AutismKB 2.0

Annotation Detail for FGF2


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Basic Information Top
Gene Symbol:FGF2 ( BFGF,FGFB,HBGF-2 )
Gene Full Name: fibroblast growth factor 2 (basic)
Band: 4q28.1
Quick LinksEntrez ID:2247; OMIM: 134920; Uniprot ID:FGF2_HUMAN; ENSEMBL ID: ENSG00000138685; HGNC ID: 3676
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04810Regulation of actin cytoskeleton
hsa05218Melanoma
hsa05200Pathways in cancer
Pathway IDPathway Name
Signaling by Insulin receptor
Signaling by FGFR
Pathway IDPathway Name
200066Angiopoietin receptor Tie2-mediated signaling
200115Syndecan-4-mediated signaling events
200109Integrins in angiogenesis
200021Glypican 1 network
Pathway IDPathway Name
P00005Angiogenesis
P00021FGF signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1818Systemic scleroderma
1850Herpes
1895Gestational diabetes
1901Endometriosis
1904Diabetes mellitus
1934Cancer
1954Stroke
1986Eating disorder
2044Pre-Eclampsia
2074Asthma
2075Heart failure
2100Hepatitis C
2231Arthritis
2233Cirrhosis
2240Anemia
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C046782 14,15-epoxy-5,8,11-eicosatrienoic acid 14,15-epoxy-5,8,11-eicosatrienoic acid results in increased expression of FGF2 proteinincreases expression 16286479
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased expression of and results in increased activity of HIF1A protein]decreases reaction|increases activity|increases expression 15631803
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased phosphorylation of AKT1 protein]decreases reaction|increases phosphorylation 15631803
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased phosphorylation of AKT1 protein]decreases reaction|increases phosphorylation 16303940
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased stability of and results in increased expression of COL1A1 protein]decreases reaction|increases expression|increases stability 16303940
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased stability of and results in increased expression of COL1A2 protein]decreases reaction|increases expression|increases stability 16303940
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[FGF2 protein binds to and results in increased activity of FGFR4 protein] which results in increased phosphorylation of MAPK1 protein]affects binding|decreases reaction|increases activity|increases phosphorylation 11336793
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of FGF2 mRNAincreases expression 20406850
C082182 3,5-diiodothyropropionic acid 3,5-diiodothyropropionic acid results in increased expression of FGF2 proteinincreases expression 16384862
C075773 4-phenylbutyric acid 4-phenylbutyric acid results in decreased expression of FGF2 mRNAdecreases expression 14583596
D000111 Acetylcysteine Acetylcysteine results in decreased expression of FGF2 mRNAdecreases expression 16084531
D000117 Acetylglucosamine Acetylglucosamine analog promotes the reaction [FGF2 protein binds to FGFR1 protein]affects binding|increases reaction 12440867
D020106 Acrylamide Acrylamide analog promotes the reaction [FGF2 protein binds to FGFR1 protein]affects binding|increases reaction 12440867
D020106 Acrylamide Acrylamide analog inhibits the reaction [Trifluoroacetic Acid results in increased degradation of FGF2 protein]decreases reaction|increases degradation 14733594
D020106 Acrylamide Acrylamide analog promotes the reaction [FGF2 protein binds to FGF2 protein]affects binding|increases reaction 14733594
C006453 alliin alliin results in decreased activity of FGF2 proteindecreases activity 16351512
C006453 alliin Ascorbic Acid promotes the reaction [alliin results in decreased activity of FGF2 protein]decreases activity|increases reaction 16351512
C006453 alliin Vitamin E promotes the reaction [alliin results in decreased activity of FGF2 protein]decreases activity|increases reaction 16351512
C006453 alliin alliin promotes the reaction [FGF2 protein results in increased expression of TP53 protein]increases expression|increases reaction 16351512
C006453 alliin alliin results in decreased secretion of FGF2 proteindecreases secretion 16351512
D000538 Aluminum Silicates Aluminum Silicates results in increased secretion of FGF2 proteinincreases secretion 16335828
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FGF2 mRNAaffects expression 16483693
D000661 Amphetamine Amphetamine results in increased expression of FGF2 proteinincreases expression 16338078
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [IL1A protein results in increased expression of FGF2 mRNA]decreases reaction|increases expression 12832416
D001149 Arsenates Arsenates results in increased expression of FGF2 mRNAincreases expression 15345372
C015001 arsenite arsenite results in increased expression of FGF2 mRNAincreases expression 15345372
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of FGF2 mRNAaffects expression 17331233
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of FGF2 mRNAincreases expression 18687144
D001205 Ascorbic Acid Ascorbic Acid promotes the reaction [alliin results in decreased activity of FGF2 protein]decreases activity|increases reaction 16351512
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of FGF2 mRNAincreases expression 19181443
C070515 bisindolylmaleimide I bisindolylmaleimide I inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 12403780
D002101 Cacodylic Acid Cacodylic Acid results in increased expression of FGF2 mRNAincreases expression 15345372
C058819 calphostin C calphostin C inhibits the reaction [FGF2 protein results in increased expression of and results in increased activity of RUNX2 protein]decreases reaction|increases activity|increases expression 12403780
C058819 calphostin C calphostin C inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 12403780
D002251 Carbon Tetrachloride FGF2 protein affects the susceptibility to Carbon Tetrachlorideaffects response to substance 14507672
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of FGF2 mRNAincreases expression 17158861
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of FGF2 proteinincreases expression 16116963
D002713 Chlorine Chlorine results in decreased expression of FGF2 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of FGF2 mRNAaffects cotreatment|affects expression 18636392
D004390 Chlorpyrifos Chlorpyrifos results in decreased expression of FGF2 mRNAdecreases expression 17589599
D002809 Chondroitin Sulfates Chondroitin Sulfates analog binds to FGF2 proteinaffects binding 12221095
D002809 Chondroitin Sulfates [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 proteinaffects binding 15385557
D002809 Chondroitin Sulfates [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 proteinaffects binding 14699094
C065927 cilnidipine cilnidipine results in decreased expression of FGF2 mRNAdecreases expression 16333380
D003008 Cloprostenol Cloprostenol results in increased expression of FGF2 mRNAincreases expression 14991729
D003024 Clozapine Clozapine results in increased expression of FGF2 mRNAincreases expression 11264663
D003513 Cycloheximide Cycloheximide inhibits the reaction [Dinoprost affects the localization of FGF2 protein]affects localization|decreases reaction 15654655
D003871 Dermatan Sulfate [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 proteinaffects binding 15385557
D003871 Dermatan Sulfate Dermatan Sulfate analog results in increased activity of FGF2 proteinincreases activity 15563459
D003871 Dermatan Sulfate [Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 proteinaffects binding 14699094
D003907 Dexamethasone Dexamethasone inhibits the reaction [nitrofen results in decreased expression of FGF2 mRNA]decreases expression|decreases reaction 10646786
D003976 Diazinon Diazinon results in decreased expression of FGF2 mRNAdecreases expression 19130878
17589599
D004026 Dieldrin Dieldrin results in decreased expression of FGF2 mRNAdecreases expression 19130878
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of FGF2 mRNAdecreases expression 17005392
D004280 Dobutamine FGF2 protein affects the susceptibility to Dobutamineaffects response to substance 14583313
D004280 Dobutamine FGF2 protein affects the susceptibility to Dobutamineaffects response to substance 10491406
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal results in increased expression of FGF2 mRNAincreases expression 16313111
C117757 E 5842 E 5842 results in decreased expression of FGF2 mRNAdecreases expression 11264663
C117757 E 5842 E 5842 results in increased expression of FGF2 mRNAincreases expression 11264663
C117757 E 5842 E 5842 results in increased expression of FGF2 proteinincreases expression 11264663
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of FGF2 mRNAdecreases expression 16084531
D004958 Estradiol Estradiol results in increased expression of FGF2 mRNAincreases expression 15367264
D004958 Estradiol Estradiol results in increased expression of FGF2 mRNAincreases expression 21098263
C024552 estrone benzoate estrone benzoate results in decreased expression of FGF2 mRNAdecreases expression 15120423
C024552 estrone benzoate Progesterone inhibits the reaction [estrone benzoate results in decreased expression of FGF2 mRNA]decreases expression|decreases reaction 15120423
D005047 Etoposide FGF2 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005472 Fluorouracil Fluorouracil results in decreased expression of FGF2 mRNAdecreases expression 16510598
D005576 Forskolin Forskolin results in increased expression of FGF2 mRNAincreases expression 10320526
D005576 Forskolin Forskolin results in increased expression of FGF2 proteinincreases expression 10320526
C070081 fulvestrant fulvestrant inhibits the reaction [FGF2 protein results in increased expression of CCND1 protein]decreases reaction|increases expression 20179196
D005665 Furosemide Furosemide results in decreased expression of FGF2 mRNAdecreases expression 16526316
D019833 Genistein Genistein results in decreased activity of FGF2 proteindecreases activity 10569980
D006025 Glycosaminoglycans Glycosaminoglycans results in increased activity of FGF2 proteinincreases activity 12659634
D006072 Gossypol Gossypol results in decreased expression of FGF2 mRNAdecreases expression 19825521
D006072 Gossypol zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGF2 mRNA]decreases expression|increases reaction 19825521
D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGF2 protein]affects localization|decreases reaction 15654655
D019812 Heparan Sulfate Proteoglycans [Heparan Sulfate Proteoglycans binds to and results in increased activity of FGF2 protein] which results in increased expression of TNFSF11 proteinaffects binding|increases activity|increases expression 15334457
D019812 Heparan Sulfate Proteoglycans [Heparan Sulfate Proteoglycans binds to FGF2 protein binds to FGFR1 protein] which binds to KAL1 proteinaffects binding 15548653
D019812 Heparan Sulfate Proteoglycans Heparan Sulfate Proteoglycans affects the reaction [FGF2 protein binds to FGFR1 protein]affects binding|affects reaction 10336501
