic trioxide results in decreased expression of EPHX1 mRNAdecreases expression 17547211
C015001 arsenite arsenite results in increased expression of EPHX1 mRNAincreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in increased expression of EPHX1 mRNA]affects reaction|increases expression 18929588
D001194 Asbestos EPHX1 gene polymorphism affects the susceptibility to Asbestosaffects response to substance 17159790
D001194 Asbestos EPHX1 protein affects the susceptibility to Asbestosaffects response to substance 15993904
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNAaffects cotreatment|decreases expression 17639512
C030935 benz(a)anthracene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benz(a)anthracene]increases metabolic processing|increases reaction 8961944
C030935 benz(a)anthracene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benz(a)anthracene]increases metabolic processing|increases reaction 8961944
C030935 benz(a)anthracene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benz(a)anthracene]increases metabolic processing|increases reaction 8961944
C030935 benz(a)anthracene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benz(a)anthracene]increases metabolic processing|increases reaction 8961944
D001554 Benzene EPHX1 protein results in increased metabolism of Benzeneincreases metabolic processing 17885617
D001554 Benzene EPHX1 protein affects the reaction [Benzene results in increased expression of CDKN1A mRNA]affects reaction|increases expression 12655032
D001554 Benzene EPHX1 protein affects the susceptibility to Benzeneaffects response to substance 12655032
D001554 Benzene Benzene affects the expression of EPHX1 mRNAaffects expression 15878777
C015700 benzo-1,2,3-thiadiazole benzo-1,2,3-thiadiazole results in increased expression of EPHX1 mRNAincreases expression 8951341
C023393 benzo(a)pyrene 7,8-oxide CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7,8-oxide]affects hydrolysis|increases reaction 12051674
C002615 benzo(c)phenanthrene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene]increases metabolic processing|increases reaction 8961944
C002615 benzo(c)phenanthrene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene]increases metabolic processing|increases reaction 8961944
C002615 benzo(c)phenanthrene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene]increases metabolic processing|increases reaction 8961944
C002615 benzo(c)phenanthrene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene]increases metabolic processing|increases reaction 8961944
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of EPHX1 mRNAincreases expression 15735009
D001564 Benzo(a)pyrene EPHX1 protein polymorphism affects the metabolism of and results in increased activity of Benzo(a)pyreneaffects metabolic processing|increases activity 15298956
D001564 Benzo(a)pyrene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of Benzo(a)pyrene]increases metabolic processing|increases reaction 8961944
D001564 Benzo(a)pyrene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Benzo(a)pyrene]increases metabolic processing|increases reaction 8961944
D001564 Benzo(a)pyrene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of Benzo(a)pyrene]increases metabolic processing|increases reaction 8961944
D001564 Benzo(a)pyrene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Benzo(a)pyrene]increases metabolic processing|increases reaction 8961944
C005465 benzothiazole benzothiazole results in increased expression of EPHX1 mRNAincreases expression 8951341
C032036 bromobenzene bromobenzene results in increased expression of EPHX1 mRNAincreases expression 12628495
D002104 Cadmium Cadmium results in increased expression of EPHX1 mRNAincreases expression 17327699
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of EPHX1 mRNAincreases expression 17327699
D002220 Carbamazepine Carbamazepine results in increased expression of EPHX1 mRNAincreases expression 17112801
D002220 Carbamazepine EPHX1 gene SNP affects the susceptibility to Carbamazepineaffects response to substance 19620853
C012227 carbamazepine epoxide [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamideaffects chemical synthesis|affects metabolic processing 15692831
C012227 carbamazepine epoxide [EPHX1 protein results in increased metabolism of carbamazepine epoxide] which results in increased chemical synthesis of 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamideincreases chemical synthesis|increases metabolic processing 15692831
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of EPHX1 mRNAdecreases expression 17484886
D002330 Carmustine Carmustine results in decreased expression of EPHX1 mRNAdecreases expression 15980968
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNAincreases expression 17851650
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNAincreases expression 18178546
C031180 chrysene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of chrysene]increases metabolic processing|increases reaction 8961944
C031180 chrysene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene]increases metabolic processing|increases reaction 8961944
C031180 chrysene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of chrysene]increases metabolic processing|increases reaction 8961944
C031180 chrysene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene]increases metabolic processing|increases reaction 8961944
D002994 Clofibrate Clofibrate results in decreased activity of EPHX1 proteindecreases activity 10528994
D003520 Cyclophosphamide Cyclophosphamide affects the expression of EPHX1 mRNAaffects expression 18246545
D003520 Cyclophosphamide Cyclophosphamide results in increased expression of EPHX1 mRNAincreases expression 18246545
D016572 Cyclosporine Cyclosporine results in decreased expression of EPHX1 mRNAdecreases expression 20106945
D015084 2,4-Dichlorophenoxyacetic Acid 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 proteinincreases activity 3032197
C014347 decitabine decitabine results in increased expression of EPHX1 mRNAincreases expression 19194470
C007262 deoxynivalenol deoxynivalenol results in decreased expression of EPHX1 mRNAdecreases expression 15371230
C061481 dibenzoylmethane dibenzoylmethane results in increased expression of EPHX1 mRNAincreases expression 17942926
C061481 dibenzoylmethane [sulforafan co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNAaffects cotreatment|increases expression 17942926
D002945 Cisplatin Cisplatin affects the expression of EPHX1 mRNAaffects expression 18246545
D002945 Cisplatin Cisplatin results in increased expression of EPHX1 mRNAincreases expression 18246545
C121718 dicyclanil dicyclanil results in increased expression of EPHX1 mRNAincreases expression 15664270
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in decreased activity of EPHX1 proteindecreases activity 10528994
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of EPHX1 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPHX1 mRNA]decreases reaction|increases expression 17854601
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNAaffects cotreatment|increases expression 18544905
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of EPHX1 mRNAincreases expression 17602206
19638242
20360939
D004052 Diethylnitrosamine [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of EPHX1 proteinaffects cotreatment|increases expression 20935162
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of EPHX1 mRNAincreases expression 15890375
C035318 diethylthiourea diethylthiourea results in increased expression of EPHX1 mRNAincreases expression 10190572
C035318 diethylthiourea diethylthiourea results in increased expression of EPHX1 proteinincreases expression 10190572
D015127 9,10-Dimethyl-1,2-benzanthracene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]increases metabolic processing|increases reaction 8961944
D015127 9,10-Dimethyl-1,2-benzanthracene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]increases metabolic processing|increases reaction 8961944
D015127 9,10-Dimethyl-1,2-benzanthracene EPHX1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthraceneaffects response to substance 15331171
D015127 9,10-Dimethyl-1,2-benzanthracene EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]increases metabolic processing|increases reaction 8961944
D015127 9,10-Dimethyl-1,2-benzanthracene EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]increases metabolic processing|increases reaction 8961944
D015127 9,10-Dimethyl-1,2-benzanthracene EPHX1 protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthraceneincreases response to substance 11323178
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of EPHX1 mRNAincreases expression 15890375
14600272
C032788 diphenylthiourea diphenylthiourea results in increased expression of EPHX1 mRNAincreases expression 10190572
C032788 diphenylthiourea diphenylthiourea results in increased expression of EPHX1 proteinincreases expression 10190572
D004317 Doxorubicin Doxorubicin results in increased expression of EPHX1 mRNAincreases expression 15205334
D004391 Dust Dust results in decreased expression of EPHX1 mRNAdecreases expression 17805423
C007366 erythritol anhydride EPHX1 gene polymorphism affects the susceptibility to erythritol anhydrideaffects response to substance 15036125
C007366 erythritol anhydride EPHX1 gene mutant form results in increased susceptibility to erythritol anhydrideincreases response to substance 12929123
D004958 Estradiol Estradiol affects the expression of EPHX1 mRNAaffects expression 14699072
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of EPHX1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of EPHX1 mRNAdecreases expression 16174780
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of EPHX1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EPHX1 mRNAaffects cotreatment|decreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of EPHX1 mRNAdecreases expression 16174780
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of EPHX1 mRNAincreases expression 16926038
D005027 Ethylene Oxide EPHX1 protein affects the metabolism of Ethylene Oxideaffects metabolic processing 11437638
D005027 Ethylene Oxide EPHX1 protein affects the metabolism of Ethylene Oxideaffects metabolic processing 11437638
D005038 Ethylnitrosourea Ethylnitrosourea results in increased expression of EPHX1 mRNAincreases expression 15954086
C017690 fenvalerate fenvalerate metabolite results in increased activity of EPHX1 proteinincreases activity 10630566
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of EPHX1 mRNAincreases expression 17317680
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of EPHX1 mRNAincreases expression 17070881
D005472 Fluorouracil EPHX1 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
D005472 Fluorouracil Fluorouracil results in increased expression of EPHX1 mRNAincreases expression 15205334
C056933 fumonisin B1 fumonisin B1 results in increased expression of EPHX1 mRNAincreases expression 16221962
