Annotation Detail for ITGA11
Basic Information
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| Pathway ID | Pathway Name |
|---|
| hsa05410 | Hypertrophic cardiomyopathy (HCM) |
| hsa05412 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
| hsa05414 | Dilated cardiomyopathy |
| hsa04810 | Regulation of actin cytoskeleton |
| hsa04512 | ECM-receptor interaction |
| hsa04510 | Focal adhesion |
| Pathway ID | Pathway Name |
|---|
| Integrin cell surface interactions |
| Pathway ID | Pathway Name |
|---|
| P00034 | Integrin signalling pathway |
| Desease ID | Desease Name |
|---|
| 1848 | Embryoma |
| 1934 | Cancer |
| Desease Name |
|---|
| ADHD |
| CANCER |
| PSYCH |
| attention-deficit hyperactivity disorder |
| lung cancer |
| Desease Name |
|---|
| Attention deficit hyperactivity disorder |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C472791 |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of ITGA11 mRNA | decreases expression | 12958071
|
| C099555 |
CD 437 |
CD 437 results in decreased expression of ITGA11 mRNA | decreases expression | 12958071
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of ITGA11 mRNA | increases expression | 20106945
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.82 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.24 | 19486331 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.34 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.79 | 12639820 12168785 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.96 | 8708960 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.16 | 15720958 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.23 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.31 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.56 | 18776723 10903974 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.12 | 12371664 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.65 | 16801185 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.31 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.70 | 18481113 19348381 |
| MESH:D010051 |
Ovarian Neoplasms |
|
CD 437 |
3.42 | 17474084 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.64 | 12371664 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.34 | 16882103 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
CD 437 |
3.52 | 16720286 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.85 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.31 | 17120751 |
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