AutismKB 2.0

Annotation Detail for F13A1


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Basic Information Top
Gene Symbol:F13A1 ( F13A )
Gene Full Name: coagulation factor XIII, A1 polypeptide
Band: 6p25.1
Quick LinksEntrez ID:2162; OMIM: 134570; Uniprot ID:F13A_HUMAN; ENSEMBL ID: ENSG00000124491; HGNC ID: 3531
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04610Complement and coagulation cascades
Pathway IDPathway Name
Hemostasis
No data
No data
Pathway IDPathway Name
500303Common Pathway
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1819Malignant childhood tumor
1858Hemorrhagic disorder
1914Cerebrovascular disorder
1918Atherosclerosis
1964Primary biliary cirrhosis
1998Enteritis
2009Sarcoma
2012Pulmonary embolism
2051Leukemia
2068Skin disease
Desease Name
nonfatal myocardial infarction.
thrombosis, venous
Atrial Fibrillation
Thrombosis
CARDIOVASCULAR
myocardial infarct
subconjunctival hemorrhage
Alzheimer's disease
stroke, ischemic
brain hemorrhage
intracranial hemorrhage
IMMUNE
NEUROLOGICAL
white matter disease
varicose ulcers
pregnancy loss, recurrent
Stroke
Myocardial Infarction
antiphospholipid syndrome
REPRODUCTION
hemorrhage, intracerebral
coagulation disorder
No data
Desease Name
Factor XIIIA deficiency
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of F13A1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of F13A1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of F13A1 mRNAincreases expression 20458559
D004041 Dietary Fats Dietary Fats results in decreased expression of F13A1 mRNAdecreases expression 18042831
D004958 Estradiol Estradiol affects the expression of F13A1 mRNAaffects expression 14699072
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of F13A1 mRNAaffects cotreatment|decreases expression 17404688
D007460 Iodoacetamide Iodoacetamide results in decreased activity of F13A1 proteindecreases activity 15618543
D007501 Iron Iron deficiency results in decreased expression of F13A1 mRNAdecreases expression 20368581
D015735 Mifepristone Mifepristone results in increased expression of F13A1 mRNAincreases expression 17584828
C029938 nickel sulfate nickel sulfate results in decreased expression of F13A1 mRNAdecreases expression 16780908
C041786 palm oil palm oil results in decreased expression of F13A1 mRNAdecreases expression 18042831
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of F13A1 mRNAaffects cotreatment|decreases expression 17404688
D020849 Raloxifene Raloxifene affects the expression of F13A1 mRNAaffects expression 14699072
D013629 Tamoxifen ESR2 protein affects the reaction [Tamoxifen results in decreased expression of F13A1 mRNA]affects reaction|decreases expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of F13A1 mRNAaffects expression 14699072
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of F13A1 mRNAdecreases expression 18495758
17884332
16443690
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of F13A1 mRNAincreases expression 17884332
D014807 Vitamin D Vitamin D affects the expression of F13A1 mRNAaffects expression 20368581
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6114745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9015322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.6118287403
MESH:D055371 Acute Lung Injury nickel sulfate 4.3419131640 16100012 12718980 11954676
MESH:D000230 Adenocarcinoma arsenic trioxide 4.4219825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 4.4211473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4316835633
MESH:D000419 Albuminuria Raloxifene 4.6317308373 17451421
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.7016640825
MESH:D000544 Alzheimer Disease Iron 4.6016640825 16563566
MESH:D000544 Alzheimer Disease Raloxifene 4.6015800139
MESH:D000740 Anemia Iron 9.0116434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 9.0111748828
MESH:D018798 Anemia, Iron-Deficiency Iron 4.6716569441 17162259 17375513 17147795 17163184
MESH:D000756 Anemia, Sideroblastic Iron 4.8416910769
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D001145 Arrhythmias, Cardiac Iron 4.4016604332
MESH:D001161 Arteriosclerosis Dietary Fats 3.9315238619
MESH:D001260 Ataxia Telangiectasia Iron 5.5015336622
MESH:D050197 Atherosclerosis Iron 3.7216640825 16632123
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Iron 2.1417352947
MESH:D001424 Bacterial Infections Iron 5.2416640825
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 9.0616206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.0612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.4017868700
MESH:D001930 Brain Injuries Progesterone 11.1115380490 15665606 15845082
