Gene Symbol:	EYA1 ( BOP,BOR,MGC141875 )
Gene Full Name:	eyes absent homolog 1 (Drosophila)
Band:	8q13.3
Quick Links	Entrez ID:2138; OMIM: 601653; Uniprot ID:EYA1_HUMAN; ENSEMBL ID: ENSG00000104313; HGNC ID: 3519
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
C029424	hydrazine	hydrazine results in increased expression of EYA1 mRNA	increases expression	15282401
D009151	Mustard Gas	Mustard Gas results in increased expression of EYA1 mRNA	increases expression	15674843
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of EYA1 mRNA	affects binding\|increases activity\|increases expression	19710929

Disease ID	Disease Name	Direct Evidence	Inference Chemical Name	Inference Score	Publication
MESH:D055371	Acute Lung Injury		pirinixic acid	3.64	18653653
MESH:D018248	Adenoma, Liver Cell		pirinixic acid	4.22	16434500
MESH:D001249	Asthma		Mustard Gas	2.81	10378619
MESH:D001768	Blister		Mustard Gas	5.90	19167455
MESH:D001778	Blood Coagulation Disorders		pirinixic acid	3.63	19483382
MESH:D019280	Branchio-Oto-Renal Syndrome	marker/mechanism			12834866
MESH:C537106	Branchiootorenal syndrome 1	marker/mechanism
MESH:D001989	Bronchiolitis Obliterans		Mustard Gas	5.90	15286001
MESH:D029481	Bronchitis, Chronic		Mustard Gas	5.84	17687719 10378619
MESH:C535349	Cayler cardiofacial syndrome	marker/mechanism			15493068
MESH:D002779	Cholestasis		pirinixic acid	3.15	19176532
MESH:D000013	Congenital Abnormalities	marker/mechanism			10471511
MESH:D019465	Craniofacial Abnormalities	marker/mechanism			10471511
MESH:D003876	Dermatitis, Atopic		pirinixic acid	2.59	18249437
MESH:D004487	Edema		Mustard Gas	8.52	11428647 9260866 11402378 11428631
MESH:D004487	Edema		pirinixic acid	8.52	12083418
MESH:D004890	Erythema		Mustard Gas	5.90	9357497
MESH:D005234	Fatty Liver		pirinixic acid	3.25	19236843 20131406
MESH:D006314	Hearing Loss, Conductive	marker/mechanism			10471511
MESH:D006330	Heart Defects, Congenital	marker/mechanism			15493068
MESH:D006333	Heart Failure		pirinixic acid	2.78	20558911
MESH:D006529	Hepatomegaly		pirinixic acid	3.64	19176532 16221962 19772884 18467677
MESH:D006943	Hyperglycemia		pirinixic acid	3.63	20558911
MESH:D007249	Inflammation		Mustard Gas	2.98	11428620 11402378 16001271 9357497 9260866 11428631 11428647 17524151 8975870
MESH:D007333	Insulin Resistance		pirinixic acid	2.90	16306350
MESH:D008106	Liver Cirrhosis, Experimental		pirinixic acid	1.35	15474484
MESH:D008113	Liver Neoplasms		pirinixic acid	1.94	15890375 16377806 20007298
MESH:D008171	Lung Diseases		Mustard Gas	3.73	18702808 18161513
MESH:D008175	Lung Neoplasms		Mustard Gas	2.18	8781369 3148597
MESH:D009135	Muscular Diseases		pirinixic acid	4.16	16239165
MESH:D009203	Myocardial Infarction		pirinixic acid	2.29	19151258
MESH:D015428	Myocardial Reperfusion Injury		pirinixic acid	3.29	16411023
MESH:D009369	Neoplasms		pirinixic acid	2.12	17405874
MESH:D009503	Neutropenia		Mustard Gas	4.50	16761898 7688884
MESH:D009765	Obesity		pirinixic acid	1.89	20558911
OMIM:166780	OTOFACIOCERVICAL SYNDROME	marker/mechanism
MESH:D011041	Poisoning		Mustard Gas	4.32	15727166
MESH:D011537	Pruritus		Mustard Gas	4.83	18058305
MESH:D011658	Pulmonary Fibrosis		Mustard Gas	3.06	17620002 17894541 17720292 10334151 17266442
MESH:D015427	Reperfusion Injury		pirinixic acid	2.56	19058328
MESH:D012871	Skin Diseases		Mustard Gas	2.80	15451306 16961503 12880345

Desease Name
sleepiness
NEUROLOGICAL

Desease Name
Otofaciocervical syndrome
Anterior segment anomalies and cataract
Branchiootorenal syndrome
Branchiootorenal syndrome with cataract
Branchiootic syndrome

AutismKB 2.0

Annotation Detail for EYA1

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics