AutismKB 2.0

Annotation Detail for FGFR2


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Basic Information Top
Gene Symbol:FGFR2 ( BEK,BFR-1,CD332,CEK3,CFD1,ECT1,FLJ98662,JWS,K-SAM,KGFR,TK14,TK25 )
Gene Full Name: fibroblast growth factor receptor 2
Band: 10q26.13
Quick LinksEntrez ID:2263; OMIM: 176943; Uniprot ID:FGFR2_HUMAN; ENSEMBL ID: ENSG00000066468; HGNC ID: 3689
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04144Endocytosis
hsa04810Regulation of actin cytoskeleton
hsa05215Prostate cancer
hsa05200Pathways in cancer
Pathway IDPathway Name
Signaling by Insulin receptor
Signaling by FGFR
Pathway IDPathway Name
200189FGF signaling pathway
Pathway IDPathway Name
P00021FGF signaling pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers
Cancers of the digestive system
H00018Gastric cancer
Desease IDDesease Name
1901Endometriosis
1934Cancer
1942Emphysema
2249Craniosynostosis
Desease Name
CANCER
breast cancer
Pfeiffer syndrome
Chiari type I malformation and syringomyelia
DEVELOPMENTAL
craniosynostosis
hair thickness
Desease Name
Breast cancer
Desease Name
Beare-Stevenson cutis gyrata syndrome
Craniosynostosis, nonspecific
Antley-Bixler syndrome
Pfeiffer syndrome
Saethre-Chotzen syndrome
Jackson-Weiss syndrome
Apert syndrome
Craniofacial-skeletal-dermatologic dysplasia
Crouzon syndrome
Gastric cancer, somatic
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of FGFR2 mRNAdecreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of FGFR2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of FGFR2 mRNAincreases expression 20406850
D000096 Acetone Acetone results in increased expression of FGFR2 mRNAincreases expression 12720008
C005277 alpha-naphthyl thiourea alpha-naphthyl thiourea results in increased expression of FGFR2 mRNAincreases expression 10755703
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FGFR2 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of FGFR2 mRNAdecreases expression 15761015
D001554 Benzene Benzene results in increased expression of FGFR2 mRNAincreases expression 15122651
15120971
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of FGFR2 mRNAincreases expression 19150397
C006780 bisphenol A bisphenol A affects the expression of FGFR2 mRNAaffects expression 20170705
C487049 BXL628 BXL628 inhibits the reaction [FGF7 protein results in increased phosphorylation of FGFR2 protein]decreases reaction|increases phosphorylation 16289173
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of FGFR2 mRNAdecreases expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of FGFR2 mRNAincreases expression 17692400
16644059
D004390 Chlorpyrifos Chlorpyrifos affects the expression of FGFR2 mRNAaffects expression 18502319
D003008 Cloprostenol Cloprostenol results in increased expression of FGFR2 mRNAincreases expression 14991729
C007164 cumene hydroperoxide cumene hydroperoxide results in increased phosphorylation of and results in increased activity of FGFR2 proteinincreases activity|increases phosphorylation 12717419
D003474 Curcumin Curcumin results in decreased expression of FGFR2 mRNAdecreases expression 15713895
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D002945 Cisplatin FGFR2 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D002117 Calcitriol Calcitriol results in increased expression of FGFR2 proteinincreases expression 12761878
C010452 estradiol-17 beta-benzoate estradiol-17 beta-benzoate affects the expression of FGFR2 mRNAaffects expression 15059950
C074283 estradiol 3-benzoate estradiol 3-benzoate results in decreased expression of FGFR2 mRNA alternative formdecreases expression 15976484
C074283 estradiol 3-benzoate [Progesterone co-treated with estradiol 3-benzoate] results in decreased expression of FGFR2 mRNA alternative formaffects cotreatment|decreases expression 15976484
D004958 Estradiol ESR2 protein affects the reaction [Estradiol results in decreased expression of FGFR2 mRNA]affects reaction|decreases expression 14699072
D004958 Estradiol Estradiol affects the expression of FGFR2 mRNAaffects expression 14699072
D004958 Estradiol Estradiol results in increased expression of FGFR2 mRNA alternative formincreases expression 14602803
D004958 Estradiol Estradiol results in increased expression of FGFR2 protein alternative formincreases expression 18575591
D004958 Estradiol Estradiol results in decreased expression of FGFR2 mRNA alternative formdecreases expression 15680359
D004958 Estradiol Estradiol results in decreased expression of FGFR2 protein alternative formdecreases expression 15680359
C024552 estrone benzoate estrone benzoate results in decreased expression of FGFR2 mRNA alternative formdecreases expression 15120423
D000431 Ethanol Ethanol results in increased expression of FGFR2 mRNAincreases expression 12720008
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of FGFR2 mRNAaffects expression 20170705
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of FGFR2 mRNAaffects expression 20170705
D005419 Flavonoids Flavonoids results in increased expression of FGFR2 mRNAincreases expression 18035473
D005472 Fluorouracil FGFR2 protein alternative form inhibits the reaction [FGF7 protein results in decreased susceptibility to Fluorouracil]decreases reaction|decreases response to substance 18575591
C006326 fluprostenol fluprostenol results in decreased expression of FGFR2 mRNAdecreases expression 15654655
D005576 Forskolin Forskolin results in increased expression of FGFR2 mRNAincreases expression 10320526
D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGFR2 protein]affects localization|decreases reaction 15654655
D006493 Heparin [Heparin analog binds to FGFR2 protein alternative form] which binds to and results in increased activity of FGF1 proteinaffects binding|increases activity 16219767
D006493 Heparin Heparin promotes the reaction [FGF10 protein binds to FGFR2 protein]affects binding|increases reaction 15632068
D006493 Heparin Heparin affects the activity of FGFR2 proteinaffects activity 1373495
D006493 Heparin Heparin promotes the reaction [FGFR2 protein binds to FGF2 protein]affects binding|increases reaction 1373495
D006493 Heparin [Heparin binds to FGFR2 protein alternative form] which binds to FGF1 proteinaffects binding 10860838
D006493 Heparin [Heparin binds to FGFR2 protein alternative form] which binds to FGF2 proteinaffects binding 10860838
D006493 Heparin [Heparin binds to FGFR2 protein alternative form] which binds to FGF7 proteinaffects binding 10860838
D006493 Heparin FGF1 protein binds to FGFR2 protein binds to Heparinaffects binding 16223363
15165853
D006497 Heparitin Sulfate Heparitin Sulfate analog results in decreased activity of FGFR2 protein mutant formdecreases activity 16373332
D006497 Heparitin Sulfate FGF7 protein binds to Heparitin Sulfate binds to FGFR2 protein alternative formaffects binding 16315317
D006497 Heparitin Sulfate Heparitin Sulfate analog promotes the reaction [FGF1 protein results in increased activity of FGFR2 protein alternative form]increases activity|increases reaction 11714710
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of FGFR2 mRNAincreases expression 15883737
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of FGFR2 mRNAdecreases expression 17997286
D006861 Hydrogen Peroxide Sodium Selenite promotes the reaction [Hydrogen Peroxide results in decreased expression of FGFR2 mRNA]decreases expression|increases reaction 17997286
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C533894 LG 100815 LG 100815 results in increased expression of FGFR2 mRNAincreases expression 16951191
D008044 Linuron Linuron results in decreased expression of FGFR2 mRNAdecreases expression 12730624
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of and affects the localization of FGFR2 proteinaffects localization|increases expression 15581186
