AutismKB 2.0

Annotation Detail for NID2


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Basic Information Top
Gene Symbol:NID2 ( NID-2 )
Gene Full Name: nidogen 2 (osteonidogen)
Band: 14q22.1
Quick LinksEntrez ID:22795; OMIM: 605399; Uniprot ID:NID2_HUMAN; ENSEMBL ID: ENSG00000087303; HGNC ID: 13389
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1848Embryoma
1934Cancer
Desease Name
CARDIOVASCULAR
pulmonary function traits (other)
Desease Name
Pulmonary function traits (other)
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of NID2 mRNAdecreases expression 18648102
D001149 Arsenates [Atrazine co-treated with Arsenates] results in increased expression of NID2 mRNAaffects cotreatment|increases expression 18585445
D001280 Atrazine [Atrazine co-treated with Arsenates] results in increased expression of NID2 mRNAaffects cotreatment|increases expression 18585445
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NID2 mRNAaffects cotreatment|increases expression 18164116
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of NID2 mRNAaffects expression 17484886
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of NID2 mRNAaffects cotreatment|decreases expression 16054899
D004041 Dietary Fats Dietary Fats results in increased expression of NID2 mRNAincreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NID2 mRNAaffects cotreatment|increases expression 18164116
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of NID2 mRNAincreases expression 15171707
D002117 Calcitriol Calcitriol results in decreased expression of NID2 mRNAdecreases expression 16002434
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of NID2 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of NID2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of NID2 mRNAaffects cotreatment|decreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of NID2 mRNAdecreases expression 17557909
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of NID2 mRNAaffects cotreatment|decreases expression 16054899
D008942 Mitoxantrone NID2 protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
C041786 palm oil palm oil results in increased expression of NID2 mRNAincreases expression 18042831
D010656 Phenylephrine Phenylephrine results in increased expression of NID2 mRNAincreases expression 18158353
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NID2 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NID2 mRNAaffects binding|increases activity|increases expression 19710929
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of NID2 mRNAaffects cotreatment|decreases expression 16054899
C010327 salinomycin salinomycin results in decreased expression of NID2 mRNAdecreases expression 19682730
D012643 Selenium Selenium results in decreased expression of NID2 mRNAdecreases expression 19244175
D013629 Tamoxifen Tamoxifen affects the expression of NID2 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of NID2 mRNAaffects cotreatment|decreases expression 17942748
D014635 Valproic Acid Valproic Acid results in increased expression of NID2 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.8815322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.888875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8119490988
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9918653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7814692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.783712494
MESH:D000236 Adenoma beta-Naphthoflavone 10.7819389873
MESH:D000236 Adenoma Diethylnitrosamine 10.786695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.5218056438 19061943 17162532 19052882 16434500 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.5216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.5216835633
MESH:D000382 Agricultural Workers' Diseases Atrazine 4.1011874814
MESH:D000544 Alzheimer Disease rosiglitazone 2.8219621015
MESH:D000550 Amblyopia Valproic Acid 5.1017688650
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3515469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D001008 Anxiety Disorders Valproic Acid 3.4717497229
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.0017460149
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Dexamethasone 7.1117659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1115885639
MESH:D001321 Autistic Disorder Valproic Acid 2.0216609825 18316065 17157402 20603192 17688650 18985861 18940202 15238991 18177632 18558336 19232924 17507914 18396377 19460635 18775368
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.891440618 11289319
MESH:D001714 Bipolar Disorder Valproic Acid 3.0117594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.3712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.7415746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.748888407
MESH:D001919 Bradycardia Phenylephrine 4.4115306635
MESH:D001943 Breast Neoplasms Calcitriol 3.6911237771
MESH:D001943 Breast Neoplasms Dietary Fats 3.6920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.6917474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 3.6915324884 17129689
MESH:D001943 Breast Neoplasms salinomycin 3.6919682730
MESH:D001943 Breast Neoplasms Tamoxifen 3.6919189210 17440819 18629630 19487384 19059307 17242785 11161223 20065188 19155303 19289846 16273361 20544844 18351453 19288272 19221464 16873071 19142967 18997820 19011961 18821012 20135344 20859285 18855134 21138602 19189212 18425577 19084267 16818667 19244106 20390343 16202921 15565566 18815881 19115204 17893378 19066611 19103187 18984771 17049068 19200415 15668708 19410462 21152245 17261762 20005174
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6920435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6516227642 16050911 16097048 16011737 15673190 16124888 18705752 16192424 15721981 10355542 15700767 3786805
