AutismKB 2.0

Annotation Detail for EPHX2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EPHX2 ( CEH,SEH )
Gene Full Name: epoxide hydrolase 2, cytoplasmic
Band: 8p21.2-p21.1
Quick LinksEntrez ID:2053; OMIM: 132811; Uniprot ID:HYES_HUMAN; ENSEMBL ID: ENSG00000120915; HGNC ID: 3402
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00590Arachidonic acid metabolism
hsa01100Metabolic pathways
hsa04146Peroxisome
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1709Parkinson disease
1918Atherosclerosis
1934Cancer
1954Stroke
2091Hypertension
Desease Name
coronary artery calcification
atherosclerosis, coronary
CARDIOVASCULAR
stroke, ischemic
METABOLIC
diabetes, type 2
No data
Desease Name
Hypercholesterolemia, familial, due to LDLR defect, modifier of
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of EPHX2 mRNAdecreases expression 18648102
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of EPHX2 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of EPHX2 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of EPHX2 mRNAincreases expression 17530438
C015001 arsenite arsenite results in increased expression of EPHX2 mRNAincreases expression 18929588
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX2 mRNAaffects cotreatment|decreases expression 17639512
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of EPHX2 mRNAdecreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased activity of EPHX2 proteinincreases activity 19889059
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of EPHX2 mRNAincreases expression 19889059
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of EPHX2 proteinincreases expression 19889059
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of EPHX2 mRNAincreases expression 14729362
D002118 Calcium Calcium affects the expression of EPHX2 mRNAaffects expression 15913539
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of EPHX2 mRNAincreases expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of EPHX2 mRNAaffects expression 12734012
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EPHX2 mRNAdecreases expression 16039398
D003314 Corn Oil Corn Oil affects the expression of EPHX2 mRNAaffects expression 16360708
D016572 Cyclosporine Cyclosporine results in decreased expression of EPHX2 mRNAdecreases expression 20106945
D015084 2,4-Dichlorophenoxyacetic Acid 2,4-Dichlorophenoxyacetic Acid results in increased activity of EPHX2 proteinincreases activity 1755024
3032197
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C121718 dicyclanil dicyclanil results in increased expression of EPHX2 mRNAincreases expression 15664270
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX2 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX2 mRNAaffects cotreatment|increases expression 18544905
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of EPHX2 mRNAaffects cotreatment|increases expression 17347304
C017690 fenvalerate fenvalerate metabolite results in increased activity of EPHX2 proteinincreases activity 10630566
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of EPHX2 mRNAaffects cotreatment|increases expression 17347304
D005419 Flavonoids Flavonoids results in decreased expression of EPHX2 mRNAdecreases expression 18035473
C453899 GW 7647 GW 7647 results in decreased activity of EPHX2 proteindecreases activity 15798002
D006581 Hexachlorobenzene Hexachlorobenzene results in decreased expression of EPHX2 mRNAdecreases expression 15159207
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of EPHX2 mRNAincreases expression 14729362
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX2 mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX2 mRNAaffects cotreatment|increases expression 18544905
C008340 mecoprop mecoprop results in increased activity of EPHX2 proteinincreases activity 1755024
D008748 Methylcholanthrene Methylcholanthrene results in increased activity of EPHX2 proteinincreases activity 19889059
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of EPHX2 mRNAincreases expression 19889059
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of EPHX2 proteinincreases expression 19889059
D015741 Metribolone Metribolone results in increased expression of EPHX2 proteinincreases expression 17152098
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of EPHX2 mRNAincreases expression 18467677
17681415
C023036 perfluorooctanoic acid PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of EPHX2 mRNA]increases expression|increases reaction 18467677
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased activity of EPHX2 proteindecreases activity 10528994
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of EPHX2 mRNAincreases expression 16221955
D010656 Phenylephrine Phenylephrine results in decreased expression of EPHX2 mRNAdecreases expression 18158353
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of EPHX2 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of EPHX2 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of EPHX2 mRNAincreases expression 18467677
15375163
20059764
18301758
17426115
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of EPHX2 mRNA]increases expression|increases reaction 20059764
18467677
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX2 mRNAaffects cotreatment|decreases expression 17639512
D011794 Quercetin Quercetin results in decreased expression of EPHX2 mRNAdecreases expression 17103110
D011794 Quercetin Quercetin results in increased expression of EPHX2 mRNAincreases expression 18095365
C488333 Ro 65-7199 Ro 65-7199 affects the expression of EPHX2 mRNAaffects expression 14610520
C488334 Ro 66-0074 Ro 66-0074 affects the expression of EPHX2 mRNAaffects expression 14610520