D009151 Mustard Gas Mustard Gas affects the expression of FGFR2 mRNAaffects expression 15651846
D009151 Mustard Gas Mustard Gas results in decreased expression of FGFR2 mRNAdecreases expression 18988085
D037742 Nanotubes, Carbon Nanotubes, Carbon results in increased expression of FGFR2 mRNAincreases expression 15585362
C029938 nickel sulfate nickel sulfate results in increased expression of FGFR2 proteinincreases expression 12930308
D005996 Nitroglycerin Nitroglycerin results in increased expression of FGFR2 mRNAincreases expression 12102619
C100284 norgestomet norgestomet results in decreased expression of FGFR2 mRNA alternative formdecreases expression 10954858
C062198 octa-2,4,6-trienoic acid octa-2,4,6-trienoic acid results in increased expression of FGFR2 mRNAincreases expression 16951191
D009844 Oligosaccharides Oligosaccharides promotes the reaction [FGF1 protein results in increased activity of FGFR2 protein alternative form]increases activity|increases reaction 11714710
D009844 Oligosaccharides Oligosaccharides promotes the reaction [FGF7 protein binds to and results in increased activity of FGFR2 protein alternative form]affects binding|increases activity|increases reaction 11714710
C030110 oxaliplatin oxaliplatin results in increased expression of FGFR2 mRNAincreases expression 17762391
D010672 Phenytoin Phenytoin results in increased expression of FGFR2 mRNAincreases expression 11352631
D010672 Phenytoin Phenytoin results in increased expression of FGFR2 proteinincreases expression 11352631
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of FGFR2 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of FGFR2 mRNAincreases expression 18301758
D011374 Progesterone Progesterone affects the expression of FGFR2 mRNAaffects expression 17251523
D011374 Progesterone [Progesterone co-treated with estradiol 3-benzoate] results in decreased expression of FGFR2 mRNA alternative formaffects cotreatment|decreases expression 15976484
D011374 Progesterone Progesterone results in decreased expression of FGFR2 mRNA alternative formdecreases expression 15120423
D015237 Dinoprost 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGFR2 protein]affects localization|decreases reaction 15654655
D015237 Dinoprost Dinoprost affects the localization of [FGF2 protein binds to FGFR2 protein]affects binding|affects localization 16365892
D015237 Dinoprost Dinoprost affects the localization of FGFR2 proteinaffects localization 15654655
D015237 Dinoprost Dinoprost promotes the reaction [FGF2 protein binds to FGFR2 protein]affects binding|increases reaction 16365892
D015237 Dinoprost Dinoprost results in decreased expression of FGFR2 mRNAdecreases expression 15654655
D015237 Dinoprost Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGFR2 protein]affects localization|decreases reaction 15654655
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNAaffects cotreatment|decreases expression 19059307
D017382 Reactive Oxygen Species Reactive Oxygen Species results in increased phosphorylation of and results in increased activity of FGFR2 proteinincreases activity|increases phosphorylation 12717419
C052785 rebamipide rebamipide results in increased expression of FGFR2 mRNAincreases expression 15104358
C052785 rebamipide rebamipide results in increased expression of FGFR2 mRNA alternative formincreases expression 15104358
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D018038 Sodium Selenite Sodium Selenite promotes the reaction [Hydrogen Peroxide results in decreased expression of FGFR2 mRNA]decreases expression|increases reaction 17997286
C053081 sucrose octasulfate sucrose octasulfate binds to FGFR2 proteinaffects binding 15047176
D013498 Suramin Suramin inhibits the reaction [FGF7 protein binds to FGFR2 protein]affects binding|decreases reaction 15733146
D014284 Triiodothyronine Triiodothyronine results in increased expression of FGFR2 mRNAincreases expression 16150908
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNAaffects cotreatment|decreases expression 19059307
D013739 Testosterone Testosterone results in decreased expression of FGFR2 mRNAdecreases expression 7536664
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] results in decreased expression of FGFR2 mRNAaffects cotreatment|decreases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FGFR2 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of FGFR2 mRNAdecreases expression 17586704
19933214
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of FGFR2 mRNAincreases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of FGFR2 mRNAincreases expression 18796159
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGFR2 protein]affects localization|decreases reaction 15654655
C402769 tipifarnib tipifarnib results in increased expression of FGFR2 mRNAincreases expression 16403772
D014212 Tretinoin Tretinoin results in decreased expression of FGFR2 mRNAdecreases expression 7680553
D014212 Tretinoin Tretinoin results in decreased expression of FGFR2 proteindecreases expression 15389522
C034028 vanadyl sulfate vanadyl sulfate results in increased expression of FGFR2 mRNAincreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.8814745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 10.6418926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 10.6410563481 9118846 3425630 6195326 8986270 9677735
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.6415322242 14514962 11752688
MESH:D000015 Abnormalities, Multiple marker/mechanism 10631169
MESH:D000138 Acidosis Ammonium Chloride 14.1118287403
MESH:D000138 Acidosis Ethanol 14.1111192467
MESH:D000138 Acidosis Hydrochloric Acid 14.1116144966 19262391 12771618 20872349 15920416 11574821
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.1317183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.1420597076
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.2717505938
MESH:D000168 Acrocephalosyndactylia marker/mechanism 9002682 19186770 17694057 9502772
MESH:D058186 Acute Kidney Injury Cisplatin 3.3717670903 12690470 15814532
MESH:D055371 Acute Lung Injury Hydrochloric Acid 11.9316759491 11850527 19060228 19094174 19760209 15970105 11953099
MESH:D055371 Acute Lung Injury nickel sulfate 11.9312718980 19131640 16100012 11954676
MESH:D055371 Acute Lung Injury pirinixic acid 11.9318653653
MESH:D000230 Adenocarcinoma arsenic trioxide 14.2211798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 14.2217638652 11798837
MESH:D000230 Adenocarcinoma Estradiol 14.2211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 14.2214692618
MESH:D000230 Adenocarcinoma Fluorouracil 14.2217638652
MESH:D000230 Adenocarcinoma Methylnitrosourea 14.2215113128 15688392
MESH:D018248 Adenoma, Liver Cell pirinixic acid 7.7316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 7.7316835633
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 3.7011874814 16611668 17119214
MESH:D000419 Albuminuria Raloxifene 3.9717451421 17308373
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.6515451040 15451039
MESH:D019973 Alcohol-Related Disorders Curcumin 4.4117887948
MESH:D000505 Alopecia Tretinoin 3.0815955085
MESH:D000544 Alzheimer Disease Curcumin 5.5815590663
MESH:D000544 Alzheimer Disease Raloxifene 5.5815800139
MESH:D000544 Alzheimer Disease rosiglitazone 5.5819621015
MESH:D000740 Anemia Fluorouracil 6.7717963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.7711748828
MESH:D000741 Anemia, Aplastic Benzene 3.8511369114 17661222 14761424
MESH:D000844 Ankylosis marker/mechanism 9605588
MESH:D000853 Anophthalmos Ethanol 4.1815513904
MESH:D000860 Anoxia Hydrochloric Acid 4.6515090967
MESH:D000987 Antisocial Personality Disorder Testosterone 5.187506515
