AutismKB 2.0

Annotation Detail for FABP7


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Basic Information Top
Gene Symbol:FABP7 ( B-FABP,BLBP,DKFZp547J2313,FABPB,MRG )
Gene Full Name: fatty acid binding protein 7, brain
Band: 6q22.31
Quick LinksEntrez ID:2173; OMIM: 602965; Uniprot ID:FABP7_HUMAN; ENSEMBL ID: ENSG00000164434; HGNC ID: 3562
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03320PPAR signaling pathway
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1766Renal Cell cancer
1860Brain tumor
1983Down syndrome
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of FABP7 mRNAincreases expression 12576510
D000082 Acetaminophen Acetaminophen affects the expression of FABP7 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FABP7 mRNAaffects expression 16483693
C032036 bromobenzene bromobenzene metabolite binds to FABP7 proteinaffects binding 17305373
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FABP7 mRNAaffects cotreatment|decreases expression 20360939
D002995 Clofibric Acid Clofibric Acid affects the expression of FABP7 mRNAaffects expression 17602206
D003314 Corn Oil Corn Oil affects the expression of FABP7 mRNAaffects expression 16360708
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FABP7 mRNAaffects cotreatment|decreases expression 20360939
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of FABP7 mRNAdecreases expression 17072980
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of FABP7 mRNAincreases expression 12072388
D008628 Mercury Mercury results in increased expression of FABP7 mRNAincreases expression 16823088
C059514 resveratrol resveratrol results in increased expression of FABP7 mRNAincreases expression 12002526
D013752 Tetracycline Tetracycline results in decreased expression of FABP7 mRNAdecreases expression 16917069
D014212 Tretinoin Tretinoin results in increased expression of FABP7 mRNAincreases expression 17045167
D014212 Tretinoin NEUROD2 protein affects the reaction [Tretinoin results in increased expression of FABP7 mRNA]affects reaction|increases expression 16083855
D014212 Tretinoin Tretinoin results in increased expression of FABP7 mRNAincreases expression 16083855
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D058186 Acute Kidney Injury resveratrol 3.9016538975
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 4.5516033868
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.5514692618
MESH:D000236 Adenoma Diethylnitrosamine 11.516695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 11.5119555203
MESH:D000236 Adenoma resveratrol 11.5115688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.9817620307 17162532 19061943 18056438 19052882 16434500
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000544 Alzheimer Disease resveratrol 2.5816162502 16183991
MESH:D000799 Angioedema Acetaminophen 3.9410982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 12.4715885639
MESH:D001169 Arthritis, Experimental resveratrol 12.4717115116
MESH:D001169 Arthritis, Experimental Tretinoin 12.4716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D050197 Atherosclerosis resveratrol 3.3017967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Mercury 2.1417497416
MESH:D001327 Autoimmune Diseases Mercury 4.9416634805
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.6616206674 16197459
MESH:D002545 Brain Ischemia resveratrol 4.3717600658
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9617474063
MESH:D001943 Breast Neoplasms resveratrol 1.9616393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tretinoin 1.9616873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002277 Carcinoma Dimethylnitrosamine 4.0619555203
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.653084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.6520524982 16878318 20084675 16830150 18785209 18506893 17761372 18788625 19519916 19052882 19394651 18210153 16807293 17055752 20935162 17138121 17428255 17978847 19107877 20214788 19383236 19208518 10737359 19171122 18665156 16540662 18978308 19919837 20512989 16328049 19418558 18393292 3581430 19701751 19335982 20727157 21159647 19539802 18971187 16288022 16779866 16502159 11831363 16935385 18494052 3084413 20432363 17173139 20007298 16698587 16681979 20514400 18691550 16569478 18056438 10672840 20101231 19822196 17162532
MESH:D006528 Carcinoma, Hepatocellular resveratrol 6.6516227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.651917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.6716675471
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 7.7716033868
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.7716227395
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.7716096774 16051514
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.4710334427
MESH:D002318 Cardiovascular Diseases resveratrol 3.5115458977
MESH:D002386 Cataract Acetaminophen 7.3310977129
MESH:D002386 Cataract Tretinoin 7.3317460283
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 2.8917174075 21159647 7505956 2727394
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.7319052882
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9117681005 16105132 16919318 15861022 17333356 17110522 11677210
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002972 Cleft Palate Tretinoin 2.699407595
MESH:D003092 Colitis resveratrol 9.8716474422
MESH:D003092 Colitis Tretinoin 9.8717035595
