AutismKB 2.0

Annotation Detail for F2


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Basic Information Top
Gene Symbol:F2 ( PT )
Gene Full Name: coagulation factor II (thrombin)
Band: 11p11.2
Quick LinksEntrez ID:2147; OMIM: 176930; Uniprot ID:THRB_HUMAN; ENSEMBL ID: ENSG00000180210; HGNC ID: 3535
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
hsa04810Regulation of actin cytoskeleton
hsa04610Complement and coagulation cascades
Pathway IDPathway Name
Signaling by GPCR
Diabetes pathways
Metabolism of proteins
Hemostasis
Pathway IDPathway Name
200066Angiopoietin receptor Tie2-mediated signaling
200073FOXA2 and FOXA3 transcription factor networks
200115Syndecan-4-mediated signaling events
Pathway IDPathway Name
P00011Blood coagulation
Pathway IDPathway Name
500302Intrinsic Pathway
500303Common Pathway
500133Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Protei
500405Peptide ligand-binding receptors
500961Thrombin signalling through proteinase activated receptors (PARs)
500540Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
500541Gamma-carboxylation of protein precursors
500542Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi appar
500543Removal of aminoterminal propeptides from gamma-carboxylated proteins
500300Formation of Fibrin Clot (Clotting Cascade)
Related Diseases/Disorders Top
Desease IDDesease Name
Circulatory system diseases
Hematologic diseases
H00223Inherited thrombophilia
Desease IDDesease Name
1706Thrombophilia
1818Systemic scleroderma
1848Embryoma
1858Hemorrhagic disorder
1869Behcet syndrome
1894Abortion
1901Endometriosis
1904Diabetes mellitus
1997Dental plaque
1998Enteritis
2008Liver disease
2022Liver cancer
2081Pulmonary fibrosis
2039Hyperhomocysteinemia
2111Systemic infection
2146Lupus erythematosus
2187Nevus
2214Malignant glioma
2232Aseptic necrosis of bone
2236Cardiovascular disease
2237Neoplasm metastasis
Desease Name
HEMATOLOGICAL
elevated plasma prothrombin levels and an increase
Thrombosis
Venous Thrombosis
polycystic ovary syndrome
atherosclerosis, coronary
CARDIOVASCULAR
myocardial infarct
thrombosis, arterial
stroke, ischemic
Early occlusion of coronary by-pass
Branch retinal vein occlusion
hearing loss/deafness
factor V Leiden
vascular disease
bleeding complications
inflammatory bowel disease
IMMUNE
Behcet's Disease
pregnancy loss, recurrent
METABOLIC
Stroke
Venous Thromboembolism
antiphospholipid syndrome
thromboembolism, venous
cerebrovascular disease
REPRODUCTION
Spinal cord infarction and recurrent venous thrombosis
fetal loss
massive thrombosis
bilateral iliac vein thrombosis
No data
Desease Name
Hyperprothrombinemia
Dysprothrombinemia
Hypoprothrombinemia
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of F2 mRNAaffects expression 21346803
C044815 3-keto-desogestrel 3-keto-desogestrel promotes the reaction [F2 protein results in increased expression of F3 mRNA]increases expression|increases reaction 11733402
D000255 Adenosine Triphosphate calmidazolium affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]affects reaction|increases secretion 2030746
D000255 Adenosine Triphosphate F2 protein results in increased secretion of Adenosine Triphosphateincreases secretion 2030746
D000255 Adenosine Triphosphate Fendiline affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]affects reaction|increases secretion 2030746
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of F2 proteinaffects expression 20106945
D000638 Amiodarone Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein]decreases reaction|increases activity|increases expression 18974383
D000643 Ammonium Chloride Ammonium Chloride affects the expression of F2 mRNAaffects expression 16483693
D000661 Amphetamine Amphetamine promotes the reaction [F2 protein results in increased expression of F3 protein]increases expression|increases reaction 20118172
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased expression of F3 protein]affects cotreatment|decreases reaction|increases expression 19944065
C031942 argatroban argatroban binds to and results in decreased activity of F2 proteinaffects binding|decreases activity 15080313
16084352
18449412
D001218 Aspartame Aspartame analog results in decreased activity of F2 proteindecreases activity 15572260
D001218 Aspartame Aspartame results in decreased activity of F2 proteindecreases activity 15572260
C111479 BCH 2763 BCH 2763 results in decreased activity of F2 proteindecreases activity 9684808
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of F2 mRNAincreases expression 20440473
C095105 bexarotene bexarotene results in decreased expression of F2 mRNAdecreases expression 16648578
C074619 bivalirudin bivalirudin binds to and results in decreased activity of F2 proteinaffects binding|decreases activity 18449412
17696810
15155122
15080313
16084352
19124943
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 16845256
C074619 bivalirudin bivalirudin results in decreased activity of F2 proteindecreases activity 8456428
1290488
19644995
C074619 bivalirudin F2 protein results in increased cleavage of bivalirudinincreases cleavage 1290488
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased expression of SERPINE1 mRNA]decreases reaction|increases expression 9125671
9579636
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 9579636
C074619 bivalirudin bivalirudin inhibits the reaction [F2 protein results in increased secretion of SERPINE1 protein]decreases reaction|increases secretion 9125671
D015124 8-Bromo Cyclic Adenosine Monophosphate 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [F2 protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 9579636
C031938 calmidazolium calmidazolium affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]affects reaction|increases secretion 2030746
D002211 Capsaicin Capsaicin affects the expression of F2 proteinaffects expression 8285224
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased activity of F2 proteinincreases activity 12297134
C086276 cerivastatin cerivastatin inhibits the reaction [F2 protein results in decreased expression of ENTPD1 protein]decreases expression|decreases reaction 12067895
D002713 Chlorine Chlorine results in decreased expression of F2 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of F2 mRNAaffects cotreatment|affects expression 18636392
C055162 clopidogrel clopidogrel inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 17043144
D003474 Curcumin Curcumin inhibits the reaction [F2 protein results in increased expression of ITGA2B protein]decreases reaction|increases expression 18565277
D003474 Curcumin Curcumin inhibits the reaction [F2 protein results in increased expression of ITGB3 protein]decreases reaction|increases expression 18565277
D003474 Curcumin Curcumin inhibits the reaction [F2 protein results in increased expression of SELE protein]decreases reaction|increases expression 18565277
D003474 Curcumin Curcumin inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 18565277
D016572 Cyclosporine Cyclosporine results in decreased expression of F2 mRNAdecreases expression 20106945
D003871 Dermatan Sulfate [Dermatan Sulfate co-treated with SERPIND1 protein] results in decreased activity of F2 proteinaffects cotreatment|decreases activity 11805133
D003907 Dexamethasone Dexamethasone promotes the reaction [F2 protein results in increased expression of F3 mRNA]increases expression|increases reaction 11733402
D003907 Dexamethasone Dexamethasone promotes the reaction [F2 protein results in increased expression of F3 mRNA]increases expression|increases reaction 11733402
