Annotation Detail for GPR115
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of GPR115 mRNA | increases expression | 20106945
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of GPR115 mRNA | increases expression | 16002434
|
| D005038 |
Ethylnitrosourea |
Ethylnitrosourea results in increased mutagenesis of GPR115 gene | increases mutagenesis | 16495775
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000236 |
Adenoma |
|
Ethylnitrosourea |
3.94 | 6695378 |
| MESH:D001927 |
Brain Diseases |
|
Ethylnitrosourea |
5.33 | 14991843 |
| MESH:D001932 |
Brain Neoplasms |
|
Ethylnitrosourea |
4.74 | 16357521 18412241 16651633 16436596 15144691 |
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.56 | 11237771 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
2.72 | 11237771 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
7.91 | 12371664 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Ethylnitrosourea |
7.91 | 16003739 |
| MESH:D016543 |
Central Nervous System Neoplasms |
|
Ethylnitrosourea |
6.85 | 17160924 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.24 | 19486331 |
| MESH:D004476 |
Ectodermal Dysplasia |
|
Ethylnitrosourea |
6.85 | 18357618 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
4.52 | 15138306 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.34 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.79 | 12639820 12168785 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.96 | 8708960 |
| MESH:D005909 |
Glioblastoma |
|
Ethylnitrosourea |
4.10 | 16436596 |
| MESH:D005910 |
Glioma |
|
Ethylnitrosourea |
3.63 | 18412241 16357521 16651633 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.16 | 15720958 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.23 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.31 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.56 | 18776723 10903974 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
8.94 | 12371664 |
| MESH:D007680 |
Kidney Neoplasms |
|
Ethylnitrosourea |
8.94 | 17379185 |
| MESH:D008175 |
Lung Neoplasms |
|
Ethylnitrosourea |
2.63 | 17703301 6695378 16271038 16019985 |
| MESH:D008223 |
Lymphoma |
|
Ethylnitrosourea |
4.25 | 15790496 |
| MESH:D016399 |
Lymphoma, T-Cell |
|
Ethylnitrosourea |
5.70 | 15375218 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Ethylnitrosourea |
3.77 | 10767621 18041768 10838139 |
| MESH:D008579 |
Meningioma |
|
Ethylnitrosourea |
6.85 | 17943659 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.65 | 16801185 |
| MESH:D009374 |
Neoplasms, Experimental |
|
Ethylnitrosourea |
5.05 | 16707424 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.31 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.70 | 18481113 19348381 |
| MESH:D009442 |
Neurilemmoma |
|
Ethylnitrosourea |
6.16 | 17160924 16003739 16651423 |
| MESH:D009837 |
Oligodendroglioma |
|
Ethylnitrosourea |
6.85 | 17160924 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.64 | 12371664 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.52 | 15572423 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.48 | 12479363 16644109 18247401 16289102 15754350 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.34 | 16882103 |
| MESH:D013953 |
Thymus Neoplasms |
|
Ethylnitrosourea |
5.90 | 15790496 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.85 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.31 | 17120751 |
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