AutismKB 2.0

Annotation Detail for ETV4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ETV4 ( E1A-F,E1AF,PEA3,PEAS3 )
Gene Full Name: ets variant 4
Band: 17q21.31
Quick LinksEntrez ID:2118; OMIM: 600711; Uniprot ID:ETV4_HUMAN; ENSEMBL ID: ENSG00000175832; HGNC ID: 3493
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200061LKB1 signaling events
No data
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Related Diseases/Disorders Top
Desease IDDesease Name
Cancers
H00035Ewing's sarcoma
Cancers of soft tissues and bone
Desease IDDesease Name
1934Cancer
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ETV4 mRNAaffects expression 17562736
D000728 Androgens Androgens affects the expression of ETV4 mRNAaffects expression 9444656
C006632 arsenic trioxide arsenic trioxide results in decreased expression of ETV4 mRNAdecreases expression 20458559
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ETV4 mRNAdecreases expression 20106945
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of ETV4 mRNAincreases expression 15003993
D002945 Cisplatin Cisplatin results in increased expression of ETV4 mRNAincreases expression 16061661
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ETV4 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ETV4 mRNA]decreases reaction|increases expression 17854601
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ETV4 mRNAaffects expression 17555576
D009151 Mustard Gas Mustard Gas results in increased expression of ETV4 mRNAincreases expression 15674843
C047088 phenylamil phenylamil results in increased expression of ETV4 mRNAincreases expression 20519739
D013629 Tamoxifen Tamoxifen affects the expression of ETV4 mRNAaffects expression 17555576
D014212 Tretinoin Tretinoin results in decreased expression of ETV4 mRNAdecreases expression 16604517
D002762 Cholecalciferol Cholecalciferol results in decreased expression of ETV4 mRNAdecreases expression 16508948
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6814745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0817505938
MESH:D058186 Acute Kidney Injury Cisplatin 4.0417670903 12690470 15814532
MESH:D000230 Adenocarcinoma arsenic trioxide 10.3511798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.3520464547 20127859
MESH:D000230 Adenocarcinoma Cisplatin 10.3517638652 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.3514692618
MESH:D000236 Adenoma Benzo(a)pyrene 6.786695378
MESH:D000236 Adenoma Diethylnitrosamine 6.786695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.0219052882 17162532 19061943 16434500 17620307 18056438
MESH:D000505 Alopecia Tretinoin 3.6815955085
MESH:D000544 Alzheimer Disease Androgens 3.6317917157 17182789
MESH:D000799 Angioedema Acetaminophen 3.9810982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1819183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.3715885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.3716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2816292516
MESH:D001249 Asthma Mustard Gas 5.0610378619
MESH:D001249 Asthma Tretinoin 5.0616456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001327 Autoimmune Diseases Cholecalciferol 5.1316142846
MESH:D001471 Barrett Esophagus Tretinoin 4.5016935849
MESH:D001768 Blister Mustard Gas 5.2819167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.4416206674
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.4416197459 16206674
MESH:D019046 Bone Marrow Neoplasms Cisplatin 5.0214601052
MESH:D001943 Breast Neoplasms Androgens 3.0117018787
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.0120146248 17474063
MESH:D001943 Breast Neoplasms Cisplatin 3.0118382427 19526202
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.0117474063
MESH:D001943 Breast Neoplasms Tamoxifen 3.0115668708 20544844 16873071 19011961 19084267 18351453 19410462 19189212 21138602 17893378 19103187 18815881 19289846 18855134 20859285 20135344 17242785 15565566 18821012 19115204 19059307 19221464 18629630 19189210 19244106 11161223 17049068 19142967 20065188 16202921 18984771 17440819 20390343 21152245 16273361 19155303 18997820 17261762 19487384 20005174 18425577 19288272 19200415 19066611 16818667
MESH:D001943 Breast Neoplasms Tretinoin 3.0116443354 16873071 16166294
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.2815286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.1117687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.4211589617
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.6119066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2916168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.563084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.5616217749 15073043 14691202 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 11.5617982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.5617978847 19519916 20727157 17162532 3084413 20101231 16935385 20935162 20514400 16830150 17761372 17428255 18506893 16540662 17055752 18494052 19701751 20512989 17173139 20524982 19171122 18978308 10672840 16807293 19822196 18785209 21159647 19383236 18393292 19107877 17138121 20007298 11831363 3581430 16328049 19394651 16502159 19335982 18210153 20084675 16569478 16698587 16288022 18971187 19539802 16878318 19052882 19919837 19208518 20432363 20214788 16681979 16779866 18056438 18788625 18665156 19418558 18691550 10737359
