AutismKB 2.0

Annotation Detail for ADNP2


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Basic Information Top
Gene Symbol:ADNP2 ( KIAA0863,ZNF508 )
Gene Full Name: ADNP homeobox 2
Band: 18q23
Quick LinksEntrez ID:22850; OMIM: NA; Uniprot ID:ADNP2_HUMAN; ENSEMBL ID: ENSG00000101544; HGNC ID: 23803
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ADNP2 mRNAdecreases expression 20382639
20018196
19150397
D016572 Cyclosporine Cyclosporine results in increased expression of ADNP2 mRNAincreases expression 20106945
D008094 Lithium Lithium results in increased expression of ADNP2 mRNAincreases expression 19949822
C004648 testosterone enanthate testosterone enanthate affects the expression of ADNP2 mRNAaffects expression 17440010
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000544 Alzheimer Disease Lithium 3.5319621015
MESH:D001714 Bipolar Disorder Lithium 4.4919153942 20338123 17594078 20046352
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.4412371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D007644 Darier Disease Lithium 6.5420338123
MESH:D018500 Diabetes Insipidus, Nephrogenic Lithium 6.3119244398
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D005234 Fatty Liver Cyclosporine 3.2819224547
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006330 Heart Defects, Congenital Lithium 4.3919638421
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.4717440010
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.548314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009203 Myocardial Infarction Lithium 4.0616288908
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6518481113 19348381
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D012640 Seizures Lithium 4.2419660546
MESH:D013226 Status Epilepticus Lithium 6.5119430551 19570321 19951488
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018