MESH:D001930 Brain Injuries Raloxifene 11.1116580743
MESH:D001943 Breast Neoplasms Dietary Fats 2.9720435547
MESH:D001943 Breast Neoplasms Estradiol 2.9717261762 12948864 18497071 17289903 19861407 17018787 16675129 14630087
MESH:D001943 Breast Neoplasms Progesterone 2.9717614352 15562024 16175315
MESH:D001943 Breast Neoplasms Raloxifene 2.9717242785 17952589 15775269 16912660 16837676 15758505 17595753 17893378 17440819 17261762 17049068 15572757
MESH:D001943 Breast Neoplasms Tamoxifen 2.9718855134 21152245 16202921 17049068 11161223 19189210 19011961 19084267 17893378 18821012 19115204 19410462 19142967 17242785 18629630 16873071 20135344 19244106 15668708 19059307 15565566 19487384 19221464 17440819 20544844 20005174 18815881 18984771 18425577 19066611 18351453 16818667 19155303 19103187 19289846 19200415 18997820 17261762 16273361 19189212 19288272 20065188 21138602 20390343 20859285
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9720435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3611589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5116111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5519066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.593084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.5911135700 16217749 15553829 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.5916924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.5916924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1412490120
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.5917572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.5917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 18670907 16120746
MESH:D009202 Cardiomyopathies Iron 4.0616640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.4716604332
MESH:D002318 Cardiovascular Diseases Raloxifene 3.4615775269
MESH:D002386 Cataract Acetaminophen 2.6010977129
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.7918566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1116354765 12621046 8697196 15340226 15668235
MESH:D003072 Cognition Disorders Raloxifene 4.6615800139
MESH:D003110 Colonic Neoplasms Iron 2.8916640825
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4810048152 15322242 20055451
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.1315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4019031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.1917474826
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.7111298694 16780908 16823706
MESH:D003920 Diabetes Mellitus Iron 4.4816604332 16640825
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.3616506275
MESH:D003924 Diabetes Mellitus, Type 2 Iron 4.5716506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.5717107852
MESH:D003928 Diabetic Nephropathies Estradiol 15.1719279558
MESH:D003928 Diabetic Nephropathies Raloxifene 15.1717308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 15.1719279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.5317187935
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.5817906064 15619225 12705907 19164858 15968718 11743745 17522070 19420014 11421492 16485898 14725611 12540782 16781746 16393943 18071297 10663392 11461765 18713872 19416960 19370779 12958197 19739265 16109766 12392966 19085960 14550746 10774834 11529661 14986274 19923254 11834606 12153990 16227642 17562736 16081117 10915739 16177239 11739529 12594235 2444490 11287661
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.5820420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4718367378
MESH:D004487 Edema Raloxifene 6.9515860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.9512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9615322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 15.6617692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.6615845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.6619031437
MESH:D016889 Endometrial Neoplasms Estradiol 7.4518566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.4516202921 19155303 17893378 20544844
MESH:D004715 Endometriosis Mifepristone 15.5016134523
MESH:D004715 Endometriosis Progesterone 15.5016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 15.509294722 10568697
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3212903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005177 Factor XIII Deficiency marker/mechanism
MESH:D005234 Fatty Liver arsenic trioxide 25.0315073043
MESH:D005234 Fatty Liver Dietary Fats 25.0318296743 17967931 19004024 19551842
MESH:D005234 Fatty Liver Iron 25.0316640825
MESH:D005234 Fatty Liver Raloxifene 25.0317473493