D019812 Heparan Sulfate Proteoglycans Heparan Sulfate Proteoglycans affects the reaction [FGF2 protein binds to FGFR4 protein]affects binding|affects reaction 10336501
D019812 Heparan Sulfate Proteoglycans Heparan Sulfate Proteoglycans binds to FGF2 proteinaffects binding 8227197
D006493 Heparin Heparin promotes the reaction [FGF2 protein binds to FGFR1 protein]affects binding|increases reaction 12440867
D006493 Heparin Heparin results in decreased activity of FGF2 proteindecreases activity 10569980
15051888
D006493 Heparin Heparin binds to FGFR1 protein binds to FGF2 proteinaffects binding 15096041
D006493 Heparin Heparin promotes the reaction [FGFR1 protein binds to FGF2 protein]affects binding|increases reaction 1379594
D006493 Heparin Heparin promotes the reaction [FGFR2 protein binds to FGF2 protein]affects binding|increases reaction 1373495
D006493 Heparin Heparin affects the activity of FGF2 proteinaffects activity 15232299
D006493 Heparin Heparin affects the reaction [FGF2 protein binds to FGFR4 protein]affects binding|affects reaction 10336501
D006493 Heparin [Heparin binds to FGFR2 protein alternative form] which binds to FGF2 proteinaffects binding 10860838
D006493 Heparin Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of AKT1 protein]decreases reaction|increases phosphorylation 14966081
D006493 Heparin Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K1 protein]decreases reaction|increases phosphorylation 14966081
D006493 Heparin Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K2 protein]decreases reaction|increases phosphorylation 14966081
D006493 Heparin Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]decreases reaction|increases phosphorylation 14966081
D006493 Heparin Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]decreases reaction|increases phosphorylation 14966081
D006493 Heparin Heparin analog binds to and results in decreased degradation of FGF2 proteinaffects binding|decreases degradation 9174673
D006493 Heparin Heparin binds to FGF2 proteinaffects binding 7547864
15632177
D006493 Heparin Heparin promotes the reaction [FGF2 protein results in increased activity of FGFR1 protein]increases activity|increases reaction 12799194
D006493 Heparin Heparin results in increased activity of FGF2 proteinincreases activity 12799194
D006493 Heparin phosphomannopentaose sulfate inhibits the reaction [Heparin binds to FGF2 protein]affects binding|decreases reaction 15632177
D006497 Heparitin Sulfate Heparitin Sulfate binds to and affects the activity of FGF2 proteinaffects activity|affects binding 15958608
D006497 Heparitin Sulfate Heparitin Sulfate analog results in increased activity of FGF2 proteinincreases activity 12460940
D006497 Heparitin Sulfate Heparitin Sulfate binds to FGF2 proteinaffects binding 15464572
D006497 Heparitin Sulfate Heparitin Sulfate analog binds to FGF2 proteinaffects binding 14707131
15081013
D006583 Hexadimethrine Hexadimethrine results in decreased activity of FGF2 proteindecreases activity 10569980
C482862 heyneanol A heyneanol A results in decreased activity of FGF2 proteindecreases activity 16675471
D006851 Hydrochloric Acid Hydrochloric Acid results in decreased expression of FGF2 mRNAdecreases expression 15046208
D006861 Hydrogen Peroxide Hydrogen Peroxide promotes the reaction [FGF2 protein binds to FGFR1 protein]affects binding|increases reaction 8849686
D016285 Iloprost Iloprost results in increased expression of FGF2 mRNAincreases expression 16373414
D016285 Iloprost tyrphostin AG 1478 inhibits the reaction [Iloprost results in increased expression of FGF2 mRNA]decreases reaction|increases expression 16373414
C056493 imiquimod imiquimod results in decreased expression of FGF2decreases expression 16368197
C056493 imiquimod imiquimod results in decreased expression of FGF2decreases expression 16302556
D007213 Indomethacin Indomethacin inhibits the reaction [FGF2 protein results in increased expression of CCND1 protein]decreases reaction|increases expression 11170841
D007213 Indomethacin Indomethacin inhibits the reaction [FGF2 protein results in increased expression of CCNE1 protein]decreases reaction|increases expression 11170841
D007213 Indomethacin Indomethacin inhibits the reaction [FGF2 protein results in increased phosphorylation of RB1 protein]decreases reaction|increases phosphorylation 11170841
D007213 Indomethacin Indomethacin results in increased expression of FGF2 mRNAincreases expression 17440234
C051890 irinotecan irinotecan metabolite results in increased expression of FGF2 mRNAincreases expression 15956246
C051890 irinotecan irinotecan results in increased expression of FGF2 mRNAincreases expression 15956246
D007608 Kainic Acid Kainic Acid results in increased expression of FGF2 mRNAincreases expression 7649223
D008628 Mercury Mercury results in increased expression of FGF2 mRNAincreases expression 16823088
C008493 methylselenic acid methylselenic acid results in decreased expression of FGF2 mRNAdecreases expression 12517777
C020300 monomethylarsonic acid monomethylarsonic acid results in increased expression of FGF2 mRNAincreases expression 15345372
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FGF2 protein results in increased expression of BDNF mRNA]decreases reaction|increases expression 16269011
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FGF2 protein results in increased expression of NTRK2 mRNA]decreases reaction|increases expression 16269011
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FGF2 protein results in increased phosphorylation of CREB1 protein]decreases reaction|increases phosphorylation 16269011
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]decreases reaction|increases phosphorylation 16269011
D009532 Nickel Nickel results in decreased expression of FGF2 mRNAdecreases expression 19130878
D009538 Nicotine Nicotine results in increased secretion of FGF2 proteinincreases secretion 16365874
D009538 Nicotine Nicotine results in decreased expression of FGF2 proteindecreases expression 14732461
D009538 Nicotine Nicotine results in increased expression of FGF2 mRNAincreases expression 15465631
D009538 Nicotine Nicotine results in increased expression of FGF2 proteinincreases expression 15465631
D009543 Nifedipine Nifedipine inhibits the reaction [FGF2 protein results in increased expression of FOS mRNA]decreases reaction|increases expression 16188231
C007350 nitrofen Dexamethasone inhibits the reaction [nitrofen results in decreased expression of FGF2 mRNA]decreases expression|decreases reaction 10646786
C007350 nitrofen nitrofen results in decreased expression of FGF2 mRNAdecreases expression 10646786
10898222
D026423 S-Nitroso-N-Acetylpenicillamine S-Nitroso-N-Acetylpenicillamine promotes the reaction [FGF2 protein results in increased expression of TP53 protein]increases expression|increases reaction 16351512
D009844 Oligosaccharides Oligosaccharides binds to and results in decreased degradation of FGF2 proteinaffects binding|decreases degradation 9174673
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of FGF2 mRNAaffects cotreatment|affects expression 18636392
C002669 parthenolide parthenolide inhibits the reaction [FGF2 protein results in increased activity of [NFKB1 protein binds to RELA protein]]affects binding|decreases reaction|increases activity 16921510
C002669 parthenolide parthenolide inhibits the reaction [FGF2 protein results in increased expression of TRAF1 mRNA]decreases reaction|increases expression 16921510
C002669 parthenolide parthenolide inhibits the reaction [FGF2 protein results in increased expression of TRAF2 mRNA]decreases reaction|increases expression 16921510
C093973 PD 98059 PD 98059 inhibits the reaction [FGF2 protein results in increased activity of HIF1A protein]decreases reaction|increases activity 15631803
C093973 PD 98059 PD 98059 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]decreases reaction|increases phosphorylation 15631803
C093973 PD 98059 PD 98059 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]decreases reaction|increases phosphorylation 15631803
C093973 PD 98059 PD 98059 inhibits the reaction [FGF2 protein results in increased expression of PLAU mRNA]decreases reaction|increases expression 9442043
C093973 PD 98059 PD 98059 inhibits the reaction [FGF2 protein results in increased expression of BDNF mRNA]decreases reaction|increases expression 16269011
C093973 PD 98059 PD 98059 inhibits the reaction [FGF2 protein results in increased phosphorylation of CREB1 protein]decreases reaction|increases phosphorylation 16269011
C093973 PD 98059 PD 98059 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]decreases reaction|increases phosphorylation 16269011
D010656 Phenylephrine Phenylephrine promotes the reaction [EGR1 protein binds to FGF2 promoter]affects binding|increases reaction 10779383
C120158 phosphomannopentaose sulfate phosphomannopentaose sulfate analog binds to FGF2 proteinaffects binding 16366604
C120158 phosphomannopentaose sulfate phosphomannopentaose sulfate binds to FGF2 proteinaffects binding 16366604
C120158 phosphomannopentaose sulfate phosphomannopentaose sulfate inhibits the reaction [Heparin binds to FGF2 protein]affects binding|decreases reaction 15632177
C025299 polyphenols polyphenols results in decreased expression of FGF2 mRNAdecreases expression 16293270
D011374 Progesterone Progesterone inhibits the reaction [estrone benzoate results in decreased expression of FGF2 mRNA]decreases expression|decreases reaction 15120423
D015237 Dinoprost 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGF2 protein]affects localization|decreases reaction 15654655
D015237 Dinoprost Cycloheximide inhibits the reaction [Dinoprost affects the localization of FGF2 protein]affects localization|decreases reaction 15654655
D015237 Dinoprost Dinoprost affects the localization of FGF2 proteinaffects localization 15654655
D015237 Dinoprost Dinoprost affects the localization of [FGF2 protein binds to FGFR2 protein]affects binding|affects localization 16365892
D015237 Dinoprost Dinoprost promotes the reaction [FGF2 protein binds to FGFR2 protein]affects binding|increases reaction 16365892
D015237 Dinoprost Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGF2 protein]affects localization|decreases reaction 15654655
C059514 resveratrol resveratrol results in decreased expression of FGF2 mRNAdecreases expression 17935668
C059514 resveratrol resveratrol results in decreased expression of FGF2 proteindecreases expression 17935668
C059514 resveratrol resveratrol results in decreased activity of FGF2 proteindecreases activity 16675471
C085746 rottlerin rottlerin inhibits the reaction [FGF2 protein results in increased activity of RUNX2 protein]decreases reaction|increases activity 12403780
C085746 rottlerin rottlerin inhibits the reaction [FGF2 protein results in increased expression of RUNX2 mRNA]decreases reaction|increases expression 12403780
C079198 S 1 (combination) S 1 (combination) results in decreased expression of FGF2 mRNAdecreases expression 18607998
C093642 SB 203580 SB 203580 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK14 protein]decreases reaction|increases phosphorylation 15631803
