AutismKB 2.0

Annotation Detail for MARCH8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MARCH8 ( MARCH-VIII,MIR,RNF178,c-MIR )
Gene Full Name: membrane-associated ring finger (C3HC4) 8
Band: 10q11.21
Quick LinksEntrez ID:220972; OMIM: 613335; Uniprot ID:MARH8_HUMAN; ENSEMBL ID: ENSG00000165406; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
HEMATOLOGICAL
mean corpuscular volume
Desease Name
Mean corpuscular volume
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MARCH8 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MARCH8 mRNAdecreases expression 19150397
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6812705907 10663392 14986274 10774834 14725611 12958197 17906064 19370779 15968718 12594235 16177239 17562736 11287661 19164858 11834606 16485898 16109766 17522070 11739529 12392966 18071297 15619225 11743745 12153990 16081117 19420014 11421492 2444490 16227642 16393943 16781746 11529661 10915739 19923254 19416960 18713872 19739265 12540782 19085960 14550746 11461765
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D004938 Esophageal Neoplasms marker/mechanism 17068819
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7111587558 19014921 16610002 19784758 16611625 12969438 12587719 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved