AutismKB 2.0

Annotation Detail for KIF6


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Basic Information Top
Gene Symbol:KIF6 ( C6orf102,DKFZp451I2418,MGC33317,dJ1043E3.1,dJ137F1.4,dJ188D3.1 )
Gene Full Name: kinesin family member 6
Band: 6p21.2
Quick LinksEntrez ID:221458; OMIM: NA; Uniprot ID:KIF6_HUMAN; ENSEMBL ID: ENSG00000164627; HGNC ID: 21202
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1918Atherosclerosis
Desease Name
Attention deficit hyperactivity disorder symptoms (interaction)
PSYCH
Desease Name
Attention deficit hyperactivity disorder symptoms (interaction)
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KIF6 mRNAaffects expression 16483693
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KIF6 mRNA]decreases reaction|increases expression 20360939
D004052 Diethylnitrosamine caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KIF6 mRNA]decreases reaction|increases expression 20360939
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of KIF6 mRNAincreases expression 20360939
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D000236 Adenoma Diethylnitrosamine 3.0810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.6416434500 17620307 17162532 19061943 18056438 19052882
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1917474063
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 1.8820084675 20935162 19539802 20524982 18788625 17428255 19052882 17162532 16288022 16698587 19519916 16540662 16328049 20512989 20727157 19822196 16878318 19418558 19919837 10737359 20514400 18665156 18393292 11831363 3084413 18971187 18785209 16779866 19208518 21159647 17138121 16681979 16502159 18691550 17173139 18056438 19701751 20432363 17761372 18494052 17978847 20007298 19394651 3581430 16807293 18978308 16569478 19107877 19171122 19335982 10672840 19383236 17055752 16830150 18506893 16935385 18210153 20214788 20101231
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.1521159647 17174075 7505956 2727394
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.1019052882
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2720387270
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.1519107877
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.9816302075
MESH:D005234 Fatty Liver Diethylnitrosamine 3.6720387270 21071580
MESH:D007249 Inflammation Diethylnitrosamine 2.5718785209
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 5.0310783313
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.7715369732
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 4.2616766008
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 3.0318665156 18407596 20032147 19638242 18522880
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1817034775
MESH:D008113 Liver Neoplasms Diethylnitrosamine 2.3620501860 9163691 19551842 19256749 19642983 18648771 19073162 12771043 2862719 21278145 19850985 12112319 20434301 19426721 20583210 19690152 19833225 20492335 19090486 10737359 2422723 19294768 19427195 18977376 21071580 18644402 15885732 15175105 21047994 18754104 21167192 19499222 19255062 20452335 16942905 19254457 19996281 20137499 20118626 19638242 18978307 20405173 19812893 20101389
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 2.883124819 18544905 2563599 16267830 19519916 19539802 9362446 18079962 17854601 17942915 18308698 19009564 16842330 18775883 18093689 18253720 19004024 18164116 19126423 18282651 17174075 21159647
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.7720970405 21163286 20512841 6695378
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.703581430 9029167
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.7320387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.9820387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5416540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.972563599
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.327505956
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134920075
  • No data
    Releated disease ID Related disease Name
    PA447197Attention Deficit Disorder with Hyperactivity
    PA445019Myocardial Infarction
    Releated drug ID Related drug Name
    PA451089pravastatin
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018