C093642 SB 203580 SB 203580 inhibits the reaction [FGF2 protein results in increased phosphorylation of RB1 protein]decreases reaction|increases phosphorylation 15249425
C093642 SB 203580 SB 203580 results in decreased activity of FGF2 proteindecreases activity 15249425
C484876 scutellarin scutellarin results in decreased expression of FGF2 proteindecreases expression 16297343
C440975 silybin silybin inhibits the reaction [Urethane results in increased secretion of FGF2 protein]decreases reaction|increases secretion 16788158
C017947 sodium arsenite sodium arsenite results in decreased expression of FGF2 mRNAdecreases expression 19615344
C017947 sodium arsenite sodium arsenite results in increased expression of FGF2 mRNAincreases expression 12703962
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased expression of and results in increased activity of HIF1A protein]decreases reaction|increases activity|increases expression 15631803
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased expression of FOS mRNA]decreases reaction|increases expression 16188231
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased expression of TACR1 mRNA alternative form]decreases reaction|increases expression 16154193
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased phosphorylation of AKT1 protein]decreases reaction|increases phosphorylation 15631803
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK14 protein]decreases reaction|increases phosphorylation 15631803
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]decreases reaction|increases phosphorylation 15631803
C105686 SU 5402 SU 5402 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]decreases reaction|increases phosphorylation 15631803
C105686 SU 5402 SU 5402 results in decreased expression of FGF2 mRNAdecreases expression 12421715
C105686 SU 5402 SU 5402 results in increased expression of FGF2 mRNAincreases expression 12421715
C105686 SU 5402 SU 5402 results in decreased activity of FGF2 proteindecreases activity 12076337
D013498 Suramin Suramin results in increased expression of FGF2increases expression 8394679
D014284 Triiodothyronine Triiodothyronine inhibits the reaction [FGF2 protein results in increased phosphorylation of STAT1 protein]decreases reaction|increases phosphorylation 16150908
D014284 Triiodothyronine Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]increases phosphorylation|increases reaction 16150908
D014284 Triiodothyronine Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]increases phosphorylation|increases reaction 16150908
D014284 Triiodothyronine Triiodothyronine promotes the reaction [FGF2 protein promotes the reaction [FGFR1 protein results in increased phosphorylation of FGFR1 protein]]increases phosphorylation|increases reaction 12805413
D014284 Triiodothyronine Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]increases activity|increases phosphorylation|increases reaction 12805413
D014284 Triiodothyronine Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]increases activity|increases phosphorylation|increases reaction 12805413
D013629 Tamoxifen FGF2 protein results in decreased susceptibility to Tamoxifendecreases response to substance 20179196
D013629 Tamoxifen Tamoxifen inhibits the reaction [FGF2 protein results in increased expression of CCND1 protein]decreases reaction|increases expression 20179196
C047246 temozolomide [temozolomide co-treated with Thalidomide] results in decreased expression of FGF2 proteinaffects cotreatment|decreases expression 16327979
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of FGF2 mRNAincreases expression 12377990
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of FGF2 mRNAaffects expression 12167310
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased secretion of FGF2 proteinincreases secretion 11874475
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGF2 protein]affects localization|decreases reaction 15654655
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter]affects binding|increases reaction 10779383
D013792 Thalidomide Thalidomide affects the expression of FGF2 mRNAaffects expression 15939924
D013792 Thalidomide Thalidomide affects the expression of FGF2 proteinaffects expression 15939924
D013792 Thalidomide Thalidomide affects the secretion of FGF2 proteinaffects secretion 15939924
D013792 Thalidomide [temozolomide co-treated with Thalidomide] results in decreased expression of FGF2 proteinaffects cotreatment|decreases expression 16327979
D024505 Tocopherols Tocopherols results in decreased expression of FGF2 mRNAdecreases expression 15878867
D019772 Topotecan FGF2 protein affects the susceptibility to Topotecanaffects response to substance 16217747
D014107 Tosyllysine Chloromethyl Ketone Tosyllysine Chloromethyl Ketone inhibits the reaction [FGF2 protein results in increased expression of NRP1 mRNA]decreases reaction|increases expression 16289960
D014212 Tretinoin FGF2 protein promotes the reaction [Tretinoin results in increased expression of GAB2 protein]increases expression|increases reaction 16009726
D014212 Tretinoin FGF2 protein promotes the reaction [Tretinoin results in increased expression of TUBB3 protein]increases expression|increases reaction 16009726
D014212 Tretinoin FGF2 protein results in decreased susceptibility to Tretinoindecreases response to substance 16009726
D014212 Tretinoin GAB2 protein promotes the reaction [FGF2 protein results in decreased susceptibility to Tretinoin]decreases response to substance|increases reaction 16009726
D014269 Trifluoroacetic Acid Acrylamide analog inhibits the reaction [Trifluoroacetic Acid results in increased degradation of FGF2 protein]decreases reaction|increases degradation 14733594
C101044 tyrphostin AG 1478 tyrphostin AG 1478 inhibits the reaction [Iloprost results in increased expression of FGF2 mRNA]decreases reaction|increases expression 16373414
C113580 U 0126 U 0126 inhibits the reaction [FGF2 protein results in increased expression of NRP1 mRNA]decreases reaction|increases expression 16289960
C113580 U 0126 U 0126 inhibits the reaction [FGF2 protein results in increased expression of BDNF mRNA]decreases reaction|increases expression 16269011
D014520 Urethane silybin inhibits the reaction [Urethane results in increased secretion of FGF2 protein]decreases reaction|increases secretion 16788158
D014520 Urethane Urethane results in increased secretion of FGF2 proteinincreases secretion 16788158
C066075 vanadium pentoxide vanadium pentoxide results in decreased expression of FGF2 mRNAdecreases expression 17459161
D014810 Vitamin E Vitamin E promotes the reaction [alliin results in decreased activity of FGF2 protein]decreases activity|increases reaction 16351512
C009687 wortmannin wortmannin inhibits the reaction [[FGF2 protein binds to and results in increased activity of FGFR4 protein] which results in increased phosphorylation of MAPK1 protein]affects binding|decreases reaction|increases activity|increases phosphorylation 11336793
C088658 zoledronic acid zoledronic acid promotes the reaction [Gossypol results in decreased expression of FGF2 mRNA]decreases expression|increases reaction 19825521
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6314745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 5.7915322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 5.798333272
MESH:D000038 Abscess Drugs, Chinese Herbal 5.4015043669
MESH:D000138 Acidosis Ammonium Chloride 7.7718287403
MESH:D000138 Acidosis Hydrochloric Acid 7.7711574821 19262391 16144966 12771618 15920416 20872349
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 4.8917183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 4.9020597076
MESH:D000168 Acrocephalosyndactylia U 0126 4.6017694057
MESH:D058186 Acute Kidney Injury resveratrol 6.3816538975
MESH:D058186 Acute Kidney Injury zoledronic acid 6.3819715164
MESH:D055371 Acute Lung Injury Chlorine 10.8220601635
MESH:D055371 Acute Lung Injury Hydrochloric Acid 10.8211850527 19094174 15970105 11953099 19760209 19060228 16759491
MESH:D055371 Acute Lung Injury Nickel 10.8216166738
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.5820200999
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.5920127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 12.5911473722
MESH:D000230 Adenocarcinoma Fluorouracil 12.5917638652
MESH:D000230 Adenocarcinoma Genistein 12.5911473722
MESH:D000230 Adenocarcinoma Indomethacin 12.5916537180
MESH:D000230 Adenocarcinoma Urethane 12.5918316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.8015814487
MESH:D000236 Adenoma Benzo(a)pyrene 11.106695378
MESH:D000236 Adenoma Indomethacin 11.1011497255
MESH:D000236 Adenoma resveratrol 11.1015688382
MESH:D000236 Adenoma Urethane 11.106695378 17195641 16926031 10530776 10822126 11497255 17093202
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 2.4916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7915276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 3.9916712894 17306315
MESH:D000380 Agranulocytosis Clozapine 4.1814617031 16160616 12649775
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 6.2511874814 16611668 17119214
MESH:D000382 Agricultural Workers' Diseases Diazinon 6.2516487989
MESH:D000505 Alopecia Tretinoin 2.8715955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.4617225004
MESH:D000544 Alzheimer Disease Indomethacin 6.8517627676 15579461
MESH:D000544 Alzheimer Disease Nicotine 6.8516627626
MESH:D000544 Alzheimer Disease Ozone 6.8515513908
MESH:D000544 Alzheimer Disease resveratrol 6.8516162502 16183991
MESH:D019969 Amphetamine-Related Disorders Amphetamine 5.1618475255 15010207 16459022 16916582
MESH:D000686 Amyloidosis Diethylstilbestrol 3.6215469931
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 3.7316510725
MESH:D000740 Anemia Drugs, Chinese Herbal 10.3417963324 15504547
MESH:D000740 Anemia Fluorouracil 10.3416511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 10.3411748828
MESH:D000787 Angina Pectoris Drugs, Chinese Herbal 4.5111477813
MESH:D000855 Anorexia Amphetamine 4.2112005258 16101753 16084549 12183048
MESH:D000860 Anoxia Hydrochloric Acid 4.4115090967
MESH:D001004 Anus Diseases Drugs, Chinese Herbal 5.0515043669
MESH:D001014 Aortic Aneurysm Indomethacin 3.9910231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 8.8019183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 8.8010388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.3217460149
MESH:D018771 Arthralgia Indomethacin 4.262160914
MESH:D001169 Arthritis, Experimental Dexamethasone 12.4417659584
MESH:D001169 Arthritis, Experimental resveratrol 12.4417115116
MESH:D001169 Arthritis, Experimental Thalidomide 12.449598899
MESH:D001169 Arthritis, Experimental Tretinoin 12.4416412693
MESH:D015210 Arthritis, Gouty Drugs, Chinese Herbal 4.8519655406
MESH:D001172 Arthritis, Rheumatoid Indomethacin 5.5511248219
MESH:D001172 Arthritis, Rheumatoid Ozone 5.5515570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 5.5516292516
MESH:D001249 Asthma epigallocatechin gallate 5.7516516891
MESH:D001249 Asthma Ozone 5.7516373670 17854713
MESH:D001249 Asthma Tretinoin 5.7516456186
MESH:D001254 Astrocytoma temozolomide 5.5915865885