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D012643 Selenium Selenium results in increased expression of EPHX2 mRNAincreases expression 19244175
D015085 2,4,5-Trichlorophenoxyacetic Acid 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of and results in increased activity of EPHX2 proteinincreases activity|increases expression 3032197
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of EPHX2 mRNAdecreases expression 16039398
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] results in decreased expression of EPHX2 mRNAaffects cotreatment|decreases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of EPHX2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of EPHX2 mRNAdecreases expression 16054899
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased expression of EPHX2 mRNAincreases expression 15289447
D014508 Urea Urea analog results in decreased activity of EPHX2 proteindecreases activity 15798002
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 7.0518926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.0514514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 9.0418287403
MESH:D000138 Acidosis Ethanol 9.0411192467
MESH:D055371 Acute Lung Injury pirinixic acid 2.7218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 3.9411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 3.9420464547 20127859
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.0915814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 13.863712494
MESH:D000236 Adenoma Benzo(a)pyrene 13.866695378
MESH:D000236 Adenoma Diethylnitrosamine 13.866695378 10737359
MESH:D000236 Adenoma Methylcholanthrene 13.8610545420 6695378
MESH:D018248 Adenoma, Liver Cell dicyclanil 21.3717162532
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 21.3717620307 18056438 19061943 16434500 19052882 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 21.3716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 21.3716835633
MESH:D000382 Agricultural Workers' Diseases 2,4-Dichlorophenoxyacetic Acid 4.7016132792
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8815451040 15451039
MESH:D000544 Alzheimer Disease rosiglitazone 2.7519621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5811748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.8517084956
MESH:D000853 Anophthalmos Ethanol 4.4015513904
MESH:D001008 Anxiety Disorders Ethanol 3.6611141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.6519183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.7417460149
MESH:D001169 Arthritis, Experimental Dexamethasone 3.2717659584
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 3.0719898480
MESH:D001260 Ataxia Telangiectasia Quercetin 4.5515336622
MESH:D050197 Atherosclerosis Methylcholanthrene 3.1911922910
MESH:D001327 Autoimmune Diseases Quercetin 3.9919761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.581440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.0516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.0519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.0512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4815746008
MESH:D001919 Bradycardia Phenylephrine 4.1115306635
MESH:D001943 Breast Neoplasms Ascorbic Acid 3.4416443354
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.4417474063 20146248
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.4417474063
MESH:D001943 Breast Neoplasms Hexachlorobenzene 3.4415061365 12709520
MESH:D001943 Breast Neoplasms Methylcholanthrene 3.4417474063
MESH:D001943 Breast Neoplasms Quercetin 3.4418628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.4420435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9311589617
MESH:D002056 Burns Ethanol 4.2316374292
MESH:D002105 Cadmium Poisoning Quercetin 5.1116962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.363786805 15721981 16192424 16227642 16050911 15700767 16011737 15673190 18705752 16124888 10355542 16097048
MESH:D002277 Carcinoma Methylcholanthrene 7.2010545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.2016835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 15.433581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 15.4312619106 21507988 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 15.4314691202 15553829 16217749 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.4318788625
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 15.4317162532
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 15.4320514400 19418558 16935385 18665156 3084413 17173139 19052882 19519916 17978847 20007298 20727157 18978308 18788625 11831363 16502159 20084675 16569478 20935162 18210153 17138121 16328049 20524982 18506893 16540662 19701751 16698587 16878318 19539802 18393292 16830150 17761372 19822196 20214788 10737359 20432363 18971187 20101231 17428255 19208518 20512989 19919837 18785209 18691550 16807293 18056438 19171122 18494052 3581430 10672840 16779866 16681979 19394651 17162532 19335982 17055752 21159647 19107877 16288022 19383236
MESH:D006528 Carcinoma, Hepatocellular Ethanol 15.4315763234 15289165 18788625
MESH:D006528 Carcinoma, Hepatocellular Quercetin 15.4312508355 19519916
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.2711212258
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4319014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.467296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7412490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.4320419170
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 4.4311212258
MESH:D006332 Cardiomegaly Ethanol 14.3119332462
MESH:D006332 Cardiomegaly Phenylephrine 14.3117124262 17287366 15728586 16170337 11754973 11179087