C023635 dienogest [Ethinyl Estradiol co-treated with dienogest] results in increased expression of F2 proteinaffects cotreatment|increases expression 15288212
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [F2 protein results in increased activity of F3 protein]decreases reaction|increases activity 19944065
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [F2 protein results in increased expression of F3 mRNA]decreases reaction|increases expression 19944065
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [F2 protein results in increased expression of F3 protein]decreases reaction|increases expression 19944065
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased activity of F3 protein]affects cotreatment|decreases reaction|increases activity 19944065
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased expression of F3 mRNA]affects cotreatment|decreases reaction|increases expression 19944065
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased expression of F3 protein]affects cotreatment|decreases reaction|increases expression 19944065
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein]affects cotreatment|decreases reaction|increases phosphorylation 19944065
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK9 protein]affects cotreatment|decreases reaction|increases phosphorylation 19944065
C454300 estradiol valerate-dienogest [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in increased expression of F2 proteinaffects cotreatment|increases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with dienogest] results in increased expression of F2 proteinaffects cotreatment|increases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in increased expression of F2 proteinaffects cotreatment|increases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of F2 proteinaffects cotreatment|decreases activity 16522526
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Gestodene] results in decreased expression of F2 proteinaffects cotreatment|decreases expression 15504374
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of F2 mRNAaffects cotreatment|decreases expression 17942748
D005275 Fendiline Fendiline affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]affects reaction|increases secretion 2030746
C025314 ferric citrate ferric citrate results in decreased activity of F2 proteindecreases activity 6421970
C020748 ferrous sulfate ferrous sulfate results in decreased activity of F2 proteindecreases activity 6421970
D005472 Fluorouracil Fluorouracil results in decreased expression of F2 mRNAdecreases expression 16709241
D005576 Forskolin Forskolin inhibits the reaction [F2 protein results in increased expression of SERPINE1 protein]decreases reaction|increases expression 9579636
C033273 Gestodene [Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of F2 proteinaffects cotreatment|decreases activity 16522526
C033273 Gestodene [Ethinyl Estradiol co-treated with Gestodene] results in decreased expression of F2 proteinaffects cotreatment|decreases expression 15504374
D006493 Heparin Heparin inhibits the reaction [F2 protein results in increased cleavage of F2R protein]decreases reaction|increases cleavage 19468011
D007501 Iron Iron results in decreased activity of F2 proteindecreases activity 6421970
C083544 lepirudin lepirudin binds to and results in decreased activity of F2 proteinaffects binding|decreases activity 15080313
18449412
D017258 Medroxyprogesterone Acetate Medroxyprogesterone Acetate promotes the reaction [F2 protein results in increased expression of F3 mRNA]increases expression|increases reaction 11733402
D017258 Medroxyprogesterone Acetate Medroxyprogesterone Acetate promotes the reaction [F2 protein results in increased expression of F3 mRNA]increases expression|increases reaction 11733402
C109573 melagatran melagatran binds to and results in decreased activity of F2 proteinaffects binding|decreases activity 16084352
C025589 ochratoxin A ochratoxin A results in decreased expression of F2 mRNAdecreases expression 16251485
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of F2 mRNAaffects cotreatment|affects expression 18636392
D017239 Paclitaxel anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased expression of F3 protein]affects cotreatment|decreases reaction|increases expression 19944065
D017239 Paclitaxel epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased activity of F3 protein]affects cotreatment|decreases reaction|increases activity 19944065
D017239 Paclitaxel epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased expression of F3 mRNA]affects cotreatment|decreases reaction|increases expression 19944065
D017239 Paclitaxel epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased expression of F3 protein]affects cotreatment|decreases reaction|increases expression 19944065
D017239 Paclitaxel epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein]affects cotreatment|decreases reaction|increases phosphorylation 19944065
D017239 Paclitaxel epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK9 protein]affects cotreatment|decreases reaction|increases phosphorylation 19944065
D017239 Paclitaxel [Paclitaxel co-treated with F2 protein] affects the localization of RELA proteinaffects cotreatment|affects localization 19944065
D017239 Paclitaxel [Paclitaxel co-treated with F2 protein] results in increased activity of F3 proteinaffects cotreatment|increases activity 19944065
D017239 Paclitaxel [Paclitaxel co-treated with F2 protein] results in increased expression of F3 mRNAaffects cotreatment|increases expression 19944065
D017239 Paclitaxel [Paclitaxel co-treated with F2 protein] results in increased expression of F3 proteinaffects cotreatment|increases expression 19944065
D017239 Paclitaxel [Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 proteinaffects cotreatment|increases phosphorylation 19944065
D017239 Paclitaxel [Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK9 proteinaffects cotreatment|increases phosphorylation 19944065
C020924 phenylalanyl-prolyl-arginine methyl chloride phenylalanyl-prolyl-arginine methyl chloride inhibits the reaction [F2 protein results in increased expression of FOS mRNA]decreases reaction|increases expression 18597608
C020924 phenylalanyl-prolyl-arginine methyl chloride phenylalanyl-prolyl-arginine methyl chloride inhibits the reaction [F2 protein results in increased expression of MYC mRNA]decreases reaction|increases expression 18597608
C060974 phosphatidylinositol 3,4,5-triphosphate F2 protein results in increased abundance of phosphatidylinositol 3,4,5-triphosphateincreases abundance 16051184
C060974 phosphatidylinositol 3,4,5-triphosphate resveratrol inhibits the reaction [F2 protein results in increased abundance of phosphatidylinositol 3,4,5-triphosphate]decreases reaction|increases abundance 16051184
C060980 phosphatidylinositol 3,4-diphosphate F2 protein results in increased abundance of phosphatidylinositol 3,4-diphosphateincreases abundance 16051184
C060980 phosphatidylinositol 3,4-diphosphate resveratrol inhibits the reaction [F2 protein results in increased abundance of phosphatidylinositol 3,4-diphosphate]decreases reaction|increases abundance 16051184
C037178 phosphatidylinositol 4-phosphate F2 protein results in increased abundance of phosphatidylinositol 4-phosphateincreases abundance 16051184
C037178 phosphatidylinositol 4-phosphate resveratrol inhibits the reaction [F2 protein results in increased abundance of phosphatidylinositol 4-phosphate]decreases reaction|increases abundance 16051184
D010716 Phosphatidylinositols F2 protein results in increased abundance of Phosphatidylinositolsincreases abundance 16051184