MESH:D050197 Atherosclerosis resveratrol 2.6917967414 16873680
MESH:D001284 Atrophy fulvestrant 3.9911514358
MESH:D001321 Autistic Disorder Mercury 2.9817497416
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 8.3419761891
MESH:D001327 Autoimmune Diseases Mercury 8.3416634805
MESH:D001471 Barrett Esophagus Tretinoin 3.5416935849
MESH:D001477 Bartter Syndrome Indomethacin 4.1010684365
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 10.7915920416
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 10.7912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 10.7916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1215746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 4.2514601052
MESH:D001859 Bone Neoplasms zoledronic acid 4.1219442620 15867366 11697798 17312309 16121404 16778634
MESH:D001862 Bone Resorption Drugs, Chinese Herbal 7.449881647
MESH:D001862 Bone Resorption zoledronic acid 7.4418404659 8053405 16769263 18496637 15845617 11869084
MESH:D001913 Bowen's Disease imiquimod 5.5311207687
MESH:D001919 Bradycardia Phenylephrine 3.6615306635
MESH:D001929 Brain Edema Indomethacin 4.1111481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.4217868700
MESH:D001930 Brain Injuries Progesterone 3.3815665606 15845082 15380490
MESH:D002545 Brain Ischemia Indomethacin 12.2412524144
MESH:D002545 Brain Ischemia resveratrol 12.2417600658
MESH:D002545 Brain Ischemia scutellarin 12.2416297343
MESH:D001943 Breast Neoplasms Acrylamide 18.8018183576 16253758
MESH:D001943 Breast Neoplasms Ascorbic Acid 18.8016443354
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 18.8017474063 20146248
MESH:D001943 Breast Neoplasms Cacodylic Acid 18.8017474063
MESH:D001943 Breast Neoplasms Dieldrin 18.8011859874 15770527
MESH:D001943 Breast Neoplasms Diethylstilbestrol 18.8015324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 18.8016675129 12948864 17261762 17289903 14630087 17018787 19861407 18497071
MESH:D001943 Breast Neoplasms Etoposide 18.8016322251
MESH:D001943 Breast Neoplasms Fluorouracil 18.8016110121 15136595 18357371 19217205 16557594 16595493 18608205
MESH:D001943 Breast Neoplasms fulvestrant 18.8018984771
MESH:D001943 Breast Neoplasms Genistein 18.8017200150 16873071 16541309
MESH:D001943 Breast Neoplasms Indomethacin 18.8017401462
MESH:D001943 Breast Neoplasms Nickel 18.8015986119
MESH:D001943 Breast Neoplasms parthenolide 18.8016873071
MESH:D001943 Breast Neoplasms Progesterone 18.8015562024 17614352 16175315
MESH:D001943 Breast Neoplasms resveratrol 18.8016393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 18.8019155303 21138602 18629630 19066611 19189210 17049068 20135344 20005174 18855134 20390343 20544844 16818667 19221464 20065188 11161223 17242785 18815881 21152245 17893378 19289846 15565566 19244106 16202921 18821012 19189212 17440819 19115204 19142967 18351453 18425577 19011961 19103187 19288272 19059307 20859285 17261762 15668708 19410462 19084267 19200415 18984771 16273361 16873071 18997820 19487384
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 18.8020435547
MESH:D001943 Breast Neoplasms Tretinoin 18.8016166294 16443354 16873071
MESH:D001943 Breast Neoplasms zoledronic acid 18.8018695136 16096432
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 10.1812378975
MESH:D016535 Bronchial Hyperreactivity Ozone 10.1815516495 16777450 18315731 17626835 18417511 19059883 14754758
MESH:D016535 Bronchial Hyperreactivity tyrphostin AG 1478 10.1812794006
MESH:D001986 Bronchial Spasm Hydrochloric Acid 4.5615578804
MESH:D001991 Bronchitis vanadium pentoxide 5.3217459161
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.6916813970
MESH:D002056 Burns Indomethacin 3.8310459503
MESH:D002100 Cachexia Indomethacin 9.4315625704 16537180 11239499 15141370
MESH:D002100 Cachexia Ozone 9.4316183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5716111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 7.0415721981 3786805 15673190 16011737 16227642 10355542 15700767 16192424 16124888 16050911 16097048 18705752
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 7.0416050911
MESH:D002276 Carcinoid Tumor Fluorouracil 3.7616051944
MESH:D002277 Carcinoma Fluorouracil 5.7217121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 5.7216835633
MESH:D002280 Carcinoma, Basal Cell imiquimod 4.5816302556
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.6319066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.2416168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 25.4816705839
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 25.4819418558
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 25.4818788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 25.4816924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 25.4816924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 25.4816799960 16332177 17971768 17045692 17088986 18930000
MESH:D006528 Carcinoma, Hepatocellular Genistein 25.4816924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 25.4816391822
MESH:D006528 Carcinoma, Hepatocellular resveratrol 25.4816227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 25.4817306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 25.4816924424
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 25.4816313753
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 25.481917145
MESH:D018827 Carcinoma, Lewis Lung heyneanol A 14.1916675471
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 14.1911053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 14.1916675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.4514736730 11352223 18791128
MESH:D002289 Carcinoma, Non-Small-Cell Lung S 1 (combination) 4.9518212800 18347146
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 4.9519233551
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 7.9118695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 7.9117341418
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 7.9118507039
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 26.0417015178
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 26.0420419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 26.0418986760 16280240 17066447 16757204
MESH:D002294 Carcinoma, Squamous Cell imiquimod 26.0416302556
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 26.0412636206 15482327
MESH:D002294 Carcinoma, Squamous Cell resveratrol 26.0416227395
MESH:D002294 Carcinoma, Squamous Cell S 1 (combination) 26.0415984520
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 26.0418572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 26.0418922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 26.0416096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 2.8217572228
MESH:D006332 Cardiomegaly marker/mechanism 10491406
MESH:D006332 Cardiomegaly cilnidipine 8.4016333380
MESH:D006332 Cardiomegaly Phenylephrine 8.4017124262 16170337 15728586 11179087 11754973 17287366
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 8.4018850075 16120746 18670907
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.0510334427
MESH:D002318 Cardiovascular Diseases Genistein 8.3316332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 8.3316936243
MESH:D002318 Cardiovascular Diseases resveratrol 8.3315458977
MESH:D002386 Cataract Tretinoin 2.4917460283
MESH:D002418 Cattle Diseases Acrylamide 4.5412510666
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 14.036135515
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 14.0318226522
MESH:D002471 Cell Transformation, Neoplastic Dinoprost 14.0316192471
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.0318566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 14.0319524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.6916129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.1716835633
MESH:D018281 Cholangiocarcinoma Thalidomide 7.1718291259
MESH:D002764 Cholecystitis Indomethacin 4.2611181007
MESH:D002822 Choriocarcinoma Tretinoin 4.2416461808
MESH:D002971 Cleft Lip marker/mechanism 17963255
MESH:D002972 Cleft Palate marker/mechanism 17963255
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.0912621046 8697196 16354765 15668235 15340226
MESH:D002972 Cleft Palate Tretinoin 7.099407595
MESH:D002972 Cleft Palate Urethane 7.0912810352
MESH:D003072 Cognition Disorders Clozapine 4.0917123785
MESH:D003092 Colitis resveratrol 11.1616474422
MESH:D003092 Colitis Thalidomide 11.1616680017
MESH:D003092 Colitis Tretinoin 11.1617035595
MESH:D003110 Colonic Neoplasms arsenite 15.5815037631
MESH:D003110 Colonic Neoplasms Dexamethasone 15.5815824018
MESH:D003110 Colonic Neoplasms Fluorouracil 15.5817287894 15001691 17725105 17169374 17016597 18772588 16510598 17172411 17018589 16340194
MESH:D003110 Colonic Neoplasms Genistein 15.5817182828
MESH:D003110 Colonic Neoplasms Indomethacin 15.5815637740 15936596 15625704 15786552 15963497 11260862
MESH:D003110 Colonic Neoplasms irinotecan 15.5817725105 17287894
MESH:D003110 Colonic Neoplasms polyphenols 15.5816293270
MESH:D003110 Colonic Neoplasms resveratrol 15.5816338953
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.6417016601 16331619 17094418 20501625 18288408 18802399 18949393 15148649 17594712 17401013 18448328 17454858 15289873 18509181 17255274 16303861 14970324 16282729 16391804 18383874 17695437 16524972
MESH:D015179 Colorectal Neoplasms Indomethacin 3.6412606626 11197048 18059344 17054584
MESH:D015179 Colorectal Neoplasms irinotecan 3.6417454858 18259882 18509181 16391804 16303861 17159606 15273666
MESH:D015179 Colorectal Neoplasms resveratrol 3.6416550006
MESH:D003139 Common Cold Ascorbic Acid 4.5617323712
MESH:D003218 Condylomata Acuminata imiquimod 6.2216302556 11362904
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.2814669216 17141729
MESH:D016510 Corneal Neovascularization marker/mechanism 9301478
MESH:D016510 Corneal Neovascularization Thalidomide 4.699301478
MESH:D003327 Coronary Disease resveratrol 3.1116507316
MESH:D018352 Coronavirus Infections Indomethacin 4.8017302372
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.399200351
MESH:D019465 Craniofacial Abnormalities Dexamethasone 7.1317728286
MESH:D019465 Craniofacial Abnormalities nitrofen 7.1311405365
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.1310048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Thalidomide 7.139200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 7.138800419 10589399 9125849 16925845 9224671 17551590 14991402 9664655 9142499 9211117
MESH:D019465 Craniofacial Abnormalities Vitamin E 7.1319769572
MESH:D003424 Crohn Disease Thalidomide 3.6416078585
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.7016002989 12952375
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.1418551238
MESH:D003550 Cystic Fibrosis Acetylcysteine 3.5919747007
MESH:D003556 Cystitis Hydrochloric Acid 4.5620719367 12599022 12853844 19279288
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 4.9017714534
MESH:D007644 Darier Disease Fluorouracil 3.8916733453
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4819031437
MESH:D003866 Depressive Disorder marker/mechanism 16861106
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 6.9512438553
MESH:D017449 Dermatitis, Allergic Contact Mercury 6.9516823706
