AutismKB 2.0

Annotation Detail for FEN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FEN1 ( FEN-1,MF1,RAD2 )
Gene Full Name: flap structure-specific endonuclease 1
Band: 11q12.2
Quick LinksEntrez ID:2237; OMIM: 600393; Uniprot ID:FEN1_HUMAN; ENSEMBL ID: ENSG00000168496; HGNC ID: 3650
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03450Non-homologous end-joining
hsa03030DNA replication
hsa03410Base excision repair
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Chromosome Maintenance
DNA Repair
No data
No data
Pathway IDPathway Name
500945Removal of DNA patch containing abasic residue
500672Removal of the Flap Intermediate from the C-strand
500992Removal of the Flap Intermediate
500724Early Phase of HIV Life Cycle
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1809HIV infection
2066Lung cancer
2259Hereditary disease
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of FEN1 mRNAaffects expression 21346803
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of FEN1 proteinaffects expression 20106945
C103505 AM 251 AM 251 results in decreased expression of FEN1 mRNAdecreases expression 16500647
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FEN1 mRNAaffects expression 16483693
D001374 Azacitidine [Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNAaffects cotreatment|affects expression 18720364
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FEN1 mRNAdecreases expression 20382639
C006780 bisphenol A bisphenol A results in increased expression of FEN1 mRNAincreases expression 16474171
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of FEN1 mRNAdecreases expression 15336504
12414654
C030123 coumarin coumarin results in increased expression of FEN1 mRNAincreases expression 18480146
D016572 Cyclosporine Cyclosporine results in increased expression of FEN1 mRNAincreases expression 20106945
D002945 Cisplatin FEN1 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of FEN1 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FEN1 mRNA]decreases reaction|increases expression 17854601
D004958 Estradiol Estradiol results in increased expression of FEN1 mRNAincreases expression 16474171
D004958 Estradiol Estradiol affects the expression of FEN1 mRNAaffects expression 15598610
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of FEN1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of FEN1 mRNAincreases expression 16174780
17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FEN1 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of FEN1 mRNAincreases expression 16174780
D005472 Fluorouracil FEN1 affects the susceptibility to Fluorouracilaffects response to substance 15067352
D005472 Fluorouracil Fluorouracil results in increased expression of FEN1 mRNAincreases expression 15109396
D019833 Genistein Genistein results in increased expression of FEN1 mRNAincreases expression 16474171
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of FEN1 mRNAdecreases expression 12414654
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of FEN1 mRNAincreases expression 17616710
C006253 pirinixic acid pirinixic acid results in decreased expression of FEN1 mRNAdecreases expression 17426115
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of FEN1 mRNAincreases expression 16474171
D011374 Progesterone Progesterone results in decreased expression of FEN1 mRNAdecreases expression 16966611
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in decreased expression of FEN1 mRNAdecreases expression 16678137
C017947 sodium arsenite sodium arsenite results in decreased expression of FEN1 mRNAdecreases expression 12377979
C017947 sodium arsenite sodium arsenite results in increased expression of FEN1 proteinincreases expression 19072884
D013629 Tamoxifen Tamoxifen affects the expression of FEN1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of FEN1 mRNAdecreases expression 16714409
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FEN1 mRNAaffects cotreatment|increases expression 17942748
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of FEN1 mRNAincreases expression 19031421
D013792 Thalidomide [Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNAaffects cotreatment|affects expression 18720364
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of FEN1 mRNAdecreases expression 17951470
D014212 Tretinoin Tretinoin results in decreased expression of FEN1 mRNAdecreases expression 16249480
16054129
D014747 Vinblastine FEN1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D024483 Vitamin K 3 Vitamin K 3 results in decreased expression of FEN1 mRNAdecreases expression 12414654
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2514745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.7315322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 7.738333272
MESH:D000138 Acidosis Ammonium Chloride 3.2618287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6417505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.7015814532 17670903 12690470
MESH:D055371 Acute Lung Injury pirinixic acid 2.8518653653
MESH:D000230 Adenocarcinoma Cisplatin 12.7017638652 11798837
MESH:D000230 Adenocarcinoma Estradiol 12.7011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.7014692618
MESH:D000230 Adenocarcinoma Fluorouracil 12.7017638652
MESH:D000230 Adenocarcinoma Genistein 12.7011473722
MESH:D000236 Adenoma Diethylnitrosamine 2.686695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.5619061943 19052882 16434500 17620307 18056438 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.5616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.5616835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.4015276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.6016712894 17306315
MESH:D000505 Alopecia Tretinoin 3.3815955085
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 4.1716510725