MESH:D003110 Colonic Neoplasms resveratrol 2.4616338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2216550006
MESH:D003327 Coronary Disease resveratrol 3.7816507316
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.8210589399 9125849 16925845 9664655 17551590 14991402 9224671 8800419 9211117 9142499
MESH:D017449 Dermatitis, Allergic Contact Mercury 3.8616823706
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.8116873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2020387270
MESH:D003928 Diabetic Nephropathies resveratrol 4.0116286809
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.2311529661 18071297 10663392 11461765 18713872 16227642 17906064 19416960 11743745 11834606 2444490 16109766 12540782 14986274 19420014 19739265 15619225 12958197 12594235 16177239 12153990 12705907 10774834 19085960 19923254 11287661 11739529 16781746 14550746 14725611 19164858 16081117 16393943 10915739 15968718 11421492 12392966 17522070 16485898 17562736 19370779
MESH:D056486 Drug-Induced Liver Injury bromobenzene 12.2312628495 10092053
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.2319107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 12.238172417
MESH:D056486 Drug-Induced Liver Injury Tetracycline 12.2317522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1919426721
MESH:D004487 Edema resveratrol 3.428985016
MESH:D004489 Edema, Cardiac Tretinoin 4.5618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.3412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 9.3417872969
MESH:D016889 Endometrial Neoplasms Tretinoin 3.1416569247
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.9217923197
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2116302075
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 2.9217016578
MESH:D005124 Eye Abnormalities Tretinoin 3.629664655 16938888
MESH:D005234 Fatty Liver Diethylnitrosamine 13.5421071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.5415345470
MESH:D005234 Fatty Liver Tetracycline 13.5419224547 16917069
MESH:D005355 Fibrosis Tretinoin 3.5817994277
MESH:D005756 Gastritis Acetaminophen 3.7716983495
MESH:D005909 Glioblastoma Tretinoin 3.0417312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.929664655 14991402
MESH:D006561 Herpes Simplex resveratrol 4.2616876885
MESH:D006930 Hyperalgesia Acetaminophen 7.7716870215
MESH:D006930 Hyperalgesia Tretinoin 7.7716870215
MESH:D006937 Hypercholesterolemia resveratrol 4.0617188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D006949 Hyperlipidemias resveratrol 4.0916873680
MESH:D006968 Hypersensitivity, Delayed Corn Oil 5.9111484837
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.3517488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.7217600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5217937319
MESH:D007249 Inflammation Diethylnitrosamine 5.3518785209
MESH:D007249 Inflammation resveratrol 5.3516366677
MESH:D007251 Influenza, Human resveratrol 4.6416624496
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.6410783313
MESH:D007569 Jaw Abnormalities Tretinoin 3.9517551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 10.4515629191 12587719
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 10.4515369732
MESH:D007674 Kidney Diseases Mercury 10.4517934191
MESH:D007938 Leukemia Tretinoin 2.7917143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7519285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0816294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 13.0916766008
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 13.0916087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 13.0917107899 16331271 17339181 17368321 17712046 15748426 19642359 19029980 17361223 17217047 16823087 16935935 17294898 19225113 19035177 16140955 9834237 17506722 17649720 16766008 16891316 12679006 16788101 17301526 19075265
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8520032147 18665156 18522880 19638242 18407596
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 17072980
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 2.7715138612 16570917 17666798 17198567 14568256 14643895 17348192 15383259 15479170 16169303 17640959 14726149 15067225 18567088 15733078 15591649 12918455 17203207 15366600 18239293 15571005 15723089 15492853 15369754 18672772 16627068 15942678 15161499 16544323 17201889 17724770 15577212 17719030 18637143 14709902 16603200 16042886 14659978 18210741 17881167 17432682 15504291 17036385 15793283 18237412 17534399 17196135 15744066 15298665 15798949 17465448 18629640 18371158 12925901 15086199 15081153 16009107 15339415 18364076 15864749 15763062 15842777 16270385 15099470 18095165
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.7718397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 3.9512969438 16611625 19014921 11587558 19460945 19784758 16610002 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9517034775
MESH:D017114 Liver Failure, Acute Acetaminophen 9.8417185352 16871587
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 9.8417457977
MESH:D008113 Liver Neoplasms Clofibric Acid 10.9617602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 10.9618977376 18978307 19996281 20118626 18644402 19850985 20101389 19833225 18648771 2862719 19638242 20434301 12112319 21071580 19254457 19551842 19255062 21167192 12771043 2422723 19294768 19427195 19426721 20583210 21278145 19642983 19499222 19073162 20137499 19090486 18754104 16942905 15175105 21047994 19690152 15885732 19812893 20501860 19256749 20492335 20452335 20405173 9163691 10737359