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.5616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.561917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 3.0616685392 12023789
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.0119014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1912490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.7020419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 7.7017066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.7016096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6917572228
MESH:D002386 Cataract Acetaminophen 7.3810977129
MESH:D002386 Cataract Tretinoin 7.3817460283
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 2.912727394 21159647 7505956 17174075
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7116129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.7619052882
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9316105132 17110522 16919318 15861022 17681005 11677210 17333356
MESH:D002822 Choriocarcinoma Tretinoin 5.2916461808
MESH:D002972 Cleft Palate Tretinoin 2.709407595
MESH:D003092 Colitis Tretinoin 3.8117035595
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6820501625
MESH:D015179 Colorectal Neoplasms Cisplatin 2.6815273666
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.7010525206
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.7014991402 10589399 9664655 16925845 9224671 17551590 9211117 9125849 9142499 8800419
MESH:D016638 Critical Illness Androgens 6.1816670151
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1815213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4719031437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2120387270
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5519279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.8210663392 11421492 12392966 19085960 11743745 15968718 12594235 16177239 16485898 17906064 11529661 12958197 14986274 11834606 14550746 17522070 19370779 18071297 11739529 10915739 18713872 11287661 17562736 16109766 19420014 12705907 12540782 16081117 16227642 19416960 19923254 16781746 12153990 14725611 19164858 19739265 16393943 11461765 2444490 10774834 15619225
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.8219107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2319426721
MESH:D004362 Drug Toxicity Cisplatin 3.9112231392 12649298 15033597 19839026
MESH:D004487 Edema Mustard Gas 3.399260866 11402378 11428647 11428631
MESH:D004489 Edema, Cardiac Tretinoin 4.6018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.2612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.2619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.6116202921 19155303 20544844 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 7.6116569247
MESH:D004890 Erythema Mustard Gas 5.289357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2516302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.4212903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.4216530937
MESH:D004938 Esophageal Neoplasms Cisplatin 7.4216785472 15173087 17638652 15464296 16481741
MESH:D005124 Eye Abnormalities Tretinoin 3.649664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 19.4815073043
MESH:D005234 Fatty Liver Diethylnitrosamine 19.4821071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.4815345470
MESH:D005234 Fatty Liver Tamoxifen 19.4814986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2816709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.3019069698
MESH:D005355 Fibrosis Tretinoin 3.6217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3616904648
MESH:D005756 Gastritis Acetaminophen 3.8116983495
MESH:D005909 Glioblastoma Tretinoin 3.0517312396
MESH:D006258 Head and Neck Neoplasms Cisplatin 8.0915102660 15464296
MESH:D006258 Head and Neck Neoplasms Tretinoin 8.0916096774
MESH:D034381 Hearing Loss Cisplatin 4.3719898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2916084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.4915464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.7920471113
MESH:D006330 Heart Defects, Congenital Tretinoin 6.7914991402 9664655
MESH:D006628 Hirsutism Androgens 6.2117019078 16914592
MESH:D006689 Hodgkin Disease Cisplatin 3.6616170182 16200630
MESH:D006930 Hyperalgesia Acetaminophen 7.8416870215
MESH:D006930 Hyperalgesia Tretinoin 7.8416870215
MESH:D017588 Hyperandrogenism Androgens 5.8717019078
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6716778211
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9116569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5417937319
MESH:D007249 Inflammation Diethylnitrosamine 8.6318785209