MESH:C537780 Antley-Bixler syndrome marker/mechanism
MESH:D054882 Antley-Bixler Syndrome Phenotype marker/mechanism 9605588
MESH:D001008 Anxiety Disorders Ethanol 3.4711141031
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.8311256880
MESH:D001169 Arthritis, Experimental Dexamethasone 9.7317659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 9.7315885639
MESH:D001169 Arthritis, Experimental Tretinoin 9.7316412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.0416807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.0416292516
MESH:D001249 Asthma Mustard Gas 4.1410378619
MESH:D001249 Asthma Tretinoin 4.1416456186
MESH:D050197 Atherosclerosis Curcumin 5.7418704882
MESH:D050197 Atherosclerosis Phenytoin 5.7415136057
MESH:D001327 Autoimmune Diseases Curcumin 3.8519761891
MESH:D001471 Barrett Esophagus Tretinoin 3.7816935849
MESH:D001768 Blister Mustard Gas 4.5019167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 22.5916206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 22.5915920416
MESH:D001778 Blood Coagulation Disorders pirinixic acid 22.5919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 22.5912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 22.5916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3115746008
MESH:D001855 Bone Marrow Diseases Benzene 4.5616183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.2214601052
MESH:D001862 Bone Resorption bisphenol A 3.2711985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.6717868700
MESH:D001930 Brain Injuries Progesterone 8.8415380490 15845082 15665606
MESH:D001930 Brain Injuries Raloxifene 8.8416580743
MESH:D002545 Brain Ischemia Curcumin 3.6816770732
MESH:D001932 Brain Neoplasms Curcumin 3.3717596214
MESH:D001943 Breast Neoplasms marker/mechanism 17529967 18438407 17529973
MESH:D001943 Breast Neoplasms Benzene 11.0117162533 11921183
MESH:D001943 Breast Neoplasms bisphenol A 11.0117123778
MESH:D001943 Breast Neoplasms Calcitriol 11.0111237771
MESH:D001943 Breast Neoplasms Cisplatin 11.0118382427 19526202
MESH:D001943 Breast Neoplasms Curcumin 11.0118462866 19250217 16243823 18593918
MESH:D001943 Breast Neoplasms Estradiol 11.0117289903 16675129 17261762 12948864 14630087 19861407 17018787 18497071
MESH:D001943 Breast Neoplasms Fluorouracil 11.0118608205 16110121 15136595 16557594 19217205 18357371 16595493
MESH:D001943 Breast Neoplasms Methylnitrosourea 11.0116253758 11306469 14633655
MESH:D001943 Breast Neoplasms Progesterone 11.0115562024 16175315 17614352
MESH:D001943 Breast Neoplasms Raloxifene 11.0116837676 15758505 17242785 15572757 17952589 16912660 17595753 17893378 17440819 15775269 17261762 17049068
MESH:D001943 Breast Neoplasms Tamoxifen 11.0119288272 20544844 18997820 18351453 21152245 21138602 19103187 11161223 18821012 15668708 17261762 19189212 19200415 19011961 19066611 17893378 20390343 20135344 19487384 19221464 17440819 19410462 17049068 19084267 18984771 19189210 20005174 15565566 20065188 19115204 18425577 18815881 16873071 19142967 20859285 18855134 16818667 16202921 19289846 19244106 17242785 16273361 19059307 18629630 19155303
MESH:D001943 Breast Neoplasms Testosterone 11.0117261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 11.0120435547
MESH:D001943 Breast Neoplasms Tretinoin 11.0116873071 16166294 16443354
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 4.0612378975
MESH:D001986 Bronchial Spasm Hydrochloric Acid 4.8015578804
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.5015286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.3117687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.9316813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7211589617
MESH:D002056 Burns Ethanol 4.0116374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.1418705752 15700767 10355542 15721981 3786805 15673190 16124888 16227642 16097048 16192424 16011737 16050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.0016051944
MESH:D002277 Carcinoma Curcumin 10.9018593918
MESH:D002277 Carcinoma Fluorouracil 10.9017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 10.9016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8619066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.4916168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 19.5516705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 19.5516705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 19.5515553829 15073043 16217749 11135700 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 19.5518788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 19.5517982673
MESH:D006528 Carcinoma, Hepatocellular Estradiol 19.5516924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 19.5515289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 19.5517088986 16799960 18930000 17045692 17971768 16332177
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 19.5516924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 19.551917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.3317123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 4.8412023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 4.8418414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2019014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.6718695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5412490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 14.8511237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 14.8517066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Curcumin 14.8518462866
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 14.8516280240 17066447 18986760 16757204
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 14.8518922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 14.8516051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 7.5917572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.5917572228
MESH:D006332 Cardiomegaly Ethanol 5.5019332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.5018850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 5.9916936243
MESH:D002318 Cardiovascular Diseases Raloxifene 5.9915775269
MESH:D002386 Cataract Methylnitrosourea 6.3312484553
MESH:D002386 Cataract Tretinoin 6.3317460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 16.116135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 16.1120889678
MESH:D002471 Cell Transformation, Neoplastic Dinoprost 16.1116192471
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.1118566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 16.117505956 2727394
MESH:D002493 Central Nervous System Diseases Phenytoin 4.664080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9316129372
MESH:D002659 Child Development Disorders, Pervasive Testosterone 3.4020678186
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.6016835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.0715861022 17681005 11677210 16105132 17333356 16919318 17110522
MESH:D002779 Cholestasis pirinixic acid 6.0719176532
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 5.2111748493
MESH:D002822 Choriocarcinoma Tretinoin 4.4916461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.1115894690
MESH:D002971 Cleft Lip marker/mechanism 17963255
MESH:D002971 Cleft Lip Ethanol 6.6615513904
MESH:D002971 Cleft Lip Phenytoin 6.662227380
MESH:D002972 Cleft Palate marker/mechanism 17963255
MESH:D002972 Cleft Palate Ethanol 11.4515513904
MESH:D002972 Cleft Palate Phenytoin 11.453877104 2227380 6862529 6856622 10789828 1687470
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 11.4515668235 8697196 12621046 16354765 15340226
MESH:D002972 Cleft Palate Tretinoin 11.459407595
MESH:D003072 Cognition Disorders Raloxifene 3.9815800139
MESH:D003092 Colitis Curcumin 7.5216804969 18200517 16782535
MESH:D003092 Colitis Tretinoin 7.5217035595