D010716 Phosphatidylinositols resveratrol inhibits the reaction [F2 protein results in increased abundance of Phosphatidylinositols]decreases reaction|increases abundance 16051184
D019269 Phosphatidylinositol 4,5-Diphosphate F2 protein results in increased abundance of Phosphatidylinositol 4,5-Diphosphateincreases abundance 16051184
D019269 Phosphatidylinositol 4,5-Diphosphate resveratrol inhibits the reaction [F2 protein results in increased abundance of Phosphatidylinositol 4,5-Diphosphate]decreases reaction|increases abundance 16051184
D011794 Quercetin Quercetin inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 14628445
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased abundance of phosphatidylinositol 3,4,5-triphosphate]decreases reaction|increases abundance 16051184
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased abundance of phosphatidylinositol 3,4-diphosphate]decreases reaction|increases abundance 16051184
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased abundance of Phosphatidylinositol 4,5-Diphosphate]decreases reaction|increases abundance 16051184
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased abundance of phosphatidylinositol 4-phosphate]decreases reaction|increases abundance 16051184
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased abundance of Phosphatidylinositols]decreases reaction|increases abundance 16051184
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased expression of SELP protein]decreases reaction|increases expression 16051184
C059514 resveratrol resveratrol inhibits the reaction [F2 protein results in increased phosphorylation of PLEK protein]decreases reaction|increases phosphorylation 16051184
D019821 Simvastatin Simvastatin inhibits the reaction [F2 protein results in decreased expression of ENTPD1 protein]decreases expression|decreases reaction 12067895
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of F2 mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of F2 mRNAincreases expression 16267337
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of F2 mRNAincreases expression 15644576
C524038 variegin protein, Amblyomma variegatum F2 protein results in increased cleavage of variegin protein, Amblyomma variegatumincreases cleavage 19644995
C524038 variegin protein, Amblyomma variegatum variegin protein, Amblyomma variegatum binds to and results in decreased activity of F2 proteinaffects binding|decreases activity 19644995
D014859 Warfarin F2 gene polymorphism affects the susceptibility to Warfarinaffects response to substance 14656880
C426686 ximelagatran ximelagatran binds to and results in decreased activity of F2 proteinaffects binding|decreases activity 16084352
15155122
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 6.7818926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.7815322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 2.9818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3517505938
MESH:D054058 Acute Coronary Syndrome bivalirudin 11.4519804226 10629409
MESH:D054058 Acute Coronary Syndrome clopidogrel 11.4519106084
MESH:D058186 Acute Kidney Injury Capsaicin 7.3718460982
MESH:D058186 Acute Kidney Injury resveratrol 7.3716538975
MESH:D055371 Acute Lung Injury Chlorine 3.7920601635
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 5.9520127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 5.9514692618
MESH:D000230 Adenocarcinoma Fluorouracil 5.9517638652
MESH:D000236 Adenoma Benzo(a)pyrene 5.596695378
MESH:D000236 Adenoma resveratrol 5.5915688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 2.8016835633
MESH:D019973 Alcohol-Related Disorders Curcumin 4.4917887948
MESH:D000505 Alopecia Capsaicin 4.2617569567
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.0716640825
MESH:D000544 Alzheimer Disease Curcumin 8.0615590663
MESH:D000544 Alzheimer Disease Iron 8.0616563566 16640825
MESH:D000544 Alzheimer Disease Ozone 8.0615513908
MESH:D000544 Alzheimer Disease resveratrol 8.0616162502 16183991
MESH:D019969 Amphetamine-Related Disorders Amphetamine 5.4716459022 15010207 18475255 16916582
MESH:D000740 Anemia Fluorouracil 11.9517963324 16511603 15504547
MESH:D000740 Anemia Iron 11.9516434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 11.9511748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.7217084956
MESH:D018798 Anemia, Iron-Deficiency Iron 4.1417375513 17162259 17163184 16569441 17147795
MESH:D000755 Anemia, Sickle Cell Aspartame 5.5011372003
MESH:D000756 Anemia, Sideroblastic Iron 4.2916910769
MESH:D000787 Angina Pectoris Fendiline 6.3112088766
MESH:D000855 Anorexia Amphetamine 4.5016084549 16101753 12005258 12183048
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.5019183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 7.5520041841 18218290 18057881
MESH:D001145 Arrhythmias, Cardiac Iron 7.5516604332
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.9011256880
MESH:D001169 Arthritis, Experimental Dexamethasone 10.1117659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 10.1115885639
MESH:D001169 Arthritis, Experimental resveratrol 10.1117115116
MESH:D001172 Arthritis, Rheumatoid Aspartame 6.6510777254
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.6516807698
MESH:D001172 Arthritis, Rheumatoid Ozone 6.6515570426
MESH:D001249 Asthma epigallocatechin gallate 4.6116516891
MESH:D001249 Asthma Ozone 4.6116373670 17854713
MESH:D001260 Ataxia Telangiectasia Iron 11.1715336622
MESH:D001260 Ataxia Telangiectasia Quercetin 11.1715336622
MESH:D050197 Atherosclerosis Curcumin 9.0118704882
MESH:D050197 Atherosclerosis Iron 9.0116632123 16640825
MESH:D050197 Atherosclerosis resveratrol 9.0117967414 16873680
MESH:D001281 Atrial Fibrillation Amiodarone 3.4619698954 18651412
MESH:D001321 Autistic Disorder Iron 2.8717352947
MESH:D001327 Autoimmune Diseases Curcumin 14.8919761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 14.8919761891
MESH:D001327 Autoimmune Diseases Quercetin 14.8919761891
MESH:D001424 Bacterial Infections Iron 4.6116640825
MESH:D001778 Blood Coagulation Disorders marker/mechanism 17721328
MESH:D001778 Blood Coagulation Disorders Amiodarone 12.5719483382
MESH:D001778 Blood Coagulation Disorders ferrous sulfate 12.576421970
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 12.5712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3715746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.0315867366
MESH:D001919 Bradycardia Capsaicin 4.4818207255
MESH:D002545 Brain Ischemia marker/mechanism 14753426
MESH:D002545 Brain Ischemia Capsaicin 13.8219211983
MESH:D002545 Brain Ischemia Curcumin 13.8216770732
MESH:D002545 Brain Ischemia resveratrol 13.8217600658
MESH:D001932 Brain Neoplasms Curcumin 3.4317596214
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 5.0417474063 20146248
MESH:D001943 Breast Neoplasms bexarotene 5.0416344269 16818667
MESH:D001943 Breast Neoplasms Curcumin 5.0419250217 18462866 18593918 16243823
MESH:D001943 Breast Neoplasms Fluorouracil 5.0416110121 16595493 19217205 18357371 15136595 16557594 18608205
MESH:D001943 Breast Neoplasms ochratoxin A 5.0411921183
MESH:D001943 Breast Neoplasms Paclitaxel 5.0415136595 11325840 18323546 16115903 16273361 18223236 16244791 18234424
MESH:D001943 Breast Neoplasms Quercetin 5.0418628248
MESH:D001943 Breast Neoplasms resveratrol 5.0417534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.0420435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.2118315731 14754758 17626835 15516495 18417511 16777450 19059883
MESH:D002100 Cachexia Ozone 4.1616183385