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3819066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.653581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.6518788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.6520935162 19052882 20524982 16569478 16779866 18210153 18056438 17978847 16681979 19418558 16540662 20727157 18494052 16878318 19335982 20512989 19107877 19171122 16807293 18506893 21159647 16935385 18785209 10737359 19822196 17138121 20101231 20214788 16830150 18971187 17162532 18788625 16698587 17761372 17428255 19919837 20007298 3084413 19519916 20514400 18691550 10672840 18978308 18665156 20432363 19208518 19701751 17173139 19539802 16288022 19383236 17055752 20084675 16328049 19394651 16502159 3581430 18393292 11831363
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 8.6516924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.6516924424
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.617296757
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 2.5911237771
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5017572228
MESH:D006332 Cardiomegaly Phenylephrine 6.6417124262 16170337 15728586 17287366 11754973 11179087
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6418850075 18670907 16120746
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.397505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.392727394 17174075 7505956 21159647
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6620734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.9519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.9516835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.819022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.8117110522 16105132 15861022 16919318 17681005 17333356 11677210
MESH:D002779 Cholestasis pirinixic acid 12.8119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0512621046 8697196 16354765 15340226 15668235
MESH:D003092 Colitis Selenium 3.6517936198
MESH:D003110 Colonic Neoplasms Dexamethasone 2.4715824018
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9517141729 14669216
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.7417728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7415322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.748888407 17688650 16575769
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.4316002989 12952375
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2319031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 6.6214531868 8970840 11906362 11298694 18759878 2524372 12868966 8156756
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 6.6212438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3718249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.373621924 2952479
MESH:D003920 Diabetes Mellitus rosiglitazone 4.1917446233
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.9820387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.9812642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.3619279558
MESH:D003967 Diarrhea Dexamethasone 3.577237001
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 14.7618648102 7440962 9653073 18289764 6482804 18692083 9022650 1440618 8291058 9328219 11289319 16192314 6679447
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 14.767120509 16177239 6623471 4309450 15998439 15968718 19336974 9327722 3786805 16227642 11566570 7179309 15027814 19085960 7440962 2869522 10092053 17522070 3732212 10915739 21278145 6884620
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.7619107877
MESH:D056486 Drug-Induced Liver Injury Selenium 14.7615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.7620420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 14.761733752 19641884
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:D004421 Dystonia Valproic Acid 3.921851702
MESH:D004485 Eczema Dexamethasone 4.3312438553
MESH:D004487 Edema Dexamethasone 15.4819703484
MESH:D004487 Edema pirinixic acid 15.4812083418
MESH:D004487 Edema rosiglitazone 15.4812083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 15.4812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7716714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 14.6015138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.6012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.6019031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.5616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.2816804899 15700306
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.2819155303 20544844 16202921 17893378
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9110568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.023659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.7916628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8718234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.487562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.177750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.933659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.083581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9111564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 41.3412631006 17595544 15959796 61145 16045604 19224547 12795759 16239168
MESH:D005234 Fatty Liver Dietary Fats 41.3419004024 17967931 18296743 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 41.3420387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 41.3415345470
MESH:D005234 Fatty Liver pirinixic acid 41.3420131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 41.3419196556
MESH:D005234 Fatty Liver Tamoxifen 41.3419224547 14986274
MESH:D005234 Fatty Liver Valproic Acid 41.3414986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.9516611131 16002989 16534752 16513791 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.9516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005315 Fetal Diseases Valproic Acid 4.7616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.0018558336 8888407
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.896705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0519069698
MESH:D005355 Fibrosis Carbon Tetrachloride 14.0118705752
MESH:D005355 Fibrosis Dietary Fats 14.0118296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.0120067830
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.8216452187
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.917505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2611294989 10048152
