AutismKB 2.0

Annotation Detail for NLGN4Y


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Basic Information Top
Gene Symbol:NLGN4Y ( KIAA0951 )
Gene Full Name: neuroligin 4, Y-linked
Band: Yq11.221
Quick LinksEntrez ID:22829; OMIM: 400028; Uniprot ID:NLGNY_HUMAN; ENSEMBL ID: ENSG00000165246; HGNC ID: 15529
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2001Mental retardation
2124Autistic disorder
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D012643 Selenium Selenium results in increased expression of NLGN4Y mRNAincreases expression 18583539
C024746 tobacco tar tobacco tar results in decreased expression of NLGN4Y mRNAdecreases expression 19559774
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 4.2719559774
MESH:D003092 Colitis Selenium 4.5417936198
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2715131321
MESH:D006333 Heart Failure Selenium 3.3417162251
MESH:D007251 Influenza, Human Selenium 5.2716624496
MESH:D007676 Kidney Failure, Chronic Selenium 4.4416518626
MESH:D008325 Mammary Neoplasms, Experimental Selenium 3.0515318939
MESH:D008654 Mesothelioma Selenium 2.9415107826
MESH:D010954 Plasmacytoma Selenium 5.9615087411
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
Pharmacogenomics Knowledge Base Top
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018