D019833 Genistein Genistein results in increased expression of EPHX1 mRNAincreases expression 18847459
D005978 Glutathione Glutathione deficiency results in increased expression of EPHX1 mRNAincreases expression 15345336
C071834 glycidamide glycidamide results in increased expression of EPHX1 mRNAincreases expression 17822822
C071834 glycidamide glycidamide results in increased expression of EPHX1 proteinincreases expression 17822822
C010176 halofuginone halofuginone results in increased expression of EPHX1 mRNAincreases expression 17180598
D006581 Hexachlorobenzene Hexachlorobenzene results in increased expression of EPHX1 mRNAincreases expression 15159207
D006841 Hydrocarbons, Aromatic EPHX1 protein affects the metabolism of Hydrocarbons, Aromaticaffects metabolic processing 12359356
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNAaffects cotreatment|increases expression 18544905
D017258 Medroxyprogesterone Acetate ESR1 protein promotes the reaction [Medroxyprogesterone Acetate results in increased expression of EPHX1 protein]increases expression|increases reaction 20383792
D017258 Medroxyprogesterone Acetate Medroxyprogesterone Acetate results in increased expression of EPHX1 mRNAincreases expression 20383792
D017258 Medroxyprogesterone Acetate Medroxyprogesterone Acetate results in increased expression of EPHX1 proteinincreases expression 20383792
D008701 Methapyrilene Methapyrilene results in increased expression of EPHX1 mRNAincreases expression 15890375
D016566 Organoselenium Compounds Organoselenium Compounds results in increased activity of EPHX1 proteinincreases activity 17163488
D010126 Ozone Ozone results in decreased expression of EPHX1 mRNAdecreases expression 12763052
C023036 perfluorooctanoic acid perfluorooctanoic acid affects the expression of EPHX1 mRNAaffects expression 18281256
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of EPHX1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of EPHX1 mRNAincreases expression 19482888
D010634 Phenobarbital [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of EPHX1 proteinaffects cotreatment|increases expression 20935162
D010634 Phenobarbital Phenobarbital results in increased expression of EPHX1 mRNAincreases expression 16940010
D010672 Phenytoin EPHX1 gene polymorphism affects the susceptibility to Phenytoinaffects response to substance 19952982
D010672 Phenytoin EPHX1 protein results in increased metabolism of Phenytoinincreases metabolic processing 19952982
D010795 Phthalic Acids Phthalic Acids results in decreased expression of EPHX1 mRNAdecreases expression 15728792
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of EPHX1 mRNAincreases expression 15890375
C006253 pirinixic acid pirinixic acid results in increased expression of EPHX1 mRNAincreases expression 16221962
15375163
17426115
C006253 pirinixic acid PPARA protein affects the reaction [pirinixic acid results in increased expression of EPHX1 mRNA]affects reaction|increases expression 16221962
C006253 pirinixic acid pirinixic acid results in increased expression of EPHX1 mRNAincreases expression 15890375
D011084 Polycyclic Hydrocarbons, Aromatic EPHX1 gene polymorphism affects the susceptibility to Polycyclic Hydrocarbons, Aromaticaffects response to substance 15466980
15061915
D011084 Polycyclic Hydrocarbons, Aromatic EPHX1 protein polymorphism affects the susceptibility to Polycyclic Hydrocarbons, Aromaticaffects response to substance 15355699
D011084 Polycyclic Hydrocarbons, Aromatic EPHX1 protein polymorphism results in decreased metabolism of Polycyclic Hydrocarbons, Aromaticdecreases metabolic processing 15917149
D011084 Polycyclic Hydrocarbons, Aromatic EPHX1 protein polymorphism results in increased metabolism of Polycyclic Hydrocarbons, Aromaticincreases metabolic processing 15917149
C045950 propiconazole propiconazole affects the expression of EPHX1 mRNAaffects expression 17383973
C031280 pyrazole pyrazole results in increased expression of EPHX1 mRNAincreases expression 17945193
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNAaffects cotreatment|decreases expression 17639512
D011794 Quercetin Quercetin results in increased expression of EPHX1 mRNAincreases expression 18095365
C059514 resveratrol resveratrol results in increased expression of EPHX1 mRNAincreases expression 11279601
C488333 Ro 65-7199 Ro 65-7199 results in increased expression of EPHX1 mRNAincreases expression 14610520
C488334 Ro 66-0074 Ro 66-0074 results in increased expression of EPHX1 mRNAincreases expression 14610520
C009250 sevoflurane sevoflurane affects the expression of EPHX1 mRNAaffects expression 15967596
D020058 Styrene EPHX1 gene polymorphism affects the susceptibility to Styreneaffects response to substance 14751678
D020058 Styrene Styrene results in increased expression of EPHX1 mRNAincreases expression 16418063
C013690 styrene oxide CYP3A12 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide]affects hydrolysis|increases reaction 12051674
C013690 styrene oxide EPHX1 protein affects the hydrolysis of styrene oxideaffects hydrolysis 11076696
C013690 styrene oxide EPHX1 protein affects the metabolism of and results in decreased activity of styrene oxideaffects metabolic processing|decreases activity 12694745
C013690 styrene oxide EPHX1 protein results in increased hydrolysis of styrene oxideincreases hydrolysis 17151961
C013690 styrene oxide CYP1A1 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide]affects hydrolysis|increases reaction 12051674
C013690 styrene oxide CYP2B1 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide]affects hydrolysis|increases reaction 12051674
C013690 styrene oxide CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide]affects hydrolysis|increases reaction 12051674
C013690 styrene oxide CYP3A12 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide]affects hydrolysis|increases reaction 12051674
C016766 sulforafan [sulforafan co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNAaffects cotreatment|increases expression 17942926
C016766 sulforafan sulforafan results in increased expression of EPHX1 mRNAincreases expression 17942926
C446685 systhane systhane affects the expression of EPHX1 mRNAaffects expression 17383973
D015085 2,4,5-Trichlorophenoxyacetic Acid 2,4,5-Trichlorophenoxyacetic Acid results in increased activity of EPHX1 proteinincreases activity 3032197
D013629 Tamoxifen Tamoxifen affects the expression of EPHX1 mRNAaffects expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of EPHX1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EPHX1 mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNAincreases expression 15328365
15800033
16960034
16611356
18163543
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNAincreases expression 16960034
C019107 tetramethylthiourea tetramethylthiourea results in increased expression of EPHX1 mRNAincreases expression 10190572
C019107 tetramethylthiourea tetramethylthiourea results in increased expression of EPHX1 proteinincreases expression 10190572
D013844 Thiazoles Thiazoles results in increased expression of EPHX1 mRNAincreases expression 8951341
D014303 Trinitrotoluene Trinitrotoluene affects the expression of EPHX1 mRNAaffects expression 21346803
D014315 Triterpenes Triterpenes results in increased expression of EPHX1 mRNAincreases expression 18544911
C025643 vinclozolin vinclozolin affects the expression of EPHX1 mRNAaffects expression 19015723
D014859 Warfarin EPHX1 gene SNP affects the susceptibility to Warfarinaffects response to substance 15900282
D015032 Zinc Zinc results in increased expression of EPHX1 mRNAincreases expression 17074742
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of EPHX1 mRNAincreases expression 17074742
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6214745880
MESH:D000014 Abnormalities, Drug-Induced marker/mechanism 2336087
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 26.197525203
MESH:D000014 Abnormalities, Drug-Induced Carbamazepine 26.198986270
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 26.196734493
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 26.196195326
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 26.196195326 9677735 10563481 3425630 8986270 9118846
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 26.1914514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 26.197525203
MESH:D000138 Acidosis Ammonium Chloride 7.6018287403
MESH:D000138 Acidosis Zinc Sulfate 7.607265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.0117505938
MESH:D000169 Acrodermatitis Zinc 4.4917202136 17190629 16889938
MESH:D058186 Acute Kidney Injury Cisplatin 6.1412690470 17670903 15814532
MESH:D058186 Acute Kidney Injury resveratrol 6.1416538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.2818653653
MESH:D000230 Adenocarcinoma 9,10-Dimethyl-1,2-benzanthracene 24.9312844480 10697514
MESH:D000230 Adenocarcinoma arsenic trioxide 24.9319825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 24.9320464547 20127859
MESH:D000230 Adenocarcinoma Cisplatin 24.9311798837 17638652
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 24.9316033868
MESH:D000230 Adenocarcinoma Doxorubicin 24.9317418594
MESH:D000230 Adenocarcinoma Estradiol 24.9311473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 24.9314692618
MESH:D000230 Adenocarcinoma Fluorouracil 24.9317638652
MESH:D000230 Adenocarcinoma Genistein 24.9311473722
MESH:D000236 Adenoma 2-Acetylaminofluorene 26.3910737359
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 26.3916176798
MESH:D000236 Adenoma 9,10-Dimethyl-1,2-benzanthracene 26.3911376689
MESH:D000236 Adenoma Benzo(a)pyrene 26.396695378
MESH:D000236 Adenoma Diethylnitrosamine 26.396695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 26.3919555203
MESH:D000236 Adenoma Ethylnitrosourea 26.396695378
MESH:D000236 Adenoma resveratrol 26.3915688382
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.076705139
MESH:D018248 Adenoma, Liver Cell dicyclanil 23.1417162532
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 23.1419061943 17162532 17620307 19052882 18056438 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 23.1417620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 23.1416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 23.1416835633
MESH:D011125 Adenomatous Polyposis Coli dibenzoylmethane 8.0917942926
MESH:D011125 Adenomatous Polyposis Coli sulforafan 8.0917942926
MESH:D000382 Agricultural Workers' Diseases 2,4-Dichlorophenoxyacetic Acid 4.2416132792
MESH:D000419 Albuminuria Doxorubicin 3.6721441931
MESH:D000544 Alzheimer Disease Ozone 4.8315513908
MESH:D000544 Alzheimer Disease resveratrol 4.8316162502 16183991
MESH:D000544 Alzheimer Disease Zinc 4.8316410023 17119284 16580781 16325427
MESH:D000686 Amyloidosis Diethylstilbestrol 3.6015469931
MESH:D000740 Anemia Fluorouracil 5.9916511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 5.9911748828
MESH:D000741 Anemia, Aplastic Benzene 3.6214761424 11369114 17661222
