Annotation Detail for DHRSX
Basic Information Top
| Gene Symbol: | DHRSX ( CXorf11,DHRS5X,DHRS5Y,DHRSXY,DHRSY,SDR46C1 ) |
|---|---|
| Gene Full Name: | dehydrogenase/reductase (SDR family) X-linked |
| Band: | Xp22.33 and Yp11.2 |
| Quick Links | Entrez ID:207063; OMIM: NA; Uniprot ID:DHRSX_HUMAN; ENSEMBL ID: ENSG00000169084; HGNC ID: 18399 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of DHRSX mRNA | decreases expression | 20064835 |
| D007657 | Ketone Bodies | Ketone Bodies results in increased expression of DHRSX mRNA | increases expression | 16807920 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 2.07 | 20127859 20464547 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.90 | 6695378 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 4.84 | 19183758 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 1.98 | 17474063 20146248 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.15 | 20419170 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 2.09 | 16530937 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 2.87 | 20471113 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 2.18 | 21137059 20195826 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 1.57 | 6695378 20464547 18569708 17053015 18520028 20135361 20064080 20869020 18816296 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.57 | 16381670 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.36 | 11141357 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.90 | 17292933 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 2.55 | 19755658 10029692 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 1.56 | 2093021 20155912 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.32 | 17053015 |
| No data |