MESH:D002105 Cadmium Poisoning Quercetin 4.9516962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2116050911 16227642 16011737 15673190 16192424 15700767 18705752 15721981 3786805 10355542 16097048 16124888
MESH:D002276 Carcinoid Tumor Fluorouracil 4.0716051944
MESH:D002277 Carcinoma Curcumin 11.2618593918
MESH:D002277 Carcinoma Fluorouracil 11.2617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 11.2616835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 14.6516705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 14.6512907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 14.6519418558
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 14.6518788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 14.6517045692 18930000 16332177 17088986 16799960 17971768
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 14.6516313753
MESH:D006528 Carcinoma, Hepatocellular Quercetin 14.6519519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 14.6519321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.0116675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 5.0516247446
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.0518414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3817234771
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.7218695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 9.0820419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 9.0818462866
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 9.0817066447 16757204 18986760 16280240
MESH:D002294 Carcinoma, Squamous Cell resveratrol 9.0816227395
MESH:D006332 Cardiomegaly Quercetin 5.6319794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.6318670907 16120746 18850075
MESH:D009202 Cardiomyopathies Iron 3.6416640825
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 5.3715710769 19225199
MESH:D002311 Cardiomyopathy, Dilated Iron 5.3716604332
MESH:D002318 Cardiovascular Diseases clopidogrel 6.6020180610
MESH:D002318 Cardiovascular Diseases resveratrol 6.6015458977
MESH:D020212 Carotid Artery Injuries bivalirudin 6.0211316950
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.5018974383
MESH:D002386 Cataract Adenosine Triphosphate 7.3115003327
MESH:D002386 Cataract Simvastatin 7.3112518039
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 5.196135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 5.1912371664
MESH:D002543 Cerebral Hemorrhage Warfarin 5.2911061249
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.6716835633
MESH:D002779 Cholestasis Cyclosporine 6.3019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 6.3016919318 17110522 16105132 15861022 17681005 17333356 11677210
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.8316354765 15340226 12621046 15668235 8697196
MESH:D003092 Colitis Curcumin 7.9116782535 16804969 18200517
MESH:D003092 Colitis resveratrol 7.9116474422
MESH:D003103 Coloboma Curcumin 4.0218809619
MESH:D003110 Colonic Neoplasms Curcumin 12.1616340194 19359593
MESH:D003110 Colonic Neoplasms Dexamethasone 12.1615824018
MESH:D003110 Colonic Neoplasms Fluorouracil 12.1617287894 17725105 17172411 15001691 16340194 16510598 17018589 17016597 18772588 17169374
MESH:D003110 Colonic Neoplasms Iron 12.1616640825
MESH:D003110 Colonic Neoplasms Quercetin 12.1611134977 16640504 17191121 19440933 19056647 15741050 17148506
MESH:D003110 Colonic Neoplasms resveratrol 12.1616338953
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.2217454858 18949393 18802399 16391804 18383874 18288408 15148649 17016601 17695437 18448328 16282729 17401013 16303861 14970324 16524972 17255274 18509181 15289873 20501625 17594712 17094418 16331619
MESH:D015179 Colorectal Neoplasms Paclitaxel 4.2218802399
MESH:D015179 Colorectal Neoplasms Quercetin 4.2218852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 4.2216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5717141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.3318497527
MESH:D003327 Coronary Disease resveratrol 3.3616507316
MESH:D023903 Coronary Restenosis Warfarin 5.1212872399
MESH:D003328 Coronary Thrombosis bivalirudin 5.2218036681
MESH:D003371 Cough Capsaicin 4.5810350223
OMIM:122700 COUMARIN RESISTANCE Warfarin 5.2820579077 20497562
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.5217728286
MESH:D019465 Craniofacial Abnormalities ochratoxin A 3.5220036863
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.5210048152 20055451 15322242
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.4518551238
MESH:D003550 Cystic Fibrosis Simvastatin 4.4419747007
MESH:D007644 Darier Disease Fluorouracil 4.2116733453
MESH:D003731 Dental Caries Aspartame 6.338955999
MESH:D017449 Dermatitis, Allergic Contact Aspartame 5.9114996049
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.9112438553
MESH:D048909 Diabetes Complications bivalirudin 5.7618436116
MESH:D003920 Diabetes Mellitus Iron 3.9616640825 16604332
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.9619496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.9616873680
MESH:D003922 Diabetes Mellitus, Type 1 Iron 5.5516506275
MESH:D003922 Diabetes Mellitus, Type 1 Warfarin 5.5518772604
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 8.8018403477
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 8.8016988119
MESH:D003924 Diabetes Mellitus, Type 2 Iron 8.8016506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 8.8017107852
MESH:D003928 Diabetic Nephropathies Curcumin 12.4618204486
MESH:D003928 Diabetic Nephropathies resveratrol 12.4616286809
MESH:D003928 Diabetic Nephropathies Warfarin 12.4612644472
MESH:D003967 Diarrhea Dexamethasone 3.167237001
MESH:D003875 Drug Eruptions Warfarin 5.4114723717
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 7.2218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Amiodarone 7.2218218290 15265979
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 7.227179309 21278145 7120509 10915739 10092053 17522070 15998439 16227642 15027814 7440962 3786805 9327722 6884620 2869522 6623471 4309450 11566570 19085960 3732212 16177239 19336974 15968718
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 7.2220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.3211462148
MESH:D004381 Duodenal Ulcer Capsaicin 7.7911535926 10671773
MESH:D004381 Duodenal Ulcer Curcumin 7.7917351913
MESH:D004417 Dyspnea Chlorine 4.0320016425
MESH:D004485 Eczema Dexamethasone 3.9112438553
MESH:D004487 Edema Dexamethasone 8.5819703484
MESH:D004487 Edema resveratrol 8.588985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.5812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.3115322242 18230668 16714409
MESH:D016769 Embolism and Thrombosis argatroban 26.7716084352
MESH:D016769 Embolism and Thrombosis BCH 2763 26.779684808
MESH:D016769 Embolism and Thrombosis bivalirudin 26.7716084352
MESH:D016769 Embolism and Thrombosis melagatran 26.7716084352
MESH:D016769 Embolism and Thrombosis ximelagatran 26.7716084352
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.2912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 7.2917872969
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.5210568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.2817923197
MESH:D004893 Erythema Nodosum Aspartame 6.339324739
MESH:D004935 Esophageal Diseases Capsaicin 5.1219566590
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.2216530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.2215173087 17638652 16337965 16785472 16481741
MESH:D004938 Esophageal Neoplasms Paclitaxel 6.2216481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5711564622
MESH:D005141 Eyelid Diseases Aspartame 5.7814996049
MESH:D005221 Fatigue Amphetamine 5.0219890266