MESH:D006332 Cardiomegaly Quercetin 14.3119794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 14.3118670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.2216936243
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 13.577505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 13.5712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 13.5721159647 7505956 17174075 2727394
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 13.5716192471
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.1219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1216835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 11.529022650 19486331
MESH:D002779 Cholestasis Cyclosporine 11.5219486331
MESH:D002779 Cholestasis pirinixic acid 11.5219176532
MESH:D002971 Cleft Lip Ethanol 3.3515513904
MESH:D002972 Cleft Palate Ethanol 5.3015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3012621046 16354765 8697196 15340226 15668235
MESH:D003092 Colitis Selenium 3.3617936198
MESH:D003110 Colonic Neoplasms arsenite 5.4015037631
MESH:D003110 Colonic Neoplasms Dexamethasone 5.4015824018
MESH:D003110 Colonic Neoplasms Quercetin 5.4019440933 11134977 19056647 17191121 17148506 16640504 15741050
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.4920501625
MESH:D015179 Colorectal Neoplasms Quercetin 2.4918095365 18852136
MESH:D003139 Common Cold Ascorbic Acid 5.0417323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7014669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.9710525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 4.9717728286
MESH:D019465 Craniofacial Abnormalities Ethanol 4.9715451039 15451040 10194807 19302082 15513904 11198716 11873399
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9710048152 20055451 15322242
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7015213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 5.6814531868 11298694 2524372 8970840 8156756 11906362 18759878 12868966
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.6812438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2218249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.103621924 2952479
MESH:D003920 Diabetes Mellitus rosiglitazone 3.9417446233
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.3819496084
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 9.2616506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.2620387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 9.2612642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.2617107852
MESH:D003967 Diarrhea Dexamethasone 3.307237001
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 13.3511289319 18289764 18648102 1440618 8291058 16192314 7440962 18692083 9653073 9328219 9022650 6679447 6482804
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.3515968718 17522070 16177239 7440962 19085960 10915739 11566570 4309450 15998439 21278145 19336974 7179309 7120509 9327722 10092053 2869522 6884620 15027814 6623471 16227642 3732212 3786805
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.3519107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 13.3511566570
MESH:D056486 Drug-Induced Liver Injury Selenium 13.3515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.3520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4411462148
MESH:C538011 Eales disease Ascorbic Acid 5.049068938
MESH:D004485 Eczema Dexamethasone 4.0512438553
MESH:D004487 Edema Dexamethasone 17.6219703484
MESH:D004487 Edema perfluorooctanoic acid 17.6212083418 17259670
MESH:D004487 Edema pirinixic acid 17.6212083418
MESH:D004487 Edema rosiglitazone 17.6212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 17.6212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4618230668 16714409 15322242
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.6510568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6816302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 9.343581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 9.3412903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.3416530937
MESH:D004938 Esophageal Neoplasms Ethanol 9.3416704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6911564622
MESH:D005234 Fatty Liver arsenic trioxide 42.2815073043
MESH:D005234 Fatty Liver arsenite 42.2818296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 42.2815959796 19224547 12631006 16045604 12795759 16239168 61145 17595544
MESH:D005234 Fatty Liver Cyclosporine 42.2819224547
MESH:D005234 Fatty Liver Diethylnitrosamine 42.2821071580 20387270
MESH:D005234 Fatty Liver Ethanol 42.2816409862 19236843 18620774
MESH:D005234 Fatty Liver Fish Oils 42.2818620774
MESH:D005234 Fatty Liver pirinixic acid 42.2819236843 20131406
MESH:D005234 Fatty Liver rosiglitazone 42.2819196556
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2217920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8715513904 16946407 15451040 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0411858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.586705139
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.5114633661 10962813
MESH:D005355 Fibrosis arsenite 23.2818296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.2818705752
MESH:D005355 Fibrosis Cyclosporine 23.2812639820 12168785
MESH:D005355 Fibrosis Quercetin 23.2819474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.2820067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8516904648
MESH:D005756 Gastritis Ethanol 4.2615046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.798708960
MESH:D005909 Glioblastoma Quercetin 3.1119804834
MESH:D005910 Glioma Quercetin 2.8717643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.647505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1510696789
