AutismKB 2.0

Annotation Detail for FAM171A1


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Basic Information Top
Gene Symbol:FAM171A1 ( C10orf38,FLJ12884,MGC130014,MGC130015 )
Gene Full Name: family with sequence similarity 171, member A1
Band: 10p13
Quick LinksEntrez ID:221061; OMIM: NA; Uniprot ID:F1711_HUMAN; ENSEMBL ID: ENSG00000148468; HGNC ID: 23522
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of FAM171A1 mRNAincreases expression 16788091
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of FAM171A1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of FAM171A1 mRNAincreases expression 19270015
19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of FAM171A1 mRNAaffects binding|increases activity|increases expression 19710929
D014212 Tretinoin Tretinoin results in increased expression of FAM171A1 mRNAincreases expression 16788091
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 4.076195326
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D018248 Adenoma, Liver Cell Phenobarbital 12.3217620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.3216434500
MESH:D000505 Alopecia Tretinoin 3.9415955085
MESH:D001169 Arthritis, Experimental Tretinoin 3.3016412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3316292516
MESH:D001249 Asthma Tretinoin 2.4316456186
MESH:D001471 Barrett Esophagus Tretinoin 4.9116935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.4319483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 10.4316197459 16206674
MESH:D001943 Breast Neoplasms Tretinoin 2.2316873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.2216813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.8816168501
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 3.2120935162 17173139 6705139 1701930 20007298
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 3.211917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3716096774 16051514
MESH:D002386 Cataract Tretinoin 3.3017460283
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.814080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.2216129372
MESH:D002779 Cholestasis pirinixic acid 3.1219176532
MESH:D002822 Choriocarcinoma Tretinoin 5.8816461808
MESH:D002972 Cleft Palate Tretinoin 2.809407595
MESH:D003092 Colitis Tretinoin 4.2617035595
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.839664655 9224671 10589399 9125849 14991402 9211117 16925845 9142499 17551590 8800419
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D004421 Dystonia Phenobarbital 4.471851702
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D004489 Edema, Cardiac Tretinoin 5.1918230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.3516569247
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.673659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.593922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0620417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.916401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.817750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.653659116
MESH:D005124 Eye Abnormalities Tretinoin 3.879664655 16938888
MESH:D005234 Fatty Liver pirinixic acid 3.1919236843 20131406
MESH:D005355 Fibrosis Tretinoin 4.0717994277
MESH:D005909 Glioblastoma Tretinoin 3.2417312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.4416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.8816084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.079664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006529 Hepatomegaly Phenobarbital 10.4116109766
MESH:D006529 Hepatomegaly pirinixic acid 10.4116221962 18467677 19176532 19772884
MESH:D006930 Hyperalgesia Tretinoin 3.5316870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.1316778211
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007410 Intestinal Diseases Tretinoin 4.3317994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.3315992940 17551590
MESH:D007938 Leukemia Tretinoin 2.9317143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.1216482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1219850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.3917301526 16891316 12679006 19642359 16140955 19035177 16935935 17107899 19225113 17339181 17217047 16788101 17361223 17712046 17506722 19075265 15748426 17649720 17294898 9834237 16766008 17368321 16823087 16331271 19029980
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.589224671
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0821047994
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4315474484
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.4316248980 18397230
MESH:D008107 Liver Diseases Phenobarbital 2.2419363144
MESH:D008113 Liver Neoplasms Phenobarbital 4.878742319 19812893 15975961 21047994 19073162 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 4.8715890375 20007298 16377806
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.922563599 1399818 18308698 17172636 6150874
MESH:D008527 Medulloblastoma Tretinoin 2.9117453147
MESH:D008545 Melanoma Tretinoin 1.9816752155
MESH:D008591 Meningomyelocele Tretinoin 4.9916940565
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.2817596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.1117484760
MESH:D009369 Neoplasms pirinixic acid 5.4717405874
MESH:D009369 Neoplasms Tretinoin 5.4716946489 16594593
MESH:D009421 Nervous System Malformations Tretinoin 4.289125849
MESH:D009436 Neural Tube Defects Tretinoin 3.299142499
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010018 Osteomalacia Phenobarbital 5.0017016548
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4416936753
MESH:D010146 Pain Tretinoin 3.2416870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.6616965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.6615976015
MESH:D011230 Precancerous Conditions Phenobarbital 3.992563599
MESH:D011507 Proteinuria Tretinoin 4.0716636307
MESH:D019310 Pseudolymphoma Phenobarbital 5.2212752131
MESH:D011625 Pterygium Tretinoin 5.4216723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.5616283617 16116481
MESH:D012640 Seizures Phenobarbital 2.9511442880 3137016 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.456407741
MESH:D012878 Skin Neoplasms Tretinoin 2.7616467112
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013964 Thyroid Neoplasms Phenobarbital 8.231399818
MESH:D013964 Thyroid Neoplasms Tretinoin 8.2316026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 4.1816051514
MESH:D014376 Tuberculosis Tretinoin 3.4516040207
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 4.0716129372
MESH:D014604 Uveal Neoplasms Tretinoin 5.3316752155
MESH:D014820 Vitiligo Tretinoin 4.5616761959
MESH:D009396 Wilms Tumor Tretinoin 4.3416287080
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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