MESH:D000743 Anemia, Hemolytic Quercetin 3.4117084956
MESH:D000755 Anemia, Sickle Cell Zinc 4.0216916123
MESH:D000799 Angioedema Acetaminophen 2.9110982225
MESH:D000860 Anoxia Zinc Sulfate 4.117265320
MESH:D001008 Anxiety Disorders vinclozolin 2.8819015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.1819183758
MESH:D001161 Arteriosclerosis Cyclophosphamide 7.2115014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.2111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.2115885639
MESH:D001169 Arthritis, Experimental resveratrol 5.2117115116
MESH:D001172 Arthritis, Rheumatoid Ozone 2.2715570426
MESH:D001249 Asthma Ozone 3.8617854713 16373670
MESH:D001249 Asthma Zinc 3.8617085522
MESH:D001260 Ataxia Telangiectasia Quercetin 4.0615336622
MESH:D050197 Atherosclerosis Asbestos 10.6318795166
MESH:D050197 Atherosclerosis Cadmium 10.6315687053
MESH:D050197 Atherosclerosis Phenytoin 10.6315136057
MESH:D050197 Atherosclerosis resveratrol 10.6316873680 17967414
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 3.6820106747
MESH:D001321 Autistic Disorder Acetaminophen 2.3018445737
MESH:D001321 Autistic Disorder Glutathione 2.3019267885 16917939 19056591 18929414
MESH:D001327 Autoimmune Diseases Quercetin 8.3019761891
MESH:D001327 Autoimmune Diseases sulforafan 8.3019761891
MESH:D001714 Bipolar Disorder Carbamazepine 3.5817594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.1916206674
MESH:D001778 Blood Coagulation Disorders Clofibrate 15.1919483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.1919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.1912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1015746008
MESH:D001855 Bone Marrow Diseases Benzene 4.3016183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 8.9714601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 8.9714601052
MESH:D001927 Brain Diseases Ethylnitrosourea 4.0614991843
MESH:D001930 Brain Injuries Zinc 3.8017109824
MESH:D002545 Brain Ischemia resveratrol 3.3817600658
MESH:D001932 Brain Neoplasms 1,3-butadiene 18.8116860786
MESH:D001932 Brain Neoplasms Carmustine 18.8116187019
MESH:D001932 Brain Neoplasms Doxorubicin 18.8117150277
MESH:D001932 Brain Neoplasms Ethylene Oxide 18.8112562636
MESH:D001932 Brain Neoplasms Ethylnitrosourea 18.8116357521 16651633 15144691 16436596 18412241
MESH:D001943 Breast Neoplasms 1,3-butadiene 25.7411921183 12165863
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 25.7411921183
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 25.7420146248
MESH:D001943 Breast Neoplasms 9,10-Dimethyl-1,2-benzanthracene 25.7415565634 16153821 17127718 18840765 20435547
MESH:D001943 Breast Neoplasms Ascorbic Acid 25.7416443354
MESH:D001943 Breast Neoplasms Benzene 25.7411921183 17162533
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 25.7420146248 17474063
MESH:D001943 Breast Neoplasms Cisplatin 25.7419526202 18382427
MESH:D001943 Breast Neoplasms Cyclophosphamide 25.7417020986 18234424 15136595 11325840 15093573 17388661 16978400 12006526 18323546
MESH:D001943 Breast Neoplasms decitabine 25.7418320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 25.7417474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 25.7417129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 25.7416096432 15692762 16264153 15567936 18628466 16826403 18695136 17426702 15994142 19526202 15136595 15668708 18382427 15634643 15939500 15993339 16935488 17983394 18234424 11325840 16115903 16595493 17369602 16322301
MESH:D001943 Breast Neoplasms Estradiol 25.7412948864 17261762 17289903 16675129 18497071 17018787 14630087 19861407
MESH:D001943 Breast Neoplasms Ethylene Oxide 25.7411921183 17162533
MESH:D001943 Breast Neoplasms Fluorouracil 25.7419217205 16110121 15136595 18357371 16557594 16595493 18608205
MESH:D001943 Breast Neoplasms Genistein 25.7416873071 16541309 17200150
MESH:D001943 Breast Neoplasms Hexachlorobenzene 25.7412709520 15061365
MESH:D001943 Breast Neoplasms Organoselenium Compounds 25.7415833885 16155795
MESH:D001943 Breast Neoplasms Quercetin 25.7418628248
MESH:D001943 Breast Neoplasms resveratrol 25.7416393696 17651959 17534123
MESH:D001943 Breast Neoplasms Styrene 25.7415986119
MESH:D001943 Breast Neoplasms Tamoxifen 25.7420135344 19115204 20065188 18351453 19066611 19155303 17242785 15668708 16818667 19487384 18821012 18815881 18984771 19084267 20005174 19011961 18997820 19142967 11161223 18629630 17440819 19221464 19059307 19189212 19289846 19189210 19288272 15565566 20859285 16202921 19410462 20544844 16273361 17049068 19244106 18855134 18425577 17893378 20390343 21138602 16873071 19103187 21152245 17261762 19200415
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 25.7420435547
MESH:D016535 Bronchial Hyperreactivity Ozone 2.9318315731 17626835 18417511 14754758 15516495 16777450 19059883
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.4711589617
MESH:D002100 Cachexia Ozone 3.8316183385
MESH:D002105 Cadmium Poisoning Quercetin 4.6116962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.893786805 15700767 16050911 16227642 18705752 15721981 16097048 15673190 16011737 16124888 16192424 10355542
MESH:D002276 Carcinoid Tumor Doxorubicin 9.2716051944
MESH:D002276 Carcinoid Tumor Fluorouracil 9.2716051944
MESH:D002277 Carcinoma Dimethylnitrosamine 9.6119555203
MESH:D002277 Carcinoma Fluorouracil 9.6117121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 9.6116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.6119066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 46.7616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 46.7616705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 46.7617761372 6705139 3581430 10737359 3084413
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 46.763084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 46.7621507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 46.7615553829 16217749 11135700 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 46.7618788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 46.7617982673
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 46.7619701751
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 46.7617162532
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 46.7619519916 16878318 18056438 20727157 19418558 16569478 18978308 20514400 19394651 18210153 17428255 19919837 20084675 19701751 18971187 16935385 20101231 20214788 19822196 3084413 20512989 19208518 16540662 18393292 11831363 16502159 10737359 18788625 19335982 19539802 16698587 16328049 20432363 19052882 19383236 20524982 21159647 17173139 3581430 17761372 18691550 16288022 18494052 19171122 19107877 20007298 17162532 17978847 10672840 18506893 16779866 17138121 16830150 17055752 16807293 18665156 16681979 20935162 18785209
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 46.7616924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 46.7618059187 16234567 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 46.7616924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 46.7618930000 16332177 17971768 17045692 16799960 17088986
MESH:D006528 Carcinoma, Hepatocellular Genistein 46.7616924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 46.7620007298 20935162 17173139 6705139 1701930
MESH:D006528 Carcinoma, Hepatocellular Quercetin 46.7612508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 46.7616227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 46.7616924424
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 8.4616152834
MESH:D018827 Carcinoma, Lewis Lung resveratrol 8.4616675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.6316685392 12023789
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0617234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.9419014326
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 7.7616201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 7.761485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 7.7618695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.3012490120
MESH:D002294 Carcinoma, Squamous Cell 9,10-Dimethyl-1,2-benzanthracene 29.3211376689
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 29.3220419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 29.3217066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell decitabine 29.3219215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 29.3216033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 29.326189445
MESH:D002294 Carcinoma, Squamous Cell erythritol anhydride 29.3210925838
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 29.3216757204 16280240 17066447 18986760
MESH:D002294 Carcinoma, Squamous Cell Glutathione 29.3217015178
MESH:D002294 Carcinoma, Squamous Cell resveratrol 29.3216227395
MESH:D002294 Carcinoma, Squamous Cell Zinc 29.3216543248
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 2.8017572228
MESH:D006332 Cardiomegaly Quercetin 4.8019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 4.8018670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 2.8716612575 17308081 16278810 17131338 16952015 17351982 15811867 17519947 17924179 15476868 15792986 16364871 17974986 17329180 17007740 15505089 17382496 16109756 17928571 16269455 16242529 18627295 16455267 16651473 16731534
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5316243910 17334414
MESH:D002318 Cardiovascular Diseases Genistein 8.2716332659
MESH:D002318 Cardiovascular Diseases resveratrol 8.2715458977
MESH:D002318 Cardiovascular Diseases Zinc 8.2716936243
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 8.8414694615
MESH:D002386 Cataract Acetaminophen 8.8410977129
MESH:D002386 Cataract Trinitrotoluene 8.8415817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 21.306135515
MESH:D002471 Cell Transformation, Neoplastic Cadmium 21.3017332340
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 21.301399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 21.3012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 21.3017174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 21.3018566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 21.3016003739
MESH:D002493 Central Nervous System Diseases Phenobarbital 8.704080065
MESH:D002493 Central Nervous System Diseases Phenytoin 8.704080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.0517160924
MESH:D002543 Cerebral Hemorrhage Warfarin 4.9711061249
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 6.6719052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 6.6716835633
MESH:D002779 Cholestasis Cyclosporine 9.1319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 9.1316105132 11677210 17681005 17110522 16919318 17333356 15861022
MESH:D002779 Cholestasis pirinixic acid 9.1319176532
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 4.9511748493
MESH:D002971 Cleft Lip Phenytoin 3.582227380
MESH:D002972 Cleft Palate Phenytoin 4.512227380 3877104 1687470 10789828 6862529 6856622
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.5112621046 15340226 16354765 8697196 15668235
MESH:D003092 Colitis resveratrol 3.2516474422
MESH:D003103 Coloboma Phenytoin 4.319212184
MESH:D003110 Colonic Neoplasms arsenite 10.2915037631
MESH:D003110 Colonic Neoplasms decitabine 10.2917616700
MESH:D003110 Colonic Neoplasms Fluorouracil 10.2915001691 17287894 17725105 17169374 16510598 16340194 18772588 17018589 17172411 17016597
MESH:D003110 Colonic Neoplasms Genistein 10.2917182828
MESH:D003110 Colonic Neoplasms Quercetin 10.2919440933 11134977 19056647 17148506 16640504 17191121 15741050
MESH:D003110 Colonic Neoplasms resveratrol 10.2916338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 7.8920501625
MESH:D015179 Colorectal Neoplasms Cisplatin 7.8915273666
MESH:D015179 Colorectal Neoplasms decitabine 7.8918981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 7.8918802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 7.8918383874 15148649 16282729 18509181 16331619 17401013 18802399 17454858 17695437 14970324 20501625 17094418 16524972 16303861 17594712 17255274 18288408 16391804 18949393 17016601 18448328 15289873
MESH:D015179 Colorectal Neoplasms Quercetin 7.8918095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 7.8916550006
MESH:D003139 Common Cold Ascorbic Acid 4.5417323712
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 15.7315095906
MESH:D000013 Congenital Abnormalities Phenytoin 15.7310627286
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 15.7314669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 15.7315095906
MESH:D003327 Coronary Disease resveratrol 3.0916507316
MESH:D023903 Coronary Restenosis arsenic trioxide 8.6012609071
MESH:D023903 Coronary Restenosis Warfarin 8.6012872399
OMIM:122700 COUMARIN RESISTANCE Warfarin 4.9620579077 20497562
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 7.0510525206
MESH:D019465 Craniofacial Abnormalities Benzene 7.0515643154
MESH:D019465 Craniofacial Abnormalities Carbamazepine 7.059014606
MESH:D019465 Craniofacial Abnormalities Phenytoin 7.059212184 19952982 8986270
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.0515322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Zinc 7.0519302082
MESH:D003456 Cryptorchidism Diethylstilbestrol 8.4616002989 12952375
MESH:D003456 Cryptorchidism vinclozolin 8.4614966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 13.6618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 13.6618551238
MESH:D003490 Cyanosis Trinitrotoluene 13.6618551238
MESH:D003550 Cystic Fibrosis Glutathione 3.6919747007
MESH:D003556 Cystitis Cyclophosphamide 4.0618483878 18372110 18295254 16413132 11948286 12388444 17979934 18093676 12161096 15276878 17010015 16989017 16651033 10498854 15643279 18433785 18710439 12913760 10700343 16614059
MESH:D007644 Darier Disease Fluorouracil 3.8816733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.2415213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4619031437
MESH:D003872 Dermatitis Benzene 3.8715902427
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 5.1916882537
MESH:D003876 Dermatitis, Atopic pirinixic acid 5.1918249437
MESH:D003920 Diabetes Mellitus Zinc 3.4116479319
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 9.5810990075 15331540 11751995
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 9.5819496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 9.5816873680
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 4.8918772604
MESH:D003922 Diabetes Mellitus, Type 1 Warfarin 4.8918772604
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 7.3716506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.3720387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 7.3716647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.3717107852
MESH:D003928 Diabetic Nephropathies Estradiol 15.0019279558
MESH:D003928 Diabetic Nephropathies resveratrol 15.0016286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 15.0019279558
MESH:D003928 Diabetic Nephropathies Warfarin 15.0012644472
OMIM:607208 DRAVET SYNDROME Carbamazepine 9.4311748493
OMIM:607208 DRAVET SYNDROME Phenytoin 9.4311748493
MESH:D003875 Drug Eruptions Phenytoin 10.0115024534
MESH:D003875 Drug Eruptions Warfarin 10.0114723717
MESH:D004342 Drug Hypersensitivity Carbamazepine 3.7720216337 16538176 15057820 16538175
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 40.0418551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 40.0421346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2-nitropropane 40.0416445897 15804453 20517888
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 40.0421346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 40.0419923254 10915739 14550746 12705907 2444490 11739529 12594235 18071297 10774834 16177239 12153990 16109766 12540782 19085960 16393943 16081117 19370779 19416960 11529661 11461765 17562736 15968718 16485898 11834606 10663392 16227642 19164858 16781746 15619225 11743745 17522070 14986274 19420014 17906064 12392966 18713872 12958197 14725611 11421492 11287661 19739265
MESH:D056486 Drug-Induced Liver Injury bromobenzene 40.0410092053 12628495
MESH:D056486 Drug-Induced Liver Injury Carbamazepine 40.0417465707
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 40.0416177239 3732212 16227642 7120509 17522070 6623471 19085960 6884620 10915739 3786805 21278145 15998439 4309450 7179309 2869522 15027814 19336974 10092053 9327722 7440962 15968718 11566570
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 40.0417851650
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 40.0419107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 40.048172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 40.0417416283
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 40.0416221962
MESH:D056486 Drug-Induced Liver Injury pyrazole 40.0412499123
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 40.0420420201
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 40.0418551238 21346803
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1719426721
MESH:D004362 Drug Toxicity Carbamazepine 13.7220216337
MESH:D004362 Drug Toxicity Cisplatin 13.7215033597 12231392 19839026 12649298
MESH:D004362 Drug Toxicity Doxorubicin 13.7218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 13.7211462148
MESH:D050171 Dyslipidemias Clofibrate 3.3516707586
MESH:D004421 Dystonia Phenobarbital 3.151851702
MESH:C538011 Eales disease Ascorbic Acid 4.549068938
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.0518357618
MESH:D004487 Edema perfluorooctanoic acid 9.7917259670 12083418
MESH:D004487 Edema pirinixic acid 9.7912083418
MESH:D004487 Edema resveratrol 9.798985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.7912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 2.9715322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Carbamazepine 19.6317654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.6312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 19.6317654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 19.6317872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.6319031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.1819294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 8.8616402032
MESH:D004714 Endometrial Hyperplasia Genistein 8.8616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 16.2816804899 15700306
MESH:D016889 Endometrial Neoplasms Doxorubicin 16.2817359293
MESH:D016889 Endometrial Neoplasms Estradiol 16.2819148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 16.2811473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 16.2816202921 20544844 17893378 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.2110568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.2218037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 3.9517923197
MESH:D004802 Eosinophilia Cyclophosphamide 3.3411006010
MESH:D004816 Epidermal Necrolysis, Toxic Carbamazepine 8.8216538176 18855540 19915237 20485159 16415921
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 8.8220235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 5.301399206 6251365
MESH:D004831 Epilepsies, Myoclonic Carbamazepine 8.2217275665
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 8.223659116
MESH:D004828 Epilepsies, Partial Carbamazepine 11.7817116037 16628512 15008574
MESH:D004828 Epilepsies, Partial Phenobarbital 11.7811558140 3922381
MESH:D004828 Epilepsies, Partial Phenytoin 11.7811558140 17116037
MESH:D004827 Epilepsy Carbamazepine 7.9717178248 20417680 18234410 17465707 7988514 821787 19700373 19439326 19620853 9014606
MESH:D004827 Epilepsy Phenobarbital 7.9720417680
MESH:D004827 Epilepsy Phenytoin 7.9711434505 20417680 821787
MESH:D004832 Epilepsy, Absence Phenobarbital 2.756401628
MESH:D017029 Epilepsy, Complex Partial Carbamazepine 14.417750514
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 14.417750514
MESH:D017029 Epilepsy, Complex Partial Phenytoin 14.417750514
MESH:D004830 Epilepsy, Tonic-Clonic Carbamazepine 12.7715276670 3659116
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 12.773659116
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 12.773659116
MESH:D004916 Erythromelalgia Carbamazepine 4.8119549232
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1816302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.7412903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 12.7416530937
MESH:D004938 Esophageal Neoplasms Cisplatin 12.7415173087 16481741 17638652 16785472 15464296
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 12.7417016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 12.7415173087 17638652 16337965 16481741 16785472
MESH:D004938 Esophageal Neoplasms Zinc 12.7416543248
MESH:D005076 Exanthema Carbamazepine 4.5520485159
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.2811564622
MESH:D005234 Fatty Liver arsenic trioxide 33.5715073043
MESH:D005234 Fatty Liver arsenite 33.5718296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 33.5719224547 17595544 61145 16239168 15959796 16045604 12795759 12631006
MESH:D005234 Fatty Liver Clofibrate 33.5719224547
MESH:D005234 Fatty Liver Cyclosporine 33.5719224547
MESH:D005234 Fatty Liver Diethylnitrosamine 33.5720387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 33.5715345470
MESH:D005234 Fatty Liver pirinixic acid 33.5719236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 33.5714986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.0715751030 16513791 16002989 16534752 16611131
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.0716709447
MESH:D005313 Fetal Death Phenytoin 7.7810627286
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 7.7811858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.6114745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.4119069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.4119069698
MESH:D005355 Fibrosis arsenite 18.4218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 18.4218705752
MESH:D005355 Fibrosis Cyclosporine 18.4212639820 12168785