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 9.8316080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.8320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.8310048152 11294989
MESH:D006333 Heart Failure marker/mechanism 18443590
MESH:D006333 Heart Failure pirinixic acid 6.0420558911
MESH:D006333 Heart Failure Selenium 6.0417162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9511000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.876705139
MESH:D006505 Hepatitis Carbon Tetrachloride 7.8719110552 19900420
MESH:D006529 Hepatomegaly fenvalerate 17.3215602828
MESH:D006529 Hepatomegaly perfluorooctanoic acid 17.323609246
MESH:D006529 Hepatomegaly pirinixic acid 17.3219176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 17.3212621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 5.7116490937 16863852
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.717520565
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6116959395 15340226 18606429 16354765 8697196
MESH:D006930 Hyperalgesia Ethanol 11.3618783367
MESH:D006930 Hyperalgesia perfluorooctanoic acid 11.3612083418
MESH:D006930 Hyperalgesia rosiglitazone 11.3612083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1016899240
OMIM:143890 HYPERCHOLESTEROLEMIA, AUTOSOMAL DOMINANT marker/mechanism
MESH:D006943 Hyperglycemia pirinixic acid 8.0020558911
MESH:D006943 Hyperglycemia Quercetin 8.0011834736 18262572
MESH:D006949 Hyperlipidemias Fish Oils 4.3615752949
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5215034207
MESH:D006968 Hypersensitivity, Delayed Corn Oil 11.2311484837
MESH:D006968 Hypersensitivity, Delayed Fish Oils 11.2311484837
MESH:D006973 Hypertension Cyclosporine 14.4810903974
MESH:D006973 Hypertension Dexamethasone 14.4817042910
MESH:D006973 Hypertension Phenylephrine 14.488949925 12717712
MESH:D006973 Hypertension Quercetin 14.4818356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 14.4818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6715338365
MESH:D006984 Hypertrophy Phenylephrine 4.1718502941 12791704
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.0018306037
MESH:D007248 Infertility, Male 2,4-Dichlorophenoxyacetic Acid 4.3212948887
MESH:D007249 Inflammation Dexamethasone 20.638960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 20.6318785209
MESH:D007249 Inflammation Flavonoids 20.6317296493
MESH:D007249 Inflammation perfluorooctanoic acid 20.6312083418
MESH:D007249 Inflammation rosiglitazone 20.6312083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 20.6312878042 12200463
MESH:D007249 Inflammation Tobacco Smoke Pollution 20.6318590791
MESH:D007251 Influenza, Human Quercetin 9.6016624496
MESH:D007251 Influenza, Human Selenium 9.6016624496
MESH:D007333 Insulin Resistance pirinixic acid 6.5516306350
MESH:D007333 Insulin Resistance rosiglitazone 6.5516306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.588074119 9022650
MESH:D007569 Jaw Abnormalities Ethanol 8.8415513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8416580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.0018306037
MESH:D007627 Keloid Quercetin 4.5317086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0015604871
MESH:D007674 Kidney Diseases Cyclosporine 5.2818776723 10903974 8314463
MESH:D007674 Kidney Diseases Quercetin 5.2816962696
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 8.7516518626
MESH:D007676 Kidney Failure, Chronic Selenium 8.7516518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 6.126582329
MESH:D007680 Kidney Neoplasms Cyclosporine 6.1212371664
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.6116316344
MESH:D007859 Learning Disorders Ethanol 3.7915451040
MESH:D007938 Leukemia arsenic trioxide 5.7315070760
MESH:D007938 Leukemia Quercetin 5.7317468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.3819077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0617050201 19850784 16968895 20471514 16467208
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9319225113 12712474 12018890 17712046 16966277 16112521 15748426 16891316 16331271 11468182 11161223 15213294 12679006 17107899 15336539 17649720 16330433 19035177 17869043 16823087 19075265 9834237 15622746 19642359 17217047
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9416882451
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.808812269
MESH:D017880 Limb Deformities, Congenital Ethanol 3.5017676605
MESH:D008103 Liver Cirrhosis arsenite 13.7718296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 13.7717174718 11903743 16221502 16943688 17157831 11408273 17334410 21278145 16239168
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.7718522880 18407596 18665156 19638242 20032147
MESH:D008103 Liver Cirrhosis Ethanol 13.7715289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6618295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.9215034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.9115730626 14716496 17805973 15931870 12632514 18412020 17721639 12546737 15673190 18376398 18205269 16015684 16248980 18251166 16027843 12445418 15338365 16136751 10355542 16638106 18210741 18054572 18279442 18395914 17761835 12898905 13678700 15925388 17708605 15818738 15057751 17922224 18472332 18006644 17631135 14620537 18166357 12389079 15959796 17698563 18317297 17557913 15650968 17823541 18472094 12666154 15893842 17714472 17525996 15370692 17766677 14512876 17976157 17900296 16033810 15362042 14724832 18187930 18481824 12649538 20821823 18339082 18277467 18420326 12609069 18418968 12586293 14716833 15996030 17869086 16116963 12958196 15052691 16011737 14748882 18429990 17565644 12667390 17481882 15123356 18263696 15876570 18156304 18395095 17944888 17640975 12741479 16192424 18705752 11481614 12632512 16097048 12445421
