AutismKB 2.0

Annotation Detail for ABCA3


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Basic Information Top
Gene Symbol:ABCA3 ( ABC-C,ABC3,EST111653,LBM180,MGC166979,MGC72201,SMDP3 )
Gene Full Name: ATP-binding cassette, sub-family A (ABC1), member 3
Band: 16p13.3
Quick LinksEntrez ID:21; OMIM: 601615; Uniprot ID:ABCA3_HUMAN; ENSEMBL ID: ENSG00000167972; HGNC ID: 33
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Desease IDDesease Name
H00217Pulmonary surfactant metabolism dysfunction
Inherited disorders of ion transport and metabolism
Genetic disorders
Desease IDDesease Name
1832Congenital abnormality
2051Leukemia
2192Lung disease
Desease Name
lung disease
No data
Desease Name
Surfactant metabolism dysfunction, pulmonary, 3
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ABCA3 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of ABCA3 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of ABCA3 mRNAincreases expression 20458559
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of ABCA3 mRNAdecreases expression 17484886
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ABCA3 mRNAincreases expression 17942915
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABCA3 mRNA]decreases reaction|increases expression 17942915
D004958 Estradiol Estradiol affects the expression of ABCA3 mRNAaffects expression 14699072
D007213 Indomethacin Indomethacin results in decreased expression of ABCA3 mRNAdecreases expression 18360721
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of ABCA3 mRNAdecreases expression 17681415
C017947 sodium arsenite sodium arsenite affects the expression of ABCA3 mRNAaffects expression 19590694
C025643 vinclozolin vinclozolin affects the expression of ABCA3 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 7.4011798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 7.4011473722
MESH:D000230 Adenocarcinoma Indomethacin 7.4016537180
MESH:D000236 Adenoma Diethylnitrosamine 7.2410737359 6695378
MESH:D000236 Adenoma Indomethacin 7.2411497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.1419052882 17162532 16434500 17620307 19061943 18056438
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.9615276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.1717306315 16712894
MESH:D016301 Alveolar Bone Loss Indomethacin 5.6417225004
MESH:D000544 Alzheimer Disease Indomethacin 2.7317627676 15579461
MESH:D000799 Angioedema Acetaminophen 4.1110982225
MESH:D001008 Anxiety Disorders vinclozolin 3.7819015723
MESH:D001014 Aortic Aneurysm Indomethacin 5.0510231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 5.0910388637
MESH:D018771 Arthralgia Indomethacin 5.432160914
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8511248219
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001477 Bartter Syndrome Indomethacin 5.2010684365
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.8416206674
MESH:D001929 Brain Edema Indomethacin 5.2911481608
MESH:D002545 Brain Ischemia Indomethacin 4.6512524144
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9617474063
MESH:D001943 Breast Neoplasms Estradiol 1.9619861407 16675129 17018787 17289903 14630087 12948864 17261762 18497071
MESH:D001943 Breast Neoplasms Indomethacin 1.9617401462
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.5111589617
MESH:D002056 Burns Indomethacin 4.9210459503
MESH:D002100 Cachexia Indomethacin 5.2415141370 16537180 15625704 11239499
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.7016111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.9915721981 16124888 3786805 16097048 15700767 16011737 16227642 18705752 15673190 10355542 16050911 16192424
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 17.4116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 17.413084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 17.4115553829 16217749 15073043 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 17.4118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 17.4119539802 16779866 17978847 20524982 16328049 17761372 17055752 21159647 19171122 18393292 17138121 19519916 20514400 20512989 16288022 20007298 17173139 3084413 16502159 20935162 16878318 18785209 10672840 11831363 18788625 18971187 19701751 17428255 18506893 18665156 20727157 19418558 20432363 19394651 18691550 20084675 18494052 19052882 20214788 18210153 17162532 3581430 16569478 19822196 18056438 19335982 19919837 16807293 16830150 10737359 20101231 19107877 16540662 18978308 19383236 16935385 16681979 16698587 19208518
MESH:D006528 Carcinoma, Hepatocellular Estradiol 17.4116924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 17.4116391822
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 17.4117306315 16507464 15276417
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.9611053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.5911352223 18791128 14736730
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.1419014326
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.4417341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.2812490120
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 5.0412636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 5.0418572023
MESH:D002386 Cataract Acetaminophen 2.6710977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 17.016135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.017505956 17174075 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 17.0118566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.0120056578 19524636