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 10.9615890375 3113478
MESH:D008113 Liver Neoplasms resveratrol 10.9619073162 19812893 19321006 20405173
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.3219009564 17174075 16267830 17854601 18282651 2563599 19539802 18308698 19519916 16842330 18079962 18093689 18775883 9362446 17942915 19004024 18164116 3124819 18544905 19126423 18253720 21159647
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 6.3215603536 6150874 1848544
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.7220970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 2.7216061637 19555203 11884234
MESH:D016393 Lymphoma, B-Cell resveratrol 4.3617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.9114749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.3315688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 3.148985016 11606380
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma resveratrol 3.4917992120
MESH:D008545 Melanoma Tretinoin 3.4916752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6419513568
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D008659 Metabolic Diseases resveratrol 4.4317112576
MESH:D009101 Multiple Myeloma resveratrol 3.5016267019 16490592 17164350 14749477 17049120 17935668
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.9517962980
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1117596541
MESH:D009203 Myocardial Infarction resveratrol 3.0516525036 16317513 17125593 17188708 16456233 17015251
MESH:D017202 Myocardial Ischemia resveratrol 4.0517015251 17125593
MESH:D009205 Myocarditis resveratrol 4.8417322642
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.593581430 9029167
MESH:D009369 Neoplasms Tretinoin 2.4316594593 16946489
MESH:D009374 Neoplasms, Experimental resveratrol 4.078985016
MESH:D009395 Nephritis, Interstitial Tetracycline 4.889884423
MESH:D009421 Nervous System Malformations Tretinoin 3.849125849
MESH:D009436 Neural Tube Defects Tretinoin 3.099142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 14.3318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 14.3320387270
MESH:D019636 Neurodegenerative Diseases resveratrol 14.3317652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.4617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2120387270
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.3117513867
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3616936753
MESH:D010146 Pain Acetaminophen 6.7416870215
MESH:D010146 Pain Tretinoin 6.7416870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.3116540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.3115976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010391 Pemphigoid, Bullous Tetracycline 5.5311026799
MESH:D011230 Precancerous Conditions Corn Oil 9.7814668109
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.782563599
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 4.2616679765
MESH:D017096 Prion Diseases Tetracycline 5.4910903871
MESH:D011471 Prostatic Neoplasms resveratrol 3.6317804756 17675339 17636462 15767336 16731767 17718901
MESH:D011507 Proteinuria Tretinoin 3.6616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3915861022 16919318
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.6816325855
MESH:D015427 Reperfusion Injury resveratrol 3.3017520802 16317513 16314181 17058453 15827377
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616116481 16283617
MESH:D012878 Skin Neoplasms resveratrol 6.008985016 15837718
MESH:D012878 Skin Neoplasms Tretinoin 6.0016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0416709447
MESH:D013158 Splenic Diseases Dimethylnitrosamine 5.3712587719
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4718456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 3.4716033868
MESH:D013274 Stomach Neoplasms Tretinoin 3.4717261132
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.5316321402
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.317505956
MESH:D013964 Thyroid Neoplasms Tretinoin 7.3116026305 17045167
MESH:D014062 Tongue Neoplasms resveratrol 10.0816227395
MESH:D014062 Tongue Neoplasms Tretinoin 10.0816051514
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D014581 Urticaria Acetaminophen 3.0310982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 9.7017473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.7016129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.7214692618
MESH:D014594 Uterine Neoplasms resveratrol 9.7217044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5914671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.3717488730
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
Pathway ID Pathway Name
KEGG:03320 PPAR signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top
No data
No data
No data
Drugbank ID Action Drug Name Description
DB00132 - Alpha-Linolenic Acid Dietary supplement;Micronutrient
DB00154 - gamma-Homolinolenic acid Dietary supplement;Micronutrient
DB00159 - Icosapent Dietary supplement;Micronutrient
DB03756 - Docosa-4,7,10,13,16,19-Hexaenoic Acid
DB04224 - Oleic Acid

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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