MESH:D003103 Coloboma Curcumin 9.3618809619
MESH:D003103 Coloboma Phenytoin 9.369212184
MESH:D003110 Colonic Neoplasms Curcumin 6.9419359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 6.9415824018
MESH:D003110 Colonic Neoplasms Fluorouracil 6.9417169374 17725105 17172411 15001691 18772588 16340194 17287894 16510598 17016597 17018589
MESH:D003110 Colonic Neoplasms oxaliplatin 6.9416004971 16024531 16510598
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.1220501625
MESH:D015179 Colorectal Neoplasms Cisplatin 4.1215273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.1215289873 16524972 16282729 18509181 18288408 16303861 17594712 20501625 17094418 15148649 18949393 17695437 17016601 18383874 16391804 17401013 18448328 17454858 16331619 18802399 14970324 17255274
MESH:D015179 Colorectal Neoplasms oxaliplatin 4.1217594712 18509181 17255274 17401013 18448328 17695437
MESH:D000013 Congenital Abnormalities Phenytoin 7.5210627286
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.5214669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.2518497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5612609071
MESH:D019465 Craniofacial Abnormalities marker/mechanism 10631169 16465081 18082115
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 12.3010525206
MESH:D019465 Craniofacial Abnormalities Benzene 12.3015643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 12.3017728286
MESH:D019465 Craniofacial Abnormalities Ethanol 12.3015513904 19302082 10194807 15451039 11873399 15451040 11198716
MESH:D019465 Craniofacial Abnormalities Phenytoin 12.309212184 8986270 19952982
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 12.3015736158
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 12.3015322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 12.309125849 16925845 9664655 17551590 14991402 10589399 8800419 9211117 9224671 9142499
MESH:D003394 Craniofacial Dysostosis marker/mechanism 9152842
MESH:D003398 Craniosynostoses marker/mechanism 8957519 9605588 16465081
OMIM:123790 CUTIS GYRATA SYNDROME OF BEARE AND STEVENSON marker/mechanism 17449949
MESH:D003490 Cyanosis 2,4-dinitrotoluene 8.7718551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 8.7718551238
MESH:D003556 Cystitis Hydrochloric Acid 4.8020719367 12853844 19279288 12599022
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.1417714534
MESH:D007644 Darier Disease Fluorouracil 4.1316733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.4915213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7219031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.6017474826
MESH:D003872 Dermatitis Benzene 4.1315902427
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.3112438553
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.3116780908 16823706 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0818249437
MESH:D003920 Diabetes Mellitus rosiglitazone 7.5617446233
MESH:D003920 Diabetes Mellitus Sodium Selenite 7.5616285004
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 3.8316684804
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 5.9718403477
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 5.9712642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 5.9717107852
MESH:D003928 Diabetic Nephropathies Curcumin 16.8518204486
MESH:D003928 Diabetic Nephropathies Estradiol 16.8519279558
MESH:D003928 Diabetic Nephropathies Raloxifene 16.8515920148 17308373 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 16.8519279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.8517187935
MESH:D003967 Diarrhea Dexamethasone 3.097237001
OMIM:607208 DRAVET SYNDROME Phenytoin 4.7511748493
MESH:D003875 Drug Eruptions Phenytoin 4.8615024534
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 11.9821346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.9821346803 18551238
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 11.986623471 17522070 3732212 15968718 15027814 2869522 10092053 10915739 3786805 7440962 19336974 19085960 15998439 4309450 11566570 16177239 7120509 9327722 21278145 16227642 7179309 6884620
MESH:D056486 Drug-Induced Liver Injury Ethanol 11.9811566570
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 11.9815131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.9820420201
MESH:D004362 Drug Toxicity Cisplatin 6.5015033597 12231392 12649298 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.5011462148
MESH:D004381 Duodenal Ulcer Curcumin 3.4317351913
MESH:D004485 Eczema Dexamethasone 3.8412438553
MESH:D004487 Edema Dexamethasone 23.6919703484
MESH:D004487 Edema Mustard Gas 23.699260866 11428631 11428647 11402378
MESH:D004487 Edema pirinixic acid 23.6912083418
MESH:D004487 Edema Raloxifene 23.6915860553
MESH:D004487 Edema rosiglitazone 23.6912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 23.6912711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 23.6916716910 8273558 15177302 9599246 7812673 8113982 11698051
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.7218230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.7218230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 27.7015138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 27.7012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 27.7017654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 27.7017692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 27.7015845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 27.7019031437
MESH:D016889 Endometrial Neoplasms Estradiol 9.7718566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 9.7716202921 20544844 19155303 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 9.7716569247
MESH:D004715 Endometriosis Progesterone 7.0216134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.0210568697 9294722
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 4.5720235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 5.561399206 6251365
MESH:D004828 Epilepsies, Partial Phenytoin 4.2511558140 17116037
MESH:D004827 Epilepsy Phenytoin 3.5620417680 11434505 821787
MESH:D017029 Epilepsy, Complex Partial Phenytoin 4.667750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 4.413659116
MESH:D004890 Erythema Mustard Gas 4.509357497
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.1419566590
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.4320426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 11.4312903497
MESH:D004938 Esophageal Neoplasms Cisplatin 11.4315173087 16785472 15464296 16481741 17638652
MESH:D004938 Esophageal Neoplasms Ethanol 11.4316704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 11.4316785472 16481741 17638652 16337965 15173087
MESH:D004941 Esophagitis Hydrochloric Acid 5.3412928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.3511346197 14621274 20516732
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.1511564622
MESH:D005124 Eye Abnormalities Tretinoin 7.1516938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 38.2215073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 38.2212795759 17595544 15959796 19224547 16239168 16045604 12631006 61145
MESH:D005234 Fatty Liver Curcumin 38.2219297423
MESH:D005234 Fatty Liver Ethanol 38.2219236843 18620774 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 38.2215345470
MESH:D005234 Fatty Liver pirinixic acid 38.2220131406 19236843
MESH:D005234 Fatty Liver Raloxifene 38.2217473493
MESH:D005234 Fatty Liver rosiglitazone 38.2219196556
MESH:D005234 Fatty Liver Tamoxifen 38.2219224547 14986274
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.9917920746
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.8016709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.6410194807 15513904 16946407 15451040
MESH:D005313 Fetal Death Phenytoin 8.6110627286