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.8419052882
MESH:D002764 Cholecystitis Indomethacin 5.4311181007
MESH:D003110 Colonic Neoplasms Indomethacin 2.6115786552 15637740 11260862 15936596 15625704 15963497
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.7120501625
MESH:D015179 Colorectal Neoplasms Indomethacin 2.7112606626 17054584 18059344 11197048
MESH:D023903 Coronary Restenosis arsenic trioxide 4.3812609071
MESH:D018352 Coronavirus Infections Indomethacin 5.9817302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003456 Cryptorchidism vinclozolin 4.5414966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.2318551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.2815213294
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2220387270
MESH:D003928 Diabetic Nephropathies Estradiol 3.5619279558
MESH:D003967 Diarrhea Indomethacin 3.997907874 7237001
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.3521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.3519164858 11287661 12594235 14725611 11743745 10915739 19420014 12705907 11739529 17906064 18713872 12153990 12540782 10663392 19923254 16781746 2444490 19739265 11529661 14986274 15619225 16177239 14550746 16081117 16227642 16393943 18071297 15968718 19416960 16109766 19370779 12392966 16485898 19085960 11834606 10774834 11461765 17522070 11421492 12958197 17562736
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 9.3511566570 10915739 15027814 7440962 7179309 21278145 3732212 2869522 3786805 9327722 10092053 19085960 6884620 16177239 19336974 15998439 7120509 17522070 15968718 16227642 4309450 6623471
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 9.3519107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.3619426721
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.3918043480 17190690 18446180 16133044 16326151 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 4.3317151854 17202747 16699067 11595431 17351913 11991626 11595415 10671773 17045617 11535926 17329845
MESH:D004487 Edema Indomethacin 7.938985016 19703484 7990266 7907874 10653021 16100529 8273558
MESH:D004487 Edema perfluorooctanoic acid 7.9317259670 12083418
MESH:D016889 Endometrial Neoplasms Estradiol 3.0919148513 11473722 18566989
MESH:D004715 Endometriosis Indomethacin 4.3115652904
MESH:D019446 Endotoxemia Indomethacin 4.7418509659
MESH:D004751 Enteritis Indomethacin 5.0110567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.2017980183
MESH:D004802 Eosinophilia Indomethacin 4.2711298111
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.3816302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.8612903497
MESH:D004938 Esophageal Neoplasms Indomethacin 4.8611005569
MESH:D005234 Fatty Liver arsenic trioxide 14.1915073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 14.1917595544 15959796 16239168 12631006 61145 16045604 19224547 12795759
MESH:D005234 Fatty Liver Diethylnitrosamine 14.1921071580 20387270
MESH:D005334 Fever Indomethacin 4.2817627676 11852909 10431976
MESH:D005354 Fibrosarcoma Indomethacin 5.1310962813
MESH:D005355 Fibrosis Carbon Tetrachloride 9.7418705752
MESH:D005355 Fibrosis Indomethacin 9.7417994277
MESH:D005499 Folliculitis Indomethacin 5.4311298111
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.4616904648
MESH:D005756 Gastritis Acetaminophen 12.0516983495
MESH:D005756 Gastritis Indomethacin 12.0515046732
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.1716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.5716417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.9216452187
MESH:D005909 Glioblastoma Indomethacin 3.6712870263
MESH:D005910 Glioma Indomethacin 3.2818371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.4211849393
MESH:D006073 Gout Indomethacin 5.5911248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.8515482327
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.7415633222
MESH:D006505 Hepatitis Carbon Tetrachloride 3.7919900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.8815135802
MESH:D006529 Hepatomegaly perfluorooctanoic acid 4.313609246
MESH:D006558 Herpes Genitalis Estradiol 5.3015709030
MESH:D006689 Hodgkin Disease sodium arsenite 3.3012676792
MESH:D019584 Hot Flashes Estradiol 4.0217088409
MESH:D006930 Hyperalgesia Acetaminophen 13.9816870215
MESH:D006930 Hyperalgesia Indomethacin 13.9812727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 13.9812083418
MESH:D034321 Hyperamylasemia Indomethacin 5.9817883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.7716899240
MESH:D006940 Hyperemia Indomethacin 5.2412524144
MESH:D006949 Hyperlipidemias Indomethacin 4.3517546600
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.3015338365
MESH:D007077 Ileal Diseases Indomethacin 5.2918306037 10574470
MESH:D007079 Ileitis Indomethacin 5.5910647630 16133968 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.6416133044
MESH:D007248 Infertility, Male sodium arsenite 7.2215346721 12646999
MESH:D007248 Infertility, Male vinclozolin 7.2216467254
MESH:D007249 Inflammation Diethylnitrosamine 9.0018785209
MESH:D007249 Inflammation Indomethacin 9.003291741 12568917 7812673
MESH:D007249 Inflammation perfluorooctanoic acid 9.0012083418
MESH:D007333 Insulin Resistance Estradiol 3.0716393666 16627594
MESH:D007410 Intestinal Diseases Indomethacin 4.5411713966 17994277 10210152 18236018 15610444 11855677 15831440 11686837 17329856
MESH:D019586 Intracranial Hypertension Indomethacin 5.6415241188