MESH:D005234 Fatty Liver Amiodarone 23.9814986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 23.9816045604 12631006 19224547 12795759 61145 15959796 17595544 16239168
MESH:D005234 Fatty Liver Curcumin 23.9819297423
MESH:D005234 Fatty Liver Cyclosporine 23.9819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.9815345470
MESH:D005234 Fatty Liver Iron 23.9816640825
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8911858732
MESH:D005334 Fever Aspartame 4.829630831
MESH:D005355 Fibrosis Carbon Tetrachloride 21.7418705752
MESH:D005355 Fibrosis Curcumin 21.7418705752
MESH:D005355 Fibrosis Cyclosporine 21.7412168785 12639820
MESH:D005355 Fibrosis Quercetin 21.7419474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.7420067830
MESH:D005621 Friedreich Ataxia Iron 4.8616604332 16640825
MESH:D005739 Gas Poisoning Chlorine 4.4220016425
MESH:D006471 Gastrointestinal Hemorrhage Warfarin 6.1211794436
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.1218462866
MESH:D005776 Gaucher Disease Warfarin 5.4012359135
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.638708960
MESH:D005909 Glioblastoma Capsaicin 9.8018405923
MESH:D005909 Glioblastoma Curcumin 9.8017596214
MESH:D005909 Glioblastoma Quercetin 9.8019804834
MESH:D005910 Glioma Fluorouracil 5.2916145905
MESH:D005910 Glioma Quercetin 5.2917643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0010696789
MESH:D006258 Head and Neck Neoplasms Curcumin 6.6018462866 18829502
MESH:D006258 Head and Neck Neoplasms Fluorouracil 6.6015102660 18337622 15162350
MESH:D006356 Heartburn Capsaicin 5.1219566590
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.3220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.3210048152 11294989
MESH:D006406 Hematoma Warfarin 6.1217493413
MESH:D006432 Hemochromatosis Iron 4.0517053826 16640825 16604332 16574947 17255318 17236123
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.8415720958
MESH:D006470 Hemorrhage bivalirudin 14.5619147609 16125490 18436116 19281522 19360860 16598112
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 14.5611000095
MESH:D006470 Hemorrhage Warfarin 14.5618429757
MESH:D006486 Hemosiderosis Iron 4.6216604332
MESH:D006505 Hepatitis Carbon Tetrachloride 3.0519900420 19110552
MESH:D006525 Hepatitis, Viral, Human Iron 4.8716640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.3717182432
MESH:D006529 Hepatomegaly Amiodarone 11.3215265979
MESH:D006529 Hepatomegaly Iron 11.3216890145
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 11.3215340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4717701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.847520565
MESH:D006561 Herpes Simplex resveratrol 3.6016876885
MESH:D015658 HIV Infections Iron 3.3416597321
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.458697196 16959395 15340226 18606429 16354765
MESH:D006930 Hyperalgesia Capsaicin 3.8717434803 17043245
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9516899240
MESH:D006937 Hypercholesterolemia Amiodarone 12.388137927 9751232
MESH:D006937 Hypercholesterolemia Curcumin 12.3818704882
MESH:D006937 Hypercholesterolemia resveratrol 12.3817188708
MESH:D006943 Hyperglycemia Quercetin 3.5211834736 18262572
MESH:D006948 Hyperkinesis Amphetamine 4.8514960337 1977408
MESH:D006949 Hyperlipidemias resveratrol 3.4916873680
MESH:D006938 Hyperlipoproteinemia Type II Simvastatin 4.7416238680
MESH:D006973 Hypertension Aspartame 13.6418708962
MESH:D006973 Hypertension Cyclosporine 13.6410903974
MESH:D006973 Hypertension Dexamethasone 13.6417042910
MESH:D006973 Hypertension Quercetin 13.6418356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 13.6418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5215338365
MESH:D006976 Hypertension, Pulmonary Warfarin 4.3812359135
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.7917488730
MESH:D007006 Hypogonadism Iron 3.9816640825
MESH:D007020 Hypoprothrombinemias marker/mechanism
MESH:D007021 Hypospadias Ethinyl Estradiol 3.2416945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 9.7917991464 18020914
MESH:D007037 Hypothyroidism Iron 9.7916640825
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0817600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.0917937319
MESH:D007249 Inflammation bivalirudin 15.6416125490
MESH:D007249 Inflammation Capsaicin 15.6416956363
MESH:D007249 Inflammation Curcumin 15.6418403477 16956363 17151092
MESH:D007249 Inflammation Dexamethasone 15.6411099482 8960868
MESH:D007249 Inflammation resveratrol 15.6416366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.6412200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9418596194 18200517
MESH:D007251 Influenza, Human Quercetin 9.2216624496
MESH:D007251 Influenza, Human resveratrol 9.2216624496
MESH:D007414 Intestinal Neoplasms Curcumin 3.7110783313
MESH:D019189 Iron Metabolism Disorders Iron 4.5017163184
MESH:D007511 Ischemia bivalirudin 5.4518436116
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.8116580747
MESH:D007627 Keloid Quercetin 4.3817086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.8515604871
MESH:D007674 Kidney Diseases Aspartame 11.6311409539
MESH:D007674 Kidney Diseases Cyclosporine 11.6310903974 18776723 8314463
MESH:D007674 Kidney Diseases ochratoxin A 11.6311409539
MESH:D007674 Kidney Diseases Quercetin 11.6316962696
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 13.9116705839
MESH:D007680 Kidney Neoplasms Cyclosporine 13.9112371664
MESH:D007680 Kidney Neoplasms Fluorouracil 13.9116985049
MESH:D007680 Kidney Neoplasms ochratoxin A 13.9116251485
MESH:D007889 Leiomyoma Curcumin 4.0318555241
MESH:D007938 Leukemia Curcumin 5.5618462866
MESH:D007938 Leukemia Quercetin 5.5617468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.6816106398
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 4.7916972261
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.1816087638
MESH:D015458 Leukemia, T-Cell Curcumin 4.2116106398
MESH:D020961 Lewy Body Disease Iron 4.8616563566
MESH:D008064 Lipidoses Amiodarone 3.0815342952 17567588
MESH:D008080 Liposarcoma Paclitaxel 4.2817353645
MESH:D054068 Livedo Reticularis Warfarin 6.1218280355
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.7816943688 17157831 11408273 21278145 11903743 16221502 17174718 17334410 16239168
MESH:D008103 Liver Cirrhosis Iron 5.7816640825
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.3718006644 11481614 18277467 17900296 17922224 15052691 15925388 18472332 18054572 16097048 12632514 14716833 12445418 18418968 18251166 15650968 16015684 16027843 18376398 12667390 17805973 12958196 15730626 14724832 15931870 12609069 15338365 18395095 17708605 15123356 17714472 12445421 16248980 17640975 14716496 15362042 17761835 17766677 15673190 15959796 14512876 18317297 15370692 20821823 12666154 16192424 17823541 18187930 16638106 17565644 18210741 18420326 17698563 17481882 12389079 18339082 14620537 12586293 12546737 16116963 18395914 18481824 17557913 18429990 17721639 17944888 12898905 15893842 18279442 12741479 18412020 12632512 15818738 15996030 10355542 16011737 13678700 16136751 18205269 18705752 17869086 12649538 17525996 18472094 16033810 18263696 18166357 17976157 15057751 18156304 14748882 15876570 17631135
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 9.3717355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.3716718785
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 9.3717481882
MESH:D008106 Liver Cirrhosis, Experimental Heparin 9.3716904936
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 9.3712741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.3712878042
MESH:D008107 Liver Diseases Capsaicin 5.6516956363
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.6517285989 15720792 16246199 16964402 15830285