MESH:D005355 Fibrosis Quercetin 18.4219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 18.4220067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.3916904648
MESH:D005756 Gastritis Acetaminophen 8.0916983495
MESH:D005756 Gastritis Zinc 8.0917241300
MESH:D006471 Gastrointestinal Hemorrhage Warfarin 5.7811794436
MESH:D005776 Gaucher Disease Warfarin 5.0812359135
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.0216973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.3716417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.0316452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 9.878708960
MESH:D005885 Gingival Hyperplasia Phenytoin 9.879029455
MESH:D019214 Gingival Overgrowth Phenytoin 5.3014659971 16390469
MESH:D005909 Glioblastoma Carmustine 15.2316187019
MESH:D005909 Glioblastoma Doxorubicin 15.2317150277
MESH:D005909 Glioblastoma Ethylnitrosourea 15.2316436596
MESH:D005909 Glioblastoma Genistein 15.2316598420
MESH:D005909 Glioblastoma Quercetin 15.2319804834
MESH:D005910 Glioma 1,3-butadiene 10.2715814359
MESH:D005910 Glioma Ethylnitrosourea 10.2718412241 16357521 16651633
MESH:D005910 Glioma Fluorouracil 10.2716145905
MESH:D005910 Glioma Quercetin 10.2717643826
MESH:D018316 Gliosarcoma Cyclophosphamide 4.6011389073
MESH:D005922 Glomerulonephritis, IGA deoxynivalenol 4.2516524712 15173396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6610696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.1416376943 15172196 11014644
MESH:D006130 Growth Disorders Zinc 3.3017217573
MESH:D006258 Head and Neck Neoplasms Cisplatin 12.8815102660 15464296
MESH:D006258 Head and Neck Neoplasms decitabine 12.8819215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 12.8815692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 12.8815162350 15102660 18337622
MESH:D034381 Hearing Loss Cisplatin 7.8219898482
MESH:D034381 Hearing Loss Styrene 7.8217420221
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6315464296
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 7.8216080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.8220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.8211294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 2.8016244371 17875725 18674790 16495754 16707910 16879835 16144979 18006777 12587719 16244372 16330681 14766674 17888722
MESH:D006333 Heart Failure Doxorubicin 8.1417481944
MESH:D006333 Heart Failure pirinixic acid 8.1420558911
MESH:D006333 Heart Failure Zinc 8.1417162251
MESH:D006335 Heart Injuries Zinc 4.8417074742
MESH:D016481 Helicobacter Infections Zinc 3.6817241300
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 4.396705139
MESH:D006394 Hemangiosarcoma 1,3-butadiene 10.7310930038 2208121
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 10.736705139
MESH:D006394 Hemangiosarcoma Doxorubicin 10.7315692506
MESH:D006402 Hematologic Diseases Benzene 3.8016183116
MESH:D006406 Hematoma Warfarin 5.7817493413
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.5015720958
MESH:D006467 Hemophilia A Cyclophosphamide 4.3911918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 7.7311000095
MESH:D006470 Hemorrhage Warfarin 7.7318429757
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.6014986274
MESH:D006505 Hepatitis Carbon Tetrachloride 2.7319110552 19900420
MESH:D006527 Hepatolenticular Degeneration Zinc 8.3517276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 8.3517063115
MESH:D006529 Hepatomegaly fenvalerate 37.2115602828
MESH:D006529 Hepatomegaly fumonisin B1 37.2116221962
MESH:D006529 Hepatomegaly perfluorooctanoic acid 37.213609246
MESH:D006529 Hepatomegaly Phenobarbital 37.2116109766
MESH:D006529 Hepatomegaly pirinixic acid 37.2118467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly propiconazole 37.2117178689 17178688
MESH:D006529 Hepatomegaly systhane 37.2117178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 37.2115340226 16120746 12621046
MESH:D006529 Hepatomegaly Trinitrotoluene 37.2115817613
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.0616490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.1015709030
MESH:D006561 Herpes Simplex resveratrol 3.2816876885
MESH:D006689 Hodgkin Disease Cisplatin 7.9016200630 16170182
MESH:D006689 Hodgkin Disease Cyclophosphamide 7.9017606976 16135485
MESH:D006689 Hodgkin Disease Doxorubicin 7.9018501091 17606976 15147373
MESH:D019584 Hot Flashes Estradiol 2.8317088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.118697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 5.3616870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 5.3612083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6216899240
MESH:D006937 Hypercholesterolemia resveratrol 3.1817188708
MESH:D006943 Hyperglycemia pirinixic acid 6.5420558911
MESH:D006943 Hyperglycemia Quercetin 6.5411834736 18262572
MESH:D020138 Hyperhomocysteinemia Carbamazepine 7.2610459572
MESH:D020138 Hyperhomocysteinemia Phenytoin 7.2610459572
MESH:D006949 Hyperlipidemias resveratrol 3.1916873680
MESH:D006965 Hyperplasia Carbamazepine 13.5118773962
MESH:D006965 Hyperplasia Diethylstilbestrol 13.5112960047 14722030
MESH:D006965 Hyperplasia halofuginone 13.5111874485
MESH:D006973 Hypertension Benzene 8.5317940673
MESH:D006973 Hypertension Cyclosporine 8.5310903974
MESH:D006973 Hypertension Quercetin 8.5318356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.5318850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.1915338365
MESH:D006976 Hypertension, Pulmonary Warfarin 4.1012359135
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.4817488730
MESH:D007021 Hypospadias Diethylstilbestrol 8.2716002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.2716945680 16569931
MESH:D007022 Hypotension Zinc Sulfate 3.637265320
MESH:D007154 Immune System Diseases Cyclophosphamide 4.4016076520
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 3.7517600658
MESH:D007246 Infertility Diethylstilbestrol 3.4815036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.6112013081
MESH:D007248 Infertility, Male 2,4-Dichlorophenoxyacetic Acid 17.6612948887
MESH:D007248 Infertility, Male Cyclophosphamide 17.667193160 16517039
MESH:D007248 Infertility, Male decitabine 17.6617581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 17.6617937319
MESH:D007248 Infertility, Male Trinitrotoluene 17.6612150543
MESH:D007248 Infertility, Male vinclozolin 17.6616467254
MESH:D007249 Inflammation Diethylnitrosamine 9.8218785209
MESH:D007249 Inflammation perfluorooctanoic acid 9.8212083418
MESH:D007249 Inflammation resveratrol 9.8216366677
MESH:D007249 Inflammation Tamoxifen 9.8219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 9.8212200463 12878042
MESH:D007251 Influenza, Human Quercetin 8.1216624496
MESH:D007251 Influenza, Human resveratrol 8.1216624496
MESH:D007333 Insulin Resistance Estradiol 4.9716627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 4.9716306350
MESH:D007511 Ischemia Zinc 3.7416584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.5016580747
MESH:D007627 Keloid Quercetin 4.0617086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.5115604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.2115464296
MESH:D007674 Kidney Diseases Acetaminophen 27.0215629191 12587719
MESH:D007674 Kidney Diseases Cadmium 27.0216322080 16226777 16962696
MESH:D007674 Kidney Diseases Cadmium Chloride 27.0216962696
MESH:D007674 Kidney Diseases Cisplatin 27.0219839026 15190930 12649298 12231392 18289764
MESH:D007674 Kidney Diseases Cyclosporine 27.028314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 27.0215699352 16775033 15369732
MESH:D007674 Kidney Diseases Estradiol 27.0215618244
MESH:D007674 Kidney Diseases Quercetin 27.0216962696
MESH:D007674 Kidney Diseases Zinc 27.0216960431
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.4116707910
MESH:D007676 Kidney Failure, Chronic Zinc 7.4116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 27.6716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 27.6716705839
MESH:D007680 Kidney Neoplasms Cyclosporine 27.6712371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 27.6715003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 27.6715610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 27.6717379185
MESH:D007680 Kidney Neoplasms Fluorouracil 27.6716985049
MESH:D007680 Kidney Neoplasms Tamoxifen 27.6718625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.8711231351
MESH:D007859 Learning Disorders Diethylstilbestrol 7.0517184923
MESH:D007859 Learning Disorders sevoflurane 7.0519212262
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 3.5015237267
MESH:D007938 Leukemia 1,3-butadiene 21.1916155477
MESH:D007938 Leukemia arsenic trioxide 21.1915070760
MESH:D007938 Leukemia Benzene 21.1914694614 17119257 18335105 15935818
MESH:D007938 Leukemia Cyclophosphamide 21.1910602166
MESH:D007938 Leukemia decitabine 21.1918980019 19235587
MESH:D007938 Leukemia Genistein 21.1918980019 17468513
MESH:D007938 Leukemia Quercetin 21.1917468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2216085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.0117296974 17802794 17658394 18587576 17008537 18172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 2.9617077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.3916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.1914633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 6.1910373061
MESH:D007951 Leukemia, Myeloid arsenic trioxide 11.2819077051
MESH:D007951 Leukemia, Myeloid Benzene 11.2817506065
MESH:D007951 Leukemia, Myeloid decitabine 11.2817236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.6120471514 17050201 19850784 16467208 16968895
MESH:D015470 Leukemia, Myeloid, Acute Benzene 4.6119478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.6119387464 18460780 18704418 19010910 18206229 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.5318055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.5615213294 16331271 17649720 17869043 19075265 16966277 12712474 15622746 19035177 12018890 9834237 19225113 16891316 17217047 12679006 15336539 16823087 11161223 17712046 15748426 19642359 16330433 17107899 11468182 16112521
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 5.5616087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.4716882451
MESH:D007970 Leukopenia Cyclophosphamide 4.0511830472 10052129
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 9.908812269
MESH:D007984 Leydig Cell Tumor vinclozolin 9.9016417039
MESH:D008064 Lipidoses Tamoxifen 2.4617567588 15342952
MESH:D054068 Livedo Reticularis Warfarin 5.7818280355
MESH:D008103 Liver Cirrhosis arsenite 14.4218296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.4217174718 16943688 17157831 21278145 16221502 11408273 16239168 17334410 11903743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 14.4220032147 18407596 18522880 19638242 18665156
MESH:D008103 Liver Cirrhosis halofuginone 14.4217180598
MESH:D008103 Liver Cirrhosis Phenobarbital 14.4221047994
MESH:D008106 Liver Cirrhosis, Experimental 1,3-dimethylthiourea 15.7211682029