MESH:D007579 Jejunal Diseases Indomethacin 5.2916133968 18306037 10574470
MESH:D007674 Kidney Diseases Acetaminophen 15.2415629191 12587719
MESH:D007674 Kidney Diseases Estradiol 15.2415618244
MESH:D007674 Kidney Diseases Indomethacin 15.2417190690
MESH:D007674 Kidney Diseases sodium arsenite 15.2420008137
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.8516705839
MESH:D007680 Kidney Neoplasms Estradiol 7.8515610895
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 4.0512228301 10320625 11703811
MESH:D007938 Leukemia arsenic trioxide 2.9115070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.9717077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.5416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 8.9814633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 8.9810785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.9319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.1817050201 16467208 20471514 16968895 19850784
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.1818360721
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.3217869043 16330433 17217047 15748426 19225113 19035177 12018890 16112521 16966277 17107899 12679006 19642359 11161223 15336539 16823087 16331271 17649720 9834237 16891316 12712474 15622746 17712046 15213294 11468182 19075265
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.5516882451
MESH:D007964 Leukocytosis Indomethacin 5.6416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.9817980183
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 13.748812269
MESH:D007984 Leydig Cell Tumor vinclozolin 13.7416417039
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.9811479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.9016239168 16943688 21278145 17157831 11408273 11903743 17334410 17174718 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.9020032147 18407596 19638242 18522880 18665156
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.6816136751 16097048 14748882 17823541 17481882 15057751 18472332 18429990 17869086 14716496 17557913 17698563 15818738 17565644 12649538 12389079 18472094 18054572 18395914 15925388 15673190 18263696 18277467 15650968 17714472 12445418 12546737 17525996 15730626 15370692 15931870 20821823 18412020 17976157 18251166 18156304 18376398 15876570 12898905 16015684 16638106 15959796 17922224 18418968 12958196 12445421 18339082 14512876 17721639 17944888 12586293 15052691 16192424 14724832 15123356 18420326 12632514 18317297 18279442 16011737 17631135 17900296 18187930 18481824 12632512 17640975 17766677 18395095 17761835 12609069 13678700 18705752 15338365 16116963 12741479 12667390 15362042 16033810 16248980 18006644 15996030 18166357 18210741 15893842 18205269 12666154 10355542 11481614 16027843 14716833 17805973 14620537 17708605
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.6814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 3.6818194892
MESH:D008107 Liver Diseases Acetaminophen 6.7016611625 12969438 16610002 19014921 19460945 19784758 11587558 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.7017285989 15830285 16246199 15720792 16964402
MESH:D008107 Liver Diseases Diethylnitrosamine 6.7017034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.3815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.9517185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.9516899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 18.777678174
MESH:D008113 Liver Neoplasms arsenic trioxide 18.7714682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 18.7719294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 18.7721167192 12112319 19642983 19690152 19254457 12771043 20501860 20137499 19996281 19294768 20583210 19638242 20118626 19499222 15175105 21278145 18648771 19426721 18977376 19551842 2422723 19427195 20101389 19812893 18978307 19850985 2862719 20405173 15885732 21047994 19255062 20492335 21071580 19090486 19073162 9163691 18644402 20434301 10737359 19256749 16942905 19833225 18754104 20452335
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 18.7718709148 14757943
MESH:D008113 Liver Neoplasms sodium arsenite 18.7715276417 16712894
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 14.992876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 14.9920377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.9912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 14.9919539802 17854601 16267830 18544905 19009564 18164116 16842330 18775883 19519916 18253720 9362446 18079962 21159647 19126423 18308698 18093689 17174075 2563599 18282651 17942915 19004024 3124819
MESH:D008133 Long QT Syndrome arsenic trioxide 3.4815213294
MESH:D008171 Lung Diseases sodium arsenite 3.2819095001
MESH:D008175 Lung Neoplasms arsenic trioxide 5.0411798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 5.0420970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms Indomethacin 5.0416537180 11497255 11053908
MESH:D008175 Lung Neoplasms sodium arsenite 5.0417077188 16712894 17306315 19931552 15276417
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.6616891317 17203775 11807958 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.7519453300
MESH:D008545 Melanoma sodium arsenite 2.0519082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7819513568
MESH:D008881 Migraine Disorders Indomethacin 3.7911903285
MESH:D009062 Mouth Neoplasms Indomethacin 4.1212636206
