AutismKB 2.0

Annotation Detail for FBLN2


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Basic Information Top
Gene Symbol:FBLN2 ( - )
Gene Full Name: fibulin 2
Band: 3p25.1
Quick LinksEntrez ID:2199; OMIM: 135821; Uniprot ID:FBLN2_HUMAN; ENSEMBL ID: ENSG00000163520; HGNC ID: 3601
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FBLN2 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLN2 mRNAaffects cotreatment|increases expression 18164116
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of FBLN2 mRNAincreases expression 17484886
D003345 Corticosterone Corticosterone results in decreased expression of FBLN2 mRNAdecreases expression 15755911
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA]decreases reaction|increases expression 18200517
D004041 Dietary Fats Dietary Fats results in increased expression of FBLN2 mRNAincreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLN2 mRNAaffects cotreatment|increases expression 18164116
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of FBLN2 mRNAincreases expression 14664709
D004958 Estradiol Estradiol results in increased expression of FBLN2 mRNAincreases expression 14664709
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of FBLN2 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of FBLN2 mRNAincreases expression 16467188
17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FBLN2 mRNAaffects cotreatment|increases expression 17942748
C041786 palm oil palm oil results in increased expression of FBLN2 mRNAincreases expression 18042831
C084656 paricalcitol [Phosphorus co-treated with paricalcitol] results in increased expression of FBLN2 mRNAaffects cotreatment|increases expression 17715259
D010758 Phosphorus [Phosphorus co-treated with paricalcitol] results in increased expression of FBLN2 mRNAaffects cotreatment|increases expression 17715259
D011374 Progesterone Progesterone results in increased expression of FBLN2 mRNAincreases expression 17404688
D011794 Quercetin Quercetin results in increased expression of FBLN2 mRNAincreases expression 15309432
D013629 Tamoxifen Tamoxifen affects the expression of FBLN2 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FBLN2 mRNAaffects cotreatment|increases expression 17942748
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA]decreases reaction|increases expression 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNAincreases expression 18200517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8115322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.5218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D000230 Adenocarcinoma Estradiol 4.1811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1814692618
MESH:D000236 Adenoma beta-Naphthoflavone 6.8019389873
MESH:D000236 Adenoma Diethylnitrosamine 6.8010737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.9416434500 19061943 17162532 17620307 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.9416835633
MESH:D019973 Alcohol-Related Disorders Curcumin 5.0517887948
MESH:D000544 Alzheimer Disease Curcumin 2.6115590663
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4415469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.2017084956
MESH:D001161 Arteriosclerosis Dietary Fats 9.7815238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.7811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6415885639
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.7316807698
MESH:D001260 Ataxia Telangiectasia Quercetin 4.9415336622
MESH:D050197 Atherosclerosis Curcumin 3.2918704882
MESH:D001327 Autoimmune Diseases Curcumin 10.7419761891
MESH:D001327 Autoimmune Diseases Quercetin 10.7419761891
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.3117868700
MESH:D001930 Brain Injuries Progesterone 4.2215665606 15380490 15845082
MESH:D002545 Brain Ischemia Curcumin 4.2916770732
MESH:D001932 Brain Neoplasms Curcumin 3.9017596214
MESH:D001943 Breast Neoplasms Curcumin 5.8018593918 19250217 16243823 18462866
MESH:D001943 Breast Neoplasms Dietary Fats 5.8020435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.8017474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 5.8017129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 5.8017289903 19861407 12948864 17018787 16675129 14630087 17261762 18497071
MESH:D001943 Breast Neoplasms Progesterone 5.8017614352 15562024 16175315
MESH:D001943 Breast Neoplasms Quercetin 5.8018628248
MESH:D001943 Breast Neoplasms Tamoxifen 5.8020135344 18984771 18855134 19289846 19221464 17242785 18351453 17440819 18629630 18425577 17893378 19244106 18815881 17049068 19084267 19155303 19142967 19487384 15668708 19103187 11161223 20859285 19011961 19059307 16202921 17261762 19115204 20065188 20544844 19066611 15565566 16818667 21138602 21152245 19189210 16273361 19410462 18997820 16873071 19200415 19189212 20390343 19288272 20005174 18821012
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.8020435547
MESH:D002105 Cadmium Poisoning Quercetin 5.5216962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4316111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7416192424 15700767 16050911 16227642 16011737 15673190 18705752 15721981 3786805 10355542 16097048 16124888
MESH:D002277 Carcinoma Curcumin 8.1618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.1616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4719066611
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.3118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.3120512989 16569478 19919837 16935385 19383236 19208518 17162532 10672840 18978308 20727157 16878318 17138121 18494052 20214788 19107877 20514400 20101231 16502159 20084675 19701751 18971187 18210153 16698587 19171122 16540662 17761372 20524982 17173139 17428255 18506893 18665156 19822196 16681979 19539802 20935162 16328049 18691550 18788625 20432363 18393292 10737359 3084413 16830150 11831363 20007298 19052882 18785209 17055752 19418558 21159647 16807293 16288022 18056438 16779866 19519916 17978847 3581430 19335982 19394651