MESH:D000740 Anemia Fluorouracil 7.8315504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.8311748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.3215885639
MESH:D001169 Arthritis, Experimental Thalidomide 11.329598899
MESH:D001169 Arthritis, Experimental Tretinoin 11.3216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1916292516
MESH:D001249 Asthma Tretinoin 2.2516456186
MESH:D001471 Barrett Esophagus Tretinoin 4.1216935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.7419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.7412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.7416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5815746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.5914601052
MESH:D001862 Bone Resorption bisphenol A 3.6011985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.0417868700
MESH:D001930 Brain Injuries Progesterone 3.9715665606 15845082 15380490
MESH:D001943 Breast Neoplasms bisphenol A 6.6717123778
MESH:D001943 Breast Neoplasms Cisplatin 6.6718382427 19526202
MESH:D001943 Breast Neoplasms Diethylnitrosamine 6.6717474063
MESH:D001943 Breast Neoplasms Estradiol 6.6712948864 18497071 17289903 19861407 14630087 17018787 17261762 16675129
MESH:D001943 Breast Neoplasms Fluorouracil 6.6719217205 16557594 15136595 16110121 16595493 18357371 18608205
MESH:D001943 Breast Neoplasms Genistein 6.6716873071 16541309 17200150
MESH:D001943 Breast Neoplasms Progesterone 6.6716175315 15562024 17614352
MESH:D001943 Breast Neoplasms Tamoxifen 6.6718855134 21152245 18351453 20005174 20135344 19410462 19115204 17440819 11161223 20390343 19084267 18821012 15668708 19142967 18629630 19289846 19155303 21138602 19011961 16818667 20859285 20065188 15565566 18984771 19189212 19103187 17893378 18425577 19189210 16273361 20544844 19059307 18815881 16202921 19288272 19066611 19221464 17242785 18997820 17261762 16873071 17049068 19200415 19487384 19244106
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.6720435547
MESH:D001943 Breast Neoplasms Tretinoin 6.6716873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2916813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1716111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.3716051944
MESH:D002277 Carcinoma Fluorouracil 7.4217121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.4216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2219066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8616168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 24.9516705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 24.9512907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 24.9517982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 24.9517173139 18978308 3581430 16569478 19052882 20512989 18393292 16935385 18788625 16830150 20084675 20214788 16502159 16698587 19701751 20727157 19394651 16540662 19919837 20007298 19539802 19107877 17138121 19383236 19171122 20524982 17978847 18494052 20514400 20432363 17055752 16681979 18785209 18691550 10672840 19519916 16288022 18056438 18210153 18971187 19208518 17428255 16878318 21159647 17761372 10737359 16328049 18665156 18506893 11831363 3084413 16779866 19335982 19418558 16807293 19822196 20935162 20101231 17162532
MESH:D006528 Carcinoma, Hepatocellular Estradiol 24.9516924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 24.9517088986 16332177 16799960 18930000 17971768 17045692
MESH:D006528 Carcinoma, Hepatocellular Genistein 24.9516924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 24.9516507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 24.9516924424
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 24.9516313753
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 24.951917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.6917123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.9312023789 16685392
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.4418695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 6.441485588
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 13.386189445 17066447 18337622
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 13.3816757204 17066447 18986760 16280240
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 13.3818572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 13.3818922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.3816051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2118850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Genistein 6.8616332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 6.8616936243
MESH:D002386 Cataract Tretinoin 2.9217460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 23.736135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 23.7320889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 23.7312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 23.7317174075 7505956 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 23.7318566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 23.7320056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2916129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 14.7719052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 14.7716835633
MESH:D018281 Cholangiocarcinoma Thalidomide 14.7718291259
MESH:D002779 Cholestasis Cyclosporine 12.0919486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.0916919318 17333356 16105132 17110522 17681005 11677210 15861022
MESH:D002779 Cholestasis pirinixic acid 12.0919176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3515340226 16354765 8697196 15668235 12621046
MESH:D002972 Cleft Palate Tretinoin 5.359407595
MESH:D003092 Colitis Thalidomide 8.9316680017
MESH:D003092 Colitis Tretinoin 8.9317035595
MESH:D003110 Colonic Neoplasms Fluorouracil 3.6517725105 17018589 15001691 17172411 17169374 17287894 16510598 18772588 17016597 16340194
