AutismKB 2.0

Annotation Detail for F7


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Basic Information Top
Gene Symbol:F7 ( - )
Gene Full Name: coagulation factor VII (serum prothrombin conversion accelerator)
Band: 13q34
Quick LinksEntrez ID:2155; OMIM: 227500; Uniprot ID:FA7_HUMAN; ENSEMBL ID: ENSG00000057593; HGNC ID: 3544
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04610Complement and coagulation cascades
Pathway IDPathway Name
Metabolism of proteins
Hemostasis
No data
Pathway IDPathway Name
P00005Angiogenesis
P00011Blood coagulation
Pathway IDPathway Name
500301Extrinsic Pathway
500540Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
500541Gamma-carboxylation of protein precursors
500542Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi appar
500543Removal of aminoterminal propeptides from gamma-carboxylated proteins
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1858Hemorrhagic disorder
1944Breast cancer
2097Hyperlipidemia
2111Systemic infection
2120Rabies
2236Cardiovascular disease
2237Neoplasm metastasis
Desease Name
HEMATOLOGICAL
plasma factor VII activity and antigen levels
atherosclerosis, coronary
cerebral infarct
blood pressure, arterial
CARDIOVASCULAR
Coronary Artery Disease
myocardial infarct
heart disease, ischemic
stroke, ischemic
Factor VII
cardiac death myocardial infarct
METABOLIC
obesity
Low plasma levels of factor VIIc
factor VII levels
No data
Desease Name
Myocardial infarction, decreased susceptibility to
Factor VII deficiency
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C524063 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [[F3 protein co-treated with F7 protein] results in increased expression of BCL2 protein]affects cotreatment|decreases reaction|increases expression 18325115
D000082 Acetaminophen Acetaminophen affects the expression of F7 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of F7 mRNAaffects expression 16483693
C010680 antibiotic G 418 antibiotic G 418 results in increased expression of and results in increased activity of F7 proteinincreases activity|increases expression 16706976
C034528 CycloProvera CycloProvera results in decreased expression of F7 proteindecreases expression 14561536
C023635 dienogest [Ethinyl Estradiol co-treated with dienogest] results in increased expression of F7 proteinaffects cotreatment|increases expression 15288212
D004317 Doxorubicin [[F3 protein co-treated with F7 protein] results in increased expression of BCL2 protein] which results in decreased susceptibility to Doxorubicinaffects cotreatment|decreases response to substance|increases expression 18325115
C418365 estradiol, norethindrone drug combination estradiol, norethindrone drug combination results in decreased expression of F7 proteindecreases expression 14561536
C454300 estradiol valerate-dienogest [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in increased expression of F7 proteinaffects cotreatment|increases expression 15288212
D004966 Estrogens, Conjugated (USP) Estrogens, Conjugated (USP) results in increased expression of F7 proteinincreases expression 15850603
D004997 Ethinyl Estradiol [Ethinyl Estradiol binds to Norethindrone] which results in increased expression of F7 proteinaffects binding|increases expression 14561536
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with dienogest] results in increased expression of F7 proteinaffects cotreatment|increases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in increased expression of F7 proteinaffects cotreatment|increases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Gestodene] results in increased expression of F7 proteinaffects cotreatment|increases expression 12616980
12618251
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of F7 proteinaffects cotreatment|decreases expression 15157790
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of F7 proteinaffects cotreatment|increases expression 12618251
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of F7 proteinaffects cotreatment|increases expression 12618251
D004997 Ethinyl Estradiol F7 gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Gestodene] results in increased expression of F7 protein]affects cotreatment|affects reaction|increases expression 12616980
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of F7 mRNAaffects expression 17555576
C442659 ethinyl estradiol-desogestrel combination ethinyl estradiol-desogestrel combination results in increased expression of F7 proteinincreases expression 12616980
12618251
C442659 ethinyl estradiol-desogestrel combination F7 gene polymorphism affects the reaction [ethinyl estradiol-desogestrel combination results in increased expression of F7 protein]affects reaction|increases expression 12616980
C056933 fumonisin B1 fumonisin B1 results in decreased expression of F7 mRNAdecreases expression 16221962
C033273 Gestodene [Ethinyl Estradiol co-treated with Gestodene] results in increased expression of F7 proteinaffects cotreatment|increases expression 12616980
12618251
C033273 Gestodene F7 gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Gestodene] results in increased expression of F7 protein]affects cotreatment|affects reaction|increases expression 12616980
D009640 Norethindrone [Ethinyl Estradiol binds to Norethindrone] which results in increased expression of F7 proteinaffects binding|increases expression 14561536