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 15.7218395095 18054572 12667390 15818738 12632514 18412020 18156304 17761835 15893842 14748882 18317297 18210741 16011737 18395914 17721639 15338365 18339082 18472332 12958196 17714472 11481614 16248980 13678700 18251166 12741479 12666154 12632512 18376398 17565644 17823541 18420326 16015684 17557913 14716496 18205269 12445418 17640975 17708605 18279442 18277467 18705752 17805973 15876570 17869086 16116963 17900296 12586293 15931870 10355542 16638106 15996030 12649538 12546737 14620537 12609069 16033810 15123356 16097048 15673190 18006644 17525996 15052691 18429990 17698563 15650968 15925388 20821823 14512876 17976157 15370692 17766677 17481882 12898905 18472094 14716833 17922224 15057751 16136751 18263696 12389079 17631135 17944888 18166357 18418968 14724832 15959796 16027843 16192424 15362042 18481824 12445421 18187930 15730626
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 15.7217640959 18364076 15842777 15369754 15733078 15504291 16270385 15383259 15366600 15723089 18371158 18637143 17534399 17203207 12925901 16009107 15798949 17724770 15161499 16627068 12918455 16603200 15339415 15577212 15086199 15081153 15864749 18239293 15067225 14643895 16042886 14726149 15942678 16570917 18210741 15744066 17719030 15793283 15479170 15763062 15492853 15571005 17666798 17201889 16544323 18567088 14659978 14568256 15298665 17432682 17465448 16169303 14709902 17198567 17881167 15591649 17196135 18629640 17348192 15099470 18672772 17036385 18237412 15138612 18095165
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 15.7216595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 15.7214659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 15.7217823541
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 15.7216489207 11172339 12175628 18458672 14739098
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 15.7215474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 15.7212741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 15.7218564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 15.7212878042
MESH:D008107 Liver Diseases Acetaminophen 11.1416610002 16611625 19784758 12587719 19460945 11587558 12969438 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 11.1416246199 16964402 15720792 15830285 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 11.1417034775
MESH:D008107 Liver Diseases Phenobarbital 11.1419363144
MESH:D008107 Liver Diseases Phenytoin 11.1414986274
MESH:D008107 Liver Diseases propiconazole 11.1419363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 11.5616871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 11.5616899240 14706259
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 11.5617457977
MESH:D008113 Liver Neoplasms 1,3-butadiene 91.642208121
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 91.647678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 91.6416273603 11376686 14678523 10672840 18001218 10737359
MESH:D008113 Liver Neoplasms 2-nitrofluorene 91.6415890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 91.6415890375
MESH:D008113 Liver Neoplasms 9,10-Dimethyl-1,2-benzanthracene 91.649643874
MESH:D008113 Liver Neoplasms Aflatoxin B1 91.6418177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 91.6414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 91.6420195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 91.6419294768
MESH:D008113 Liver Neoplasms dicyclanil 91.6420118626
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 91.6411940454
MESH:D008113 Liver Neoplasms Diethylnitrosamine 91.6418648771 19090486 19690152 19256749 18977376 9163691 19294768 2862719 18644402 20434301 15175105 21167192 19426721 19255062 19254457 20583210 18754104 18978307 20101389 20118626 19499222 10737359 20137499 15885732 19812893 19073162 12112319 21071580 12771043 19642983 16942905 19833225 21278145 20501860 19638242 19850985 19427195 20405173 20452335 21047994 2422723 19551842 20492335 19996281
MESH:D008113 Liver Neoplasms Diethylstilbestrol 91.6416712894 15890375
MESH:D008113 Liver Neoplasms diethylthiourea 91.6411940454
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 91.6415890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 91.6415113037 17045692 16603448 18383874
MESH:D008113 Liver Neoplasms Methapyrilene 91.6415890375
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 91.6414757943 18709148
MESH:D008113 Liver Neoplasms Phenobarbital 91.648742319 19812893 19073162 21047994 15975961 19482888
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 91.6419690152 15890375 18648771 20101389
MESH:D008113 Liver Neoplasms pirinixic acid 91.6416377806 20007298 15890375
MESH:D008113 Liver Neoplasms propiconazole 91.6419028983
MESH:D008113 Liver Neoplasms Quercetin 91.6418980244
MESH:D008113 Liver Neoplasms resveratrol 91.6419073162 19812893 19321006 20405173
MESH:D008113 Liver Neoplasms Tamoxifen 91.6416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 91.6416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 77.786135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 77.781399818 6150874 534488
MESH:D008114 Liver Neoplasms, Experimental 9,10-Dimethyl-1,2-benzanthracene 77.781399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 77.788603461
MESH:D008114 Liver Neoplasms, Experimental Aflatoxins 77.7815583823
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 77.7820377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 77.7818544905
MESH:D008114 Liver Neoplasms, Experimental Benzene 77.7812562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 77.7815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 77.7819539802 17174075 19009564 18308698 18775883 18282651 16267830 21159647 18544905 3124819 18253720 19519916 18164116 17854601 19126423 17942915 18079962 19004024 16842330 18093689 2563599 9362446
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 77.7815603536 1848544 6150874
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 77.7816842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 77.781423854
MESH:D008114 Liver Neoplasms, Experimental kojic acid 77.7818544905
MESH:D008114 Liver Neoplasms, Experimental Organoselenium Compounds 77.7816170372
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 77.781399818 6150874 17172636 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental propiconazole 77.7817178689
MESH:D008114 Liver Neoplasms, Experimental Quercetin 77.7819519916
MESH:D008114 Liver Neoplasms, Experimental styrene oxide 77.7812562636
MESH:D008114 Liver Neoplasms, Experimental systhane 77.7817178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 77.7812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.6215213294
MESH:D008171 Lung Diseases Ascorbic Acid 5.5416863852
MESH:D008171 Lung Diseases Ozone 5.548266340 19066396
MESH:D017563 Lung Diseases, Interstitial Benzene 3.8814698565
MESH:D055370 Lung Injury Ozone 2.9720417186
MESH:D008175 Lung Neoplasms 1,3-butadiene 49.972208121 17372256 16860786
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 49.9711376686
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 49.9719931552 16061637 18508827 16401635 14755239 15172992 15893417 17139156 12438228 9255578 18813816
MESH:D008175 Lung Neoplasms 9,10-Dimethyl-1,2-benzanthracene 49.9711376689
MESH:D008175 Lung Neoplasms Aflatoxin B1 49.9714755239
MESH:D008175 Lung Neoplasms arsenic trioxide 49.9711798837 19825857
MESH:D008175 Lung Neoplasms arsenite 49.9716809336
MESH:D008175 Lung Neoplasms Asbestos 49.9712111688
MESH:D008175 Lung Neoplasms Ascorbic Acid 49.9716401635
MESH:D008175 Lung Neoplasms Benzene 49.9712562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 49.9720464547 20064080 18569708 18520028 18816296 20869020 20135361 17053015 6695378
MESH:D008175 Lung Neoplasms Cisplatin 49.976189445 17225452 11798837
MESH:D008175 Lung Neoplasms Diethylnitrosamine 49.9721163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 49.9716061637 11884234 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 49.9717418594 6189445
MESH:D008175 Lung Neoplasms Ethylene Oxide 49.9712562636 17325976
MESH:D008175 Lung Neoplasms Ethylnitrosourea 49.976695378 16019985 17703301 16271038
MESH:D008175 Lung Neoplasms Fluorouracil 49.9715246190
MESH:D008175 Lung Neoplasms Ozone 49.978597069 7614698
MESH:D008175 Lung Neoplasms Polycyclic Hydrocarbons, Aromatic 49.9710814675
MESH:D008175 Lung Neoplasms Quercetin 49.9716280456
MESH:D008175 Lung Neoplasms Styrene 49.9712562636
MESH:D008175 Lung Neoplasms Tamoxifen 49.9718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 49.9711884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 3.8815086387
MESH:D008180 Lupus Erythematosus, Systemic Carbamazepine 3.2216628512
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.2315166399
MESH:D008223 Lymphoma 1,3-butadiene 28.9111980663 9205081 2208121 17941976 18798262 9488045 8764131
MESH:D008223 Lymphoma 9,10-Dimethyl-1,2-benzanthracene 28.9111376689
MESH:D008223 Lymphoma Benzene 28.9117584886 17119257
MESH:D008223 Lymphoma Cyclophosphamide 28.9112854902
MESH:D008223 Lymphoma decitabine 28.9119470736
MESH:D008223 Lymphoma Diethylstilbestrol 28.9115700306
MESH:D008223 Lymphoma Doxorubicin 28.9116098063
MESH:D008223 Lymphoma Ethylnitrosourea 28.9115790496
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 7.6416675587
MESH:D016393 Lymphoma, B-Cell resveratrol 7.6417088997
MESH:D008228 Lymphoma, Non-Hodgkin 2,4-Dichlorophenoxyacetic Acid 14.4316132792
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 14.4311911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 14.4317654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 14.4314749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 8.7215621674
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 8.7215375218
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.5816002989
MESH:D015674 Mammary Neoplasms, Animal 1,3-butadiene 27.262208121
MESH:D015674 Mammary Neoplasms, Animal Benzene 27.2612562636
MESH:D015674 Mammary Neoplasms, Animal Ethylene Oxide 27.2612562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 27.2615688416
MESH:D015674 Mammary Neoplasms, Animal Styrene 27.2612562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 27.2619428831
MESH:D008325 Mammary Neoplasms, Experimental 1,3-butadiene 37.4911921183
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 37.4911921183
MESH:D008325 Mammary Neoplasms, Experimental 9,10-Dimethyl-1,2-benzanthracene 37.498985016 16082771 12844480 18840765 10697514 11807958 16153821 1500032
MESH:D008325 Mammary Neoplasms, Experimental Benzene 37.4911921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 37.4915458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 37.4916891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Ethylene Oxide 37.4911921183
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 37.4910767621 10838139 18041768