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 11.3116924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.3116924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 11.3119519916 12508355
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.3116924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.9618414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.9217234771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 2.7518462866
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5717572228
MESH:D006332 Cardiomegaly Quercetin 6.7219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.7218670907 18850075 16120746
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.597505956 2727394 21159647 17174075
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.5918566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2016835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8411677210 16105132 15861022 17681005 17110522 16919318 17333356
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0816354765 15668235 8697196 12621046 15340226
MESH:D003092 Colitis Curcumin 9.8216782535 16804969 18200517
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 9.8211698051 16474422 16782535 17991707 16804969 17936198 18200517 18023891 16867261
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.4317276891
MESH:D003103 Coloboma Curcumin 4.5118809619
MESH:D003110 Colonic Neoplasms Curcumin 3.9716340194 19359593
MESH:D003110 Colonic Neoplasms Quercetin 3.9719440933 11134977 17191121 16640504 17148506 15741050 19056647
MESH:D015179 Colorectal Neoplasms marker/mechanism 17892325
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818095365 18852136
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0217141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.8618497527
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 20055451 15322242
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.5216002989 12952375
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3219031437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6919496084
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 7.0718403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.0720387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.0717107852
MESH:D003928 Diabetic Nephropathies Curcumin 14.8118204486
MESH:D003928 Diabetic Nephropathies Estradiol 14.8119279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 14.8119279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.4517187935
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.1115968718 21278145 17522070 3786805 4309450 11566570 9327722 10915739 2869522 6884620 7440962 7120509 16177239 3732212 16227642 15027814 19085960 19336974 7179309 6623471 15998439 10092053
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.1119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.1120420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D004381 Duodenal Ulcer Curcumin 4.0117351913
MESH:D050171 Dyslipidemias Dietary Fats 3.4218367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8716714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.0912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 15.0917692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.0919031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.6616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 12.3116804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 12.3111473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 12.3119155303 17893378 16202921 20544844
MESH:D004715 Endometriosis Progesterone 8.8016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.8010568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0916302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 30.2312631006 16045604 15959796 12795759 16239168 19224547 61145 17595544
MESH:D005234 Fatty Liver Curcumin 30.2319297423
MESH:D005234 Fatty Liver Dietary Fats 30.2317967931 18296743 19004024 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 30.2321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.2315345470
MESH:D005234 Fatty Liver Tamoxifen 30.2319224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 8.1216002989 16513791 15751030 16611131 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 8.1216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1519069698
MESH:D005355 Fibrosis Carbon Tetrachloride 34.0918705752
MESH:D005355 Fibrosis Curcumin 34.0918705752
MESH:D005355 Fibrosis Dietary Fats 34.0918296743
MESH:D005355 Fibrosis Quercetin 34.0919474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 34.0920067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 34.0917994277
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.6518462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.9116452187
MESH:D005909 Glioblastoma Curcumin 7.3317596214
MESH:D005909 Glioblastoma Quercetin 7.3319804834
MESH:D005910 Glioma Quercetin 3.0417643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006258 Head and Neck Neoplasms Curcumin 3.6318829502 18462866
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3111294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5519900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8512621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.0017701891
MESH:D006558 Herpes Genitalis Estradiol 5.0015709030
MESH:D019584 Hot Flashes Estradiol 3.7217088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0215340226 16354765 8697196 16959395 18606429