MESH:D005234 Fatty Liver Tamoxifen 25.0314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2319069698
MESH:D005355 Fibrosis Dietary Fats 8.7618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.7620067830
MESH:D005621 Friedreich Ataxia Iron 5.4716604332 16640825
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3016904648
MESH:D005756 Gastritis Acetaminophen 11.9316983495
MESH:D005756 Gastritis Iodoacetamide 11.9315046732
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3411294989 10048152
MESH:D006331 Heart Diseases Raloxifene 3.5511110106
MESH:D006432 Hemochromatosis Iron 4.5116604332 17236123 17255318 17053826 16574947 16640825
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006486 Hemosiderosis Iron 5.2816604332
MESH:D006525 Hepatitis, Viral, Human Iron 5.5316640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.9817182432
MESH:D006529 Hepatomegaly Iron 8.8916890145
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.8916120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 5.0915709030
MESH:D015658 HIV Infections Iron 3.6816597321
MESH:D019584 Hot Flashes Estradiol 3.8117088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1116959395 18606429 8697196 16354765 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.7216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6221332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.6521332399
MESH:D006973 Hypertension Raloxifene 5.2615787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2618850075 18670907
MESH:D007006 Hypogonadism Iron 4.4216640825
MESH:D007037 Hypothyroidism Iron 5.1216640825
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.4415869954
MESH:D007249 Inflammation Dietary Fats 12.0820412841
MESH:D007249 Inflammation Progesterone 12.0815869954
MESH:D007249 Inflammation Tamoxifen 12.0819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.0812878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 7.4318457598 11836018
MESH:D007333 Insulin Resistance Estradiol 7.4316393666 16627594
MESH:D019189 Iron Metabolism Disorders Iron 5.0717163184
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007674 Kidney Diseases Acetaminophen 5.9415629191 12587719
MESH:D007674 Kidney Diseases Estradiol 5.9415618244
MESH:D007680 Kidney Neoplasms Estradiol 7.4615610895
MESH:D007680 Kidney Neoplasms Tamoxifen 7.4618625569
MESH:D007889 Leiomyoma Raloxifene 4.5316973256
MESH:D007938 Leukemia arsenic trioxide 2.8415070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.5316467208 16968895 17050201 20471514 19850784
MESH:D015470 Leukemia, Myeloid, Acute Vitamin D 4.5320368581
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.2316823087 17649720 17107899 12679006 17712046 12018890 11468182 16330433 19642359 15622746 19075265 15213294 16112521 16891316 12712474 16966277 16331271 11161223 19035177 17217047 15748426 15336539 9834237 17869043 19225113
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3916882451
MESH:D020961 Lewy Body Disease Iron 5.4716563566
MESH:D008064 Lipidoses Tamoxifen 3.1715342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 7.0218296743
MESH:D008103 Liver Cirrhosis Iron 7.0216640825
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4512878042
MESH:D008107 Liver Diseases Acetaminophen 1.6319460945 16611625 19784758 12587719 19014921 11587558 12969438 16610002
MESH:D008108 Liver Diseases, Alcoholic Iron 5.0516737972 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2617185352 16871587
MESH:D008113 Liver Neoplasms arsenic trioxide 10.8314682389
MESH:D008113 Liver Neoplasms Iron 10.8316640825 20302851
MESH:D008113 Liver Neoplasms Tamoxifen 10.8316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.8316984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 5.8620377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3715213294
MESH:D008175 Lung Neoplasms arsenic trioxide 4.9019825857 11798837
MESH:D008175 Lung Neoplasms Iron 4.9016640825
MESH:D008175 Lung Neoplasms Tamoxifen 4.9018625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.9019555203 11884234
MESH:D008268 Macular Degeneration Iron 3.9916640825
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8119428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.0817203775 11408345 16891317 11807958
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 10.0811408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.0811731420 14580682 16827153 19196722 19196723
MESH:D020149 Manganese Poisoning Estradiol 12.8619453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.8619453300
MESH:D008545 Melanoma Tamoxifen 1.8812393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6119513568
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.6215863610