MESH:D006331 Heart Diseases Mitoxantrone 4.0616019553
MESH:D006333 Heart Failure pirinixic acid 6.6820558911
MESH:D006333 Heart Failure Selenium 6.6817162251
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.806705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.8019110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 7.8319176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.8315340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.037520565
MESH:D006849 Hydrocephalus Valproic Acid 4.7417688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9216354765 16959395 15340226 18606429 8697196
MESH:D006930 Hyperalgesia rosiglitazone 3.8112083418
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4016899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D006943 Hyperglycemia pirinixic acid 3.0720558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 10.4015034207
MESH:D006965 Hyperplasia Diethylstilbestrol 10.4012960047 14722030
MESH:D006973 Hypertension Dexamethasone 8.4317042910
MESH:D006973 Hypertension Phenylephrine 8.4312717712 8949925
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.4318670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9615338365
MESH:D006984 Hypertrophy Phenylephrine 4.4318502941 12791704
MESH:D007021 Hypospadias Diethylstilbestrol 10.8116002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.8116569931 16945680
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.3118306037
MESH:D007246 Infertility Diethylstilbestrol 4.2315036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Atrazine 6.6212948887
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.6217937319
MESH:D007249 Inflammation Dexamethasone 19.1011099482 8960868
MESH:D007249 Inflammation Dietary Fats 19.1020412841
MESH:D007249 Inflammation Diethylnitrosamine 19.1018785209
MESH:D007249 Inflammation rosiglitazone 19.1012083418
MESH:D007249 Inflammation Tamoxifen 19.1019457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 19.1012878042 12200463
MESH:D007251 Influenza, Human Selenium 4.0716624496
MESH:D007333 Insulin Resistance Dietary Fats 11.9111836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 11.9116306350
MESH:D007333 Insulin Resistance rosiglitazone 11.9116306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.899022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2116580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.3118306037
MESH:D007676 Kidney Failure, Chronic Selenium 3.7616518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.856582329
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 11.8515003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Tamoxifen 11.8518625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.9317184923
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.7318172266
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1316294345 17596541
MESH:D008064 Lipidoses Tamoxifen 3.0615342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.6017174718 11408273 17157831 16943688 21278145 11903743 17334410 16239168 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 10.6018296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.6018522880 18407596 20032147 19638242 18665156
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.1115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.5318156304 18481824 17805973 18277467 17761835 16097048 18395914 14724832 15370692 15123356 16248980 17721639 16136751 12666154 16027843 18317297 18210741 18395095 17869086 17823541 18429990 17565644 17481882 15052691 18412020 18279442 17557913 17976157 18418968 17944888 12898905 20821823 18251166 18187930 12649538 18263696 12546737 16192424 14512876 12741479 15730626 14716496 12445418 14716833 12667390 12609069 16638106 18420326 16015684 18705752 17922224 18339082 17708605 17766677 14620537 13678700 15876570 17900296 18006644 18472332 17640975 12632512 15925388 18205269 17525996 16116963 18472094 16011737 17698563 12958196 17714472 12586293 18376398 15650968 15673190 11481614 12389079 15893842 15931870 15362042 18054572 10355542 12445421 15959796 15338365 14748882 12632514 17631135 15818738 18166357 16033810 15057751 15996030
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 8.5316718785
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.5315474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 8.5315980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.5318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.5312878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9615830285 15720792 17285989 16964402 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9617034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0315123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5716899240 14706259
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 21.1519389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 21.1519294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.1519427195 18754104 21047994 21278145 19690152 19090486 19996281 18648771 19833225 19499222 10737359 18977376 19642983 19812893 21167192 19850985 9163691 19551842 20501860 20118626 16942905 20434301 2862719 19294768 20583210 18644402 19255062 15175105 15885732 20137499 19256749 12771043 20405173 19254457 18978307 20452335 19426721 2422723 20492335 20101389 21071580 19638242 19073162 12112319
MESH:D008113 Liver Neoplasms Diethylstilbestrol 21.1515890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 21.1515890375 20007298 16377806
MESH:D008113 Liver Neoplasms Tamoxifen 21.1516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.1516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 17.78598648 6587162 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 17.7818164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.7812014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.783124819 16267830 19126423 18775883 19519916 2563599 21159647 18544905 19004024 17854601 17942915 19009564 17174075 19539802 9362446 18079962 18093689 18164116 18282651 18308698 18253720 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.7812151625
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.1317228818