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.9116718785
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 9.9118166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.9115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 9.9112741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 9.9117347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.9112878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.6517285989 15720792 16246199 15830285 16964402
MESH:D008107 Liver Diseases Diethylnitrosamine 3.6517034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.2317347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7415123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3216899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 30.5018177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 30.5014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 30.5021137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 30.5019294768
MESH:D008113 Liver Neoplasms dicyclanil 30.5020118626
MESH:D008113 Liver Neoplasms Diethylnitrosamine 30.5018644402 21047994 21278145 21167192 19499222 20434301 18754104 19255062 19426721 20492335 18977376 19996281 20452335 19090486 19812893 19073162 19638242 20583210 19294768 19833225 15885732 2862719 20501860 20405173 20118626 21071580 18648771 9163691 19254457 19690152 18978307 12112319 20101389 19850985 15175105 16942905 2422723 19551842 19256749 19427195 20137499 10737359 12771043 19642983
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 30.5018709148 14757943
MESH:D008113 Liver Neoplasms pirinixic acid 30.5016377806 20007298 15890375
MESH:D008113 Liver Neoplasms Quercetin 30.5018980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 30.5016984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 42.543712494 598648 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 42.548603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 42.5420377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 42.5418544905
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 42.5415583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 42.5418775883 16842330 16267830 17942915 19009564 18308698 18079962 9362446 19539802 18093689 18544905 18282651 21159647 19126423 19004024 18253720 17174075 3124819 17854601 19519916 2563599 18164116
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 42.541423854
MESH:D008114 Liver Neoplasms, Experimental kojic acid 42.5418544905
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 42.541399818 598648
MESH:D008114 Liver Neoplasms, Experimental Quercetin 42.5419519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 42.5412151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0215213294
MESH:D008171 Lung Diseases Ascorbic Acid 3.6616863852
MESH:D008175 Lung Neoplasms Aflatoxin B1 18.9914755239
MESH:D008175 Lung Neoplasms arsenic trioxide 18.9911798837 19825857
MESH:D008175 Lung Neoplasms arsenite 18.9916809336
MESH:D008175 Lung Neoplasms Ascorbic Acid 18.9916401635
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 18.9920869020 18569708 20064080 18816296 17053015 18520028 20135361 20464547 6695378
MESH:D008175 Lung Neoplasms Dexamethasone 18.9911195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 18.9920970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Methylcholanthrene 18.9915390079 20512841 20970405 9230183 16337739 6695378 16271038 7750092 11893704 1399818 21163286 17909032 10545420
MESH:D008175 Lung Neoplasms Quercetin 18.9916280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 18.9911884234 19555203
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 18.9911091918 16288123 3440675 12111688
MESH:D008228 Lymphoma, Non-Hodgkin 2,4-Dichlorophenoxyacetic Acid 4.8016132792
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 5.4016827153
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.4015318939
MESH:D008569 Memory Disorders Ethanol 3.7818411066 15451040
MESH:D008654 Mesothelioma Selenium 2.6115107826
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.0217261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3516801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.6916381670
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 7.6915006635
MESH:D009101 Multiple Myeloma arsenic trioxide 6.4111468182 15949261 19417148 14977855 19549372
MESH:D009101 Multiple Myeloma Dexamethasone 6.4115867202 16118317 15744524
MESH:D009135 Muscular Diseases pirinixic acid 3.0916239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.7116882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.719809623
MESH:D009203 Myocardial Infarction pirinixic acid 5.0819151258
MESH:D009203 Myocardial Infarction Quercetin 5.0819595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.3416411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.3419207477
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5516624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.083581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.083581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 10.0711141357
MESH:D009369 Neoplasms fenvalerate 10.072895627
MESH:D009369 Neoplasms pirinixic acid 10.0717405874
MESH:D009369 Neoplasms Quercetin 10.0715185748
MESH:D009389 Neovascularization, Pathologic arsenite 3.9815738583
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9219348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 2.8114600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.306679447
MESH:D009436 Neural Tube Defects arsenic trioxide 6.3010525206