MESH:D008107 Liver Diseases Curcumin 5.6516956363
MESH:D008108 Liver Diseases, Alcoholic Iron 4.4417207112 16737972
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.1814706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 24.947678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 24.942125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 24.9421137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 24.9419294768
MESH:D008113 Liver Neoplasms Fluorouracil 24.9416603448 17045692 15113037 18383874
MESH:D008113 Liver Neoplasms Iron 24.9420302851 16640825
MESH:D008113 Liver Neoplasms Quercetin 24.9418980244
MESH:D008113 Liver Neoplasms resveratrol 24.9419073162 19812893 20405173 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 24.9416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 14.556135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 14.558603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.5512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Quercetin 14.5519519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.5512151625
MESH:D008133 Long QT Syndrome Amiodarone 3.1317391786 11989578 15350150
MESH:D008171 Lung Diseases Amiodarone 6.2312587719
MESH:D008171 Lung Diseases Ozone 6.238266340 19066396
MESH:D017563 Lung Diseases, Interstitial Amiodarone 3.8918516814
MESH:D055370 Lung Injury Ozone 3.2920417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 15.6814755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 15.6818520028 6695378 20464547 20064080 18569708 20135361 18816296 20869020 17053015
MESH:D008175 Lung Neoplasms bexarotene 15.6817849452
MESH:D008175 Lung Neoplasms Curcumin 15.6819359593 18462866 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 15.6815824018 11195469
MESH:D008175 Lung Neoplasms Fluorouracil 15.6815246190
MESH:D008175 Lung Neoplasms Iron 15.6816640825
MESH:D008175 Lung Neoplasms Ozone 15.687614698 8597069
MESH:D008175 Lung Neoplasms Quercetin 15.6816280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 15.6819555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.2115086387
MESH:D008223 Lymphoma Curcumin 3.1618462866
MESH:D016393 Lymphoma, B-Cell resveratrol 3.7617088997
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 7.3914749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.3914749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.1216173963
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.5811161223
MESH:D008268 Macular Degeneration Iron 3.6316640825
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.6715688416
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 8.0319196722 19196723 15591091
MESH:D008325 Mammary Neoplasms, Experimental ochratoxin A 8.0311921183
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 8.038985016 11606380
MESH:D008545 Melanoma Curcumin 6.2617885582 18462866
MESH:D008545 Melanoma epigallocatechin gallate 6.2611746506 17992120
MESH:D008545 Melanoma Paclitaxel 6.2616342250 12025231 12040289
MESH:D008545 Melanoma resveratrol 6.2617992120
MESH:D008569 Memory Disorders Curcumin 3.6017263510
MESH:D008659 Metabolic Diseases resveratrol 3.8517112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.1916801185
MESH:D008679 Metaplasia Ozone 4.5110496685
MESH:D008850 Microphthalmos ochratoxin A 5.2420036863
MESH:D008881 Migraine Disorders Aspartame 4.4618627677 10792367
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.0116381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.0116757204 18986760
MESH:D009101 Multiple Myeloma Capsaicin 18.1517505005
MESH:D009101 Multiple Myeloma Curcumin 18.1519372569
MESH:D009101 Multiple Myeloma Dexamethasone 18.1515744524 15867202 16118317
MESH:D009101 Multiple Myeloma Paclitaxel 18.1514749477
MESH:D009101 Multiple Myeloma resveratrol 18.1514749477 17164350 16267019 16490592 17935668 17049120
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.0817086897
MESH:D009134 Muscular Atrophy, Spinal Curcumin 17.7817962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 17.7817962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 17.7817962980
MESH:D009181 Mycoses Amiodarone 11.1617974566 12754197
MESH:D009181 Mycoses Iron 11.1616640825
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.189809623
MESH:D009203 Myocardial Infarction Quercetin 5.1219595682
MESH:D009203 Myocardial Infarction resveratrol 5.1217188708 16456233 16525036 16317513 17125593 17015251
MESH:D017202 Myocardial Ischemia bivalirudin 18.0910562259
MESH:D017202 Myocardial Ischemia Iron 18.0916604332
MESH:D017202 Myocardial Ischemia resveratrol 18.0917125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 18.0912213967
MESH:D015428 Myocardial Reperfusion Injury Iron 7.4116604332
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.4119207477
MESH:D009205 Myocarditis resveratrol 4.1817322642
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.037678174 18551238
MESH:D009336 Necrosis Warfarin 9.0314723717
MESH:D009361 Neoplasm Invasiveness Curcumin 3.8218495463
MESH:D009362 Neoplasm Metastasis clopidogrel 5.6811875746
MESH:D009362 Neoplasm Metastasis Paclitaxel 5.6815867366
MESH:D009369 Neoplasms Aspartame 9.3316507461
MESH:D009369 Neoplasms Benzo(a)pyrene 9.3311141357
MESH:D009369 Neoplasms Fluorouracil 9.3318239605 18600527 16928823
MESH:D009369 Neoplasms Quercetin 9.3315185748
MESH:D009374 Neoplasms, Experimental resveratrol 3.448985016
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 9.1619196722
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.1612497104
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.8517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.8419348381 18481113
MESH:D009404 Nephrotic Syndrome Iron 7.8417178036
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 2.6614600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.0318462866
MESH:D009436 Neural Tube Defects ochratoxin A 4.0520036863
MESH:D019636 Neurodegenerative Diseases Amphetamine 11.6415183010
MESH:D019636 Neurodegenerative Diseases Iron 11.6417296847 16604332
MESH:D019636 Neurodegenerative Diseases resveratrol 11.6417652729
MESH:D020078 Neurogenic Inflammation Capsaicin 14.8017961222
MESH:D020078 Neurogenic Inflammation Quercetin 14.8017929310
MESH:D020078 Neurogenic Inflammation resveratrol 14.8017929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0316436463
MESH:D009765 Obesity Capsaicin 4.5719056576
MESH:D009765 Obesity Curcumin 4.5719297423
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.9316049721
MESH:D010003 Osteoarthritis Aspartame 7.179630831
MESH:D010003 Osteoarthritis Iron 7.1716640825
MESH:D010014 Osteolysis Paclitaxel 4.4015867366
MESH:D010024 Osteoporosis Curcumin 6.3118719352
MESH:D010024 Osteoporosis Iron 6.3116640825 16648989
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.4119495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.4117513867
MESH:D010051 Ovarian Neoplasms Curcumin 9.5818462866 19020741
MESH:D010051 Ovarian Neoplasms Medroxyprogesterone Acetate 9.5817393432
MESH:D010051 Ovarian Neoplasms Paclitaxel 9.5811161223
MESH:D010051 Ovarian Neoplasms Quercetin 9.5819005980
MESH:D010146 Pain Aspartame 6.279630831
MESH:D010146 Pain Capsaicin 6.2717084039 16996476 17043245 17434803 19081190 18987195
MESH:D010190 Pancreatic Neoplasms Curcumin 7.3017440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms Fluorouracil 7.3016929163 15113037 19003803 16500647
MESH:D010190 Pancreatic Neoplasms Quercetin 7.3016965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1511578682
MESH:D010212 Papilloma Iron 3.9212065085
MESH:D020447 Parasomnias Iron 5.4217352947
MESH:D010300 Parkinson Disease Iron 3.0816563566 16640825