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 8.6111858732
MESH:D005334 Fever Dinoprost 4.9511852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.8714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.5319069698
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.5811555667
MESH:D005355 Fibrosis Carbon Tetrachloride 21.0318705752
MESH:D005355 Fibrosis Curcumin 21.0318705752
MESH:D005355 Fibrosis Hydrochloric Acid 21.0318497604
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.0320067830
MESH:D005355 Fibrosis Tretinoin 21.0317994277
MESH:D005391 Firesetting Behavior Testosterone 5.187506515
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6416904648
MESH:D005739 Gas Poisoning Hydrochloric Acid 4.8012378975
MESH:D005756 Gastritis Ethanol 4.0315046732
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.7020616304 19957777 20545468 19951613 20516732 12212954
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.0518462866
MESH:D005885 Gingival Hyperplasia Phenytoin 5.019029455
MESH:D019214 Gingival Overgrowth Phenytoin 5.5614659971 16390469
MESH:D005909 Glioblastoma Curcumin 9.4017596214
MESH:D005909 Glioblastoma Testosterone 9.4017162496
MESH:D005909 Glioblastoma Tretinoin 9.4017312396
MESH:D005910 Glioma Fluorouracil 5.3416145905
MESH:D005910 Glioma Methylnitrosourea 5.349825942
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9210696789
MESH:D006223 Hamartoma Syndrome, Multiple marker/mechanism 9002682
MESH:D006261 Headache Nitroglycerin 4.5211554966 11284996
MESH:D006258 Head and Neck Neoplasms Cisplatin 14.6315464296 15102660
MESH:D006258 Head and Neck Neoplasms Curcumin 14.6318829502 18462866
MESH:D006258 Head and Neck Neoplasms Fluorouracil 14.6318337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Tretinoin 14.6316096774
MESH:D034381 Hearing Loss Cisplatin 3.7419898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.4916084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.8715464296
MESH:D006356 Heartburn Hydrochloric Acid 5.1419566590
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.2411294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 5.249664655 14991402
MESH:D006331 Heart Diseases Raloxifene 3.0611110106
MESH:D006333 Heart Failure pirinixic acid 2.1120558911
MESH:D006402 Hematologic Diseases Benzene 4.0516183116
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7411000095
MESH:D006505 Hepatitis Carbon Tetrachloride 2.9819900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 6.1518467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.1515340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4017701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.807520565
MESH:D006558 Herpes Genitalis Estradiol 4.3615709030
MESH:D006628 Hirsutism Testosterone 4.9817019078
MESH:D006689 Hodgkin Disease Cisplatin 3.0616200630 16170182
MESH:D019584 Hot Flashes Estradiol 3.0917088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3816959395 18606429 16354765 15340226 8697196
MESH:D006930 Hyperalgesia Ethanol 14.4318783367
MESH:D006930 Hyperalgesia oxaliplatin 14.4317418472
MESH:D006930 Hyperalgesia rosiglitazone 14.4312083418
MESH:D006930 Hyperalgesia Tretinoin 14.4316870215
MESH:D017588 Hyperandrogenism Testosterone 4.6417019078
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.8716899240
MESH:D006937 Hypercholesterolemia Curcumin 3.4718704882
MESH:D006940 Hyperemia Hydrochloric Acid 4.9912646421
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9316778211
MESH:D006943 Hyperglycemia pirinixic acid 2.6120558911
MESH:D020138 Hyperhomocysteinemia Phenytoin 4.1110459572
MESH:D006973 Hypertension Benzene 9.9317940673
MESH:D006973 Hypertension Dexamethasone 9.9317042910
MESH:D006973 Hypertension Raloxifene 9.9315787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.9318850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 9.2815338365
MESH:D006975 Hypertension, Portal Hydrochloric Acid 9.2816984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 3.9719262391
MESH:D007006 Hypogonadism Testosterone 4.1012002444
MESH:D007018 Hypopituitarism Testosterone 5.5317426086
MESH:D007021 Hypospadias Ethinyl Estradiol 3.1716945680 16569931
MESH:D007022 Hypotension Hydrochloric Acid 4.1611574821
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 4.7718306037
MESH:D007174 Impulse Control Disorders Testosterone 5.187506515
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.7615869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.4017937319
MESH:D007248 Infertility, Male Methylnitrosourea 5.407193160
MESH:D007249 Inflammation Curcumin 29.3217151092 18403477 16956363
MESH:D007249 Inflammation Dexamethasone 29.328960868 11099482
MESH:D007249 Inflammation Flavonoids 29.3217296493
MESH:D007249 Inflammation Hydrochloric Acid 29.3211574821
MESH:D007249 Inflammation Mustard Gas 29.3216001271 9260866 11428647 8975870 11402378 11428620 11428631 17524151 9357497
MESH:D007249 Inflammation Progesterone 29.3215869954
MESH:D007249 Inflammation rosiglitazone 29.3212083418
MESH:D007249 Inflammation Tamoxifen 29.3219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 29.3212200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 29.3211698051 8273558 7562506 7812673 15177302
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9018200517 18596194
MESH:D007333 Insulin Resistance bisphenol A 18.3516393666
MESH:D007333 Insulin Resistance Estradiol 18.3516393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 18.3516306350
MESH:D007333 Insulin Resistance rosiglitazone 18.3516306350
MESH:D007333 Insulin Resistance Sodium Selenite 18.3514714311
MESH:D007410 Intestinal Diseases Hydrochloric Acid 13.0111574821
MESH:D007410 Intestinal Diseases rebamipide 13.0111686837
MESH:D007410 Intestinal Diseases Tretinoin 13.0117994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.6410783313
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.4119381132
MESH:C537559 Jackson-Weiss syndrome marker/mechanism
MESH:D007569 Jaw Abnormalities Ethanol 13.7615513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 13.7616580747
MESH:D007569 Jaw Abnormalities Tretinoin 13.7615992940 17551590
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 4.7718306037
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.4715464296
MESH:D007674 Kidney Diseases Cisplatin 4.9018289764 12649298 15190930 12231392 19839026
MESH:D007674 Kidney Diseases Estradiol 4.9015618244
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 3.6816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.6116705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.6116705839
MESH:D007680 Kidney Neoplasms Estradiol 17.6115610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.6116985049
MESH:D007680 Kidney Neoplasms Tamoxifen 17.6118625569
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.1311231351
MESH:C538132 Lacrimoauriculodentodigital syndrome marker/mechanism
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 5.6916498863
MESH:D007826 Laryngismus Hydrochloric Acid 5.6911510729
MESH:D007859 Learning Disorders Ethanol 3.5815451040
MESH:D007889 Leiomyoma Curcumin 9.1318555241
MESH:D007889 Leiomyoma Raloxifene 9.1316973256
MESH:D007938 Leukemia arsenic trioxide 11.9315070760
MESH:D007938 Leukemia Benzene 11.9318335105 15935818 14694614 17119257
MESH:D007938 Leukemia Curcumin 11.9318462866
MESH:D007938 Leukemia Tretinoin 11.9317143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 7.8017077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 7.8016106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.9314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 12.6319077051
MESH:D007951 Leukemia, Myeloid Benzene 12.6317506065
MESH:D007951 Leukemia, Myeloid Tretinoin 12.6316482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.2016467208 16968895 19850784 17050201 20471514
MESH:D015470 Leukemia, Myeloid, Acute Benzene 5.2019478238
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.2016294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.1111161223 9834237 15336539 16112521 16330433 15213294 17869043 17649720 12679006 19642359 15622746 17712046 19225113 16823087 16966277 12712474 15748426 11468182 19035177 17107899 16331271 16891316 12018890 19075265 17217047
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.1116891316 17368321 17107899 16766008 19075265 15748426 17361223 17217047 16788101 16331271 17712046 19225113 19035177 17301526 17649720 19029980 17294898 16140955 19642359 17506722 9834237 12679006 17339181 16935935 16823087
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.6416882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.6416106398
MESH:D017880 Limb Deformities, Congenital marker/mechanism 10631169
MESH:D017880 Limb Deformities, Congenital Ethanol 10.9617676605
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 10.9615526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 10.969224671
MESH:D008064 Lipidoses Tamoxifen 2.6717567588 15342952
MESH:D008103 Liver Cirrhosis marker/mechanism 17692400
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 8.9111903743 16239168 16943688 16221502 17334410 17157831 11408273 21278145 17174718
MESH:D008103 Liver Cirrhosis Ethanol 8.9115289165
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 8.9116984587
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.4418295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 17.9117557913 16192424 12666154 15876570 14620537 12445421 17481882 16027843 12389079 20821823 18472094 12632512 17922224 18205269 12898905 15052691 17698563 16248980 17761835 15996030 15818738 18187930 15673190 16116963 17708605 12741479 12632514 18481824 12546737 12609069 15931870 18395095 15370692 18412020 14512876 17631135 17823541 17900296 17869086 12958196 14716496 18705752 12445418 15338365 15730626 16097048 17714472 17721639 18054572 18156304 18376398 17766677 16136751 12586293 18251166 18317297 15925388 15057751 12649538 10355542 18395914 14724832 16638106 17944888 18006644 18166357 17976157 18210741 18277467 15123356 18263696 18339082 14748882 11481614 14716833 15893842 18472332 16033810 16015684 17565644 16011737 15362042 15959796 18429990 18418968 13678700 17805973 15650968 18420326 12667390 18279442 17525996 17640975
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 17.9117355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 17.9116718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 17.9114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 17.9118166357
MESH:D008106 Liver Cirrhosis, Experimental Heparin 17.9116904936
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 17.9115474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 17.9117347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 17.9118564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 17.9112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 17.9118397230 16248980
MESH:D008107 Liver Diseases Carbon Tetrachloride 7.6415720792 16964402 17285989 16246199 15830285
MESH:D008107 Liver Diseases Chlorpyrifos 7.6415991261
MESH:D008107 Liver Diseases Curcumin 7.6416956363
MESH:D008107 Liver Diseases Phenytoin 7.6414986274
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.0117347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.1114706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.247678174
MESH:D008113 Liver Neoplasms arsenic trioxide 17.2414682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.2419294768
MESH:D008113 Liver Neoplasms Fluorouracil 17.2418383874 17045692 15113037 16603448
MESH:D008113 Liver Neoplasms pirinixic acid 17.2420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 17.2416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.2416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.982876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.9820377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 13.9812562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.9815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.9812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8415213294
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 4.8216080182
MESH:D008171 Lung Diseases Hydrochloric Acid 6.4016784557
MESH:D008171 Lung Diseases Mustard Gas 6.4018161513 18702808
MESH:D017563 Lung Diseases, Interstitial Benzene 4.1414698565
MESH:D055370 Lung Injury Hydrochloric Acid 4.1319262391 16129981 21114838 18573544 18497604 18339021 19644408 15044056 17627322 15090967 21311175 11395602 20597076 15607125
MESH:D008175 Lung Neoplasms arsenic trioxide 20.0311798837 19825857
MESH:D008175 Lung Neoplasms Benzene 20.0312562636
MESH:D008175 Lung Neoplasms Cisplatin 20.0311798837 6189445 17225452
MESH:D008175 Lung Neoplasms Curcumin 20.0319359593 18462866 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 20.0315824018 11195469
MESH:D008175 Lung Neoplasms Fluorouracil 20.0315246190
MESH:D008175 Lung Neoplasms Methylnitrosourea 20.0318062963
MESH:D008175 Lung Neoplasms Mustard Gas 20.038781369 3148597
MESH:D008175 Lung Neoplasms Tamoxifen 20.0318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 20.0311884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 20.0311807781
MESH:D008175 Lung Neoplasms tipifarnib 20.0316885199
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.1315086387
MESH:D008223 Lymphoma Benzene 9.9317119257 17584886
MESH:D008223 Lymphoma Curcumin 9.9318462866
MESH:D008223 Lymphoma Methylnitrosourea 9.9316257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 8.4314633661
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 8.4314737004
MESH:D016399 Lymphoma, T-Cell Curcumin 4.0516173963
MESH:D015674 Mammary Neoplasms, Animal Benzene 7.9012562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.9019428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 29.8011921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 29.8011807958 16891317 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental estradiol 3-benzoate 29.8015375486
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 29.8015313902 19196723 11751437 16051031 10767621 14999141 16619500 17020996 12931682 15688392 15113128 10838139 11807958 17131329 14633655 16827153 16944150
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 29.8017203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 29.8016827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 29.8014580682 19196723 11731420 16827153 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 29.808985016
MESH:D008325 Mammary Neoplasms, Experimental tipifarnib 29.8016648579
MESH:D020149 Manganese Poisoning Estradiol 10.4219453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.4219453300
MESH:D008527 Medulloblastoma Tretinoin 2.4817453147
MESH:D008545 Melanoma Cisplatin 8.0512374674 16809738 12883367 16432458 18332650 15577323 11135225 12393984 18176117 18505091 17761969 17023156 16248763
MESH:D008545 Melanoma Curcumin 8.0517885582 18462866
MESH:D008545 Melanoma Reactive Oxygen Species 8.0517992120
MESH:D008545 Melanoma Tamoxifen 8.0519393235 12393984
MESH:D008545 Melanoma Tretinoin 8.0516752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 9.3315990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 9.3315990972
MESH:D008569 Memory Disorders Curcumin 7.6917263510
MESH:D008569 Memory Disorders Ethanol 7.6918411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 3.7816940565
MESH:D008607 Mental Retardation marker/mechanism 16465081
MESH:D008607 Mental Retardation Phenytoin 3.419212184
MESH:D008654 Mesothelioma Cisplatin 2.9417638057
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.8317261469
MESH:D008708 Methemoglobinemia Nitroglycerin 4.133537620
MESH:D020326 Migraine without Aura Nitroglycerin 4.5014659530
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.8815863610
MESH:D019957 Motor Skills Disorders marker/mechanism 16465081
MESH:D009062 Mouth Neoplasms Fluorouracil 3.1218986760 16757204
MESH:D009101 Multiple Myeloma arsenic trioxide 17.5015949261 19417148 19549372 11468182 14977855
MESH:D009101 Multiple Myeloma Benzene 17.5017119195
MESH:D009101 Multiple Myeloma Curcumin 17.5019372569
MESH:D009101 Multiple Myeloma Dexamethasone 17.5016118317 15867202 15744524
MESH:D009101 Multiple Myeloma Raloxifene 17.5016497877
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.2617962980
MESH:D009135 Muscular Diseases pirinixic acid 2.8716239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 9.9616882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 9.969809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 9.9617596541
MESH:D009203 Myocardial Infarction Hydrochloric Acid 7.8418534312
MESH:D009203 Myocardial Infarction Nitroglycerin 7.8414729435
MESH:D009203 Myocardial Infarction pirinixic acid 7.8419151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.4912213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 6.5316810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.5316411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 4.8717484760
MESH:D009224 Myotonia Congenita Phenytoin 4.751896199
MESH:D009232 Myxoma Raloxifene 4.8816343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.1718551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.177678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.2516624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.2518495463
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.2519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2619410462
MESH:D009369 Neoplasms Cisplatin 11.8116773208
MESH:D009369 Neoplasms Fluorouracil 11.8118239605 18600527 16928823
MESH:D009369 Neoplasms Methylnitrosourea 11.8115533788
MESH:D009369 Neoplasms pirinixic acid 11.8117405874
MESH:D009369 Neoplasms Tretinoin 11.8116594593 16946489
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 3.8412696579
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.6212497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.6219200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0817289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.8315464296
MESH:D009421 Nervous System Malformations bisphenol A 18.3316427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 18.3316427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.3314600291
MESH:D009421 Nervous System Malformations Tretinoin 18.339125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.9618462866
MESH:D009436 Neural Tube Defects arsenic trioxide 13.6510525206
MESH:D009436 Neural Tube Defects Benzene 13.6515643154
MESH:D009436 Neural Tube Defects Phenytoin 13.659118846
MESH:D009436 Neural Tube Defects Tretinoin 13.659142499
MESH:D009442 Neurilemmoma Methylnitrosourea 4.8311555667
MESH:D009447 Neuroblastoma Cisplatin 3.078761367
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.048761367
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 6.7415081274
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 6.7416436463
MESH:D009503 Neutropenia Mustard Gas 3.3716761898 7688884
MESH:D009765 Obesity Curcumin 3.8919297423
MESH:D009765 Obesity pirinixic acid 3.8920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 16.9512819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 16.9516049721
MESH:D009784 Occupational Diseases Benzene 16.9517119257 15612468 17178637 15935809 17479406 15727169 15576619 16737584 15913788
MESH:D009784 Occupational Diseases Hydrochloric Acid 16.9512378975
MESH:D010018 Osteomalacia Phenytoin 4.7517016548
MESH:D010024 Osteoporosis Curcumin 5.9618719352
MESH:D010024 Osteoporosis Raloxifene 5.9617882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.6217893378 15579764 15758505 17823083
MESH:D010049 Ovarian Diseases bisphenol A 4.3311985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 18.9016624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Benzene 18.9012562636
MESH:D010051 Ovarian Neoplasms Cisplatin 18.906897625 19769630 15464296 17225452
MESH:D010051 Ovarian Neoplasms Curcumin 18.9019020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 18.9019401270
MESH:D010051 Ovarian Neoplasms Progesterone 18.9017393432 16525653
MESH:D010051 Ovarian Neoplasms Tretinoin 18.9016936753
MESH:D010146 Pain Phenytoin 5.4115215642
MESH:D010146 Pain Tretinoin 5.4116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 28.2515580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 28.2519003803
MESH:D010190 Pancreatic Neoplasms Curcumin 28.2517440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms Ethanol 28.2512384795
MESH:D010190 Pancreatic Neoplasms Fluorouracil 28.2519003803 16929163 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 28.2516965848
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 28.2515580305
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 28.2515976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 28.2515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0811578682
MESH:D010212 Papilloma cumene hydroperoxide 12.1917234724 12065085
MESH:D010212 Papilloma Hydrogen Peroxide 12.1912065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 12.1912065085 18404319 18922899 8330346
MESH:D010235 Paraganglioma arsenic trioxide 3.5519927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5812520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.6915464296
MESH:D049068 Plagiocephaly, Nonsynostotic marker/mechanism 9152842
MESH:D010997 Pleural Neoplasms Cisplatin 4.6717638057
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 4.7215970105 18497604 18573544 15607125
MESH:D011041 Poisoning Mustard Gas 3.2015727166
MESH:D017689 Polydactyly Phenytoin 4.489212184
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9318163543
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.1421297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 7.3410548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.3411896295 11399792 11118676 11222880
MESH:D011470 Prostatic Hyperplasia BXL628 10.7916957418 15572423
MESH:D011470 Prostatic Hyperplasia Calcitriol 10.7915572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 14.6320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 14.6320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Testosterone 14.6320887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.1019131511
MESH:D011471 Prostatic Neoplasms bisphenol A 3.1016740699
MESH:D011471 Prostatic Neoplasms Calcitriol 3.1016289102 15754350 18247401 12479363 16644109
MESH:D011471 Prostatic Neoplasms Curcumin 3.1018156803 10851300 11398177 15129424 12497104 18226269 18769126
MESH:D011471 Prostatic Neoplasms Estradiol 3.1016740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.1018626508 19082440
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 3.1015682402 12376480
MESH:D011471 Prostatic Neoplasms Raloxifene 3.1015731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.1018760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.1015067354
MESH:D011507 Proteinuria Tretinoin 3.0016636307
MESH:D011537 Pruritus Ethinyl Estradiol 7.3616919318 15861022
MESH:D011537 Pruritus Mustard Gas 7.3618058305
MESH:D019310 Pseudolymphoma Phenytoin 4.8712752131 1419762 8603615
MESH:D011625 Pterygium Tretinoin 4.1316723453
MESH:D011629 Puberty, Precocious bisphenol A 4.1310548101
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.3520597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.5515090967
MESH:D011656 Pulmonary Emphysema Curcumin 3.9519168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.6417620002 10334151 17720292 17894541 17266442
MESH:D011693 Purpura Raloxifene 4.8815770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.4515538739 16160472 18286688 18722050
MESH:D051437 Renal Insufficiency Cisplatin 3.7715464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.0319058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 11.8718379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 11.8718379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 11.8717627322 18339021 16784557 18549715 16129981
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 5.6911510729
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.0016611668 17119214 11874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2118990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 8.9216611668 17119214
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 8.9220516732
MESH:D012162 Retinal Degeneration Methylnitrosourea 3.9018155124 18172121
MESH:D012175 Retinoblastoma Methylnitrosourea 4.8311555667
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.4916283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5818045962
MESH:D012509 Sarcoma Curcumin 3.5418462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.2716646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 8.2714601052
OMIM:609579 SCAPHOCEPHALY, MAXILLARY RETRUSION, AND MENTAL RETARDATION marker/mechanism
MESH:D012640 Seizures 2,4-dinitrotoluene 10.2918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 10.2918551238
MESH:D012640 Seizures Ethanol 10.299754883
MESH:D012640 Seizures Phenytoin 10.2919919933 10029267 3691417 3137016 9844417 11044598 16876388 15946322
MESH:D018805 Sepsis Curcumin 3.5318389075
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 5.426418539
MESH:D012735 Sexual Dysfunction, Physiological Testosterone 5.5316631401
MESH:D012851 Sinus Thrombosis, Intracranial Heparin 5.4112269725
MESH:D012868 Skin Abnormalities marker/mechanism 10631169
MESH:D012871 Skin Diseases Mustard Gas 2.5112880345 15451306 16961503
MESH:D012878 Skin Neoplasms cumene hydroperoxide 14.1712065085 17234724 8532709
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 14.1712065085
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 14.1716192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 14.1718404319 8985016 8330346 12065085 11807781
MESH:D012878 Skin Neoplasms Tretinoin 14.1716467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.6715464296
MESH:D013088 Spermatocele Ethinyl Estradiol 9.3416709447
MESH:D013088 Spermatocele Tamoxifen 9.3416709447
MESH:D013119 Spinal Cord Injuries Progesterone 8.7016503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 8.7019457130
MESH:D016135 Spinal Dysraphism marker/mechanism 9605588
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 4.5120235791
MESH:D013272 Stomach Diseases Dexamethasone 8.5115472012
MESH:D013272 Stomach Diseases rebamipide 8.5116184426
MESH:D013274 Stomach Neoplasms marker/mechanism
MESH:D013274 Stomach Neoplasms arsenic trioxide 10.8117007042
MESH:D013274 Stomach Neoplasms Benzene 10.8112562636
MESH:D013274 Stomach Neoplasms Cisplatin 10.8115958060 18396642 17522103
MESH:D013274 Stomach Neoplasms Ethanol 10.8118456281
MESH:D013274 Stomach Neoplasms Fluorouracil 10.8117522103 15786421 16424979 17498489 16951190 18396642 19015929 19084572 18567086 17172411
MESH:D013274 Stomach Neoplasms Methylnitrosourea 10.8116257854 18593901 15930296
MESH:D013274 Stomach Neoplasms rebamipide 10.8115993841
MESH:D013274 Stomach Neoplasms Tretinoin 10.8117261132
MESH:D013276 Stomach Ulcer Curcumin 12.4819188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 12.4815138204
MESH:D013276 Stomach Ulcer Ethanol 12.489211565 16755016 17189318 11906479 9562338 17918041
MESH:D013276 Stomach Ulcer Hydrochloric Acid 12.4817189318 15309881 16755016
MESH:D020521 Stroke Raloxifene 3.2916837676
MESH:D019966 Substance-Related Disorders bisphenol A 3.3316045194 16684133
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.689754883
MESH:D013736 Testicular Neoplasms Cisplatin 4.0215464296 17225452
MESH:D013921 Thrombocytopenia Heparin 4.8816893407 16651880
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 7.6315669648
MESH:D013927 Thrombosis Heparin 7.6316893407
MESH:D013953 Thymus Neoplasms Benzene 10.0510850423
MESH:D013953 Thymus Neoplasms Methylnitrosourea 10.0511418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2312697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 9.1419014326
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 9.147505956 3078959
MESH:D013964 Thyroid Neoplasms Tretinoin 9.1416026305 17045167
MESH:D013978 Tibial Fractures Estradiol 11.4919048282
MESH:D013978 Tibial Fractures Raloxifene 11.4919048282
MESH:D014062 Tongue Neoplasms Fluorouracil 7.9116280240
MESH:D014062 Tongue Neoplasms Tretinoin 7.9116051514
MESH:D014071 Tooth Abnormalities marker/mechanism 10631169
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3115213294
MESH:D014376 Tuberculosis Tretinoin 2.7916040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 19.3716049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 19.3716049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 19.3711780464 12845720 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 19.3712973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Curcumin 19.3718593936
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 19.3717572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 19.3717572228 8653321 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.6118462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.8110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.8110091137
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 12.5916803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 12.5916803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 12.5916129372
MESH:D014591 Uterine Diseases bisphenol A 4.3414652134
MESH:D014594 Uterine Neoplasms Benzene 7.5012562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.5014692618
MESH:D014604 Uveal Neoplasms Tretinoin 3.9416752155
MESH:D014605 Uveitis Dexamethasone 4.151336536
MESH:D014625 Vaginal Neoplasms Cisplatin 3.9715577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9212125929
MESH:D014657 Vasculitis Heparin 5.4120337814
MESH:D054556 Venous Thromboembolism Raloxifene 4.5416837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9514671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.4316761959
MESH:D014839 Vomiting Cisplatin 4.0511897121
MESH:D014846 Vulvar Neoplasms Raloxifene 4.8816343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5815886252
MESH:D009396 Wilms Tumor Tretinoin 3.4016287080
Pathway ID Pathway Name
KEGG:04144 Endocytosis
KEGG:04010 MAPK signaling pathway
KEGG:05200 Pathways in cancer
KEGG:05215 Prostate cancer
KEGG:04810 Regulation of actin cytoskeleton
REACT:9470 Signaling by FGFR
REACT:498 Signaling by Insulin receptor
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28128
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    PA443560Breast Neoplasms
    Releated drug ID Related drug Name
    PA452359progestogens and estrogens in combination
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00039 binder Palifermin Antimucositis Agents
    DB01041 antagonist Thalidomide Immunosuppressive Agents;Leprostatic Agents;Teratogens;Angiogenesis Inhibitors
    DB02058 - SU4984
    DB02491 - 4-[4-(1-Amino-1-Methylethyl)Phenyl]-5-Chloro-N-[4-(2-Morpholin-4-Ylethyl)Phenyl]Pyrimidin-2-Amine
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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