C017576 norgestimate [Ethinyl Estradiol co-treated with norgestimate] results in increased expression of F7 proteinaffects cotreatment|increases expression 12618251
D016912 Levonorgestrel [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of F7 proteinaffects cotreatment|decreases expression 15157790
D016912 Levonorgestrel [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of F7 proteinaffects cotreatment|increases expression 12618251
C516519 NuvaRing NuvaRing results in increased expression of F7 proteinincreases expression 15157790
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of F7 mRNA]affects reaction|increases expression 19555225
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of F7 mRNAdecreases expression 18467677
C023036 perfluorooctanoic acid PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of F7 mRNA]decreases expression|increases reaction 18467677
C006253 pirinixic acid pirinixic acid results in decreased expression of F7 mRNAdecreases expression 16221962
18467677
20059764
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of F7 mRNA]decreases expression|increases reaction 20059764
18467677
D012906 Smoke Smoke results in increased secretion of F7 proteinincreases secretion 17041012
C009277 sodium arsenate sodium arsenate results in decreased expression of F7 mRNAdecreases expression 16882884
D013629 Tamoxifen Tamoxifen affects the expression of F7 mRNAaffects expression 17555576
D014859 Warfarin F7 gene polymorphism affects the susceptibility to Warfarinaffects response to substance 14656880
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3514745880
MESH:D000138 Acidosis Ammonium Chloride 3.3718287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 11.6817505938
MESH:D000152 Acne Vulgaris norgestimate 11.6817505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9418653653
MESH:D000230 Adenocarcinoma Doxorubicin 4.2317418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2314692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.2916434500
MESH:D000419 Albuminuria Doxorubicin 4.3621441931
MESH:D000544 Alzheimer Disease Ozone 2.4015513908
MESH:D000799 Angioedema Acetaminophen 3.6510982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5515885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5115570426
MESH:D001249 Asthma Ozone 2.5817854713 16373670
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 2.9719483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.5114601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.6417150277
MESH:D001943 Breast Neoplasms Doxorubicin 2.3315994142 16935488 18382427 16595493 17983394 15939500 16322301 15634643 17426702 16264153 15993339 18695136 16826403 19526202 17369602 15136595 15692762 18628466 11325840 18234424 15567936 16096432 16115903 15668708
MESH:D001943 Breast Neoplasms Tamoxifen 2.3311161223 17893378 19155303 19288272 19011961 19221464 18629630 19189210 18351453 20544844 20135344 15565566 16202921 19189212 18855134 18815881 19084267 20859285 15668708 19200415 19115204 19244106 16818667 19103187 17049068 21152245 17242785 18984771 16873071 19066611 20390343 17440819 20065188 19410462 20005174 19289846 19487384 18997820 19142967 19059307 18821012 18425577 17261762 21138602 16273361
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5317626835 18315731 19059883 15516495 16777450 18417511 14754758
MESH:D002100 Cachexia Ozone 4.5516183385
MESH:D002276 Carcinoid Tumor Doxorubicin 4.6216051944
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3219066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.403084413
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 4.4018059187 17876044 16023760 16234567
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.4016924424
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.0716201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 2.586189445
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4517572228
MESH:D009202 Cardiomyopathies Doxorubicin 3.4116364871 17007740 17351982 17928571 18627295 16455267 17329180 16612575 17131338 17519947 15505089 17974986 16109756 16952015 16269455 15476868 16731534 17308081 15792986 17382496 16651473 17924179 16278810 16242529 15811867
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8817334414 16243910
MESH:D002386 Cataract Acetaminophen 2.4710977129
MESH:D002543 Cerebral Hemorrhage Warfarin 5.6611061249
MESH:D002779 Cholestasis Ethinyl Estradiol 12.8017110522 16105132 11677210 17681005 15861022 16919318 17333356
MESH:D002779 Cholestasis Levonorgestrel 12.8015861022
MESH:D002779 Cholestasis pirinixic acid 12.8019176532
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.1418802399 18259882
MESH:D023903 Coronary Restenosis Warfarin 5.4912872399
OMIM:122700 COUMARIN RESISTANCE Warfarin 5.6420497562 20579077
MESH:D019465 Craniofacial Abnormalities sodium arsenate 2.7110525206
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1719031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003922 Diabetes Mellitus, Type 1 Warfarin 4.0018772604
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.9219279558
MESH:D003928 Diabetic Nephropathies Warfarin 8.9212644472
MESH:D003875 Drug Eruptions Warfarin 5.7914723717
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.6012540782 15968718 10915739 16781746 12153990 11421492 14550746 14725611 11287661 17522070 17906064 16177239 18071297 19085960 19923254 12958197 12594235 12705907 16081117 19416960 16393943 14986274 10663392 11461765 19164858 16227642 18713872 19739265 11743745 11834606 16485898 11529661 15619225 16109766 11739529 19370779 10774834 17562736 12392966 2444490 19420014