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5016899240
MESH:D006937 Hypercholesterolemia Curcumin 9.1018704882
MESH:D006937 Hypercholesterolemia Dietary Fats 9.1021332399
MESH:D006943 Hyperglycemia Quercetin 3.9918262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 3.5721332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.4012960047 14722030
MESH:D006973 Hypertension Quercetin 5.1718356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1718850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0515338365
MESH:D007021 Hypospadias Diethylstilbestrol 11.1116002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.1116945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.3615869954
MESH:D007246 Infertility Diethylstilbestrol 4.3115036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4617937319
MESH:D007249 Inflammation Curcumin 19.6917151092 18403477 16956363
MESH:D007249 Inflammation Dietary Fats 19.6920412841
MESH:D007249 Inflammation Diethylnitrosamine 19.6918785209
MESH:D007249 Inflammation Progesterone 19.6915869954
MESH:D007249 Inflammation Tamoxifen 19.6919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 19.6912878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.6318200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 6.6318200517
MESH:D007251 Influenza, Human Quercetin 4.4816624496
MESH:D007333 Insulin Resistance Dietary Fats 7.2718457598 11836018
MESH:D007333 Insulin Resistance Estradiol 7.2716393666 16627594
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 4.5717994277
MESH:D007414 Intestinal Neoplasms Curcumin 4.1810783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007627 Keloid Quercetin 4.9217086741
MESH:D007674 Kidney Diseases Estradiol 6.1315618244
MESH:D007674 Kidney Diseases Quercetin 6.1316962696
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 12.2615003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 12.2615610895
MESH:D007680 Kidney Neoplasms Tamoxifen 12.2618625569
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0217184923
MESH:D007889 Leiomyoma Curcumin 4.5318555241
MESH:D007938 Leukemia Curcumin 6.5618462866
MESH:D007938 Leukemia Quercetin 6.5617468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.1616106398
MESH:D015458 Leukemia, T-Cell Curcumin 4.7216106398
MESH:D008064 Lipidoses Tamoxifen 3.1217567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.8816943688 17334410 17174718 16239168 11408273 17157831 21278145 11903743 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 10.8818296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.8820032147 19638242 18522880 18407596 18665156
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.6817922224 12958196 14716496 16033810 18006644 17900296 18376398 15650968 18277467 15893842 17823541 20821823 16015684 18156304 12546737 14724832 14716833 16011737 12389079 17976157 12898905 15052691 18472332 17766677 18263696 18418968 15370692 16097048 12445418 11481614 15818738 12741479 12649538 13678700 16136751 18187930 17557913 17525996 15959796 12667390 17869086 18481824 18251166 12632512 18395095 16192424 15925388 17631135 14512876 18166357 17708605 12586293 15673190 17640975 14748882 12445421 18472094 15876570 12666154 16116963 18420326 18705752 16638106 15057751 17761835 18317297 17714472 17944888 12609069 17565644 17698563 15996030 14620537 18279442 15730626 18429990 16248980 15362042 15931870 10355542 18054572 18205269 12632514 18395914 17481882 18412020 18339082 15123356 15338365 17805973 16027843 17721639 18210741
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 8.6818006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.6814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 8.6812741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.6818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.6812878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.5415720792 15830285 16964402 16246199 17285989
MESH:D008107 Liver Diseases Curcumin 6.5416956363
MESH:D008107 Liver Diseases Diethylnitrosamine 6.5417034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.6514706259 16899240
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 21.6719389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 21.6719294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.6719427195 12771043 20118626 18644402 2422723 18977376 20583210 20452335 18978307 19073162 19090486 19499222 19833225 18648771 21071580 19426721 9163691 12112319 19256749 19690152 16942905 21278145 19642983 20101389 19255062 19294768 20501860 15175105 19996281 19254457 21047994 20137499 2862719 19638242 20492335 19812893 10737359 18754104 19551842 19850985 20405173 20434301 21167192 15885732
MESH:D008113 Liver Neoplasms Diethylstilbestrol 21.6715890375 16712894
MESH:D008113 Liver Neoplasms Quercetin 21.6718980244
MESH:D008113 Liver Neoplasms Tamoxifen 21.6716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.6716984957
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 18.3718164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 18.3712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.3717942915 18544905 18164116 16267830 18093689 18079962 17174075 18775883 18253720 18308698 19519916 21159647 19004024 16842330 19126423 17854601 3124819 19539802 9362446 19009564 2563599 18282651
MESH:D008114 Liver Neoplasms, Experimental Quercetin 18.3719519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.3712151625
MESH:D008175 Lung Neoplasms Curcumin 6.5419359593 16243823 18462866
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.5421163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Quercetin 6.5416280456