MESH:D008325 Mammary Neoplasms, Experimental Genistein 37.4914578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 37.4911606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 37.4919196723 14580682 19196722 11731420 16827153
MESH:D008325 Mammary Neoplasms, Experimental Zinc 37.4912773700
MESH:D020149 Manganese Poisoning Estradiol 9.5619453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.5619453300
MESH:D008545 Melanoma Carmustine 8.9212393984
MESH:D008545 Melanoma Cisplatin 8.9216432458 18332650 17761969 18176117 15577323 12883367 18505091 12393984 17023156 11135225 16809738 12374674 16248763
MESH:D008545 Melanoma decitabine 8.9217785578 16505122
MESH:D008545 Melanoma Doxorubicin 8.9216827129
MESH:D008545 Melanoma resveratrol 8.9217992120
MESH:D008545 Melanoma Tamoxifen 8.9212393984 19393235
MESH:D018328 Melanoma, Amelanotic Cisplatin 8.4815990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 8.4815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 7.8719513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 7.8716388313
MESH:D008569 Memory Disorders sevoflurane 3.8919212262
MESH:D008579 Meningioma Ethylnitrosourea 5.0517943659
MESH:D008607 Mental Retardation Carbamazepine 5.109014606
MESH:D008607 Mental Retardation Phenytoin 5.109212184
MESH:D008654 Mesothelioma Asbestos 7.6218310086 16564556 16919927 16319530 18709470
MESH:D008654 Mesothelioma Cisplatin 7.6217638057
MESH:D008654 Mesothelioma Doxorubicin 7.6217638057
MESH:D008659 Metabolic Diseases resveratrol 3.5417112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.8516801185
MESH:D008679 Metaplasia Ozone 4.1710496685
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.6615792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.0516381670
MESH:D009062 Mouth Neoplasms Fluorouracil 6.0516757204 18986760
MESH:D052016 Mucositis Doxorubicin 3.8817415656
MESH:D009101 Multiple Myeloma marker/mechanism 16949155
MESH:D009101 Multiple Myeloma arsenic trioxide 11.5115949261 14977855 19417148 19549372 11468182
MESH:D009101 Multiple Myeloma Benzene 11.5117119195
MESH:D009101 Multiple Myeloma decitabine 11.5118172295
MESH:D009101 Multiple Myeloma resveratrol 11.5117164350 17049120 14749477 16490592 17935668 16267019
MESH:D009134 Muscular Atrophy, Spinal resveratrol 3.9617962980
MESH:D009135 Muscular Diseases pirinixic acid 2.6216239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.7418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.4516105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 5.4519010910 18608210 19157545 16882708
MESH:D009203 Myocardial Infarction Doxorubicin 12.6019429709 15857846
MESH:D009203 Myocardial Infarction Genistein 12.6017141266
MESH:D009203 Myocardial Infarction pirinixic acid 12.6019151258
MESH:D009203 Myocardial Infarction Quercetin 12.6019595682
MESH:D009203 Myocardial Infarction resveratrol 12.6016317513 17188708 17125593 16525036 16456233 17015251
MESH:D017202 Myocardial Ischemia resveratrol 6.4717125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.4712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.2016810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 14.2017141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.2016411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 14.2019207477
MESH:D009205 Myocarditis resveratrol 3.8517322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 9.4617484760
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 9.4617484760
MESH:D009224 Myotonia Congenita Carbamazepine 9.4520399394
MESH:D009224 Myotonia Congenita Phenytoin 9.451896199
MESH:D009336 Necrosis 2,4-dinitrotoluene 23.8018551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 23.807678174 18551238
MESH:D009336 Necrosis 2-nitropropane 23.8012195237
MESH:D009336 Necrosis Trinitrotoluene 23.8018551238
MESH:D009336 Necrosis Warfarin 23.8014723717
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.0916624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 6.703581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 6.7018259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 6.7019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1219410462
MESH:D009369 Neoplasms 9,10-Dimethyl-1,2-benzanthracene 25.1911544531
MESH:D009369 Neoplasms Benzo(a)pyrene 25.1911141357
MESH:D009369 Neoplasms Cisplatin 25.1916773208
MESH:D009369 Neoplasms Cyclophosphamide 25.1918854779
MESH:D009369 Neoplasms decitabine 25.1919116145 17925555 19470736
MESH:D009369 Neoplasms Diethylstilbestrol 25.1915313581
MESH:D009369 Neoplasms fenvalerate 25.192895627
MESH:D009369 Neoplasms Fluorouracil 25.1918600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 25.1917405874
MESH:D009369 Neoplasms Quercetin 25.1915185748
MESH:D009374 Neoplasms, Experimental 1,3-butadiene 14.749205081 9488045 8764131
MESH:D009374 Neoplasms, Experimental erythritol anhydride 14.7410925838
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 14.7416707424
MESH:D009374 Neoplasms, Experimental resveratrol 14.748985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.0819196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic arsenite 7.1415738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.1417289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.5715464296
MESH:D009401 Nephrosis Doxorubicin 3.8716636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.5117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.6519348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.6515640375 16889571
MESH:D009421 Nervous System Malformations Carbamazepine 21.6216990009
MESH:D009421 Nervous System Malformations Diethylstilbestrol 21.6211399458
MESH:D009421 Nervous System Malformations Estradiol 21.6211399458 16427766
MESH:D009421 Nervous System Malformations Genistein 21.6216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 21.6214600291
MESH:D009436 Neural Tube Defects arsenic trioxide 8.4910525206
MESH:D009436 Neural Tube Defects Benzene 8.4915643154
MESH:D009436 Neural Tube Defects Phenytoin 8.499118846
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.5016651423 16003739 17160924
MESH:D009447 Neuroblastoma 1,3-butadiene 11.6515814359
MESH:D009447 Neuroblastoma Cisplatin 11.658761367
MESH:D009447 Neuroblastoma Cyclophosphamide 11.658761367 15176712 16115947
MESH:D009447 Neuroblastoma Doxorubicin 11.6515555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.5718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 9.5720387270
MESH:D019636 Neurodegenerative Diseases resveratrol 9.5717652729
MESH:D017599 Neuroectodermal Tumors Cisplatin 8.508761367
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 8.508761367 12837982
MESH:D020078 Neurogenic Inflammation Quercetin 7.8617929310
MESH:D020078 Neurogenic Inflammation resveratrol 7.8617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1820387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.7616436463
MESH:D009503 Neutropenia Cyclophosphamide 3.488291058
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 9.099802331
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 9.099802331
MESH:D009765 Obesity Ascorbic Acid 3.6117217161
MESH:D009765 Obesity pirinixic acid 3.6120558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 19.7716049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 19.7716049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 19.7714694615
MESH:D009784 Occupational Diseases Benzene 19.7715612468 15935809 15576619 15727169 17119257 16737584 17178637 15913788 17479406
MESH:D009784 Occupational Diseases Trinitrotoluene 19.7717852074 12819281 14694615
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.0517160924
MESH:D009845 Oligospermia Cyclophosphamide 3.8016517039
MESH:D010018 Osteomalacia Carbamazepine 15.0817016548
MESH:D010018 Osteomalacia Phenobarbital 15.0817016548
MESH:D010018 Osteomalacia Phenytoin 15.0817016548
MESH:D010024 Osteoporosis Genistein 2.6319401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 11.9816169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 11.9819495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 11.9817513867
MESH:D012516 Osteosarcoma Doxorubicin 3.3515930896
MESH:D010051 Ovarian Neoplasms 1,3-butadiene 26.732208121
MESH:D010051 Ovarian Neoplasms 9,10-Dimethyl-1,2-benzanthracene 26.7316891317
MESH:D010051 Ovarian Neoplasms arsenic trioxide 26.7312452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Benzene 26.7312562636
MESH:D010051 Ovarian Neoplasms Cisplatin 26.7319769630 17225452 6897625 15464296
MESH:D010051 Ovarian Neoplasms decitabine 26.7319259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 26.7319401270
MESH:D010051 Ovarian Neoplasms Genistein 26.7319005980
MESH:D010051 Ovarian Neoplasms Medroxyprogesterone Acetate 26.7317393432
MESH:D010051 Ovarian Neoplasms Quercetin 26.7319005980
MESH:D010146 Pain Acetaminophen 9.9816870215
MESH:D010146 Pain Carbamazepine 9.9815215642
MESH:D010146 Pain Cyclophosphamide 9.9812161096 18093676
MESH:D010146 Pain Phenytoin 9.9815215642
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 25.0012384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 25.0015580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 25.0019003803
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 25.0011332152
MESH:D010190 Pancreatic Neoplasms decitabine 25.0019294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 25.0016540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 25.0019003803 16929163 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 25.0016965848
MESH:D010190 Pancreatic Neoplasms Quercetin 25.0016965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.8311578682
MESH:D010212 Papilloma 9,10-Dimethyl-1,2-benzanthracene 4.4116517061 15173996 17234724
MESH:D010235 Paraganglioma arsenic trioxide 3.3119927285
MESH:D010243 Paralysis fenvalerate 5.098952708
MESH:D010267 Parapsoriasis Carbamazepine 4.8016538176
OMIM:167400 PAROXYSMAL EXTREME PAIN DISORDER Carbamazepine 5.0117145499 17679678
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3212520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.4415464296
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.4715687053
MESH:D010538 Peritonitis Ozone 3.2416369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.2217983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.2414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.7715687265 16977796
MESH:D010997 Pleural Neoplasms Cisplatin 10.8517638057
MESH:D010997 Pleural Neoplasms Doxorubicin 10.8517638057
MESH:D011014 Pneumonia Ozone 3.4818007984 18929643 18381685
MESH:D017689 Polydactyly Phenytoin 4.249212184
MESH:D011115 Polyneuropathies Ethylene Oxide 5.268472653
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 8.209918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.2018163543
MESH:D011230 Precancerous Conditions Cyclosporine 15.3812371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 15.382563599
MESH:D011230 Precancerous Conditions Phenobarbital 15.382563599
MESH:D011230 Precancerous Conditions Quercetin 15.3819056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.2121297632