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 8.6017416283
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 8.6016221962
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 8.6018186108
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9119426721
MESH:D004362 Drug Toxicity Doxorubicin 3.5318602426
MESH:D004487 Edema perfluorooctanoic acid 6.4117259670 12083418
MESH:D004487 Edema pirinixic acid 6.4112083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.3312538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.3319031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.1517359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.1519155303 16202921 20544844 17893378
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.9618037988
MESH:D005168 Factor VII Deficiency marker/mechanism
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.0415345470
MESH:D005234 Fatty Liver pirinixic acid 12.0420131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 12.0414986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1216709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3414745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.8019069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.8019069698
MESH:D005756 Gastritis Acetaminophen 3.4816983495
MESH:D006471 Gastrointestinal Hemorrhage Warfarin 6.5211794436
MESH:D005776 Gaucher Disease Warfarin 5.7712359135
MESH:D005909 Glioblastoma Doxorubicin 3.2317150277
MESH:D018149 Glucose Intolerance sodium arsenate 4.9019446573
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.4015692506
MESH:D006331 Heart Diseases Doxorubicin 3.3518006777 16244372 17875725 16330681 16879835 16144979 14766674 16707910 16495754 18674790 17888722 16244371 12587719
MESH:D006333 Heart Failure Doxorubicin 6.6617481944
MESH:D006333 Heart Failure pirinixic acid 6.6620558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.7315692506
MESH:D006406 Hematoma Warfarin 6.5217493413
MESH:D006470 Hemorrhage Warfarin 5.2818429757
MESH:D006474 Hemorrhagic Disorders marker/mechanism 16706976
MESH:D006529 Hepatomegaly fumonisin B1 13.5516221962
MESH:D006529 Hepatomegaly perfluorooctanoic acid 13.553609246
MESH:D006529 Hepatomegaly pirinixic acid 13.5516221962 19772884 19176532 18467677
MESH:D006689 Hodgkin Disease Doxorubicin 3.2518501091 17606976 15147373
MESH:D006930 Hyperalgesia Acetaminophen 7.3616870215
MESH:D006930 Hyperalgesia perfluorooctanoic acid 7.3612083418
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006976 Hypertension, Pulmonary Warfarin 4.6712359135
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6216569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3617937319
MESH:D007249 Inflammation perfluorooctanoic acid 5.0112083418
MESH:D007249 Inflammation Tamoxifen 5.0119457130
MESH:D007333 Insulin Resistance pirinixic acid 2.5116306350
MESH:D007674 Kidney Diseases Acetaminophen 5.7015629191 12587719
MESH:D007674 Kidney Diseases Doxorubicin 5.7015699352 16775033 15369732
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.9816707910
MESH:D007680 Kidney Neoplasms Tamoxifen 2.8918625569
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.9616085563
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.048812269
MESH:D008064 Lipidoses Tamoxifen 3.0217567588 15342952
MESH:D054068 Livedo Reticularis Warfarin 6.5218280355
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 3.3816595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3815474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.3818564211
MESH:D008107 Liver Diseases Acetaminophen 1.5919784758 19460945 16611625 19014921 12587719 12969438 16610002 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0717185352 16871587
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 7.0714757943 18709148
MESH:D008113 Liver Neoplasms pirinixic acid 7.0715890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 7.0716684651
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 2.9017085340 16842330
MESH:D008171 Lung Diseases Ozone 3.258266340 19066396
MESH:D055370 Lung Injury Ozone 3.6620417186
MESH:D008175 Lung Neoplasms Doxorubicin 4.796189445 17418594
MESH:D008175 Lung Neoplasms Ozone 4.798597069 7614698
MESH:D008175 Lung Neoplasms Smoke 4.7911091918
MESH:D008175 Lung Neoplasms Tamoxifen 4.7918625569
MESH:D008223 Lymphoma Doxorubicin 3.3316098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.6317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.3815621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5719428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 5.7415458769
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.7419196723 11731420 16827153 14580682 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.3519453300
MESH:D008545 Melanoma Doxorubicin 3.3016827129
MESH:D008545 Melanoma Tamoxifen 3.3019393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9915990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3819513568
MESH:D008654 Mesothelioma Doxorubicin 2.9817638057
MESH:D008679 Metaplasia Ozone 4.9110496685
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.3215792986
MESH:D052016 Mucositis Doxorubicin 4.6017415656
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.6818186108