MESH:D007249 Inflammation Mustard Gas 8.6317524151 11402378 9357497 11428631 16001271 9260866 11428647 11428620 8975870
MESH:D007249 Inflammation Tamoxifen 8.6319457130
MESH:D007410 Intestinal Diseases Tretinoin 3.8717994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.9817551590 15992940
MESH:D007673 Kidney Cortex Necrosis Cisplatin 5.2715464296
MESH:D007674 Kidney Diseases Acetaminophen 6.2712587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 6.2712231392 18289764 12649298 15190930 19839026
MESH:D007680 Kidney Neoplasms Tamoxifen 3.1118625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.9311231351
MESH:D007938 Leukemia arsenic trioxide 6.4715070760
MESH:D007938 Leukemia Tretinoin 6.4717143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8817077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.4216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.7519077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.7516932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9320471514 16467208 19850784 16968895 17050201
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9319850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.8115748426 19035177 11161223 11468182 16331271 16112521 19225113 17107899 16330433 16823087 12679006 12712474 15336539 17649720 16966277 9834237 12018890 17712046 17217047 19075265 19642359 15213294 17869043 15622746 16891316
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.8116331271 19075265 15748426 16891316 17506722 17361223 16935935 16823087 19225113 19642359 12679006 19035177 19029980 9834237 17217047 17649720 17301526 17712046 16140955 16788101 16766008 17107899 17368321 17339181 17294898
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.4516882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.369224671
MESH:D008064 Lipidoses Tamoxifen 3.2117567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8718665156 18407596 18522880 19638242 20032147
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5118564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.5118397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 3.9719784758 16611625 19014921 12969438 19460945 16610002 12587719 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9717034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3116871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 10.9514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 10.9521137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 10.9520501860 20405173 2422723 9163691 19090486 20583210 20118626 19256749 18978307 19255062 21071580 19833225 19551842 19996281 19642983 19427195 2862719 21167192 15175105 21047994 19638242 20434301 19812893 15885732 18754104 19850985 19499222 10737359 19690152 20492335 20452335 16942905 12112319 20137499 18977376 21278145 12771043 19294768 20101389 18648771 19254457 19426721 19073162 18644402
MESH:D008113 Liver Neoplasms Tamoxifen 10.9516684651
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.1620377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.1618164116 18544905 18282651 18775883 18093689 18079962 18253720 19009564 19519916 17174075 18308698 16267830 16842330 9362446 17854601 19539802 3124819 2563599 19126423 19004024 17942915 21159647
MESH:D008133 Long QT Syndrome arsenic trioxide 3.4115213294
MESH:D008171 Lung Diseases Mustard Gas 3.5018161513 18702808
MESH:D008175 Lung Neoplasms arsenic trioxide 8.6911798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.6918816296 20464547 20869020 18569708 20135361 20064080 6695378 17053015 18520028
MESH:D008175 Lung Neoplasms Cisplatin 8.6917225452 11798837 6189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.6921163286 6695378 20970405 20512841
MESH:D008175 Lung Neoplasms Mustard Gas 8.698781369 3148597
MESH:D008175 Lung Neoplasms Tamoxifen 8.6918625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8819428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6711731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.6819453300
MESH:D008527 Medulloblastoma Tretinoin 2.8117453147
MESH:D008545 Melanoma Cisplatin 5.2311135225 17761969 18332650 17023156 12374674 16248763 18176117 16432458 12883367 15577323 12393984 16809738 18505091
MESH:D008545 Melanoma Tamoxifen 5.2312393984 19393235
MESH:D008545 Melanoma Tretinoin 5.2316752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 11.9115990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 11.9115990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6719513568
MESH:D008591 Meningomyelocele Tretinoin 4.5316940565
MESH:D008654 Mesothelioma Cisplatin 3.2717638057
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2516381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1619417148 15949261 19549372 11468182 14977855
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.8118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.5416882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.5417596541