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6512520081
MESH:D010538 Peritonitis Ozone 3.5716369182
MESH:D010900 Pituitary Diseases Iron 5.0816604332
MESH:D011014 Pneumonia Ozone 3.8118929643 18007984 18381685
MESH:D011041 Poisoning Iron 3.7616604332
MESH:D011085 Polycystic Ovary Syndrome Simvastatin 4.8317105841
MESH:D017119 Porphyria Cutanea Tarda Iron 9.1816640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.1818163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.4612371664
MESH:D011230 Precancerous Conditions Quercetin 7.4619056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.1921297632
MESH:D011225 Pre-Eclampsia Iron 3.9716640825
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 7.6616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.6611222880 11118676 11399792 11896295
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8817292933
MESH:D011471 Prostatic Neoplasms Curcumin 1.8811398177 18226269 15129424 12497104 18156803 10851300 18769126
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8818626508 19082440
MESH:D011471 Prostatic Neoplasms Paclitaxel 1.8816356831 17172428 17136230 16729912
MESH:D011471 Prostatic Neoplasms Quercetin 1.8817292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 1.8816731767 15767336 17675339 17718901 17636462 17804756
MESH:D020151 Protein C Deficiency Warfarin 5.7618376272
MESH:D011528 Protozoan Infections Iron 5.4216640825
MESH:D011537 Pruritus Ethinyl Estradiol 2.7415861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.0016882103
MESH:D011655 Pulmonary Embolism Warfarin 5.7619300499
MESH:D011656 Pulmonary Emphysema Curcumin 4.0219168576
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.6011597910 12832656 12490602
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5118286688 15538739 18722050 16160472
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.9916325855
MESH:D015427 Reperfusion Injury Capsaicin 6.0918460982 19211983
MESH:D015427 Reperfusion Injury resveratrol 6.0916314181 17520802 16317513 17058453 15827377
MESH:D012120 Respiration Disorders Chlorine 4.6218579056
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 7.5218379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 7.5211700416 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2818990726
MESH:D012148 Restless Legs Syndrome Iron 4.1016930377
MESH:D012170 Retinal Vein Occlusion clopidogrel 5.5519371211
MESH:D012509 Sarcoma Curcumin 3.6118462866
MESH:D012554 Schistosomiasis japonica Quercetin 4.9516862918
MESH:D012640 Seizures 2,6-dinitrotoluene 2.1518551238
MESH:D018805 Sepsis Curcumin 3.5918389075
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.5018724381
MESH:D012851 Sinus Thrombosis, Intracranial marker/mechanism 12269725
MESH:D012851 Sinus Thrombosis, Intracranial Heparin 10.9112269725
MESH:D012851 Sinus Thrombosis, Intracranial Warfarin 10.9112269725
MESH:D012859 Sjogren's Syndrome Aspartame 5.9816800424
MESH:D017445 Skin Diseases, Vascular marker/mechanism 17535202
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 11.0510029692 19755658
MESH:D012878 Skin Neoplasms Iron 11.0512065085
MESH:D012878 Skin Neoplasms resveratrol 11.058985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.0516192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.3516709447
MESH:D019956 Stereotypic Movement Disorder Amphetamine 5.831977408
MESH:D013272 Stomach Diseases Dexamethasone 3.7415472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.032093021 20155912
MESH:D013274 Stomach Neoplasms Fluorouracil 3.0316424979 19084572 18396642 17498489 17522103 16951190 18567086 19015929 17172411 15786421
MESH:D013274 Stomach Neoplasms Paclitaxel 3.0318506536 18396642
MESH:D013276 Stomach Ulcer Amiodarone 9.1718087811
MESH:D013276 Stomach Ulcer Curcumin 9.1716631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 9.1715138204
MESH:D020521 Stroke marker/mechanism
MESH:D020521 Stroke bivalirudin 8.2814683561
MESH:D020521 Stroke Warfarin 8.2819300499
OMIM:601367 STROKE, ISCHEMIC marker/mechanism
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9716321402
MESH:D013398 Sudden Infant Death Iron 4.8716640825
MESH:D013610 Tachycardia Amiodarone 3.7411238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.6419225199
MESH:D024801 Tauopathies Paclitaxel 4.2316930453
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 5.1317997062
MESH:D013921 Thrombocytopenia argatroban 19.1416893407
MESH:D013921 Thrombocytopenia Aspartame 19.1417534100
MESH:D013921 Thrombocytopenia bivalirudin 19.1416651880 16893407
MESH:D013921 Thrombocytopenia Heparin 19.1416893407 16651880
MESH:D013923 Thromboembolism Warfarin 5.5718698879 16960144
MESH:D019851 Thrombophilia marker/mechanism
MESH:D019851 Thrombophilia Ethinyl Estradiol 15.3311994571
MESH:D019851 Thrombophilia Gestodene 15.3311994571
MESH:D019851 Thrombophilia Warfarin 15.3317493413
MESH:D013927 Thrombosis marker/mechanism 17245631
MESH:D013927 Thrombosis argatroban 34.9314593979 16893407
MESH:D013927 Thrombosis bivalirudin 34.938456428 16893407 15979436 9125671 14593979
MESH:D013927 Thrombosis Ethinyl Estradiol 34.9315669648
MESH:D013927 Thrombosis Gestodene 34.9315669648
MESH:D013927 Thrombosis Heparin 34.9316893407
MESH:D013927 Thrombosis lepirudin 34.9314593979
MESH:D013927 Thrombosis Warfarin 34.9319300499 11518727 17672075 17245631 11307788 15720958
MESH:D013959 Thyroid Diseases Amiodarone 10.0719731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 10.0712697716
MESH:D013971 Thyrotoxicosis Amiodarone 4.2918020914 19584973
MESH:D014062 Tongue Neoplasms Fluorouracil 8.2916280240
MESH:D014062 Tongue Neoplasms resveratrol 8.2916227395
MESH:D016171 Torsades de Pointes Amiodarone 3.6117467628 11989578
MESH:D014376 Tuberculosis Iron 3.7016597321
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 9.7516049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 9.7517053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 9.7518593936
MESH:D001749 Urinary Bladder Neoplasms Quercetin 9.7516720314
MESH:D014565 Urogenital Neoplasms Curcumin 4.6818462866
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.7310091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 7.9216803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 7.9217473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.6614692618
MESH:D014594 Uterine Neoplasms resveratrol 7.6617044934
MESH:D014605 Uveitis Cyclosporine 9.791336536
MESH:D014605 Uveitis Dexamethasone 9.791336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0012125929
MESH:D014657 Vasculitis Heparin 10.9120337814
MESH:D014657 Vasculitis Warfarin 10.9120337814
MESH:D054556 Venous Thromboembolism Warfarin 5.7718776969
MESH:D020246 Venous Thrombosis marker/mechanism 12296757 19920886
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 9.0014671159 15869587
MESH:D020246 Venous Thrombosis Warfarin 9.0014723717 15733061
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.7317488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6515886252
MESH:D014985 Xerophthalmia Cyclosporine 3.8517120751
Pathway ID Pathway Name
KEGG:04610 Complement and coagulation cascades
REACT:15380 Diabetes pathways
REACT:604 Hemostasis
REACT:17015 Metabolism of proteins
KEGG:04080 Neuroactive ligand-receptor interaction
KEGG:04810 Regulation of actin cytoskeleton
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA157
    • No data
    Releated disease ID Related disease Name
    PA447298venous thromboembolism
    PA446832Endotoxemia
    PA446974Choroidal Neovascularization
    PA447276Thrombosis of cerebral veins
    PA445019Myocardial Infarction
    Releated drug ID Related drug Name