MESH:D003110 Colonic Neoplasms Genistein 3.6517182828
MESH:D015179 Colorectal Neoplasms Azacitidine 6.1819934284
MESH:D015179 Colorectal Neoplasms Cisplatin 6.1815273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 6.1817255274 17401013 15289873 20501625 17594712 16303861 17094418 16282729 17016601 18949393 16391804 15148649 14970324 17454858 18448328 18288408 18802399 16331619 17695437 18509181 16524972 18383874
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 6.1815531428
MESH:D015179 Colorectal Neoplasms Vinblastine 6.1818802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8114669216 17141729
MESH:D016510 Corneal Neovascularization Thalidomide 5.289301478
MESH:D003389 Cranial Nerve Diseases Thalidomide 6.019200351
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7120055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Thalidomide 3.719200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.719211117 10589399 9142499 16925845 8800419 17551590 9224671 14991402 9125849 9664655
MESH:D003424 Crohn Disease Thalidomide 4.0216078585
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.7318551238
MESH:D007644 Darier Disease Fluorouracil 4.5016733453
MESH:D003704 Dementia Polychlorinated Biphenyls 4.4416140633
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0719031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2918249437
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 9.6319647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.6320387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 9.6316647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.6317107852
MESH:D003928 Diabetic Nephropathies Estradiol 8.0219279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.0219279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.2017187935
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 5.6421346803 18551238
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.6419107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.6420420201
MESH:D004362 Drug Toxicity Cisplatin 7.4612649298 12231392 19839026 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.4611462148
MESH:D004487 Edema pirinixic acid 9.9512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.9511000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 9.957812673 16716910 8113982 15177302 8273558 11698051 9599246
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.9418230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.9418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.6912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.6917692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.6919031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.2916402032
MESH:D016889 Endometrial Neoplasms Estradiol 16.2011473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 16.2011473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 16.2020544844 17893378 16202921 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 16.2016569247
MESH:D004715 Endometriosis Progesterone 8.0816134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.089294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8216302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.7820426865
MESH:D004938 Esophageal Neoplasms Cisplatin 9.7815173087 17638652 15464296 16481741 16785472
MESH:D004938 Esophageal Neoplasms Fluorouracil 9.7816785472 15173087 16337965 16481741 17638652
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 9.7816805852 15264214 15623463 15878914 16704527 15547733 15547721 16510608 15150132
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.1111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.119664655 16938888
MESH:D005234 Fatty Liver Cyclosporine 21.8319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 21.8321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 21.8315345470
MESH:D005234 Fatty Liver pirinixic acid 21.8320131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 21.8314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0616709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1711858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2314745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8919069698
MESH:D005355 Fibrosis Cyclosporine 13.0412639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.0420067830
MESH:D005355 Fibrosis Tretinoin 13.0417994277
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3816452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 6.0112701121
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.928708960
MESH:D005909 Glioblastoma Genistein 6.5716598420
MESH:D005909 Glioblastoma Tretinoin 6.5717312396
MESH:D005910 Glioma Fluorouracil 6.0716145905
MESH:D005910 Glioma Thalidomide 6.0716327979
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2910696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 11.8615102660 15464296
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.8618337622 15162350 15102660
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.8616096774
MESH:D034381 Hearing Loss Cisplatin 4.0519898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8616084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.1815464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.0210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.029664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.3620558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0711000095
MESH:D006529 Hepatomegaly pirinixic acid 7.3016221962 18467677 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.3016120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.7315709030
MESH:D006689 Hodgkin Disease Cisplatin 11.0016170182 16200630
MESH:D006689 Hodgkin Disease sodium arsenite 11.0012676792