MESH:D017449 Dermatitis, Allergic Contact Nickel 6.9519470301 17100760 17244072
MESH:D003877 Dermatitis, Contact Nickel 3.812952479
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.0216873680
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 10.0216506275
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 10.0216402076
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 10.0216988119
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 10.0216647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 10.0217107852
MESH:D003928 Diabetic Nephropathies Estradiol 10.5319279558
MESH:D003928 Diabetic Nephropathies resveratrol 10.5316286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.5319279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.6117187935
MESH:D003967 Diarrhea Dexamethasone 5.497237001
MESH:D003967 Diarrhea Indomethacin 5.497237001 7907874
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.6415331141
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 12.7518551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 12.7511287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.7516177239 11566570 16227642 3732212 7440962 7179309 21278145 2869522 19085960 15027814 10915739 10092053 15968718 19336974 9327722 6884620 7120509 4309450 15998439 6623471 17522070 3786805
MESH:D056486 Drug-Induced Liver Injury Drugs, Chinese Herbal 12.7515027814
MESH:D056486 Drug-Induced Liver Injury polyphenols 12.7519370779
MESH:D056486 Drug-Induced Liver Injury scutellarin 12.7515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.7520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.0611462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.2518446180 16133044 16326151 12774134 18043480 17190690
MESH:D004381 Duodenal Ulcer Indomethacin 3.2917151854 17202747 11535926 11595415 17329845 11595431 17045617 17351913 16699067 10671773 11991626
MESH:D004387 Dupuytren Contracture imiquimod 5.8716368197
MESH:D050171 Dyslipidemias Clozapine 3.4916402076
MESH:D004417 Dyspnea Chlorine 12.1720016425
MESH:D004417 Dyspnea Diazinon 12.1716487989
MESH:D004417 Dyspnea Furosemide 12.1716935035
MESH:D020821 Dystonic Disorders Nicotine 5.0317881519
MESH:C538011 Eales disease Ascorbic Acid 10.049068938
MESH:C538011 Eales disease Vitamin E 10.049068938
MESH:D004485 Eczema Dexamethasone 3.6012438553
MESH:D004487 Edema bisindolylmaleimide I 20.428273558
MESH:D004487 Edema Dexamethasone 20.4219703484
MESH:D004487 Edema Furosemide 20.4211834646
MESH:D004487 Edema Indomethacin 20.4219703484 8273558 8985016 7990266 10653021 7907874 16100529
MESH:D004487 Edema resveratrol 20.428985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 20.4212711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 20.4211698051 8273558 16716910 8113982 15177302 7812673 9599246
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 8.9216714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 8.9218230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 10.5217692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 10.5217872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.5219031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 8.9216402032
MESH:D004714 Endometrial Hyperplasia Genistein 8.9216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 16.4315700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 16.4319148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 16.4311473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 16.4320544844 16202921 17893378 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 16.4316569247
MESH:D004715 Endometriosis Indomethacin 10.7015652904
MESH:D004715 Endometriosis Progesterone 10.7016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 10.709294722 10568697
MESH:D019446 Endotoxemia Indomethacin 3.6118509659
MESH:D004751 Enteritis Indomethacin 3.8410567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 9.4617980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 9.4617923197
MESH:D004802 Eosinophilia Indomethacin 3.2011298111
MESH:D004935 Esophageal Diseases Hydrochloric Acid 4.9019566590
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 5.3016530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 5.3015173087 16337965 17638652 16785472 16481741
MESH:D004938 Esophageal Neoplasms Indomethacin 5.3011005569
MESH:D004941 Esophagitis Hydrochloric Acid 5.1012928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.1011346197 14621274 20516732
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.4511564622
MESH:D005124 Eye Abnormalities Tretinoin 6.459664655 16938888
MESH:D005221 Fatigue Amphetamine 4.7019890266
MESH:D005234 Fatty Liver arsenite 8.5718296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 8.5712631006 61145 15959796 19224547 12795759 16239168 17595544 16045604
MESH:D005234 Fatty Liver Tamoxifen 8.5719224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.1216534752 16611131 16002989 16513791 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.1216709447
MESH:D005264 Femoral Fractures zoledronic acid 4.9316234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5811858732
MESH:D005334 Fever Dinoprost 7.2711852909
MESH:D005334 Fever Indomethacin 7.2710431976 11852909 17627676
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.6314745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.2919069698
MESH:D005354 Fibrosarcoma Indomethacin 4.0010962813
MESH:D005355 Fibrosis arsenite 23.3618296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.3618705752
MESH:D005355 Fibrosis Hydrochloric Acid 23.3618497604
MESH:D005355 Fibrosis Indomethacin 23.3617994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.3620067830
MESH:D005355 Fibrosis Tretinoin 23.3617994277
MESH:D005499 Folliculitis Indomethacin 4.2611298111
MESH:D005706 Gallbladder Neoplasms S 1 (combination) 4.9019093184
MESH:D005739 Gas Poisoning Chlorine 9.1020016425
MESH:D005739 Gas Poisoning Hydrochloric Acid 9.1012378975
MESH:D005756 Gastritis Indomethacin 3.8415046732
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.4720516732 19957777 20545468 20616304 19951613 12212954
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 9.8416452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 9.8416452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.3912701121
MESH:D005909 Glioblastoma Genistein 11.7016598420
MESH:D005909 Glioblastoma Indomethacin 11.7012870263
MESH:D005909 Glioblastoma temozolomide 11.7015865885
MESH:D005909 Glioblastoma Tretinoin 11.7017312396
MESH:D005910 Glioma Fluorouracil 10.3916145905
MESH:D005910 Glioma Indomethacin 10.3916487511 18371953
MESH:D005910 Glioma temozolomide 10.3910871815 16327979
MESH:D005910 Glioma Thalidomide 10.3916327979
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.5411849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6810696789
MESH:D006073 Gout Indomethacin 4.4511248219
MESH:D017789 Granuloma, Pyogenic imiquimod 6.2216302556
MESH:D006258 Head and Neck Neoplasms Fluorouracil 13.0515162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 13.0515482327
MESH:D006258 Head and Neck Neoplasms S 1 (combination) 13.0515984520 18607998
MESH:D006258 Head and Neck Neoplasms Tretinoin 13.0516096774
MESH:D034381 Hearing Loss Furosemide 4.0517868369
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.2416084493
MESH:D006356 Heartburn Hydrochloric Acid 4.9019566590
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 18.9616080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 18.9620471113
MESH:D006330 Heart Defects, Congenital nitrofen 18.9616080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 18.9610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 18.969664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin E 18.9616080930
MESH:D006331 Heart Diseases Urethane 3.5716046796
MESH:D006333 Heart Failure Dobutamine 5.9317440445
MESH:D006333 Heart Failure Furosemide 5.9312660669 16011733 16845234
MESH:D006391 Hemangioma imiquimod 5.8716302556
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5211000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.7515633222
MESH:D006505 Hepatitis Carbon Tetrachloride 11.0319900420 19110552
MESH:D006505 Hepatitis Diazinon 11.0316487989
MESH:D006505 Hepatitis Drugs, Chinese Herbal 11.0318339527
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.8215135802
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.0416120746 12621046 15340226
MESH:D006548 Hernia, Diaphragmatic marker/mechanism 10646786
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 10.1616863852 16490937
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 10.167520565
MESH:D006548 Hernia, Diaphragmatic nitrofen 10.1611588001 9575882 12547725 11685700 16473863 17270546 16080930 10370017 10541330 15707848 16292651 11076806 9473106 15793718 9476886 10898222 18280291 17245593 17618886 10646786 12746050 12505043 7576705 18280292 16863852 8863223 15764645 18958481 11051153 10370016 10359170 10898224 11409163 7520565 15136996 11584395 12407540 15185205 12021965 11057544 12194112 12904592 15088113 11329586 15578192 16720372 7760232 15756563 16490937 9859898 9698600 10693666 12759764
MESH:D006548 Hernia, Diaphragmatic Vitamin E 10.1616490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.1215709030
MESH:D006561 Herpes Simplex Etoposide 11.6810809021
MESH:D006561 Herpes Simplex phosphomannopentaose sulfate 11.6816366604
MESH:D006561 Herpes Simplex resveratrol 11.6816876885
MESH:D015658 HIV Infections Nickel 3.2817263646
MESH:D006689 Hodgkin Disease Etoposide 5.1216135485 17606976 15147373 16200630 18180244
MESH:D006689 Hodgkin Disease sodium arsenite 5.1212676792
MESH:D019584 Hot Flashes Estradiol 7.0417088409
MESH:D019584 Hot Flashes Vitamin E 7.0414716179
MESH:D018327 Hutchinson's Melanotic Freckle imiquimod 6.2216302556
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.1316959395 8697196 16354765 15340226 18606429
MESH:D006930 Hyperalgesia Indomethacin 9.0112727271
MESH:D006930 Hyperalgesia Tretinoin 9.0116870215
MESH:D006930 Hyperalgesia zoledronic acid 9.0116769263
MESH:D034321 Hyperamylasemia Indomethacin 4.8017883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6316899240
MESH:D006934 Hypercalcemia Furosemide 8.5817652376
MESH:D006934 Hypercalcemia zoledronic acid 8.5819622757 18089816
MESH:D053565 Hypercalciuria Furosemide 4.7517652376
MESH:D006937 Hypercholesterolemia resveratrol 3.2017188708
MESH:D006940 Hyperemia Hydrochloric Acid 9.7612646421
MESH:D006940 Hyperemia Indomethacin 9.7612524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.6916778211
MESH:D006948 Hyperkinesis Amphetamine 8.831977408 14960337
MESH:D006948 Hyperkinesis Clozapine 8.8316046005
MESH:D006949 Hyperlipidemias Indomethacin 6.7317546600
MESH:D006949 Hyperlipidemias resveratrol 6.7316873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 4.9615086907
MESH:D006965 Hyperplasia Diethylstilbestrol 3.5614722030 12960047
MESH:D006973 Hypertension Dexamethasone 8.7417042910
MESH:D006973 Hypertension Nifedipine 8.7420102058
MESH:D006973 Hypertension Phenylephrine 8.7412717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.7418670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 8.5015338365
MESH:D006975 Hypertension, Portal Hydrochloric Acid 8.5016984587
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.4116612254
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 3.7719262391
MESH:D006984 Hypertrophy Phenylephrine 3.7312791704 18502941
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.5017488730
MESH:D006996 Hypocalcemia zoledronic acid 5.2812669777
MESH:C537153 Hypomagnesemia primary Furosemide 4.7511041285
MESH:D007019 Hypoproteinemia Furosemide 4.9616096441
MESH:D007021 Hypospadias Diethylstilbestrol 3.7016002989
MESH:D007022 Hypotension Furosemide 7.0411041285
MESH:D007022 Hypotension Hydrochloric Acid 7.0411574821
MESH:D007024 Hypotension, Orthostatic Furosemide 4.5115811171
MESH:D007077 Ileal Diseases Indomethacin 4.1110574470 18306037
MESH:D007079 Ileitis Indomethacin 4.4516133968 10651667 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.4616133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 8.5815869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 8.5817600658
MESH:D007246 Infertility Diethylstilbestrol 3.5015036965
MESH:D007247 Infertility, Female Acrylamide 8.1611020651
MESH:D007247 Infertility, Female Dieldrin 8.1610630421
MESH:D007248 Infertility, Male Acrylamide 14.2112507653 15749267 11020651 15355880
MESH:D007248 Infertility, Male Diazinon 14.2112948887 16466525
MESH:D007248 Infertility, Male fulvestrant 14.2111514358
MESH:D007248 Infertility, Male Gossypol 14.2111202417 9639145
MESH:D007248 Infertility, Male sodium arsenite 14.2112646999 15346721
MESH:D007249 Inflammation bisindolylmaleimide I 32.468273558
MESH:D007249 Inflammation Dexamethasone 32.468960868 11099482
MESH:D007249 Inflammation Hydrochloric Acid 32.4611574821
MESH:D007249 Inflammation Indomethacin 32.4612568917 3291741 7812673
MESH:D007249 Inflammation Nickel 32.4616166738
MESH:D007249 Inflammation polyphenols 32.4616366677
MESH:D007249 Inflammation Progesterone 32.4615869954
MESH:D007249 Inflammation resveratrol 32.4616366677
MESH:D007249 Inflammation Tamoxifen 32.4619457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 32.4612878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 32.4615177302 7812673 7562506 8273558 11698051
MESH:D007249 Inflammation Thalidomide 32.4616134734
MESH:D007251 Influenza, Human resveratrol 8.0716624496
MESH:D007251 Influenza, Human Vitamin E 8.0716624496
MESH:D007333 Insulin Resistance Estradiol 2.3316393666 16627594
MESH:D007410 Intestinal Diseases Hydrochloric Acid 11.5611574821
MESH:D007410 Intestinal Diseases Indomethacin 11.5611713966 10210152 15831440 17994277 17329856 11686837 18236018 15610444 11855677
MESH:D007410 Intestinal Diseases Tretinoin 11.5617994277
MESH:D019586 Intracranial Hypertension Indomethacin 4.4615241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.2116580747
MESH:D007569 Jaw Abnormalities Tretinoin 7.2117551590 15992940
MESH:D007579 Jejunal Diseases Indomethacin 4.1116133968 10574470 18306037
MESH:D007642 Keratosis imiquimod 5.6716302556
MESH:D007674 Kidney Diseases Estradiol 16.1215618244
MESH:D007674 Kidney Diseases Furosemide 16.1211041285
MESH:D007674 Kidney Diseases Indomethacin 16.1217190690
MESH:D007674 Kidney Diseases Mercury 16.1217934191
MESH:D007674 Kidney Diseases sodium arsenite 16.1220008137
MESH:D007674 Kidney Diseases Vitamin E 16.1212488133
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.4616518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 15.4016705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 15.4014681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Estradiol 15.4015610895
MESH:D007680 Kidney Neoplasms Fluorouracil 15.4016985049
MESH:D007680 Kidney Neoplasms Tamoxifen 15.4018625569
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 5.4516498863
MESH:D007826 Laryngismus Hydrochloric Acid 5.4511510729
MESH:D007859 Learning Disorders Diethylstilbestrol 3.2017184923
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.1611703811 12228301 10320625
MESH:D007898 Leishmaniasis, Visceral Thalidomide 3.6316514283
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 10.5912970779
MESH:D007938 Leukemia Genistein 10.5918980019 17468513
MESH:D007938 Leukemia temozolomide 10.5917500047
MESH:D007938 Leukemia Tretinoin 10.5917143497
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Drugs, Chinese Herbal 3.4615802533
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 3.9518089816
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 14.6616972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 14.6616972261
MESH:D007948 Leukemia, Monocytic, Acute U 0126 14.6616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.2215631656 10785260 16572323
MESH:D007951 Leukemia, Myeloid Tretinoin 2.8919285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.7518360721
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 4.7518720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.7519850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 5.5916087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 5.5919642359 17506722 16788101 19075265 17712046 17361223 9834237 12679006 16891316 16331271 17294898 19029980 16823087 17368321 17649720 19225113 19035177 15748426 17301526 16766008 17107899 16140955 16935935 17339181 17217047
MESH:D007964 Leukocytosis Indomethacin 4.4616537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.8017980183
MESH:D017880 Limb Deformities, Congenital Thalidomide 6.2310473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.239224671
MESH:D008064 Lipidoses Clozapine 5.7717567588
MESH:D008064 Lipidoses Tamoxifen 5.7717567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.8011479899
MESH:D008103 Liver Cirrhosis therapeutic 17093919
MESH:D008103 Liver Cirrhosis arsenite 14.6118296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.6111903743 16943688 17334410 11408273 16239168 16221502 17174718 21278145 17157831
MESH:D008103 Liver Cirrhosis Drugs, Chinese Herbal 14.6117163593
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 14.6116984587
MESH:D008103 Liver Cirrhosis Thalidomide 14.6116943688 17174718
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 16116963
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 22.9714748882 16011737 16015684 15362042 17805973 15650968 12666154 17976157 17823541 15893842 16116963 16033810 15370692 18205269 17761835 13678700 18277467 17900296 18317297 16097048 14512876 12586293 12389079 11481614 14716496 20821823 12898905 15123356 16136751 17721639 15338365 14724832 15730626 10355542 18481824 15996030 18210741 18429990 12632514 15052691 17708605 18279442 12649538 16027843 15925388 17565644 18054572 15959796 17922224 14716833 15931870 18263696 18395914 12609069 15673190 18395095 18006644 18420326 17944888 18339082 16638106 12741479 18472332 18376398 18166357 12958196 15057751 18187930 15818738 17714472 17698563 17631135 18472094 18418968 17481882 17766677 14620537 12632512 12546737 16192424 17557913 17525996 12445418 18251166 18705752 17640975 16248980 15876570 17869086 18156304 18412020 12445421 12667390
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 22.9716718785
MESH:D008106 Liver Cirrhosis, Experimental Drugs, Chinese Herbal 22.9718371158 15763062 18606216 15849816 15383259 15818738 18567088 17881167 12632512 17348192 16610055 15864749 17629604 18237412 15754396 15339415 15744066 15641146 17036385 17666798
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 22.9717481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 22.9714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 22.9717823541
MESH:D008106 Liver Cirrhosis, Experimental Heparin 22.9716904936
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 22.9718194892
MESH:D008106 Liver Cirrhosis, Experimental silybin 22.9716169303
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 22.9718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 22.9712878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 22.9715465738
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 22.9718397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 22.9716169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.6416964402 15720792 15830285 17285989 16246199
MESH:D008107 Liver Diseases Chlorpyrifos 6.6415991261
MESH:D008107 Liver Diseases Drugs, Chinese Herbal 6.6417207593
MESH:D008107 Liver Diseases polyphenols 6.6416698588
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 2.8916899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 31.107678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 31.1020195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 31.1019294768
MESH:D008113 Liver Neoplasms Dieldrin 31.108742319 9539021
MESH:D008113 Liver Neoplasms Diethylstilbestrol 31.1015890375 16712894
MESH:D008113 Liver Neoplasms Drugs, Chinese Herbal 31.1018339527
MESH:D008113 Liver Neoplasms Fluorouracil 31.1017045692 18383874 15113037 16603448
MESH:D008113 Liver Neoplasms resveratrol 31.1019812893 20405173 19073162 19321006
MESH:D008113 Liver Neoplasms sodium arsenite 31.1016712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 31.1016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 31.1016984957
MESH:D008113 Liver Neoplasms Urethane 31.1017093202 17559639 16391232
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 8.982876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 8.9818544905
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 8.9812014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 8.9812151625
MESH:D008133 Long QT Syndrome Dobutamine 4.0219353679
MESH:D008171 Lung Diseases Acetylcysteine 29.0412815614
MESH:D008171 Lung Diseases Ascorbic Acid 29.0416863852
MESH:D008171 Lung Diseases Dobutamine 29.0416638327
MESH:D008171 Lung Diseases Hydrochloric Acid 29.0416784557
MESH:D008171 Lung Diseases nitrofen 29.049859898 17245593 16863852 9614859
MESH:D008171 Lung Diseases Ozone 29.048266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 29.0419095001
MESH:D008171 Lung Diseases Vitamin E 29.0416863852
MESH:D055370 Lung Injury Asbestos, Crocidolite 10.3417365036
MESH:D055370 Lung Injury Hydrochloric Acid 10.3421114838 21311175 19644408 19262391 17627322 15044056 20597076 18573544 15607125 16129981 11395602 18339021 15090967 18497604
MESH:D055370 Lung Injury Ozone 10.3420417186
MESH:D008175 Lung Neoplasms arsenite 27.6216809336
MESH:D008175 Lung Neoplasms Ascorbic Acid 27.6216401635
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 27.626695378 20464547 18520028 18569708 20135361 20064080 17053015 18816296 20869020
MESH:D008175 Lung Neoplasms Dexamethasone 27.6215824018 11195469
MESH:D008175 Lung Neoplasms Drugs, Chinese Herbal 27.6218339527
MESH:D008175 Lung Neoplasms Fluorouracil 27.6215246190
MESH:D008175 Lung Neoplasms Indomethacin 27.6216537180 11497255 11053908
MESH:D008175 Lung Neoplasms Ozone 27.627614698 8597069
MESH:D008175 Lung Neoplasms silybin 27.6216788158
MESH:D008175 Lung Neoplasms sodium arsenite 27.6216712894 17077188 17306315 15276417 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 27.6218625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 27.6219555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 27.6211807781
MESH:D008175 Lung Neoplasms Urethane 27.6216391232 16007126 11544531 11246140 12957351 16788158 11497255 17195641 16204055 14587096 12765245 11552296 11992545 11307925 6695378 16337739 11807781 12117781 10822126 15136453 11074608 17093202 17255336 10530776 11893704 7750092 10997738 10779650 12466968 11323394 11062179 16926031 15902970 15166089 16289808
MESH:D008175 Lung Neoplasms vanadium pentoxide 27.6212376484
MESH:D008175 Lung Neoplasms Vitamin E 27.6211062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 3.8915086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.2515166399
MESH:D008223 Lymphoma Diethylstilbestrol 5.6215700306
MESH:D008223 Lymphoma Etoposide 5.6212854902 12556972
MESH:D016393 Lymphoma, B-Cell resveratrol 3.4617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.1214749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.6016002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 7.0515688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.0519428831
MESH:D008325 Mammary Neoplasms, Experimental Drugs, Chinese Herbal 26.0014758024
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 26.0011807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 26.0014578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 26.0017203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 26.0011606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 26.0016827153 11731420 19196722 14580682 19196723
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 26.008985016
MESH:D008325 Mammary Neoplasms, Experimental Tocopherols 26.0017927505
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 26.0017312309
MESH:D020149 Manganese Poisoning Estradiol 9.6219453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.6219453300
MESH:D008527 Medulloblastoma Tretinoin 2.3317453147
MESH:D008545 Melanoma epigallocatechin gallate 11.2711746506 17992120
MESH:D008545 Melanoma resveratrol 11.2717992120
MESH:D008545 Melanoma sodium arsenite 11.2719082730 16487513
MESH:D008545 Melanoma Tamoxifen 11.2719393235 12393984
MESH:D008545 Melanoma temozolomide 11.2712374674 15577323 17576461 16248763 18281670 16432458 16225601 10623706 16260693 12829675 17623835 16260697
MESH:D008545 Melanoma Thalidomide 11.2716098027 12829675 17089043
MESH:D008545 Melanoma Tretinoin 11.2716752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.2915990972
MESH:D008591 Meningomyelocele Tretinoin 3.5516940565
MESH:D001523 Mental Disorders Clozapine 3.1016856516
MESH:D008654 Mesothelioma marker/mechanism 15878867
MESH:D008654 Mesothelioma Asbestos, Crocidolite 7.7816966607 16166281 18303189
MESH:D008654 Mesothelioma Tocopherols 7.7815878867
MESH:D008654 Mesothelioma zoledronic acid 7.7816675582
MESH:D008659 Metabolic Diseases resveratrol 3.5617112576
MESH:D024821 Metabolic Syndrome X Clozapine 3.6519142101
MESH:D008679 Metaplasia Ozone 4.1910496685
MESH:D008881 Migraine Disorders Indomethacin 3.0011903285
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 10.2116381670
MESH:D009062 Mouth Neoplasms Fluorouracil 10.2116757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 10.2112636206
MESH:D052016 Mucositis irinotecan 4.1117159606
MESH:D009101 Multiple Myeloma Dexamethasone 11.7215867202 16118317 15744524
MESH:D009101 Multiple Myeloma resveratrol 11.7217164350 16490592 16267019 14749477 17049120 17935668
MESH:D009101 Multiple Myeloma Thalidomide 11.7215867202 15939924 15744524 17168659 19112201 15741222 19112817 19372569 16445831 15920492
MESH:D009101 Multiple Myeloma zoledronic acid 11.7218089719 16996129 19621390
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 9.6517962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 9.6517962980
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 9.029809623
MESH:D009190 Myelodysplastic Syndromes Thalidomide 9.0218720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 9.0217596541
MESH:D009203 Myocardial Infarction Genistein 6.9017141266
MESH:D009203 Myocardial Infarction Hydrochloric Acid 6.9018534312
MESH:D009203 Myocardial Infarction resveratrol 6.9016525036 17015251 17188708 17125593 16317513 16456233
MESH:D017202 Myocardial Ischemia therapeutic 12173832 14583313
MESH:D017202 Myocardial Ischemia Dobutamine 11.1312447174
MESH:D017202 Myocardial Ischemia resveratrol 11.1317125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 11.1312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.0916810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 6.0917141266
MESH:D009205 Myocarditis resveratrol 3.8617322642
MESH:D009336 Necrosis 2,6-dinitrotoluene 2.977678174 18551238
MESH:D009362 Neoplasm Metastasis Acetylcysteine 12.9514720322
MESH:D009362 Neoplasm Metastasis Indomethacin 12.9511239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis irinotecan 12.9518259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.9519393235
MESH:D009362 Neoplasm Metastasis zoledronic acid 12.9519139120 15867366 17312309
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1319410462
MESH:D009369 Neoplasms 4-phenylbutyric acid 25.5019116145
MESH:D009369 Neoplasms alliin 25.5016351512
MESH:D009369 Neoplasms Benzo(a)pyrene 25.5011141357
MESH:D009369 Neoplasms Dieldrin 25.508820588
MESH:D009369 Neoplasms Diethylstilbestrol 25.5015313581
MESH:D009369 Neoplasms Fluorouracil 25.5016928823 18600527 18239605
MESH:D009369 Neoplasms Nicotine 25.5016365874
MESH:D009369 Neoplasms sodium arsenite 25.5011559025
MESH:D009369 Neoplasms Tretinoin 25.5016594593 16946489
MESH:D009369 Neoplasms Urethane 25.5015625555
MESH:D009374 Neoplasms, Experimental Indomethacin 14.7210663608 15625704
MESH:D009374 Neoplasms, Experimental resveratrol 14.728985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 14.7220056578
MESH:D009374 Neoplasms, Experimental Urethane 14.7215582191
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.0919189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic alliin 22.4216351512
MESH:D009389 Neovascularization, Pathologic arsenite 22.4215738583
MESH:D009389 Neovascularization, Pathologic Estradiol 22.4217289903
MESH:D009389 Neovascularization, Pathologic Nicotine 22.4216365874
MESH:D009389 Neovascularization, Pathologic parthenolide 22.4216921510
MESH:D009397 Nephrocalcinosis Furosemide 4.9615086907
MESH:D009404 Nephrotic Syndrome marker/mechanism 21441931
MESH:D009410 Nerve Degeneration Acrylamide 3.9712387367 11264303 12387366
MESH:D009422 Nervous System Diseases Acrylamide 4.2112507653 12164553
MESH:D009421 Nervous System Malformations Diethylstilbestrol 27.3411399458
MESH:D009421 Nervous System Malformations Estradiol 27.3416427766 11399458
MESH:D009421 Nervous System Malformations Genistein 27.3416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 27.3414600291
MESH:D009421 Nervous System Malformations Thalidomide 27.3416859833
MESH:D009421 Nervous System Malformations Tretinoin 27.349125849
MESH:D009436 Neural Tube Defects Acetylcysteine 8.4919446573
MESH:D009436 Neural Tube Defects sodium arsenite 8.4912854658
MESH:D009436 Neural Tube Defects Tretinoin 8.499142499
MESH:D009447 Neuroblastoma irinotecan 8.548761367
MESH:D009447 Neuroblastoma temozolomide 8.5415176712
MESH:D009447 Neuroblastoma Topotecan 8.5415176712
MESH:D019636 Neurodegenerative Diseases Amphetamine 9.9915183010
MESH:D019636 Neurodegenerative Diseases Indomethacin 9.9912349958
MESH:D019636 Neurodegenerative Diseases resveratrol 9.9917652729
MESH:D017599 Neuroectodermal Tumors irinotecan 3.848761367
MESH:D020078 Neurogenic Inflammation resveratrol 3.5617929310
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 6.0815081274
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 6.0816436463
MESH:D053206 Nocturnal Enuresis Furosemide 4.9617945291
MESH:D009765 Obesity Ascorbic Acid 4.0917217161
MESH:D009765 Obesity Clozapine 4.0919142110 18515891
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.266374098
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 6.7316049721
MESH:D009784 Occupational Diseases Hydrochloric Acid 6.7312378975
MESH:D009914 Oral Submucous Fibrosis marker/mechanism 16311067
MESH:D010003 Osteoarthritis Indomethacin 3.057009135
MESH:D010014 Osteolysis zoledronic acid 4.4715867366
MESH:D010024 Osteoporosis Genistein 5.4819401787
MESH:D010024 Osteoporosis zoledronic acid 5.4817882678
MESH:D015663 Osteoporosis, Postmenopausal Drugs, Chinese Herbal 12.1816548355
MESH:D015663 Osteoporosis, Postmenopausal Genistein 12.1816169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 12.1817513867
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 23.4516211241
MESH:D010051 Ovarian Neoplasms Estradiol 23.4519401270
MESH:D010051 Ovarian Neoplasms Genistein 23.4519005980
MESH:D010051 Ovarian Neoplasms Progesterone 23.4516525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 23.4517306315 15276417
MESH:D010051 Ovarian Neoplasms Thalidomide 23.4516288038
MESH:D010051 Ovarian Neoplasms Tretinoin 23.4516936753
MESH:D010051 Ovarian Neoplasms U 0126 23.4516211241
MESH:D010051 Ovarian Neoplasms Urethane 23.4516391232
MESH:D010146 Pain Indomethacin 7.183291741 17627676 13679232 17440234
MESH:D010146 Pain Tretinoin 7.1816870215
MESH:D010146 Pain zoledronic acid 7.1816475674
MESH:D010149 Pain, Postoperative Indomethacin 3.7712538197 18702446
MESH:D010190 Pancreatic Neoplasms Etoposide 8.7819003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.7816929163 16500647 15113037 19003803
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 8.7815976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.7815976015
MESH:D010195 Pancreatitis Indomethacin 3.1115028970 17883296
MESH:D010212 Papilloma Hydrogen Peroxide 6.7312065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 6.738330346 18404319 12065085 18922899
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.8016537180
MESH:D010291 Paresis Thalidomide 5.399200351
MESH:D010300 Parkinson Disease Dieldrin 3.1211181820 11445065 17291500 16809432 16112328
MESH:D020734 Parkinsonian Disorders Indomethacin 3.3312349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.8011903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3312520081
MESH:D010437 Peptic Ulcer Indomethacin 4.2511148446
MESH:D010518 Periodontitis Indomethacin 4.0017225004
MESH:D010523 Peripheral Nervous System Diseases Acrylamide 4.2611510240
MESH:D010538 Peritonitis Ozone 3.2616369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.2614722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 9.2215687265 16977796
MESH:D010911 Pituitary Neoplasms Urethane 9.2216391232
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.0110923243
MESH:D011014 Pneumonia Ozone 3.5018381685 18929643 18007984
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 4.4818497604 18573544 15607125 15970105
MESH:D011041 Poisoning Diazinon 3.5417603234
MESH:D011141 Polyuria Furosemide 4.7517945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.7018163543
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 6.0021297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 6.0017031469
MESH:D011225 Pre-Eclampsia Iloprost 5.0010329876
MESH:D047928 Premature Birth Indomethacin 4.2517000239