MESH:D011225 Pre-Eclampsia marker/mechanism
MESH:D011225 Pre-Eclampsia Zinc 3.4317114810
MESH:D011248 Pregnancy Complications 2,4-Dichlorophenoxyacetic Acid 8.632087686
MESH:D011248 Pregnancy Complications Carbamazepine 8.639014606
MESH:D011297 Prenatal Exposure Delayed Effects marker/mechanism
MESH:D011297 Prenatal Exposure Delayed Effects Carbamazepine 26.269014606
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 26.2617184923
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 26.2617132714
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 26.2616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 26.2611118676 11399792 11222880 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 26.2618042343 18220299 19015723
MESH:D055728 Primary Myelofibrosis decitabine 3.8317616702
MESH:D011469 Prostatic Diseases vinclozolin 4.0218220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0520887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 17919073
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.5319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.5317292933
MESH:D011471 Prostatic Neoplasms Cadmium 4.5317075824
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 4.5317136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.5315846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 4.5316868541 15897917 15749863 18437689 16888761 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 4.5316740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 4.5318626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 4.5316925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Quercetin 4.5317292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 4.5317675339 16731767 17804756 17718901 17636462 15767336
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.5315067354
MESH:D011471 Prostatic Neoplasms Zinc 4.5316517595 16606632 12429649 16700911
MESH:D011472 Prostatitis vinclozolin 4.0218629315
MESH:D020151 Protein C Deficiency Warfarin 5.4318376272
MESH:D011537 Pruritus Ethinyl Estradiol 2.4115861022 16919318
MESH:D019310 Pseudolymphoma Carbamazepine 15.959591791 12752131
MESH:D019310 Pseudolymphoma Phenobarbital 15.9512752131
MESH:D019310 Pseudolymphoma Phenytoin 15.958603615 12752131 1419762
MESH:D011565 Psoriasis Cyclosporine 1.8116882103
MESH:D011655 Pulmonary Embolism Warfarin 5.4319300499
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.4014606601
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 2.8516636934
MESH:D012004 Rectal Neoplasms Fluorouracil 3.2115538739 18286688 18722050 16160472
MESH:D051437 Renal Insufficiency Cisplatin 7.4215464296
MESH:D051437 Renal Insufficiency Doxorubicin 7.4217922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.6516325855
MESH:D015427 Reperfusion Injury pirinixic acid 4.7319058328
MESH:D015427 Reperfusion Injury resveratrol 4.7316314181 16317513 17058453 15827377 17520802
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9618990726
MESH:D012162 Retinal Degeneration Zinc 3.4016584753
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 2.9616849425
MESH:D012208 Rhabdomyosarcoma decitabine 3.5519155313
MESH:D012509 Sarcoma Doxorubicin 3.1815675481 15625365 17203757 16767912 17710206 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 12.2516646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 12.2514601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 12.2514601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.8817846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.6116862918
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 3.9616636934
MESH:D012640 Seizures 2,4-dinitrotoluene 14.5118551238
MESH:D012640 Seizures 2,6-dinitrotoluene 14.5118551238
MESH:D012640 Seizures Carbamazepine 14.519844417 15946322 16876388 9046859 19414003 16180713 16938433
MESH:D012640 Seizures Phenobarbital 14.513137016 16876388 11442880 4039156
MESH:D012640 Seizures Phenytoin 14.5116876388 11044598 19919933 10029267 3691417 9844417 15946322 3137016
MESH:D012640 Seizures Trinitrotoluene 14.5118551238
MESH:D003294 Seizures, Febrile Phenobarbital 3.906407741
MESH:D012851 Sinus Thrombosis, Intracranial Warfarin 4.9712269725
MESH:D012871 Skin Diseases Ascorbic Acid 4.4218709164
MESH:D012871 Skin Diseases halofuginone 4.4211874485
MESH:D012878 Skin Neoplasms 9,10-Dimethyl-1,2-benzanthracene 12.2315173996 16517061 8985016 11376689
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.2310029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 12.2315692506
MESH:D012878 Skin Neoplasms resveratrol 12.2315837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.2316192470
MESH:D012893 Sleep Disorders Carbamazepine 4.2119414003
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.4115464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.6717203757 15625365 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 14.7816709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 14.7816709447
MESH:D013088 Spermatocele Tamoxifen 14.7816709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.6016517039
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.1319457130
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.3412587719
MESH:D013163 Splenomegaly Trinitrotoluene 4.3015817613
MESH:D013262 Stevens-Johnson Syndrome Carbamazepine 8.6019915237 19694795 16538176 18855540 15057820 16415921 20485159
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 8.6020235791
MESH:D013274 Stomach Neoplasms 1,3-butadiene 13.4311397402 2208121
MESH:D013274 Stomach Neoplasms arsenic trioxide 13.4317007042
MESH:D013274 Stomach Neoplasms Benzene 13.4312562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 13.4320155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 13.4317522103 18396642 15958060
MESH:D013274 Stomach Neoplasms decitabine 13.4319037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 13.4318456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 13.4316033868
MESH:D013274 Stomach Neoplasms Fluorouracil 13.4317522103 18396642 16424979 19015929 17498489 18567086 19084572 16951190 17172411 15786421
MESH:D013274 Stomach Neoplasms styrene oxide 13.4312562636
MESH:D013276 Stomach Ulcer Ascorbic Acid 3.1218726076
MESH:D020521 Stroke Ascorbic Acid 6.8916517955 16403987
MESH:D020521 Stroke Warfarin 6.8919300499
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.6616321402
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.1412837982
MESH:D013733 Testicular Diseases pyrazole 3.916499806
MESH:D013736 Testicular Neoplasms Cisplatin 3.7717225452 15464296
MESH:D013923 Thromboembolism Warfarin 5.2316960144 18698879
MESH:D019851 Thrombophilia Ethinyl Estradiol 8.1811994571
MESH:D019851 Thrombophilia Warfarin 8.1817493413
MESH:D013927 Thrombosis Ethinyl Estradiol 6.7815669648
MESH:D013927 Thrombosis Warfarin 6.7819300499 17672075 15720958 11518727 17245631 11307788
MESH:D013953 Thymus Neoplasms Benzene 9.1710850423
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 9.1715790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.9712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 18.5819014326
MESH:D013964 Thyroid Neoplasms decitabine 18.5817967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 18.587505956
MESH:D013964 Thyroid Neoplasms diethylthiourea 18.5811940454 1907225
MESH:D013964 Thyroid Neoplasms Doxorubicin 18.5816010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 18.581399818
MESH:D013978 Tibial Fractures Estradiol 3.7519048282
MESH:D014062 Tongue Neoplasms Fluorouracil 11.9616280240
MESH:D014062 Tongue Neoplasms resveratrol 11.9616227395
MESH:D014062 Tongue Neoplasms Zinc 11.9616543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.0615213294
MESH:D014202 Tremor fenvalerate 4.648952708
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 34.5016049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 34.5016049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 34.501399818 15289314 15867355
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 34.5020435036 12973940 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 34.5017053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 34.5012973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 34.5014692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 34.5017616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 34.5016712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 34.5017653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 34.5016720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 34.5017572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 8.9610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 8.9610091137
MESH:D014581 Urticaria Acetaminophen 2.1410982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 16.0316803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 16.0316175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 16.0316803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 16.0317473185
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.2414652134
MESH:D014594 Uterine Neoplasms Benzene 20.8912562636
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 20.8915809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 20.8914692618
MESH:D014594 Uterine Neoplasms Ethylene Oxide 20.8917325976 12562636
MESH:D014594 Uterine Neoplasms resveratrol 20.8917044934
MESH:D014604 Uveal Neoplasms decitabine 3.9817785578
MESH:D014605 Uveitis Cyclosporine 3.051336536
MESH:D014625 Vaginal Neoplasms Cisplatin 8.1215577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 8.1216002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6612125929
MESH:D014657 Vasculitis Warfarin 4.9720337814
MESH:D054556 Venous Thromboembolism Warfarin 5.4318776969
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 7.9615869587 14671159
MESH:D020246 Venous Thrombosis Warfarin 7.9614723717 15733061
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 7.3816364871 17334414 17638931 17678736
MESH:D018487 Ventricular Dysfunction, Left resveratrol 7.3817488730
MESH:D014839 Vomiting Cisplatin 3.7911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3215886252
MESH:D014985 Xerophthalmia Cyclosporine 3.5117120751
Pathway ID Pathway Name
KEGG:04976 Bile secretion
KEGG:00980 Metabolism of xenobiotics by cytochrome P450
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27829
    • No data
    Releated disease ID Related disease Name
    PA447178Pulmonary Disease, Chronic Obstructive
    PA446836Craniofacial Abnormalities
    PA443622Carcinoma, Non-Small-Cell Lung
    PA443223Congenital Abnormalities
    PA444065Epilepsy
    PA445376Polycystic Ovary Syndrome
    PA444818Lung Neoplasms
    Releated drug ID Related drug Name
    PA450947phenytoin
    PA449383docetaxel
    PA448785carbamazepine
    PA451846valproic acid
    PA449345dinoprostone
    PA449479epoprostenol
    PA164712740Epoxides
    PA451906warfarin
    PA452604xenobiotics
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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