MESH:D006689 Hodgkin Disease Vinblastine 11.0018501091 18180244
MESH:D019584 Hot Flashes Estradiol 3.4517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.758697196 16354765 15340226 16959395 18606429
MESH:D006930 Hyperalgesia Tretinoin 2.9816870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2816778211
MESH:D006943 Hyperglycemia pirinixic acid 2.9320558911
MESH:D006973 Hypertension Cyclosporine 4.5610903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.5618670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5216945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.1115869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.9917937319
MESH:D007248 Infertility, Male sodium arsenite 5.9912646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 17.9618785209
MESH:D007249 Inflammation Progesterone 17.9615869954
MESH:D007249 Inflammation Tamoxifen 17.9619457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 17.9612878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 17.967812673 15177302 8273558 7562506 11698051
MESH:D007249 Inflammation Thalidomide 17.9616134734
MESH:D007333 Insulin Resistance bisphenol A 11.2116393666
MESH:D007333 Insulin Resistance Estradiol 11.2116627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 11.2116306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4817994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.0516580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.0517551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1415604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.8415464296
MESH:D007674 Kidney Diseases Cisplatin 13.0619839026 12649298 12231392 15190930 18289764
MESH:D007674 Kidney Diseases Cyclosporine 13.068314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 13.0615618244
MESH:D007674 Kidney Diseases sodium arsenite 13.0620008137
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.0116518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 20.8116705839
MESH:D007680 Kidney Neoplasms Cyclosporine 20.8112371664
MESH:D007680 Kidney Neoplasms Estradiol 20.8115610895
MESH:D007680 Kidney Neoplasms Fluorouracil 20.8116985049
MESH:D007680 Kidney Neoplasms Tamoxifen 20.8118625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.4911231351
MESH:D007898 Leishmaniasis, Visceral Thalidomide 4.1216514283
MESH:D007938 Leukemia Azacitidine 9.7519148494
MESH:D007938 Leukemia Genistein 9.7518980019 17468513
MESH:D007938 Leukemia Tretinoin 9.7517143497
MESH:D007951 Leukemia, Myeloid Azacitidine 8.9119077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.9116932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 6.0317596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 6.0318720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.0319850784 16294345 17596541
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.9219299654
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9617301526 12679006 17107899 16788101 19225113 17506722 19029980 16823087 16935935 17294898 15748426 9834237 17368321 17712046 17339181 17649720 17217047 19035177 16766008 17361223 16331271 19075265 16140955 16891316 19642359
MESH:D017880 Limb Deformities, Congenital Thalidomide 7.8610473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.869224671
MESH:D008064 Lipidoses Tamoxifen 2.9515342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.5118665156 18407596 18522880 19638242 20032147
MESH:D008103 Liver Cirrhosis Thalidomide 6.5117174718 16943688
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.3014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 10.3017823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.3015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.3018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.3012878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 10.3015465738
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.3018397230 16248980
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0317034775
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 23.937678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 23.932125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Diethylnitrosamine 23.9319642983 19254457 21071580 19638242 16942905 19690152 20118626 20452335 18978307 21278145 19427195 18644402 10737359 19812893 2422723 20101389 20492335 12771043 15885732 15175105 19256749 21047994 19090486 20137499 20405173 18754104 19073162 18648771 19551842 19499222 2862719 19426721 19833225 12112319 9163691 19996281 20501860 19850985 20434301 19255062 19294768 21167192 18977376 20583210
MESH:D008113 Liver Neoplasms Fluorouracil 23.9315113037 16603448 18383874 17045692
MESH:D008113 Liver Neoplasms pirinixic acid 23.9315890375 16377806 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 23.9315276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 23.9316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.9316984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 16.702876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 16.708603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 16.7018079962 17174075 19539802 21159647 3124819 19126423 19009564 18164116 17942915 19004024 18775883 18253720 18544905 2563599 16267830 18093689 17854601 9362446 18282651 19519916 18308698 16842330
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 16.701423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.7012151625
MESH:D008171 Lung Diseases sodium arsenite 2.9819095001
MESH:D008175 Lung Neoplasms Aflatoxin B1 14.6314755239
MESH:D008175 Lung Neoplasms Azacitidine 14.6321224363
MESH:D008175 Lung Neoplasms Cisplatin 14.6317225452 11798837 6189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 14.636695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Fluorouracil 14.6315246190