MESH:D009101 Multiple Myeloma arsenic trioxide 7.4819417148 15949261 19549372 14977855 11468182
MESH:D009101 Multiple Myeloma Raloxifene 7.4816497877
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.7317086897
MESH:D009181 Mycoses Iron 5.5316640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1616105982 16882451
MESH:D017202 Myocardial Ischemia Iron 9.2416604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.2412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.8116810080
MESH:D015428 Myocardial Reperfusion Injury Iron 8.8116604332
MESH:D009232 Myxoma Raloxifene 5.6216343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0016624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0619189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7817289903
MESH:D009404 Nephrotic Syndrome Iron 4.5417178036
MESH:D009421 Nervous System Malformations Estradiol 9.5916427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.5914600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.1310525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.5918514411
MESH:D019636 Neurodegenerative Diseases Iron 8.5916604332 17296847
MESH:D009765 Obesity Dietary Fats 2.2916723640 21332399 18457598 17217161 19632207 20518802 20132043 18674790 11836018
MESH:D010003 Osteoarthritis Iron 3.9816640825
MESH:D010024 Osteoporosis Iron 12.3116640825 16648989
MESH:D010024 Osteoporosis Raloxifene 12.3117882678 15775268 19059307
MESH:D010024 Osteoporosis Vitamin D 12.3117882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.2617893378 15758505 15579764 17823083
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.4116624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 11.4119401270
MESH:D010051 Ovarian Neoplasms Mifepristone 11.4116525653
MESH:D010051 Ovarian Neoplasms Progesterone 11.4117393432 16525653
MESH:D010146 Pain Acetaminophen 2.4116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5315580305
MESH:D010212 Papilloma Iron 4.5212065085
MESH:D010235 Paraganglioma arsenic trioxide 4.1919927285
MESH:D020447 Parasomnias Iron 6.0817352947
MESH:D010300 Parkinson Disease Iron 3.3316563566 16640825
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010900 Pituitary Diseases Iron 5.7316604332
MESH:D011041 Poisoning Iron 4.3216604332
MESH:D017119 Porphyria Cutanea Tarda Iron 11.1416640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 11.1418163543
MESH:D011225 Pre-Eclampsia Iron 4.4416640825
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411399792 11896295 11118676 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0819131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.0816740699
MESH:D011471 Prostatic Neoplasms Raloxifene 2.0816536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0815067354
MESH:D011528 Protozoan Infections Iron 6.0816640825
MESH:D011693 Purpura Raloxifene 5.6215770314
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012148 Restless Legs Syndrome Iron 4.5716930377
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8618045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0016646077
MESH:D012878 Skin Neoplasms Iron 5.9212065085
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.9216192470
MESH:D013088 Spermatocele Tamoxifen 4.3516709447
MESH:D013119 Spinal Cord Injuries Progesterone 11.0415862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 11.0419457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D020521 Stroke Raloxifene 3.8416837676
MESH:D013398 Sudden Infant Death Iron 5.5016640825
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.1119014326
MESH:D013978 Tibial Fractures Estradiol 13.9219048282
MESH:D013978 Tibial Fractures Raloxifene 13.9219048282
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0115213294
MESH:D014376 Tuberculosis Iron 4.1016597321
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.4511780464 12973940 12845720 20435036
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 8.4517572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.458653321 16712894 17572228
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.2716837676
MESH:D014846 Vulvar Neoplasms Raloxifene 5.6216343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D015430 Weight Gain Dietary Fats 3.7616723640
Pathway ID Pathway Name
KEGG:04610 Complement and coagulation cascades
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00130 - L-Glutamine Dietary supplement;Micronutrient;Non-Essential Amino Acids
DB01839 - 1,2-Propanediol Solvents;Vehicles
DB02340 - N-Acetyl-Serine
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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