MESH:D008175 Lung Neoplasms Dexamethasone 4.7211195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.7220970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Tamoxifen 4.7218625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.7211884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.0215166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.3815700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.3916002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6319428831
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 13.6716827153
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 13.6719682730
MESH:D008325 Mammary Neoplasms, Experimental Selenium 13.6715318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 13.6714580682 19196723 11731420 19196722 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.4219453300
MESH:D008545 Melanoma Tamoxifen 1.8619393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0515990972
MESH:D008654 Mesothelioma Atrazine 6.291916698
MESH:D008654 Mesothelioma Selenium 6.2915107826
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.2717261469
MESH:D008881 Migraine Disorders Valproic Acid 3.1018765137 18803445
MESH:D009101 Multiple Myeloma Dexamethasone 3.4115867202 15744524 16118317
MESH:D009135 Muscular Diseases pirinixic acid 3.3816239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.918888407
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 7.329809623
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.3217596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8416411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.163581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.169029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.1619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4719410462
MESH:D009369 Neoplasms Diethylstilbestrol 8.0315313581
MESH:D009369 Neoplasms Mitoxantrone 8.0316640825
MESH:D009369 Neoplasms pirinixic acid 8.0317405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8719189210 19196722 19200415
MESH:D009421 Nervous System Malformations Diethylstilbestrol 9.2211399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.2214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.976679447
MESH:D009436 Neural Tube Defects Valproic Acid 6.9716359493 8888407
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2320387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D009765 Obesity Dietary Fats 4.3220518802 11836018 19632207 18457598 18674790 16723640 20132043 21332399 17217161
MESH:D009765 Obesity pirinixic acid 4.3220558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.306482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.893988306
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.3816540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.357296757
MESH:D010300 Parkinson Disease Atrazine 3.2317218051
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.346228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.0414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.5415687265 16977796
MESH:D010954 Plasmacytoma Selenium 4.7615087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.442563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.4721297632
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 15.5117184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.5111118676 11222880 11896295 11399792
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 15.5120603192
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.6515572423
MESH:D011471 Prostatic Neoplasms Calcitriol 2.6812479363 16289102 16644109 18247401 15754350
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.6817136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.6815067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.1815861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.4112752131 11422049
MESH:D015427 Reperfusion Injury pirinixic acid 2.3219058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.8911700416 18379247
MESH:D012135 Respiratory Sounds Atrazine 4.3911874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.283692021
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.0519155313
MESH:D012559 Schizophrenia Valproic Acid 2.0515737665 19110320
MESH:D012640 Seizures Valproic Acid 2.6514763951 3137016 17978042 1511512 16876388 11044598 11738929 15475178
MESH:D012852 Sinusitis Phenylephrine 4.577327846
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9816192470
MESH:D013088 Spermatocele Diethylstilbestrol 19.3916709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 19.3916709447
MESH:D013088 Spermatocele Tamoxifen 19.3916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9119457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6819490988
MESH:D013226 Status Epilepticus Valproic Acid 4.4112833885
MESH:D013272 Stomach Diseases Dexamethasone 4.1915472012
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013276 Stomach Ulcer Dexamethasone 3.3715138204
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.793712494 6582329 7505956 1399818 6587162
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.797505956
MESH:D014178 Translocation, Genetic Valproic Acid 5.1017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.393119515
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.068074119
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.0617306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.0617572228 16712894 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.518888407
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.9216175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.0414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.0515809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.0514692618
MESH:D014605 Uveitis Dexamethasone 4.691336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.3116002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4214671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA31626
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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