    PA448497aspirin
    PA451906warfarin
    PA450952phospholipids
    PA164768822chlorotrianisene
    PA164754789conjugated estrogens
    PA164745534dienestrol
    PA449307diethylstilbestrol
    PA449503estradiol
    PA449509estrogens
    PA449512estrone
    PA449527ethinyl estradiol
    PA448976choline
    PA448478l-arginine
    PA450635nitric oxide
    PA449470epinephrine
    PA452637hormonal contraceptives for systemic use
    PA451871verteporfin
    PA450651norethindrone
    PA449509estrogens
    PA164745516argatroban
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00001 antagonist Lepirudin Anticoagulants;Antithrombotic Agents;Fibrinolytic Agents
    DB00006 antagonist Bivalirudin Anticoagulants;Antithrombotic Agents
    DB00025 - Antihemophilic Factor Coagulants;Thrombotic Agents
    DB00055 - Drotrecogin alfa Antisepsis Agents
    DB00100 - Coagulation Factor IX Coagulants;Thrombotic Agents
    DB00170 activator Menadione Dietary supplement;Micronutrient;Antifibrinolytic Agents;Vitamins/minerals;Vitamins
    DB00278 inhibitor Argatroban Anticoagulants;Platelet Aggregation Inhibitors
    DB01123 other/unknown Triple Dye Anti-Infective Agents, Local;Anti-Infectives, local
    DB01766 - Beta-(2-Naphthyl)-Alanine
    DB01767 - Hemi-Babim
    DB02193 - 2-(2-Hydroxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine
    DB02351 inhibitor Hirulog Anticoagulants;Antithrombotics
    DB02723 - 4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-Amide
    DB03136 - 4-Iodobenzo[B]Thiophene-2-Carboxamidine
    DB03159 - CRA_8696
    DB03847 - Gamma-Carboxy-Glutamic Acid
    DB03865 - 6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine
    DB04136 - Lysophosphotidylserine
    DB04591 - N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINE
    DB04697 - TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE
    DB04722 - 2-(3-CHLORO-6-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-1-OXIDOPYRIDIN-2-YL)-N-[1-(3-CHLOROPHENYL)ETHYL]ACETAMIDE
    DB04771 - 1-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANE
    DB04772 - 1-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANE
    DB04786 antagonist Suramin Antineoplastic Agents;Trypanocidal Agents;Antinematodal Agents
    DB04898 inhibitor Ximelagatran Anticoagulants;Antithrombotic Agents
    DB06695 antagonist Dabigatran etexilate Anticoagulants;Antithrombotic Agents;Antithrombotics
    DB06838 - methyl L-phenylalaninate
    DB06841 - D-phenylalanyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl)butyl]-L-prolinamide
    DB06845 - (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide
    DB06850 - (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide
    DB06853 - N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
    DB06854 - 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE
    DB06858 - N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
    DB06859 - N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE
    DB06861 - 6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE
    DB06865 - 6-CARBAMIMIDOYL-2-[2-HYDROXY-6-(4-HYDROXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID
    DB06866 - 6-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID
    DB06868 - N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide
    DB06869 - 1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE
    DB06878 - 1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide
    DB06911 - D-leucyl-N-(3-chlorobenzyl)-L-prolinamide
    DB06919 - D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide
    DB06929 - 1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
    DB06936 - N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide
    DB06942 - N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
    DB06947 - 1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide
    DB06996 - D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
    DB07005 - D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide
    DB07016 - (3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline
    DB07027 - D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide
    DB07083 - beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide
    DB07088 - (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide
    DB07091 - (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide
    DB07095 - (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide
    DB07105 - 2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE
    DB07120 - N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINE
    DB07128 - N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINE
    DB07131 - (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide
    DB07133 - D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide
    DB07143 - D-phenylalanyl-N-benzyl-L-prolinamide
    DB07165 - N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE
    DB07190 - 3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide
    DB07211 - (2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE
    DB07277 - 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE
    DB07278 - 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDE
    DB07279 - N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE
    DB07353 - 4-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOL
    DB07366 - 2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
    DB07376 - 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)
    DB07400 - 1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE
    DB07440 - 4-TERT-BUTYLBENZENESULFONIC ACID
    DB07461 - 3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE
    DB07508 - 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE
    DB07515 - 1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL
    DB07521 - 6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL
    DB07522 - N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE
    DB07527 - N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE
    DB07548 - 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE
    DB07549 - 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDE
    DB07550 - 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDE
    DB07639 - 3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER
    DB07658 - AC-(D)PHE-PRO-BOROLYS-OH
    DB07659 - AC-(D)PHE-PRO-BOROHOMOLYS-OH
    DB07660 - AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH
    DB07665 - N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide
    DB07718 - 3-(4-HYDROXY-PHENYL)PYRUVIC ACID
    DB07741 - 4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE
    DB07796 - (3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE
    DB07809 - 4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE
    DB07897 - 1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE
    DB07934 - [[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE
    DB07944 - N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE
    DB07946 - N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide
    DB08061 - 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE
    DB08062 - 3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE
    DB08152 - {(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate
    DB08187 - METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE
    DB08254 - 2-NAPHTHALENESULFONIC ACID
    DB08422 - [PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE
    DB08546 - 4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE
    DB08624 - BENZOTHIAZOLE
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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