MESH:D008175 Lung Neoplasms Tamoxifen 6.5418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.5411884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1115166399
MESH:D008223 Lymphoma Curcumin 7.6918462866
MESH:D008223 Lymphoma Diethylstilbestrol 7.6915700306
MESH:D016399 Lymphoma, T-Cell Curcumin 4.6516173963
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.4916002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7219428831
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 14.0812807724
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 14.0816891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 14.0817203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 14.0814580682 11731420 19196722 19196723 16827153
MESH:D020149 Manganese Poisoning Estradiol 12.5519453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.5519453300
MESH:D008545 Melanoma Curcumin 3.4318462866 17885582
MESH:D008545 Melanoma Tamoxifen 3.4319393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1515990972
MESH:D008569 Memory Disorders Curcumin 4.1117263510
MESH:D009101 Multiple Myeloma Curcumin 3.4819372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.8817962980
MESH:D009203 Myocardial Infarction Quercetin 2.9719595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.4516810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.4519207477
MESH:D009361 Neoplasm Invasiveness Curcumin 4.3318495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.679029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5019410462
MESH:D009369 Neoplasms Diethylstilbestrol 5.2815313581
MESH:D009369 Neoplasms Quercetin 5.2815185748
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 10.7512497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.7519189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7017289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 16.1511399458
MESH:D009421 Nervous System Malformations Estradiol 16.1516427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 16.1514600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.6018462866
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.3020387270
MESH:D020078 Neurogenic Inflammation Quercetin 4.3217929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0920387270
MESH:D009765 Obesity Curcumin 4.7419297423
MESH:D009765 Obesity Dietary Fats 4.7421332399 20132043 19632207 17217161 18674790 11836018 18457598 20518802 16723640
MESH:D010024 Osteoporosis Curcumin 3.4418719352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.1819495926
MESH:D010051 Ovarian Neoplasms Curcumin 11.2218462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 11.2219401270
MESH:D010051 Ovarian Neoplasms Progesterone 11.2216525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 11.2219005980
MESH:D010190 Pancreatic Neoplasms Curcumin 8.6317440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.6316540662
MESH:D010190 Pancreatic Neoplasms Quercetin 8.6316965848
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 4.1617698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.1414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6315687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.092563599
MESH:D011230 Precancerous Conditions Quercetin 9.0919056647
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 9.4517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.4511896295 11399792 11222880 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8420887781
MESH:D011471 Prostatic Neoplasms Curcumin 1.8811398177 15129424 18156803 10851300 12497104 18769126 18226269
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.8817136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Quercetin 1.8817292933 14715546
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.2815861022 16919318
MESH:D011656 Pulmonary Emphysema Curcumin 4.4919168576
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.9810666014 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8418045962
MESH:D012509 Sarcoma Curcumin 4.0818462866
MESH:D012554 Schistosomiasis japonica Quercetin 5.5216862918
MESH:D018805 Sepsis Curcumin 4.0418389075
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0216192470
MESH:D013088 Spermatocele Diethylstilbestrol 19.9816709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 19.9816709447
MESH:D013088 Spermatocele Tamoxifen 19.9816709447
MESH:D013119 Spinal Cord Injuries Progesterone 10.7516503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 10.7519457130
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013276 Stomach Ulcer Curcumin 3.4619188055 16631530
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.957505956
MESH:D013978 Tibial Fractures Estradiol 4.6619048282
MESH:D001749 Urinary Bladder Neoplasms Curcumin 11.8518593936
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 11.8516452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Quercetin 11.8516720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.858653321 16712894 17572228
MESH:D014565 Urogenital Neoplasms Curcumin 5.2318462866
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.9916175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.1414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.3415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.3414692618
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4016002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5015869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D015430 Weight Gain Dietary Fats 3.7016723640
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28014
    • No data
    Releated disease ID Related disease Name
    PA446847Arrhythmogenic Right Ventricular Dysplasia
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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