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 2.9920387270
MESH:D020078 Neurogenic Inflammation Quercetin 3.9617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6820387270
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.539802331
MESH:D009765 Obesity Ascorbic Acid 4.3417217161
MESH:D009765 Obesity pirinixic acid 4.3420558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.054026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.583988306
MESH:D010024 Osteoporosis Calcium 3.5117882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.8219495926
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.5119769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Quercetin 4.5119005980
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 10.9615580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 10.9616540662
MESH:D010190 Pancreatic Neoplasms Ethanol 10.9612384795
MESH:D010190 Pancreatic Neoplasms Quercetin 10.9616965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 7.927296757
MESH:D010212 Papilloma Hydrogen Peroxide 7.9212065085
MESH:D010235 Paraganglioma arsenic trioxide 3.7619927285
MESH:D010243 Paralysis fenvalerate 5.578952708
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8112520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.036228378
MESH:D010954 Plasmacytoma Selenium 4.4515087411
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 9.749918132
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.7418163543
MESH:D011230 Precancerous Conditions Corn Oil 18.9814668109
MESH:D011230 Precancerous Conditions Cyclosporine 18.9812371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 18.982563599
MESH:D011230 Precancerous Conditions Quercetin 18.9819056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3021297632
MESH:D011248 Pregnancy Complications 2,4-Dichlorophenoxyacetic Acid 5.312087686
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 8.2417132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.2411399792 11896295 11222880 11118676
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.7419131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.7417292933
MESH:D011471 Prostatic Neoplasms Quercetin 2.7414715546 17292933
MESH:D011565 Psoriasis Cyclosporine 2.0716882103
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.8914606601
MESH:D015427 Reperfusion Injury pirinixic acid 2.1719058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.6218379247 11700416
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.2118410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4318990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.053692021
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.1816849425
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.5516646077
MESH:D012554 Schistosomiasis japonica Quercetin 5.1116862918
MESH:D012640 Seizures Ethanol 2.899754883
MESH:D012852 Sinusitis Phenylephrine 4.277327846
MESH:D012871 Skin Diseases Ascorbic Acid 3.0918709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 15.6419755658 10029692
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 15.6412065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 15.648532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 15.6416192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 15.6418590791
MESH:D013272 Stomach Diseases Dexamethasone 3.8915472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.3017007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.3020155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.3018456281
MESH:D013274 Stomach Neoplasms Ethanol 4.3018456281
MESH:D013276 Stomach Ulcer Ascorbic Acid 10.0418726076
MESH:D013276 Stomach Ulcer Dexamethasone 10.0415138204
MESH:D013276 Stomach Ulcer Ethanol 10.0417189318 16755016 9562338 11906479 9211565 17918041
MESH:D020521 Stroke Ascorbic Acid 3.9516517955 16403987
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.889754883
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 10.063712494 6582329 1399818 6587162 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.0619014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 10.067505956
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5315213294
MESH:D014202 Tremor fenvalerate 5.138952708
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 13.858074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 13.8512973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 13.8517053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 13.8516720314
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 13.8512846360
MESH:D014605 Uveitis Cyclosporine 10.301336536
MESH:D014605 Uveitis Dexamethasone 10.301336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1512125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8115886252
MESH:D014985 Xerophthalmia Cyclosporine 4.0017120751
Pathway ID Pathway Name
KEGG:00590 Arachidonic acid metabolism
KEGG:01100 Metabolic pathways
KEGG:04146 Peroxisome
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27830
    • No data
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    PA444818Lung Neoplasms
    PA447054Stroke
    Releated drug ID Related drug Name
    PA449383docetaxel
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB02029 - N-Cyclohexyl-N'-(4-Iodophenyl)Urea
    DB03677 - N-Cyclohexyl-N'-Decylurea
    DB04213 - N-Cyclohexyl-N'-(Propyl)Phenyl Urea
    DB08256 - N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE
    DB08257 - 4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID
    DB08258 - 6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID
    DB08259 - 7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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