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0516624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.833581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.8319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5419410462
MESH:D009369 Neoplasms Benzo(a)pyrene 8.5511141357
MESH:D009369 Neoplasms Cisplatin 8.5516773208
MESH:D009369 Neoplasms Tretinoin 8.5516594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1319200415 19189210 19196722
MESH:D009395 Nephritis, Interstitial Cisplatin 4.6315464296
MESH:D009421 Nervous System Malformations Tretinoin 3.879125849
MESH:D009436 Neural Tube Defects arsenic trioxide 7.4710525206
MESH:D009436 Neural Tube Defects Tretinoin 7.479142499
MESH:D009447 Neuroblastoma Cisplatin 3.498761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.4118514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.4120387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.818761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2520387270
MESH:D009503 Neutropenia Mustard Gas 4.0616761898 7688884
MESH:D010051 Ovarian Neoplasms arsenic trioxide 8.1019769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 8.1017225452 19769630 15464296 6897625
MESH:D010051 Ovarian Neoplasms Tretinoin 8.1016936753
MESH:D010146 Pain Acetaminophen 6.8116870215
MESH:D010146 Pain Tretinoin 6.8116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 12.5815580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 12.5819003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 12.5816540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 12.5815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7711578682
MESH:D010235 Paraganglioma arsenic trioxide 4.2519927285
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.4015464296
MESH:D010997 Pleural Neoplasms Cisplatin 5.4817638057
MESH:D011041 Poisoning Mustard Gas 3.8815727166
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.622563599
MESH:D011471 Prostatic Neoplasms marker/mechanism 17173048
MESH:D011471 Prostatic Neoplasms Androgens 1.8916998812 17909013 15389811
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8919131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8917292933
MESH:D011471 Prostatic Neoplasms Cholecalciferol 1.8917024972
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8915067354
MESH:D011507 Proteinuria Tretinoin 3.6916636307
MESH:D011537 Pruritus Ethinyl Estradiol 9.9215861022 16919318
MESH:D011537 Pruritus Mustard Gas 9.9218058305
MESH:D011625 Pterygium Tretinoin 4.9116723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.9517720292 17266442 10334151 17620002 17894541
MESH:D051437 Renal Insufficiency Cisplatin 4.5115464296
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1916283617 16116481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 10.6716646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 10.6714601052
MESH:D012871 Skin Diseases Mustard Gas 2.7316961503 12880345 15451306
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.6810029692 19755658
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.688532709
MESH:D012878 Skin Neoplasms Tretinoin 9.6816467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.4815464296
MESH:D013088 Spermatocele Ethinyl Estradiol 12.0116709447
MESH:D013088 Spermatocele Tamoxifen 12.0116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1519457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.4817007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 6.4820155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 6.4818396642 15958060 17522103
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.4818456281
MESH:D013274 Stomach Neoplasms Tretinoin 6.4817261132
MESH:D013736 Testicular Neoplasms Cisplatin 4.7217225452 15464296
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2215669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.3519014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.357505956
MESH:D013964 Thyroid Neoplasms Tretinoin 12.3516026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8616051514
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0815213294
MESH:D014376 Tuberculosis Tretinoin 3.2716040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 12.2020435036 11780464 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 12.2017053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 12.2017225452 12973940 15464296
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 12.2017572228 16712894 8653321
MESH:D014581 Urticaria Acetaminophen 3.0610982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 9.8316803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.8316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7416752155
MESH:D014625 Vaginal Neoplasms Cisplatin 4.7115577323
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6214671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.1516761959
MESH:D014839 Vomiting Cisplatin 4.8511897121
MESH:D009396 Wilms Tumor Tretinoin 4.0416287080
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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