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2211468182 14977855 15949261 19417148 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.9418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2316105982 16882451
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.4116810080
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.107678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.1616624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 6.163581430 9029167
MESH:D009362 Neoplasm Metastasis Indomethacin 6.1611239499 16537180 11053908
MESH:D009369 Neoplasms sodium arsenite 2.5711559025
MESH:D009374 Neoplasms, Experimental Indomethacin 10.0115625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 10.0120056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.9717289903
MESH:D009421 Nervous System Malformations Estradiol 3.8516427766 11399458
MESH:D009436 Neural Tube Defects arsenic trioxide 7.6910525206
MESH:D009436 Neural Tube Defects sodium arsenite 7.6912854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 14.9318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 14.9320387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 14.9312349958
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.3820387270
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 5.179802331
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.436374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.5916049721
MESH:D010003 Osteoarthritis Indomethacin 3.767009135
MESH:D010051 Ovarian Neoplasms arsenic trioxide 8.1612452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 8.1619401270
MESH:D010051 Ovarian Neoplasms sodium arsenite 8.1617306315 15276417
MESH:D010146 Pain Acetaminophen 7.2716870215
MESH:D010146 Pain Indomethacin 7.2717627676 17440234 13679232 3291741
MESH:D010149 Pain, Postoperative Indomethacin 4.9412538197 18702446
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.4515580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.4516540662
MESH:D010195 Pancreatitis Indomethacin 4.1015028970 17883296
MESH:D010235 Paraganglioma arsenic trioxide 4.3519927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.9816537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.2812349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.9811903285
MESH:D010437 Peptic Ulcer Indomethacin 5.3911148446
MESH:D010518 Periodontitis Indomethacin 5.1817225004
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.702563599
MESH:D047928 Premature Birth Indomethacin 5.3417000239
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 10.7417132714
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 10.7418220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.1718220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.0620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5319131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.5316740699
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.5316039940
MESH:D011472 Prostatitis vinclozolin 5.1718629315
MESH:D011507 Proteinuria Indomethacin 4.3511849393
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.1616646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6418551238
MESH:D012878 Skin Neoplasms sodium arsenite 2.7718572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 3.9312854658
MESH:D013272 Stomach Diseases Indomethacin 4.6518545984 10486359 16280098 17160473 17207306 10215738 15472012 10192188 17638125 16113693 15038085 18209964 16184426
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.5217007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.5218456281
MESH:D013274 Stomach Neoplasms Indomethacin 3.5215609394
MESH:D013276 Stomach Ulcer Indomethacin 3.7517895592 11729361 17977527 12077510 16150113 16755016 10750652 18237397 1323529 16252198 17627676 12467913 10423059 18299717 18543354 11595415 10878458 12500499 17135157 11523592 16631530 18087811 16169175 12498302 18726076 15138204 12787963 11145282 11595431 14567935 17918041 16934674 17657623 18431645 11906479 16397915 18181030 15104355 18209962 15255614 17654042 18193104
OMIM:610921 SURFACTANT METABOLISM DYSFUNCTION, PULMONARY, 3 marker/mechanism
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.8319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.837505956
MESH:D013964 Thyroid Neoplasms Indomethacin 12.8311352223 14736730 18791128
MESH:D013978 Tibial Fractures Estradiol 4.9519048282
MESH:D016171 Torsades de Pointes arsenic trioxide 4.2015213294
MESH:D014456 Ulcer Indomethacin 5.1310574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.6916049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.6911780464 12845720 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.6916452187 16712894 17306315 11723127
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.5610091137
MESH:D014581 Urticaria Acetaminophen 3.1610982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.9311813266
MESH:D014652 Vascular Diseases sodium arsenite 4.6617056641
MESH:D014839 Vomiting Indomethacin 5.0111897121
Pathway ID Pathway Name
KEGG:02010 ABC transporters
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24378
    • Releated gene ID Related gene Name
    PA24378ABCA3
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top
    No data
    No data
    Drugbank ID Action Drug Name Description
    DB00619 substrate Imatinib Antineoplastic Agents;Protein Kinase Inhibitors
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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