MESH:D008175 Lung Neoplasms sodium arsenite 14.6316712894 17077188 17306315 19931552 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 14.6318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 14.6311884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 14.6311807781
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.5015086387
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.4719428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.8311408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 16.8312929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 16.8311408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 16.8314580682 19196722 11731420 19196723 16827153
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 16.838985016
MESH:D020149 Manganese Poisoning Estradiol 11.6519453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.6519453300
MESH:D008527 Medulloblastoma Tretinoin 2.6717453147
MESH:D008545 Melanoma Cisplatin 14.5417023156 18176117 16248763 16809738 16432458 12883367 15577323 12374674 17761969 18332650 18505091 12393984 11135225
MESH:D008545 Melanoma sodium arsenite 14.5416487513 19082730
MESH:D008545 Melanoma Tamoxifen 14.5412393984 19393235
MESH:D008545 Melanoma Thalidomide 14.5416098027 17089043 12829675
MESH:D008545 Melanoma Tretinoin 14.5416752155
MESH:D008545 Melanoma Vinblastine 14.5415577320 16809738 18332650 15577323 18176117 16432458 12374674 18505091 16248763 17761969
MESH:D008545 Melanoma Vitamin K 3 14.5419082730
MESH:D018328 Melanoma, Amelanotic Cisplatin 10.5215990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 10.5215990972
MESH:D008591 Meningomyelocele Tretinoin 4.1416940565
MESH:D008654 Mesothelioma Cisplatin 3.1317638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4916801185
MESH:D009006 Monosomy Azacitidine 5.7819299654
MESH:D009062 Mouth Neoplasms Fluorouracil 3.4116757204 18986760
MESH:D009101 Multiple Myeloma Azacitidine 7.3118443271 19549372
MESH:D009101 Multiple Myeloma Thalidomide 7.3117168659 19112201 16445831 19112817 15920492 15867202 15741222 19372569 15939924 15744524
MESH:D009135 Muscular Diseases pirinixic acid 3.2216239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 11.5919805378 17596541 18720364 17611569
MESH:D009190 Myelodysplastic Syndromes Thalidomide 11.5918720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 11.5917596541
MESH:D009203 Myocardial Infarction Genistein 5.2617141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.2619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7912213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.8816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.8817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.8816411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.5718551238 7678174
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.339029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.3319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4219410462
MESH:D009369 Neoplasms Cisplatin 14.1616773208
MESH:D009369 Neoplasms Fluorouracil 14.1618239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 14.1617405874
MESH:D009369 Neoplasms sodium arsenite 14.1611559025
MESH:D009369 Neoplasms Tretinoin 14.1616946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3820056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7019196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4417289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.1915464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0419348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 34.6111399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 34.6111399458 16427766
MESH:D009421 Nervous System Malformations Genistein 34.6116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 34.6114600291
MESH:D009421 Nervous System Malformations Thalidomide 34.6116859833
MESH:D009421 Nervous System Malformations Tretinoin 34.619125849
MESH:D009436 Neural Tube Defects sodium arsenite 6.6812854658
MESH:D009436 Neural Tube Defects Tretinoin 6.689142499
MESH:D009447 Neuroblastoma Cisplatin 3.308761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.1020387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.408761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8220387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.2416436463
MESH:D009503 Neutropenia Vinblastine 4.3017378895
MESH:D009765 Obesity pirinixic acid 1.7420558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.1816049721
MESH:D010024 Osteoporosis Genistein 3.0719401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8116169203
MESH:D010049 Ovarian Diseases bisphenol A 4.6911985600
MESH:D010051 Ovarian Neoplasms Cisplatin 21.4519769630 6897625 17225452 15464296
MESH:D010051 Ovarian Neoplasms Estradiol 21.4519401270
MESH:D010051 Ovarian Neoplasms Genistein 21.4519005980
MESH:D010051 Ovarian Neoplasms Progesterone 21.4516525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 21.4517306315 15276417
MESH:D010051 Ovarian Neoplasms Thalidomide 21.4516288038
MESH:D010051 Ovarian Neoplasms Tretinoin 21.4516936753
MESH:D010146 Pain AM 251 6.5018987195
MESH:D010146 Pain Tretinoin 6.5016870215
MESH:D010190 Pancreatic Neoplasms AM 251 19.0916500647
MESH:D010190 Pancreatic Neoplasms Cisplatin 19.0919003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 19.0916540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 19.0916929163 19003803 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 19.0915976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 19.0915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4111578682
MESH:D010212 Papilloma Hydrogen Peroxide 8.6512065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 8.6512065085 18404319 8330346 18922899
MESH:D010291 Paresis Thalidomide 6.019200351