MESH:D009203 Myocardial Infarction Doxorubicin 5.4515857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 5.4519151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D009336 Necrosis Warfarin 5.3514723717
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.6218259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.6219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4519410462
MESH:D009369 Neoplasms pirinixic acid 1.8617405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8119196722 19189210 19200415
MESH:D009401 Nephrosis Doxorubicin 4.5816899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.8416889571 15640375
MESH:D009436 Neural Tube Defects sodium arsenate 3.8318186108 19446573 10525206 11749123
MESH:D009447 Neuroblastoma Doxorubicin 3.1715555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7218514411
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.769802331
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D010024 Osteoporosis Levonorgestrel 4.5512665316
MESH:D012516 Osteosarcoma Doxorubicin 3.9615930896
MESH:D010146 Pain Acetaminophen 2.2416870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5111578682
MESH:D010538 Peritonitis Ozone 3.9416369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.9617983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.9617638057
MESH:D011014 Pneumonia Ozone 4.2018381685 18929643 18007984
MESH:D011085 Polycystic Ovary Syndrome ethinyl estradiol-desogestrel combination 5.4317105841
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 4.2017132714
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.4116888761 15897917 16868541 16729912 15749863 18437689
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.4115067354
MESH:D020151 Protein C Deficiency Warfarin 6.1618376272
MESH:D011537 Pruritus Ethinyl Estradiol 9.3615861022 16919318
MESH:D011537 Pruritus Levonorgestrel 9.3615861022
MESH:D011655 Pulmonary Embolism Warfarin 6.1619300499
MESH:D051437 Renal Insufficiency Doxorubicin 4.0317922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D012509 Sarcoma Doxorubicin 3.8216767912 18313854 17203757 15675481 17710206 15625365
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.0616326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6017846226
MESH:D012851 Sinus Thrombosis, Intracranial Warfarin 5.6812269725
MESH:D012878 Skin Neoplasms Doxorubicin 2.8715692506
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.3816767912 15625365 17203757
MESH:D013088 Spermatocele Ethinyl Estradiol 10.9216709447
MESH:D013088 Spermatocele Tamoxifen 10.9216709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8519457130
MESH:D020521 Stroke Warfarin 4.8319300499
MESH:D013923 Thromboembolism Warfarin 5.9716960144 18698879
MESH:D019851 Thrombophilia Ethinyl Estradiol 24.6311994571
MESH:D019851 Thrombophilia ethinyl estradiol-desogestrel combination 24.6311994571
MESH:D019851 Thrombophilia Gestodene 24.6311994571
MESH:D019851 Thrombophilia Warfarin 24.6317493413
MESH:D013927 Thrombosis Ethinyl Estradiol 14.6315669648
MESH:D013927 Thrombosis Gestodene 14.6315669648
MESH:D013927 Thrombosis Warfarin 14.6317245631 19300499 11518727 15720958 11307788 17672075
MESH:D013964 Thyroid Neoplasms Doxorubicin 3.2316010429 17909728
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 4.9617653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 4.9616712894 17572228 8653321
MESH:D014581 Urticaria Acetaminophen 2.8010982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1214692618
MESH:D014657 Vasculitis Warfarin 5.6820337814
MESH:D054556 Venous Thromboembolism Warfarin 6.1718776969
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 23.9015869587 14671159
MESH:D020246 Venous Thrombosis ethinyl estradiol-desogestrel combination 23.9015869587
MESH:D020246 Venous Thrombosis Levonorgestrel 23.9015869587
MESH:D020246 Venous Thrombosis Warfarin 23.9015733061 14723717
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.0317678736 17638931 17334414 16364871
Pathway ID Pathway Name
REACT:24941 Circadian Clock
REACT:24972 Circadian Clock (mouse)
KEGG:04610 Complement and coagulation cascades
REACT:604 Hemostasis
REACT:17015 Metabolism of proteins
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA160
    • No data
    Releated disease ID Related disease Name
    PA443635Cardiovascular Diseases
    PA445848Thromboembolism
    Releated drug ID Related drug Name
    PA451089pravastatin
    PA451906warfarin
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00036 - Coagulation factor VIIa Coagulants;Thrombotic Agents
    DB00100 ligand Coagulation Factor IX Coagulants;Thrombotic Agents
    DB00170 activator Menadione Dietary supplement;Micronutrient;Antifibrinolytic Agents;Vitamins/minerals;Vitamins
    DB03965 - Fucose
    DB04590 - (2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID
    DB04593 - 3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID
    DB04606 - 2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE)
    DB04758 - 2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE)
    DB04767 - N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID
    DB07207 - 2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE
    DB07247 - [2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA
    DB07376 - 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)
    DB08232 - {5-(5-AMINO-1H-PYRROLO[3,2-B]PYRIDIN-2-YL)-6-HYDROXY-3'-NITRO-BIPHENYL-3-YL]-ACETIC ACID
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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