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 11.1817184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 11.1816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 11.1811222880 11118676 11896295 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0620887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 6.1817292933
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 6.1817136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 6.1816740699
MESH:D011471 Prostatic Neoplasms Etoposide 6.1817172428
MESH:D011471 Prostatic Neoplasms Fluorouracil 6.1818626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 6.1815256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms methylselenic acid 6.1816205645
MESH:D011471 Prostatic Neoplasms parthenolide 6.1816921510
MESH:D011471 Prostatic Neoplasms resveratrol 6.1817718901 17636462 16731767 17675339 15767336 17804756
MESH:D011471 Prostatic Neoplasms sodium arsenite 6.1816039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 6.1815067354
MESH:D011471 Prostatic Neoplasms Thalidomide 6.1816729912
MESH:D011471 Prostatic Neoplasms Tocopherols 6.1812504091
MESH:D011471 Prostatic Neoplasms Vitamin E 6.1815084515
MESH:D011471 Prostatic Neoplasms zoledronic acid 6.1812438248 19103299
MESH:D011507 Proteinuria Indomethacin 6.5711849393
MESH:D011507 Proteinuria Tretinoin 6.5716636307
MESH:D011536 Prurigo Thalidomide 5.3912755975
MESH:D011618 Psychotic Disorders Clozapine 3.4915331141
MESH:D011625 Pterygium Tretinoin 3.8916723453
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.1020597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.3115090967
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.4214606601
MESH:D011658 Pulmonary Fibrosis marker/mechanism 8952537
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 4.6917365031 17322281 17975199 15814490
MESH:D011658 Pulmonary Fibrosis Drugs, Chinese Herbal 4.6916987627
MESH:D011928 Raynaud Disease Iloprost 5.7116363279
MESH:D012003 Rectal Fistula Drugs, Chinese Herbal 5.0515043669
MESH:D012004 Rectal Neoplasms Fluorouracil 3.2315538739 16160472 18722050 18286688
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.6716325855
MESH:D015427 Reperfusion Injury marker/mechanism 16526316
MESH:D015427 Reperfusion Injury Furosemide 5.3316526316
MESH:D015427 Reperfusion Injury resveratrol 5.3316314181 15827377 17520802 17058453 16317513
MESH:D012120 Respiration Disorders Chlorine 4.3018579056
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 14.9212210543
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 14.9218379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 14.9215912074 16096441 12394941
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 14.9217627322 18549715 16784557 16129981 18339021
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 5.4511510729
MESH:D012135 Respiratory Sounds Chlorpyrifos 3.7716611668 17119214 11874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9818990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 8.1217119214 16611668
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 8.1220516732
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 2.9716849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.2616283617 16116481
MESH:D012221 Rhinitis, Allergic, Perennial Drugs, Chinese Herbal 4.3715015336
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4418045962
MESH:D012512 Sarcoma, Ewing's Etoposide 7.9714601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 7.9716121404
MESH:D012514 Sarcoma, Kaposi imiquimod 5.5316302556
MESH:D012559 Schizophrenia Clozapine 2.5820452607 20168265 11763009 16141801 20521326 17667964 20580759 18806925 18855531 19369910 17726453 20521320 20107430 17123785 11151749
MESH:D019873 Schnitzler Syndrome Thalidomide 5.0416096327
MESH:D012640 Seizures 2,6-dinitrotoluene 6.3918551238
MESH:D012640 Seizures Kainic Acid 6.3914637104 18657176 1641125 17827730 15686955 10686065 16336964 19186208 19414003
MESH:D012640 Seizures Nicotine 6.3917873105
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.176418539
MESH:D012852 Sinusitis Phenylephrine 3.817327846
MESH:D012851 Sinus Thrombosis, Intracranial Heparin 5.1812269725
MESH:D012871 Skin Diseases Ascorbic Acid 6.1918709164
MESH:D012871 Skin Diseases monomethylarsonic acid 6.1921378128
MESH:D012871 Skin Diseases Vitamin E 6.1918709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 22.8119755658 10029692
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 22.8112065085
MESH:D012878 Skin Neoplasms resveratrol 22.8115837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 22.8118572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 22.8116192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 22.818330346 12065085 18404319 11807781 8985016
MESH:D012878 Skin Neoplasms Tretinoin 22.8116467112
MESH:D012878 Skin Neoplasms Urethane 22.8111807781
MESH:D012893 Sleep Disorders Kainic Acid 4.8119414003
MESH:D013088 Spermatocele Diethylstilbestrol 8.8216709447 16002989
MESH:D013088 Spermatocele Tamoxifen 8.8216709447
MESH:D013119 Spinal Cord Injuries Progesterone 7.9116503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 7.9119457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0612854658
MESH:D019956 Stereotypic Movement Disorder Amphetamine 5.511977408
MESH:D013272 Stomach Diseases Dexamethasone 7.4115472012
MESH:D013272 Stomach Diseases Indomethacin 7.4116113693 15038085 10192188 10215738 18545984 10486359 16280098 15472012 16184426 17207306 17638125 17160473 18209964
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 9.5920155912 2093021
MESH:D013274 Stomach Neoplasms Drugs, Chinese Herbal 9.5918339527
MESH:D013274 Stomach Neoplasms Fluorouracil 9.5917498489 17522103 18567086 18396642 16951190 16424979 19084572 17172411 19015929 15786421
MESH:D013274 Stomach Neoplasms Furosemide 9.5917052386
MESH:D013274 Stomach Neoplasms Indomethacin 9.5915609394
MESH:D013274 Stomach Neoplasms irinotecan 9.5915723263
MESH:D013274 Stomach Neoplasms S 1 (combination) 9.5918553229 16557585 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 9.5917261132
MESH:D013276 Stomach Ulcer Acetylcysteine 25.6917918041
MESH:D013276 Stomach Ulcer Aluminum Silicates 25.6916335828
MESH:D013276 Stomach Ulcer Ascorbic Acid 25.6918726076
MESH:D013276 Stomach Ulcer Dexamethasone 25.6915138204
MESH:D013276 Stomach Ulcer Hydrochloric Acid 25.6916755016 15309881 17189318
MESH:D013276 Stomach Ulcer Indomethacin 25.6912498302 18726076 18209962 17895592 18299717 17918041 11729361 18181030 16252198 12787963 11595415 17654042 18087811 16397915 17657623 11906479 11595431 16150113 12500499 15255614 16169175 17977527 16934674 1323529 18193104 17627676 12467913 10878458 11145282 16631530 14567935 18237397 10423059 17135157 16755016 18431645 11523592 15104355 10750652 15138204 12077510 18543354
MESH:D013276 Stomach Ulcer Nifedipine 25.6914653237
MESH:D013276 Stomach Ulcer Thalidomide 25.6915138204
MESH:D020521 Stroke Ascorbic Acid 6.4116517955 16403987
MESH:D020521 Stroke Vitamin E 6.4116517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.6816321402
MESH:D013345 Subarachnoid Hemorrhage Drugs, Chinese Herbal 4.8517634840
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.3417997062
MESH:D013733 Testicular Diseases Acrylamide 4.3415864552
MESH:D013921 Thrombocytopenia Heparin 4.6616893407 16651880
MESH:D013927 Thrombosis Heparin 4.5316893407
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.9912697716
MESH:D013964 Thyroid Neoplasms Indomethacin 5.0214736730 18791128 11352223
MESH:D013964 Thyroid Neoplasms Tretinoin 5.0216026305 17045167
MESH:D013978 Tibial Fractures Estradiol 3.7719048282
OMIM:188890 TOBACCO ADDICTION, SUSCEPTIBILITY TO Nicotine 4.0216785264 11259349 16720336
MESH:D014029 Tobacco Use Disorder Nicotine 4.5717979512 18305452 15735609 18041664
MESH:D014062 Tongue Neoplasms Fluorouracil 11.9716280240
MESH:D014062 Tongue Neoplasms resveratrol 11.9716227395
MESH:D014062 Tongue Neoplasms Tretinoin 11.9716051514
MESH:D016171 Torsades de Pointes Dobutamine 4.4619353679
MESH:D014376 Tuberculosis Tretinoin 2.6016040207
MESH:D014456 Ulcer Indomethacin 4.0017380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 13.8416049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 13.8417053015
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 13.8415537745
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 13.8417306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 13.8417306315 11723127 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 13.8416712894 17572228 8653321
MESH:D014570 Urologic Diseases Diazinon 4.3716487989
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.4210091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 21.2616175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 21.2616803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 21.2617473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 21.2611813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 21.2616129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.2614652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 6.9515809267 16690809
MESH:D014594 Uterine Neoplasms resveratrol 6.9517044934
MESH:D014604 Uveal Neoplasms Tretinoin 3.7016752155
MESH:D014605 Uveitis Dexamethasone 3.911336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 8.6816002989 16513791
MESH:D014625 Vaginal Neoplasms temozolomide 8.6815577323
MESH:D014652 Vascular Diseases sodium arsenite 9.1517056641
MESH:D014652 Vascular Diseases Thalidomide 9.1515741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6812125929
MESH:D019043 Vascular Neoplasms Urethane 5.0010620525
MESH:D014657 Vasculitis Heparin 5.1820337814
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.4317488730
MESH:D014820 Vitiligo Tretinoin 3.2016761959
MESH:D014839 Vomiting Indomethacin 3.8411897121
MESH:D014860 Warts imiquimod 5.8816368197
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3315886252
MESH:D015430 Weight Gain Clozapine 3.6920107430 16141801 20564506 16402076 20521320 17502770
MESH:D015431 Weight Loss Clozapine 4.1817933447
MESH:D009396 Wilms Tumor Tretinoin 3.1816287080
MESH:D014947 Wounds and Injuries Drugs, Chinese Herbal 3.7916313111
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
KEGG:05218 Melanoma
KEGG:05200 Pathways in cancer
KEGG:04810 Regulation of actin cytoskeleton
REACT:9470 Signaling by FGFR
REACT:498 Signaling by Insulin receptor
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28115
    • No data
    Releated disease ID Related disease Name
    PA445062Neoplasms
    Releated drug ID Related drug Name
    PA448976choline
    PA448478l-arginine
    PA450635nitric oxide
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00364 agonist Sucralfate Anti-Ulcer Agents
    DB00686 antagonist Pentosan Polysulfate Anticoagulants;Enzyme Inhibitors
    DB00877 other/unknown Sirolimus Anti-Bacterial Agents;Antifungals;Immunosuppressive Agents;Antifungal Agents;Antibiotics, Antineoplastic;Macrolides
    DB03131 - Beta-Mercaptoethanol
    DB03935 - 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
    DB03959 - N,O6-Disulfo-Glucosamine
    DB03981 - 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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