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.2816702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9512520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.0315464296
MESH:D010997 Pleural Neoplasms Cisplatin 5.0417638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2818163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.1212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.122563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 4.0717031469
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.5210548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.5211222880 11896295 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.6720887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.6720887781
MESH:D011471 Prostatic Neoplasms Azacitidine 2.8518324645
MESH:D011471 Prostatic Neoplasms bisphenol A 2.8516740699
MESH:D011471 Prostatic Neoplasms Estradiol 2.8516740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.8519082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 2.8515256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.8515721890
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.8516039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.8515067354
MESH:D011471 Prostatic Neoplasms Thalidomide 2.8516729912
MESH:D011507 Proteinuria Tretinoin 3.3316636307
MESH:D011536 Prurigo Thalidomide 6.0112755975
MESH:D011537 Pruritus Ethinyl Estradiol 3.0216919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1216882103
MESH:D011625 Pterygium Tretinoin 4.5016723453
MESH:D011629 Puberty, Precocious bisphenol A 4.4910548101
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7615538739 16160472 18722050 18286688
MESH:D051437 Renal Insufficiency Cisplatin 4.1215464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.2419058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5618990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8316116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7518045962
MESH:D012512 Sarcoma, Ewing's Cisplatin 4.1514601052
MESH:D019873 Schnitzler Syndrome Thalidomide 5.6416096327
MESH:D012640 Seizures 2,6-dinitrotoluene 2.3418551238
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 20.6512065085
MESH:D012878 Skin Neoplasms sodium arsenite 20.6518572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 20.658532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 20.6516192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 20.6518404319 8985016 8330346 11807781 12065085
MESH:D012878 Skin Neoplasms Tretinoin 20.6516467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.0415464296
MESH:D013088 Spermatocele Ethinyl Estradiol 10.5616709447
MESH:D013088 Spermatocele Tamoxifen 10.5616709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.8915862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.8919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5712854658
MESH:D013274 Stomach Neoplasms Cisplatin 6.0618396642 17522103 15958060
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.0618456281
MESH:D013274 Stomach Neoplasms Fluorouracil 6.0619084572 18396642 17498489 17172411 15786421 17522103 18567086 16424979 16951190 19015929
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 6.0617575124 12958204
MESH:D013274 Stomach Neoplasms Tretinoin 6.0617261132
MESH:D013276 Stomach Ulcer Thalidomide 3.9215138204
MESH:D019966 Substance-Related Disorders bisphenol A 3.6916684133 16045194
MESH:D013736 Testicular Neoplasms Cisplatin 4.3615464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.447505956
MESH:D013964 Thyroid Neoplasms Tretinoin 6.4416026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.3919048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.9816280240
MESH:D014062 Tongue Neoplasms Tretinoin 8.9816051514
MESH:D014376 Tuberculosis Tretinoin 3.0516040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 10.9716049721
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 10.9712973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 10.9711723127 17306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 10.9717572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.0210091137
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 20.5416803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 20.5416803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 20.5411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 20.5416129372
MESH:D014591 Uterine Diseases bisphenol A 4.7114652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0214692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.3116752155
MESH:D014605 Uveitis Cyclosporine 3.681336536
MESH:D014625 Vaginal Neoplasms Cisplatin 10.3415577323
MESH:D014625 Vaginal Neoplasms Vinblastine 10.3415577323
MESH:D014652 Vascular Diseases sodium arsenite 11.1417056641
MESH:D014652 Vascular Diseases Thalidomide 11.1415741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2912125929
MESH:D014689 Venous Insufficiency coumarin 5.4812708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2814671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.7816761959
MESH:D014839 Vomiting Cisplatin 4.4211897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9515886252
MESH:D009396 Wilms Tumor Tretinoin 3.7216287080
MESH:D014985 Xerophthalmia Cyclosporine 4.1417120751
Pathway ID Pathway Name
KEGG:03410 Base excision repair
REACT:152 Cell Cycle, Mitotic
REACT:22172 Chromosome Maintenance
REACT:216 DNA Repair
REACT:383 DNA Replication
KEGG:03030 DNA replication
KEGG:03450 Non-homologous end-joining
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28090
    • No data
    Releated disease ID Related disease Name
    PA445742Stomach Neoplasms
    Releated drug ID Related drug Name
    PA449957ibuprofen
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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